Xenobiotic metabolism induction and bulky DNA adducts generated by particulate matter pollution in BEAS-2B cell line: geographical and seasonal influence

Journal of Applied Toxicology

Volumn 34, Issue 6, 2014, Pages 703-713

  Lepers, Capucine ^a,b   André, Véronique ^c,d,e   Dergham, Mona ^a,b   Billet, Sylvain ^a,b   Verdin, Anthony ^a,b   Garçon, Guillaume ^a,b   Dewaele, Dorothée ^a,f   Cazier, Fabrice ^a,f   Sichel, François ^c,d,e   Shirali, Pirouz ^a,b  

^a UNIV LILLE   (France)

^b UNIVERSITÉ DU LITTORAL CÔTE D OPALE   (France)

^c NORMANDIE UNIVERSITÉ   (France)

^d Envtl   (France)

^e CENTRE FRANÇOIS BACLESSE   (France)

^f UNIVERSITÉ DU LITTORAL CÔTE D OPALE   (France)

Author keywords

BEAS 2B; Bulky DNA adducts; Emission sources; Particulate Matter; Polycyclic aromatic hydrocarbons metabolism

Indexed keywords

ALUMINUM; ANTHRACENE; BARIUM ION; BENZO[A]PYRENE; BENZO[GHI]PERYLENE; BENZ[A]ANTHRACENE; CHROMIUM; CHRYSENE; COPPER; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DNA; ETHOXYRESORUFIN DEETHYLASE; FERROUS ION; FLUORANTHENE; FLUORENE; LEAD; MANGANESE; MESSENGER RNA; METAL; NAPHTHALENE; NICKEL; POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE; TITANIUM; TRANSITION ELEMENT; XENOBIOTIC AGENT; ZINC; CYP1A1 PROTEIN, HUMAN; CYP1B1 PROTEIN, HUMAN; DNA ADDUCT; PARTICULATE MATTER;

AIR POLLUTION; ARTICLE; BRONCHUS MUCOSA; BULKY DNA ADDUCT; CATALYSIS; CHEMICAL COMPOSITION; CONTROLLED STUDY; DNA ADDUCT; ENZYME ACTIVITY; ENZYME INDUCTION; EPITHELIUM CELL; GENOTOXICITY; GEOGRAPHIC DISTRIBUTION; HUMAN; HUMAN CELL; INDUSTRIAL AREA; METABOLIC ACTIVATION; PARTICULATE MATTER; PRIORITY JOURNAL; RURAL AREA; SEASONAL VARIATION; SUMMER; URBAN AREA; WINTER; XENOBIOTIC METABOLISM; BIOSYNTHESIS; CELL LINE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; LUNG; METABOLISM; MULTIVARIATE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; SEASON; TIME; TOXICITY;

CELL LINE; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1B1; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; EPITHELIAL CELLS; HUMANS; LUNG; METALS; MULTIVARIATE ANALYSIS; PARTICULATE MATTER; POLYCYCLIC HYDROCARBONS, AROMATIC; PRINCIPAL COMPONENT ANALYSIS; RNA, MESSENGER; SEASONS; TIME FACTORS;

EID: 84899643500     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2931     Document Type: Article

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