Total phenolics, antioxidant and xanthine oxidase inhibitory activity of three colored onions (Allium cepa L.)

Frontiers in Life Science

Volumn 7, Issue 3-4, 2013, Pages 224-228

  Nile, Shivraj Hariram ^a   Park, Se Won ^a  

^a Konkuk University   (South Korea)

Author keywords

antioxidant; flavonoids; inhibition; onions; xanthine oxidase

Indexed keywords

EID: 84899584648     PISSN: 21553769     EISSN: 21553777     Source Type: Journal    
DOI: 10.1080/21553769.2014.901926     Document Type: Article

References (30)

1. Abhayawick L, Laguerre JC, Tauzin V, Duquenoy A. 2002. Physical properties of three onion varieties as affected by the moisture content. J Food Engg. 55:253-262. doi: 10.1016/S0260-8774(02)00099-7
2. Ali M, Thompson M, Afzal M. 2000. Garlic and onions: their effect on eicosanoid metabolism and its clinical relevance. Prostaglandins Leukot Essent Fatty Acids. 62:55-73. doi: 10.1054/plef.1999.0124
3. 2+ system on the corrosion of carbon steel in ground water. Engineering. 5:178-183. doi: 10.4236/eng.2013.52025
4. Barakade AJ, Lokhande TN. 2011. Medicinal uses of onion: an important vegetable crop in India. Vision Res Rev. 1:68-76.
5. Benítez V, Mollá E, Martín-Cabrejas M, Aguilera Y, López-Andréu F, Cools K, Terry L, Esteban R. 2011. Characterization of industrial onion wastes (Allium cepa L): dietary fibre and bioactive compounds. Plant Foods Human Nutr. 66:48-57. doi: 10.1007/s11130-011-0212-x
6. Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. 2007. Antioxidant supplements are used for prevention of several diseases. The J Am Med Assoc. 297:842-857. doi: 10.1001/jama.297.8.842
7. Chopra M, Fitzsimons PE, Strain JJ, Thurnham DI, Howard AN. 2000. Nonalcoholic red wine extract and quercetin inhibit LDL oxidation without affecting plasma antioxidant vitamin and carotenoids concentrations. Clin Chem. 46:1162-1170.
8. Góngora L, Máñez S, Giner RM, Recio MC, Schinella G, Ríos JL. 2003. Inhibition of xanthine oxidase by phenolic conjugates of methylated quinic acid. Planta Med. 69:396-401. doi: 10.1055/s-2003-39715
9. Hanaee J, Rashidi MR, Delazar A, Piroozpanah S. 2004. Onion, a potent inhibitor of xanthine oxidase. Iranian J Pharmaceutical Res. 4:243-247.
10. Hoorn DECV, Nijiveldt RJ, Leeuwen PAMV, Hofman Z, M'Rabet L, Bont DBAD, Norren KV. 2002. Accurate prediction of xanthine oxidase inhibition based on the structure of flavonoids. Eur J Pharmacol. 451:111-118. doi: 10.1016/S0014-2999(02)02192-1
11. Jang M, Leonid A, Nile SH, Keum YS, Kim HY, Park SW. 2013. Ultrasound-assisted extraction of quercetin from onion solid wastes. Int J Food Sci Technol. 48:246-252. doi: 10.1111/j.1365-2621.2012.03180.x
12. Kukongviriyapan V, Janyacharoen T, Kukongviriyapan U, Laupattarakasaem P, Kanokmedhakul S, Chantaranothai P. 2003. Hepatoprotective and antioxidant activities of Tetracera loureiri. Phytother Res. 17:717-721. doi: 10.1002/ptr.1138
13. Lanzotti V. 2006. The analysis of onion and garlic. J Chromatogr A. 1112:3-22. doi: 10.1016/j.chroma.2005.12.016
14. Lee SU, Lee JH, Choi SH, Lee JS, Kameyama MO, Kozukue N, Levin CE, Friedman M. 2008. Flavonoid content in fresh, home-processed, and light-exposed onions and in dehydrated commercial onion products. J Agric Food Chem. 56: 8541-8548. doi: 10.1021/jf801009p
15. Nemeth K, Piskula MK. 2007. Food content, processing, absorption and metabolism of onion flavonoids. Crit Rev Food Sci Nutr. 47:397-409. doi: 10.1080/10408390600846291
16. Nile SH, Khobragade CN. 2009. Determination of nutritive value and mineral elements of some important medicinal plants from western part of India. J Med Plants. 8: 79-88.
17. Nile SH, Khobragade CN. 2011a. In vitro anti-inflammatory and xanthine oxidase inhibitory activity of Tephrosia purpurea shoot extract. Nat Product Comm. 6:1437-1440.
18. Nile SH, Khobragade CN. 2011b. Phytochemical analysis, antioxidant and xanthine oxidase inhibitory activity of Tephrosia purpurea L, root extract. Indian J Natural Products Resources. 2:52-58.
19. Nile SH, Khobragade CN, Park SW. 2012. Optimized and comparative antioxidant assays and its application in herbal and synthetic drug analysis as an antioxidants. Mini-Reviews in Med Chem. 2012, 12:1007-1014. doi: 10.2174/138955712802762310
20. Nile SH, Kumar B, Park SW. 2013. In vitro evaluation of selected benzimidazole derivatives as an antioxidant and xanthine oxidase inhibitors. Chem Biol Drug Des. 82: 290-295. doi: 10.1111/cbdd.12141
21. Pacher P, Nivorozhkin A, Szabo C. 2006. Therapeutic effect of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev. 58: 87-114. doi: 10.1124/pr.58.1.6
22. Prakash D, Singh BN, Upadhyay G. 2007. Antioxidant free radical scavenging activities of fenol from onion (Allium cepa). Food Chem. 102:1389-1393.
23. Prior RL, Wu X, Schaich K. 2005. Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements. J Agric Food Chem. 53:4290-4302. doi: 10.1021/jf0502698
24. Rodriguez GB, Tascon RC, Rodriguez EM, Diaz RC. 2009. Fructans and major compounds in onion cultivars (Allium cepa). J Food Comp Anal. 22:25-32.
25. Salgado BS, Monteiro LN, Rocha NS. 2011. Allium species poisoning in dogs and cats. J Venon Anim Toxins Incl Trop Dis. 17:4-11. doi: 10.1590/S1678-91992011000100002
26. Santas J, Carbó R, Gordon MH, Almajano MP. 2008. Comparison of the antioxidant activity of two Spanish onion varieties. Food Chem. 107:1210-1216. doi: 10.1016/j.foodchem.2007.09.056
27. Takano Y, Hase-Aoki K, Horiuchi H, Zhao L, Kasahara Y, Kondo S, Becker MA. 2005. Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase. Life Sci. 76:1835-1847. doi: 10.1016/j.lfs.2004.10.031
28. Tapas AR, Sakarkar DM, Kakde RB. 2008. Flavonoids as nutraceuticals: a review. Tropical J Pharmaceut Res. 7: 1089-1099.
29. Vertuani S, Angusti A, Manfredini S. 2004. The antioxidants and pro-antioxidants network: an overview. Curr Pharma Des. 10:1677-1694. doi: 10.2174/1381612043384655
30. Yang J, Meyers KJ, Van Der Heide J, Liu RH. 2004. Varietal differences in phenolic content and antioxidant and antiproliferative activities of onions. J Agric Food Chem. 52:6787-6793. doi: 10.1021/jf0307144