-
1
-
-
84858282874
-
Accelerating resistance, inadequate antibacterial drug pipelines and international responses
-
J
-
Theuretzbacher U. Accelerating resistance, inadequate antibacterial drug pipelines and international responses [J]. Int J Antimicrob Agents, 2012, 39: 295-299.
-
(2012)
Int J Antimicrob Agents
, vol.39
, pp. 295-299
-
-
Theuretzbacher, U.1
-
2
-
-
84893089095
-
Prospects for new antibiotics: A molecule-centered perspective
-
J
-
Walsh CT, Wencewicz TA. Prospects for new antibiotics: a molecule-centered perspective [J]. J Antibiot, 2013, http://dx.doi.org/10.1038/ ja.2013.49.
-
(2013)
J Antibiot
-
-
Walsh, C.T.1
Wencewicz, T.A.2
-
3
-
-
84865683314
-
Thoughts and facts about antibiotics: Where we are now and where we are heading
-
J
-
Berdy J. Thoughts and facts about antibiotics: where we are now and where we are heading [J]. J Antibiot, 2012, 65: 385-395.
-
(2012)
J Antibiot
, vol.65
, pp. 385-395
-
-
Berdy, J.1
-
4
-
-
33751100882
-
Developing a new resource for drug discovery: Marine actinomycete bacteria
-
DOI 10.1038/nchembio841, PII NCHEMBIO841
-
Fenical W, Jensen PR. Developing a new resource for drug discovery: marine actinomycete bacteria [J]. Nat Chem Biol, 2006, 2: 666-673. (Pubitemid 44764208)
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.12
, pp. 666-673
-
-
Fenical, W.1
Jensen, P.R.2
-
5
-
-
77952481633
-
Novel anti-infective compounds from marine bacteria
-
J
-
Rahman H, Austin B, Mitchell W, et al. Novel anti-infective compounds from marine bacteria [J]. Mar Drugs, 2010, 8: 498-518.
-
(2010)
Mar Drugs
, vol.8
, pp. 498-518
-
-
Rahman, H.1
Austin, B.2
Mitchell, W.3
-
6
-
-
84897938888
-
Gene clusters for bioactive natural products in actinomycetes and their use in combinatorial biosynthesis
-
M Dyson P editor Norfolk: Caister Academic Press
-
Olano C, Méndez C, Salas JA. Gene clusters for bioactive natural products in actinomycetes and their use in combinatorial biosynthesis [M] // Dyson P editor. Streptomyces Molecular Biology and Biotechnology. Norfolk: Caister Academic Press, 2011.
-
(2011)
Streptomyces Molecular Biology and Biotechnology
-
-
Olano, C.1
Méndez, C.2
Salas, J.A.3
-
7
-
-
0142027815
-
Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model
-
DOI 10.1073/pnas.2034291100
-
Liu W, Ahlert J, Gao Q, et al. Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model [J]. Proc Natl Acad Sci USA, 2003, 100: 11959-11963. (Pubitemid 37271497)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.21
, pp. 11959-11963
-
-
Liu, W.1
Ahlert, J.2
Gao, Q.3
Wendt-Pienkowski, E.4
Shen, B.5
Thorson, J.S.6
-
8
-
-
34250818263
-
A genomic screening approach to the structure-guided identification of drug candidates from natural sources
-
DOI 10.1002/cbic.200600375
-
Hornung A, Bertazzo M, Dziarnowski A, et al. A genomic screening approach to the structure-guided identification of drug candidates from natural sources [J]. ChemBioChem, 2007, 8: 757-766. (Pubitemid 47183632)
-
(2007)
ChemBioChem
, vol.8
, Issue.7
, pp. 757-766
-
-
Hornung, A.1
Bertazzo, M.2
Dziarnowski, A.3
Schneider, K.4
Welzel, K.5
Wohlert, S.-E.6
Holzenkampfer, M.7
Nicholson, G.J.8
Bechthold, A.9
Sussmuth, R.D.10
Vente, A.11
Pelzer, S.12
-
9
-
-
79955563542
-
Distribution of dTDP-glucose-4,6-dehydratase gene and diversity of potential glycosylated natural products in marine sediment-derived bacteria
-
J
-
Chen F, Lin L, Wang L, et al. Distribution of dTDP-glucose-4,6- dehydratase gene and diversity of potential glycosylated natural products in marine sediment-derived bacteria [J]. Appl Microbiol Biotechnol, 2011, 90: 1347-1359.
-
(2011)
Appl Microbiol Biotechnol
, vol.90
, pp. 1347-1359
-
-
Chen, F.1
Lin, L.2
Wang, L.3
-
10
-
-
79959744432
-
Chaxamycins A -D, bioactive ansamycins from a hyper-arid desert Streptomyces sp.
-
J
-
Rateb ME, Houssen WE, Arnold M, et al. Chaxamycins A -D, bioactive ansamycins from a hyper-arid desert Streptomyces sp. [J]. J Nat Prod, 2011, 74: 1491-1499.
-
(2011)
J Nat Prod
, vol.74
, pp. 1491-1499
-
-
Rateb, M.E.1
Houssen, W.E.2
Arnold, M.3
-
11
-
-
84863614586
-
Spiroindimicins A -D: New bisindole alkaloids from a deep-sea-derived actinomycete
-
J
-
Zhang W, Liu Z, Li S, et al. Spiroindimicins A -D: new bisindole alkaloids from a deep-sea-derived actinomycete [J]. Org Lett, 2012, 14: 3364-3367.
-
(2012)
Org Lett
, vol.14
, pp. 3364-3367
-
-
Zhang, W.1
Liu, Z.2
Li, S.3
-
12
-
-
79957859264
-
Streptothricin derivatives from Streptomyces sp. I08A 1776
-
J
-
Gan ML, Zheng XD, Gan LS, et al. Streptothricin derivatives from Streptomyces sp. I08A 1776 [J]. J Nat Prod, 2011, 74: 1142-1147.
-
(2011)
J Nat Prod
, vol.74
, pp. 1142-1147
-
-
Gan, M.L.1
Zheng, X.D.2
Gan, L.S.3
-
13
-
-
84866363174
-
Two streptothricins with a cis-streptolidine lactam moiety from Streptomyces sp. I08A 1776
-
J
-
Gan ML, Guan Y, Zheng XD, et al. Two streptothricins with a cis-streptolidine lactam moiety from Streptomyces sp. I08A 1776 [J]. J Antibiot, 2012, 65: 513-516.
-
(2012)
J Antibiot
, vol.65
, pp. 513-516
-
-
Gan, M.L.1
Guan, Y.2
Zheng, X.D.3
-
14
-
-
84885060680
-
Polyketides with New Delhi metallo-β-lactamase 1 inhibitory activity from Penicillium sp.
-
J
-
Gan ML, Liu YF, Bai YL, et al. Polyketides with New Delhi metallo-β-lactamase 1 inhibitory activity from Penicillium sp. [J]. J Nat Prod, 2013, 76: 1535-1540.
-
(2013)
J Nat Prod
, vol.76
, pp. 1535-1540
-
-
Gan, M.L.1
Liu, Y.F.2
Bai, Y.L.3
-
15
-
-
60049097994
-
PCR screening of 3-amino-5-hydroxybenzoic acid synthase gene leads to identification of ansamycins and AHBA-related antibiotic producers in actinomycetes
-
J
-
Zhang HT, Wu LZ, Liu AM, et al. PCR screening of 3-amino-5-hydroxybenzoic acid synthase gene leads to identification of ansamycins and AHBA-related antibiotic producers in actinomycetes [J]. J Appl Microbiol, 2009, 106: 755-763.
-
(2009)
J Appl Microbiol
, vol.106
, pp. 755-763
-
-
Zhang, H.T.1
Wu, L.Z.2
Liu, A.M.3
-
16
-
-
19944362206
-
New PCR primers for the screening of NRPS and PKS-I systems in actinomycetes: Detection and distribution of these biosynthetic gene sequences in major taxonomic groups
-
DOI 10.1007/s00248-004-0249-6
-
Ayuso-Sacido A, Genilloud O. New PCR primers for the screening of NRPS and PKS-I systems in actinomycetes: detection and distribution of these biosynthetic gene sequences in major taxonomic groups [J]. Microb Ecol, 2005, 49: 10-24. (Pubitemid 40747800)
-
(2005)
Microbial Ecology
, vol.49
, Issue.1
, pp. 10-24
-
-
Ayuso-Sacido, A.1
Genilloud, O.2
-
17
-
-
0141511495
-
An efficient approach for screening minimal PKS genes from Streptomyces
-
DOI 10.1016/S0378-1097(99)00453-X, PII S037810979900453X
-
Metsa-Ketela M, Salo V, Halo L, et al. An efficient approach for screening minimal PKS genes from Streptomyces [J]. FEMS Microbiol Lett, 1999, 180: 1-6. (Pubitemid 29476486)
-
(1999)
FEMS Microbiology Letters
, vol.180
, Issue.1
, pp. 1-6
-
-
Metsa-Ketela, M.1
Salo, V.2
Halo, L.3
Hautala, A.4
Hakala, J.5
Mantsala, P.6
Ylihonko, K.7
-
18
-
-
79958227585
-
Genetic screening strategy for rapid access to polyether ionophore producers and products in actinomycetes
-
J
-
Wang H, Liu N, Xi L, et al. Genetic screening strategy for rapid access to polyether ionophore producers and products in actinomycetes [J]. Appl Environ Microbiol, 2011, 77: 3433-3442.
-
(2011)
Appl Environ Microbiol
, vol.77
, pp. 3433-3442
-
-
Wang, H.1
Liu, N.2
Xi, L.3
-
19
-
-
0024449599
-
Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis
-
Bibb MJ, Biro S, Motamedi H, et al. Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis [J]. EMBO J, 1989, 8: 2727-2736. (Pubitemid 19273359)
-
(1989)
EMBO Journal
, vol.8
, Issue.9
, pp. 2727-2736
-
-
Bibb, M.J.1
Biro, S.2
Motamedi, H.3
Collins, J.F.4
Hutchinson, C.R.5
-
20
-
-
42949168430
-
Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster
-
DOI 10.1099/mic.0.2007/014035-0
-
Ramos A, Lombo F, Brana AF, et al. Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster [J]. Microbiology, 2008, 154: 781-788. (Pubitemid 351736292)
-
(2008)
Microbiology
, vol.154
, Issue.3
, pp. 781-788
-
-
Ramos, A.1
Lombo, F.2
Brana, A.F.3
Rohr, J.4
Mendez, C.5
Salas, J.A.6
-
21
-
-
33748224623
-
Novel genetically engineered tetracenomycins
-
J
-
Decker H, Haag S, Udvarnoki G, et al. Novel genetically engineered tetracenomycins [J]. Angew Chem Int Ed, 1995, 34: 1107-1110.
-
(1995)
Angew Chem Int Ed
, vol.34
, pp. 1107-1110
-
-
Decker, H.1
Haag, S.2
Udvarnoki, G.3
-
22
-
-
0025103761
-
Structure-activity relationships of elloramycin and tetracenomycin C
-
Rohr J, Zeeck A. Structure-activity relationships of elloramycin and tetracenomycin C [J]. J Antibiot, 1990, 43: 1169-1178. (Pubitemid 20324380)
-
(1990)
Journal of Antibiotics
, vol.43
, Issue.9
, pp. 1169-1178
-
-
Rohr, J.1
Zeeck, A.2
-
23
-
-
0032556233
-
Novel hybrid tetracenomycins through combinatorial biosynthesis using a glycosyltransferase encoded by the elm genes in cosmid 16F4 and which shows a broad sugar substrate specificity
-
DOI 10.1021/ja981687e
-
Wohlert SE, Blanco G, Lombó F, et al. Novel hybrid tetracenomycins through combinatorial biosynthesis using a glycosyltransferase encoded by the elm genes in cosmid 16F4 and which shows a broad sugar substrate specificity [J]. J Am Chem Soc, 1998, 120: 10596-10601. (Pubitemid 28498802)
-
(1998)
Journal of the American Chemical Society
, vol.120
, Issue.41
, pp. 10596-10601
-
-
Wohlert, S.-E.1
Blanco, G.2
Lombo, F.3
Fernandez, E.4
Brana, A.F.5
Reich, S.6
Udvarnoki, G.7
Mendez, C.8
Decker, H.9
Frevert, J.10
Salas, J.A.11
Rohr, J.12
-
24
-
-
0024515634
-
Oxidation processes in the biosynthesis of the tetracenomycin and elloramycin antibiotics
-
Anderson MG, Khoo CL, Rickards RW. Oxidation processes in the biosynthesis of the tetracenomycin and elloramycin antibiotics [J]. J Antibiot, 1989, 42: 640-643. (Pubitemid 19119110)
-
(1989)
Journal of Antibiotics
, vol.42
, Issue.4
, pp. 640-643
-
-
Anderson, M.G.1
Khoo, C.L.-Y.2
Rickards, R.W.3
-
25
-
-
0020670070
-
Studies of tomaymycin I. The structure determination of tomaymycin on the basis of NMR spectra
-
Tozuka Z, Takaya T. Studies on tomaymycin. I. The structure determination of tomaymycin on the basis of NMR spectra [J]. J Antibiot, 1983, 36: 142-146. (Pubitemid 13148120)
-
(1983)
Journal of Antibiotics
, vol.36
, Issue.2
, pp. 142-146
-
-
Tozuka, Z.1
Takaya, T.2
-
26
-
-
84943116073
-
The sructure of tomaymycin and oxotomamycin
-
J
-
Kariyone K, Yazawa H, Kohsaka M. The sructure of tomaymycin and oxotomamycin [J]. Chem Pharm Bull, 1971, 11: 2289-2293.
-
(1971)
Chem Pharm Bull
, vol.11
, pp. 2289-2293
-
-
Kariyone, K.1
Yazawa, H.2
Kohsaka, M.3
-
27
-
-
0018427014
-
STOFFWECHSELPRODUKTE VON MIKROORGANISMEN. 175. MITTEILUNG. TETRACENOMYCIN C
-
DOI 10.1007/BF00689973
-
Weber W, Zähner H, Siebers J, et al. Metabolic products of microorganisms. 175. Tetracenomycin C [J]. Arch Microbiol, 1979, 121: 111-116. (Pubitemid 9233775)
-
(1979)
Archives of Microbiology
, vol.121
, Issue.2
, pp. 111-116
-
-
Weber, W.1
Zaehner, H.2
Siebers, J.3
-
28
-
-
25144442113
-
Tetracenomycins - New antibiotics from Streptomyces glaucescens
-
C Schaal, K. P. and Pulverer, G (eds.) Stuttgart: Gustav Fischer Verlag
-
Weber W, Zahner H, Siebers J, et al. Tetracenomycins - new antibiotics from Streptomyces glaucescens [C] // Schaal, K. P. and Pulverer, G (eds.). Actinomycetes: Proceedings of the Fourth International Symposium on Actinomycete Biology. Stuttgart: Gustav Fischer Verlag, 1981: 465-468.
-
(1981)
Actinomycetes: Proceedings of the Fourth International Symposium on Actinomycete Biology
, pp. 465-468
-
-
Weber, W.1
Zahner, H.2
Siebers, J.3
-
29
-
-
0022361388
-
Metabolic products of microorganisms. 225 Elloramycin, a new anthracycline-like antibiotic from Streptomyces olivaceus. Isolation, characterization, structure and biological properties
-
Drautz H, Reuschenbach P, Zahner H, et al. Metabolic products of microorganisms. 225. Elloramycin, a new anthracycline-like antibiotic from Streptomyces olivaceus. Isolation, characterization, structure and biological properties [J]. J Antibiot, 1985, 38: 1291-1301. (Pubitemid 16206700)
-
(1985)
Journal of Antibiotics
, vol.38
, Issue.10
, pp. 1291-1301
-
-
Drautz, H.1
Reuschenbach, P.2
Zahner, H.3
-
30
-
-
0032860405
-
Tolerance and specificity of polyketide synthases
-
DOI 10.1146/annurev.biochem.68.1.219
-
Khosla C, Gokhale RS, Jacobsen JR, et al. Tolerance and specificity of polyketide synthases [J]. Annu Rev Biochem, 1999, 68: 219-253. (Pubitemid 29449192)
-
(1999)
Annual Review of Biochemistry
, vol.68
, pp. 219-253
-
-
Khosla, C.1
Gokhale, R.S.2
Jacobsen, J.R.3
Cane, D.E.4
|