Effects of paracetamol on NOS, COX, and CYP activity and on oxidative stress in healthy male subjects, rat hepatocytes, and recombinant NOS

Oxidative Medicine and Cellular Longevity

Volumn 2014, Issue , 2014, Pages

  Trettin, Arne ^a   Böhmer, Anke ^a   Suchy, Maria Theresia ^a   Probst, Irmelin ^b   Staerk, Ulrich ^a   Stichtenoth, Dirk O ^a   Frölich, Jürgen C ^a   Tsikas, Dimitrios ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE; OXIDATIVE STRESS; RATS;

ANALGESIC DRUGS; CYCLOOXYGENASES; CYTOCHROME P450; NITRIC-OXIDE SYNTHASE; PARACETAMOL; RAT HEPATOCYTES; REACTIVE OXYGEN SPECIES; URINARY METABOLITES;

DRUG PRODUCTS;

CYTOCHROME P450; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PARACETAMOL; PROSTACYCLIN; PROSTAGLANDIN SYNTHASE; RECOMBINANT PROTEIN; THROMBOXANE;

ADULT; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HUMAN; LIVER CELL; MALE; METABOLISM; MIDDLE AGED; OXIDATIVE STRESS; RAT;

ACETAMINOPHEN; ADULT; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; EPOPROSTENOL; HEPATOCYTES; HUMANS; MALE; MIDDLE AGED; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RECOMBINANT PROTEINS; THROMBOXANES;

EID: 84899583364     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2014/212576     Document Type: Article

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