-
1
-
-
0036138580
-
Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
-
DOI 10.1200/JCO.20.1.289
-
Motzer RJ, Bacik J, Murphy BA, et al: Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol 20:289-296, 2002 (Pubitemid 34032623)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.1
, pp. 289-296
-
-
Motzer, R.J.1
Bacik, J.2
Murphy, B.A.3
Russo, P.4
Mazumdar, M.5
-
2
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
Hudes G, Carducci M, Tomczak P, et al: Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 356:2271-2281, 2007 (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
3
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
Escudier B, Eisen T, Stadler WM, et al: Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356:125-134, 2007 (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
4
-
-
33748590610
-
Phase III randomized trial of sunitinib malate versus interferon-alfa (IFN-α) as first-line systemic therapy for patients with metastatic renal cell carcinoma
-
abstr LBA3
-
Motzer RJ, Hutson TE, Tomczak P, et al: Phase III randomized trial of sunitinib malate versus interferon-alfa (IFN-α) as first-line systemic therapy for patients with metastatic renal cell carcinoma. J Clin Oncol 24, 2006 (suppl; abstr LBA3)
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
5
-
-
84899630091
-
Randomized phase III trial of temsirolimus and bevacizumab versus interferon alfa and bevacizumab in metastatic renal cell carcinoma: INTORACT trial
-
Rini BI, Bellmunt J, Clancy J, et al: Randomized phase III trial of temsirolimus and bevacizumab versus interferon alfa and bevacizumab in metastatic renal cell carcinoma: INTORACT trial. J Clin Oncol 32:752-759, 2014
-
(2014)
J Clin Oncol
, vol.32
, pp. 752-759
-
-
Rini, B.I.1
Bellmunt, J.2
Clancy, J.3
-
6
-
-
84899679988
-
Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma
-
Hutson TE, Escudier B, Esteban E, et al: Randomized phase III trial of temsirolimus versus sorafenib as second-line therapy after sunitinib in patients with metastatic renal cell carcinoma. J Clin Oncol 32:760-767, 2014
-
(2014)
J Clin Oncol
, vol.32
, pp. 760-767
-
-
Hutson, T.E.1
Escudier, B.2
Esteban, E.3
-
8
-
-
84860121016
-
Assumptions of expected benefits in randomized phase III trials evaluating systemic treatments for cancer
-
Gan HK, You B, Pond GR, et al: Assumptions of expected benefits in randomized phase III trials evaluating systemic treatments for cancer. J Natl Cancer Inst 104:590-598, 2012
-
(2012)
J Natl Cancer Inst
, vol.104
, pp. 590-598
-
-
Gan, H.K.1
You, B.2
Pond, G.R.3
-
9
-
-
79959549917
-
Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): A randomised phase 2 trial
-
Négrier S, Gravis G, Perol D, et al: Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): A randomised phase 2 trial. Lancet Oncol 12:673-680, 2011
-
(2011)
Lancet Oncol
, vol.12
, pp. 673-680
-
-
Négrier, S.1
Gravis, G.2
Perol, D.3
-
10
-
-
84895782404
-
The BEST trial (E2804): A randomized phase II study of VEGF, RAF kinase, and mTOR combination targeted therapy (CTT) with bevacizumab (bev), sorafenib (sor), and temsirolimus (tem) in advanced renal cell carcinoma (RCC)
-
abstr 345
-
McDermott DF, Manola J, Pins M, et al: The BEST trial (E2804): A randomized phase II study of VEGF, RAF kinase, and mTOR combination targeted therapy (CTT) with bevacizumab (bev), sorafenib (sor), and temsirolimus (tem) in advanced renal cell carcinoma (RCC). J Clin Oncol 31, 2013 (suppl; abstr 345)
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL.
-
-
McDermott, D.F.1
Manola, J.2
Pins, M.3
-
11
-
-
67349163859
-
Sequential sorafenib and sunitinib for renal cell carcinoma
-
discussion 34
-
Sablin MP, Negrier S, Ravaud A, et al: Sequential sorafenib and sunitinib for renal cell carcinoma. J Urol 182:29-34; discussion 34, 2009
-
(2009)
J Urol
, vol.182
, pp. 29-34
-
-
Sablin, M.P.1
Negrier, S.2
Ravaud, A.3
-
12
-
-
79955705800
-
Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression
-
Zhang L, Bhasin M, Schor-Bardach R, et al: Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression. PLoS One 6:e19144, 2011
-
(2011)
PLoS One
, vol.6
-
-
Zhang, L.1
Bhasin, M.2
Schor-Bardach, R.3
-
13
-
-
77953467629
-
Reversible epithelial to mesenchymal transition and acquired resistance to sunitinib in patients with renal cell carcinoma: Evidence from a xenograft study
-
Hammers HJ, Verheul HM, Salumbides B, et al: Reversible epithelial to mesenchymal transition and acquired resistance to sunitinib in patients with renal cell carcinoma: Evidence from a xenograft study. Mol Cancer Ther 9:1525-1535, 2010
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1525-1535
-
-
Hammers, H.J.1
Verheul, H.M.2
Salumbides, B.3
-
14
-
-
76249133170
-
Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma
-
Huang D, Ding Y, Zhou M, et al: Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. Cancer Res 70:1063-1071, 2010
-
(2010)
Cancer Res
, vol.70
, pp. 1063-1071
-
-
Huang, D.1
Ding, Y.2
Zhou, M.3
-
15
-
-
84860355062
-
Randomized phase II trial of sunitinib on an intermittent versus continuous dosing schedule as firstline therapy for advanced renal cell carcinoma
-
Motzer RJ, Hutson TE, Olsen MR, et al: Randomized phase II trial of sunitinib on an intermittent versus continuous dosing schedule as firstline therapy for advanced renal cell carcinoma. J Clin Oncol 30:1371-1377, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 1371-1377
-
-
Motzer, R.J.1
Hutson, T.E.2
Olsen, M.R.3
-
16
-
-
84891713447
-
Tivozanib versus sorafenib as initial targeted therapy for patients with metastatic renal cell carcinoma: Results from a phase III trial
-
Motzer RJ, Nosov D, Eisen T, et al: Tivozanib versus sorafenib as initial targeted therapy for patients with metastatic renal cell carcinoma: Results from a phase III trial. J Clin Oncol 31:3791-3799, 2013
-
(2013)
J Clin Oncol
, vol.31
, pp. 3791-3799
-
-
Motzer, R.J.1
Nosov, D.2
Eisen, T.3
-
17
-
-
84905696509
-
Progression-free survival as a surrogate endpoint of overall survival in patients with metastatic renal cell carcinoma
-
epub ahead of print on October 8, 2013
-
Halabi S, Rini B, Escudier B, et al: Progression-free survival as a surrogate endpoint of overall survival in patients with metastatic renal cell carcinoma. Cancer [epub ahead of print on October 8, 2013]
-
Cancer
-
-
Halabi, S.1
Rini, B.2
Escudier, B.3
|