Synthesis and biological evaluation of novel 2-methoxypyridylamino- substituted riminophenazine derivatives as antituberculosis agents

Molecules

Volumn 19, Issue 4, 2014, Pages 4380-4394

  Zhang, Dongfeng ^a   Liu, Yang ^a   Zhang, Chunlin ^a   Zhang, Hao ^a   Wang, Bin ^b   Xu, Jian ^b   Fu, Lei ^b   Yin, Dali ^a   Cooper, Christopher B ^c   Ma, Zhenkun ^c   Lu, Yu ^b   Huang, Haihong ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT   (United States)

Author keywords

2 methoxypyridylamino substituted riminophenazines; Antituberculosis activity; Clofazimine; Skin discoloration

Indexed keywords

AMINOPYRIDINE DERIVATIVE; CLOFAZIMINE; TUBERCULOSTATIC AGENT;

ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; HALF LIFE TIME; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; ORAL DRUG ADMINISTRATION; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUBERCULOSIS;

ADMINISTRATION, ORAL; AMINOPYRIDINES; ANIMALS; ANTITUBERCULAR AGENTS; CLOFAZIMINE; DRUG DESIGN; HALF-LIFE; MICE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE-ACTIVITY RELATIONSHIP; TUBERCULOSIS;

EID: 84899548688     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules19044380     Document Type: Article

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