Soluble platelet-endothelial cell adhesion molecule-1, a biomarker of ventilator-induced lung injury

Critical Care

Volumn 18, Issue 2, 2014, Pages

  Villar, Jesús ^a,b,c   Muros, Mercedes ^a,d   Cabrera Benítez, Nuria E ^a,b   Valladares, Francisco ^a,e   López Hernández, Milagros ^e   Flores, Carlos ^a,d   Martín Barrasa, José L ^a,b   Blanco, Jesús ^a,f   Liu, Mingyao ^g,h   Kacmarek, Robert M ^i,j  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b HOSPITAL UNIVERSITARIO DE GRAN CANARIA DR NEGRÍN   (Spain)

^c ST MICHAEL'S HOSPITAL   (Canada)

^d HOSPITAL UNIVERSITARIO NUESTRA SEÑORA DE CANDELARIA   (Spain)

^e UNIVERSIDAD DE LA LAGUNA   (Spain)

^f HOSPITAL UNIVERSITARIO RÍO HORTEGA   (Spain)

^g UNIVERSITY OF TORONTO   (Canada)

^h UNIVERSITY HEALTH NETWORK   (Canada)

ⁱ MASSACHUSETTS GENERAL HOSPITAL   (United States)

^j HARVARD UNIVERSITY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; SOLUBLE PLATELET ENDOTHELIAL CELL ADHESION MOLECULE 1; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREATHING; CELL ADHESION; CONTROLLED STUDY; ENDOTHELIUM CELL; GAS EXCHANGE; HISTOPATHOLOGY; IMMUNOBLOTTING; INFLAMMATORY INFILTRATE; INJURY SEVERITY; LUNG INJURY; LUNG PRESSURE; LUNG VENTILATION; MALE; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; RAT; SYSTEMIC CIRCULATION; TIDAL VOLUME; VENTILATOR INDUCED LUNG INJURY; ANIMAL; BLOOD; LUNG; METABOLISM; PATHOLOGY; RANDOMIZATION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIGENS, CD31; BIOLOGICAL MARKERS; LUNG; MALE; PROSPECTIVE STUDIES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; VENTILATOR-INDUCED LUNG INJURY;

EID: 84899641148     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc13754     Document Type: Article

References (45)

1. Pinhu L, Whiteheaqd T, Evans T, Griffiths M. Ventilator-associated lung injury. Lancet 2003, 361:332-340. 10.1016/S0140-6736(03)12329-X, 12559881.
2. Dreyfuss D, Saumon G. Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 1998, 157:294-323. 10.1164/ajrccm.157.1.9604014, 9445314.
3. Burns KE, Adhikari NK, Slutsky AS, Guyatt GH, Villar J, Zhang H, Zhou Q, Cook DJ, Stewart TE, Meade MO. Pressure and volume limited ventilation for the ventilatory management of patients with acute lung injury: a systematic review and meta-analysis. PLoS One 2011, 6:e14623. 10.1371/journal.pone.0014623, 3030554, 21298026.
4. Villar J, Blanco J, Zhang H, Slutsky AS. Ventilator-induced lung injury and sepsis: two sides of the same coin?. Minerva Anestesiol 2011, 77:647-653.
5. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000, 342:1301-1308.
6. Villar J, Herrera-Abreu MT, Valladares F, Muros M, Pérez-Méndez L, Flores C, Kacmarek RM. Experimental ventilator-induced lung injury. Exacerbation by positive end-expiratory pressure. Anesthesiology 2009, 110:1341-1347.
7. Crosby LM, Waters CM. Epithelial repair mechanisms in the lung. Am J Physiol Lung Cell Mol Physiol 2010, 298:L715-L731. 10.1152/ajplung.00361.2009, 2886606, 20363851.
8. Nonas SA, Moreno-Vinasco L, Ma SF, Jacobson JR, Desai AA, Dudek SM, Flores C, Hassoun PM, Sam L, Ye SQ, Moitra J, Barnard J, Grigoryev DN, Lussier YA, Garcia JG. Use of consomic rats for genomic insights into ventilator-associated lung injury. Am J Physiol Lung Cell Mol Physiol 2007, 293:L292-L302. 10.1152/ajplung.00481.2006, 3616407, 17468131.
9. Hegeman MA, Hennus MP, Heijnen CJ, Specht PA, Lachmann B, Jansen NJ, van Vught AJ, Cobelens PM. Ventilator-induced endothelial activation and inflammation in the lung and distal organs. Crit Care 2009, 13:R182. 10.1186/cc8168, 2811914, 19917112.
10. Villar J, Cabrera N, Casula M, Flores C, Valladares F, Muros M, Blanch L, Slutsky AS, Kacmarek RM. Mechanical ventilation modulates Toll-like receptor signaling pathway in a sepsis-induced lung injury model. Intensive Care Med 2010, 36:1049-1057. 10.1007/s00134-010-1799-3, 20397011.
11. Villar J, Cabrera NE, Casula M, Flores C, Valladares F, Diaz-Flores L, Muros M, Slutsky AS, Kacmarek RM. Mechanical ventilation modulates TLR4 and IRAK-3 in a non-infectious, ventilator-induced lung injury model. Respir Res 2010, 11:27. 10.1186/1465-9921-11-27, 2841148, 20199666.
12. Woodfin A, Voisin MB, Nourshargh S. PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler Thromb Vasc Biol 2007, 27:2514-2523. 10.1161/ATVBAHA.107.151456, 17872453.
13. Ilan N, Mohsenin A, Cheung L, Madri JA. PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristics. FASEB J 2001, 15:362-372. 10.1096/fj.00-0372com, 11156952.
14. Fornasa G, Groyer E, Clement M, Dimitrov J, Compain C, Gaston AT, Varthaman A, Khallou-Laschet J, Newman DK, Graff-Dubois S, Nicoletti A, Caligiuri G. TCR stimulation drives cleavage and shedding of the ITIM receptor CD31. J Immunol 2010, 184:5485-5492. 10.4049/jimmunol.0902219, 3110943, 20400708.
15. Villar J, Cabrera NE, Casula M, Valladares F, Flores C, López-Aguilar J, Blanch L, Zhang H, Kacmarek RM, Slutsky AS. WNT/β-catenin signalling is modulated by mechanical ventilation in an experimental model of acute lung injury. Intensive Care Med 2011, 37:1201-1209. 10.1007/s00134-011-2234-0, 21567117.
16. Parker JC, Hernandez LA, Peevy KJ. Mechanisms of ventilator-induced lung injury. Crit Care Med 1993, 21:131-143. 10.1097/00003246-199301000-00024, 8420720.
17. Tremblay LN, Slutsky AS. Ventilator-induced lung injury: from the bench to the bedside. Intensive Care Med 2006, 32:24-33. 10.1007/s00134-005-2817-8, 16231069.
18. Fu Z, Costello ML, Tsukimoto K, Prediletto R, Elliott AR, Mathieu-Costello O, West JB. High lung volume increases stress failure in pulmonary capillaries. J Appl Physiol 1992, 73:123-133.
19. Pujin J. Is the ventilator responsible for lung and systemic inflammation?. Intensive Care Med 2002, 28:817-819. 10.1007/s00134-002-1320-8, 12349817.
20. Webb HH, Tierney DF. Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure. Am Rev Respir Dis 1974, 110:556-565.
21. Herrera MT, Toledo C, Valladares F, Muros M, Diaz-Flores L, Flores C, Villar J. Positive end-expiratory pressure modulates local and systemic inflammatory responses in a sepsis-induced lung injury model. Intensive Care Med 2003, 29:1345-1353. 10.1007/s00134-003-1756-5, 12698249.
22. Newman PJ. The biology of PECAM-1. J Clin Invest 1997, 100:S25-S29. 10.1172/JCI119517, 9413397.
23. Newman PJ, Berndt MC, Gorski J, White GC, Lyman S, Paddock C, Muller WA. PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 1990, 247:1219-1222. 10.1126/science.1690453, 1690453.
24. Privratsky JR, Paddock CM, Florey O, Newman DK, Muller WA, Newman PJ. Relative contribution of PECAM1 adhesion and signaling to the maintenance of vascular integrity. J Cell Sci 2011, 124:1477-1485. 10.1242/jcs.082271, 3078814, 21486942.
25. Graesser D, Solowiej A, Bruckner M, Osterweil E, Juedes A, Davis S, Ruddle NH, Engelhardt B, Madri JA. Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice. J Clin Invest 2002, 109:383-392. 10.1172/JCI0213595, 150854, 11827998.
26. Mahooti S, Graesser D, Patil S, Newman P, Duncan G, Mak T, Madri JA. PECAM-1 (CD31) expression modulates bleeding time in vivo. Am J Pathol 2000, 157:75-81. 10.1016/S0002-9440(10)64519-1, 1850208, 10880378.
27. Muller AM, Cronen C, Muller KM, Kirkpatrick CJ. Heterogeneous expression of cell adhesion molecules by endothelial cells in ARDS. J Pathol 2002, 198:270-275. 10.1002/path.1186, 12237888.
28. Bhatia RK, Pallister I, Dent C, Jones SA, Topley N. Enhanced neutrophil migratory activity following major blunt trauma. Injury 2005, 36:956-962. 10.1016/j.injury.2005.03.009, 15998513.
29. Bhatt AJ, Pryhuber GS, Huyck H, Watkins RH, Metlay LA, Maniscalco WM. Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001, 164:1971-1980. 10.1164/ajrccm.164.10.2101140, 11734454.
30. Krauss T, Kuhn W, Lakoma C, Augustin HG. Circulating endothelial cell adhesion molecules as diagnostic markers for the early identification of pregnant women at risk for development of preeclampsia. Am J Obst Gynecol 1997, 177:443-449.
31. Soriano AO, Jy W, Chirinos JA, Valdivia MA, Velasquez HS, Jimenez JJ, Horstman LL, Kett DH, Schein RM, Ahn YS. Levels of endothelial and platelet microparticles and their interactions with leukocytes negatively correlate with organ dysfunction and predict mortality in severe sepsis. Crit Care Med 2005, 33:2540-2546. 10.1097/01.CCM.0000186414.86162.03, 16276178.
32. Densmore JC, Signorino PR, Ou J, Hatoum OA, Rowe JJ, Shi Y, Kaul S, Jones DW, Sabina RE, Pritchard KA, Guice KS, Oldham KT. Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury. Shock 2006, 26:464-471. 10.1097/01.shk.0000228791.10550.36, 17047516.
33. Amabile N, Heiss C, Real WM, Minasi P, McGlothlin D, Rame EJ, Grossman W, De Marco T, Yeghiazarians Y. Circulating endothelial microparticle levels predict hemodynamic severity of pulmonary hypertension. Am J Respir Crit Care Med 2008, 177:1268-1275. 10.1164/rccm.200710-1458OC, 18310479.
34. Sinning JM, Losch J, Walenta K, Böhm M, Nickenig G, Werner N. Circulating CD31+/Annexin V + microparticles correlate with cardiovascular outcomes. Eur Heart J 2011, 32:2034-2041. 10.1093/eurheartj/ehq478, 21186238.
35. Buras JA, Holzmann B, Sitkovsky M. Animal models of sepsis: setting the stage. Nat Rev Drug Discov 2005, 4:854-865. 10.1038/nrd1854, 16224456.
36. Goldberger A, Middleton KA, Oliver JA, Paddock C, Yan HC, DeLisser HM, Albelda SM, Newman PJ. Biosynthesis and processing of the cell adhesion molecule PECAM1 includes production of a soluble form. J Biol Chem 1994, 269:17183-17191.
37. Muller WA, Weigl SA, Deng X, Phillips DM. PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 1993, 178:449-460. 10.1084/jem.178.2.449, 2191108, 8340753.
38. Shehabi Y, Seppelt I. Pro/Con debate: is procalcitonin useful for guiding antibiotic decision making in critically ill patients?. Crit Care 2008, 12:211. 10.1186/cc6860, 2481434, 18466649.
39. Chiumello D, Carlesso E, Cadringher P, Caironi P, Valenza F, Polli F, Tallarini F, Cozzi P, Cressoni M, Colombo A, Marini JJ, Gattinoni L. Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome. Am J Respir Crit Care Med 2008, 178:346-355. 10.1164/rccm.200710-1589OC, 18451319.
40. Protti A, Cressoni M, Santini A, Langer T, Mietto C, Febres D, Chierichetti M, Coppola S, Conte G, Gatti S, Leopardi O, Masson S, Lombardi L, Lazzerini M, Rampoldi E, Cadringher P, Gattinoni L. Lung stress and strain during mechanical ventilation: any safe threshold?. Am J Respir Crit Care Med 2011, 183:1354-1362. 10.1164/rccm.201010-1757OC, 21297069.
41. Slutsky AS, Ranieri VM. Ventilator-induced lung injury. N Engl J Med 2013, 369:2126-2136. 10.1056/NEJMra1208707, 24283226.
42. Maas M, Stapleton M, Bergom C, Mattson DL, Newman DK, Newman PJ. Endothelial cell PECAM-1 confers protection against endotoxic shock. Am J Physiol Heart Circ Physiol 2005, 288:H159-H164.
43. Bhattacharya S, Sen N, Yiming MT, Patel R, Parthasarathi K, Quadri S, Issekutz AC, Bhattacharya J. High tidal volume ventilation induces proinflammatory signaling in rat lung endothelium. Am J Respir Cell Mol Biol 2003, 28:218-224. 10.1165/rcmb.4763, 12540489.
44. Tsukimoto K, Mathieu-Costello O, Prediletto R, Elliott AR, West JB. Ultrastructural appearances of pulmonary capillaries at high transmural pressures. J Appl Physiol 1991, 71:573-582.
45. López-Aguilar J, Piacentini E, Villagrá A, Murias G, Pascotto S, Saenz-Valiente A, Fernández-Segoviano P, Hotchkiss JR, Blanch L. Contributions of vascular flow and pulmonary capillary pressure to ventilator-induced lung injury. Crit Care Med 2006, 34:1106-1112. 10.1097/01.CCM.0000205757.66971.DA, 16484897.