Gq/5-HT2c receptor signals activate a local GABAergic inhibitory feedback circuit to modulate serotonergic firing and anxiety in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 17, 2014, Pages 6479-6484

  Spoida, Katharina ^a   Masseck, Olivia A ^a   Deneris, Evan S ^b   Herlitze, Stefan ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; G PROTEIN COUPLED RECEPTOR; MELANOPSIN; SEROTONIN; SEROTONIN 2C RECEPTOR; SEROTONIN RECEPTOR; CALCIUM; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; SCOTOPSIN;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; BRAIN REGION; CARBOXY TERMINAL SEQUENCE; CELL STRUCTURE; DOWN REGULATION; FEEDBACK SYSTEM; GABAERGIC SYSTEM; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; MOOD DISORDER; MOUSE; NEGATIVE FEEDBACK; NEUROTRANSMISSION; NONHUMAN; OPTOGENETICS; PRIORITY JOURNAL; SEROTONINERGIC NERVE CELL; SEROTONINERGIC SYSTEM; SIGNAL TRANSDUCTION; ACTION POTENTIAL; ANIMAL; CHEMISTRY; HEK293 CELL LINE; LIGHT; METABOLISM; NERVE CELL INHIBITION; PATHOLOGY; PATHOPHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; RADIATION EXPOSURE; RAPHE NUCLEUS;

ACTION POTENTIALS; ANIMALS; ANXIETY; CALCIUM; DOWN-REGULATION; FEEDBACK, PHYSIOLOGICAL; GABAERGIC NEURONS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEK293 CELLS; HUMANS; INTRACELLULAR SPACE; LIGHT; MICE; NEURAL INHIBITION; OPTOGENETICS; PROTEIN STRUCTURE, TERTIARY; RAPHE NUCLEI; RECEPTOR, SEROTONIN, 5-HT2C; ROD OPSINS; SEROTONIN; SIGNAL TRANSDUCTION;

EID: 84899640850     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1321576111     Document Type: Article

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