Overexpression of lncRNA H19 enhances carcinogenesis and metastasis of gastric cancer

Oncotarget

Volumn 5, Issue 8, 2014, Pages 2318-2329

  Li, Hao ^a   Yu, Beiqin ^a   Li, Jianfang ^a   Su, Liping ^a   Yan, Min ^a   Zhu, Zhenggang ^a   Liu, Bingya ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Gastric cancer; H19; Long non coding RNA; MicroRNA; MiR 675

Indexed keywords

LONG UNTRANSLATED RNA; MICRORNA; MICRORNA 675; RNA H19; UNCLASSIFIED DRUG; CALMODULIN; CALN1 PROTEIN, HUMAN; H19 LONG NON-CODING RNA;

ANIMAL CELL; ARTICLE; CALN1 GENE; CANCER CELL; CARCINOGENESIS; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE FUNCTION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; LNCRNA H19 GENE; MAJOR CLINICAL STUDY; MALE; METASTASIS; MOUSE; NONHUMAN; ONCOGENE; PROTEIN BINDING; STOMACH CANCER; UPREGULATION; AGED; ANIMAL; BIOSYNTHESIS; CELL MOTION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; IMMUNOPRECIPITATION; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; NUDE MOUSE; PATHOLOGY; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH TUMOR; TUMOR CELL LINE; TUMOR INVASION; WESTERN BLOTTING; XENOGRAFT;

AGED; ANIMALS; BLOTTING, WESTERN; CALMODULIN; CARCINOGENESIS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HETEROGRAFTS; HUMANS; IMMUNOPRECIPITATION; KAPLAN-MEIER ESTIMATE; MALE; MICE; MICE, NUDE; MICRORNAS; MIDDLE AGED; NEOPLASM INVASIVENESS; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, LONG NONCODING; STOMACH NEOPLASMS; UP-REGULATION;

EID: 84899552234     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1913     Document Type: Article

References (25)

1. International Agency for Research on Cancer (IARC). GLOBOCAN2008 Database 2010.
2. ENCODE Project Consortium. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 2007,14;447(7146):799-816.
3. FANTOM Consortium; RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group). The transcriptional landscape of the mammalian genome. Science. 2005,2;309(5740):1559-63.
4. Johnson JM, Edwards S, Shoemaker D, Schadt EE. Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments.Trends Genet. 2005;21(2):93-102.
5. Furuno M, Pang KC, Ninomiya N, Fukuda S, Frith MC, Bult C, Kai C, Kawai J, Carninci P, Hayashizaki Y, Mattick JS, Suzuki H. Clusters of internally primed transcripts reveal novel long noncoding RNAs. PLoS Genet. 2006;2(4):e37.
6. Matouk IJ, DeGroot N, Mezan S, Ayesh S, Abulail R, Hochberg A, Galun E. The H19 non-coding RNA is essential for human tumor growth. PLoS One. 2007;2(9):e845.
7. Whitehead J, Pandey GK, Kanduri C. Regulation of the mammalian epigenome by long noncoding RNAs. BiochimBiophysActa. 2009;1790(9):936-47.
8. Li L, Feng T, Lian Y, Zhang G, Garen A, Song X. Role of human noncoding RNAs in the control of tumorigenesis. ProcNatlAcadSci U S A. 2009;106(31):12956-61.
9. Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, van de Vijver MJ, Sukumar S, Chang HY. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 2010;464(7291):1071-6.
10. Gutschner T, Hämmerle M, Eissmann M, Hsu J, Kim Y, Hung G, Revenko A, Arun G, Stentrup M, Gross M, Zörnig M, MacLeod AR, Spector DL, Diederichs S. The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Res. 2013;73(3):1180-9.
11. Poirier F, Chan CT, Timmons PM, Robertson EJ, Evans MJ, Rigby PW. The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo. Development. 1991;113(4):1105-14.
12. Tabano S, Colapietro P, Cetin I, Grati FR, Zanutto S, Mandò C, Antonazzo P, Pileri P, Rossella F, Larizza L, Sirchia SM, Miozzo M. Epigenetic modulation of the IGF2/H19 imprinted domain in human embryonic and extra-embryonic compartments and its possible role in fetal growth restriction. Epigenetics. 2010;5(4):313-24.
13. Berteaux N, Lottin S, Monté D, Pinte S, Quatannens B, Coll J, Hondermarck H, Curgy JJ, Dugimont T, Adriaenssens E. H19 mRNA-like noncoding RNA promotes breast cancer cell proliferation through positive control by E2F1. J Biol Chem. 2005;280(33):29625-36.
14. Berteaux N, Aptel N, Cathala G, Genton C, Coll J, Daccache A, Spruyt N, Hondermarck H, Dugimont T, Curgy JJ, Forné T, Adriaenssens E. A novel H19 antisense RNA overexpressed in breast cancer contributes to paternal IGF2 expression. Mol Cell Biol. 2008;28(22):6731-45.
15. Byun HM, Wong HL, Birnstein EA, Wolff EM, Liang G, Yang AS. Examination of IGF2 and H19 loss of imprinting in bladder cancer. Cancer Res. 2007;67(22):10753-8.
16. Luo M, Li Z, Wang W, Zeng Y, Liu Z, Qiu J. Upregulated H19 contributes to bladder cancer cell proliferation by regulating ID2 expression. FEBS J. 2013;280(7):1709-16.
17. Kim SJ, Park SE, Lee C, Lee SY, Jo JH, Kim JM, Oh YK. Alterations in promoter usage and expression levels of insulin-like growth factor-II and H19 genes in cervical carcinoma exhibiting biallelic expression of IGF-II. BiochimBiophysActa. 2002;1586(3):307-15.
18. Cai X, Cullen BR. The imprinted H19 noncoding RNA is a primary microRNA precursor. RNA. 2007;13(3):313-6.
19. Gao WL, Liu M, Yang Y, Yang H, Liao Q, Bai Y, Li YX, Li D, Peng C, Wang YL. The imprinted H19 gene regulates human placental trophoblast cell proliferation via encoding miR-675 that targets Nodal Modulator 1 (NOMO1). RNA Biol. 2012;9(7):1002-10.
20. Tsang WP, Ng EK, Ng SS, Jin H, Yu J, Sung JJ, Kwok TT. Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis. 2010;31(3):350-8.
21. Kim KI, van de Wiel MA. Effects of dependence in high-dimensional multiple testing problems. BMC Bioinformatics. 2008;9:114.
22. Noble WS. How does multiple testing correction work? Nat Biotechnol. 2009;27(12):1135-7.
23. Ponting CP, Oliver PL, Reik W. Evolution and functions of long noncoding RNAs. Cell. 2009;136(4):629-41.
24. Wang KC, Chang HY. Molecular mechanisms of long noncoding RNAs. Mol Cell. 2011;43(6):904-14.
25. Tsang WP, Kwok TT. Riboregulator H19 induction of MDR1-associated drug resistance in human hepatocellular carcinoma cells. Oncogene. 2007;26(33):4877-81.