The micronutrient supplements, zinc sulphate and folic acid, did not ameliorate sperm functional parameters in oligoasthenoteratozoospermic men

Andrologia

Volumn 46, Issue 9, 2014, Pages 956-962

  Raigani, M ^a,b   Yaghmaei, B ^b   Amirjannti, N ^a   Lakpour, N ^a   Akhondi, M M ^a   Zeraati, H ^c   Hajihosseinal, M ^a   Sadeghi, M R ^a  

^a AVICENNA RESEARCH INSTITUTE   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Folic acid; Male infertility; Oligoasthenoteratozoospermia; Sperm parameters; Zinc sulphate

Indexed keywords

ACRIDINE ORANGE; ANILINE; CHROMOMYCIN A3; CYANOCOBALAMIN; FOLIC ACID; MALONALDEHYDE; PLACEBO; TOLONIUM CHLORIDE; ZINC SULFATE; ANTIOXIDANT; CHROMATIN; TRACE ELEMENT;

ANTIOXIDANT ASSAY; ARTICLE; BLOOD SAMPLING; CHROMATIN; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; FOLIC ACID BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; NUTRITIONAL PARAMETERS; OLIGOASTHENOTERATOZOOSPERMIA; RANDOMIZED CONTROLLED TRIAL; SEMEN ABNORMALITY; SPERM QUALITY; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; STAINING; TREATMENT DURATION; VITAMIN SUPPLEMENTATION; ZINC BLOOD LEVEL; ASTHENOZOOSPERMIA; CONGENITAL MALFORMATION; DIET SUPPLEMENTATION; DRUG EFFECTS; METABOLISM; OLIGOSPERMIA; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPERMATOZOON; SPERMATOZOON COUNT;

ANTIOXIDANTS; ASTHENOZOOSPERMIA; CHROMATIN; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FOLIC ACID; HUMANS; MALE; MALONDIALDEHYDE; MICRONUTRIENTS; OLIGOSPERMIA; SPERM COUNT; SPERM MOTILITY; SPERMATOZOA; ZINC SULFATE;

EID: 84899547167     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/and.12180     Document Type: Article

References (27)

1. Agarwal A, Sekhon LH (2010) The role of antioxidant therapy in the treatment of male infertility. Hum Fertil (Camb) 13:217-225.
2. Aitken RJ (2006) Sperm function tests and fertility. Int J Androl 29:69-75.
3. Bjorndahl L, Soderlund I, Kvist U (2003) Evaluation of the one-step eosin-nigrosin staining technique for human sperm vitality assessment. Hum Reprod 18:813-816.
4. Chimienti F, Aouffen M, Favier A, Seve M (2003) Zinc homeostasis regulating proteins: new drug targets for triggering cell fate. Curr Drug Targets 4:323-338.
5. Comhaire FH (1987) Towards more objectivity in diagnosis and management of male infertility. Int J Androl 7:1-53.
6. De Kretser DM (1997) Male infertility. Lancet 349:787-790.
7. Draper HH, Hadley M (1990) Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 186:421-431.
8. Ebisch IM, Pierik FH, De Jong FH, Thomas CM, Steegers-Theunissen RP (2006) Does folic acid and zinc sulphate intervention affect endocrine parameters and sperm characteristics in men? Int J Androl 29:339-345.
9. Erel O (2004) A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem 37:277-285.
10. Favier AE (1992) The role of zinc in reproduction. Hormonal mechanisms. Biol Trace Elem Res 32:363-382.
11. Favier M, Faure P, Roussel AM, Coudray C, Blache D, Favier A (1993) Zinc deficiency and dietary folate metabolism in pregnant rats. J Trace Elem Electrolytes Health Dis 7:19-24.
12. Franken DR, Oehninger S (2012) Semen analysis and sperm function testing. Asian J Androl 14:6-13.
13. Huang YL, Tseng WC, Cheng SY, Lin TH (2000) Trace elements and lipid peroxidation in human seminal plasma. Biol Trace Elem Res 76:207-215.
14. Hamdi SA, Nassif OI, Ardawi MS (1997) Effect of marginal or severe dietary zinc deficiency on testicular development and functions of the rat. Arch Androl 38:243-253.
15. Lakpour N, Reda ZM, Akhondi MM, Agarwal A, Kharrazi H, Zeraati H, Amirjannati N, Sadeghi MR (2012) Relationship of seminal plasma antioxidants and serum male hormones with sperm chromatin status in male factor infertility. Syst Biol Reprod Med 58:236-244.
16. Lakpour N, Mirfeizollahi A, Farivar S, Akhondi MM, Hashemi SB, Amirjannati N, Heidari-Vala H, Sadeghi MR (2013) The association of seminal plasma antioxidant levels and sperm chromatin status with genetic variants of GSTM1 and GSTP1(Ile105Val and Ala114Val) in infertile men with oligoasthenoteratozoospermia. Dis Markers 34:205-210.
17. Landau B, Singer R, Klein T, Segenreich E (1978) Folic acid levels in blood and seminal plasma of normo- and oligospermic patients prior and following folic acid treatment. Experientia 34:1301-1302.
18. Madding CI, Jacob M, Ramsay VP, Sokol RZ (1986) Serum and semen zinc levels in normozoospermic and oligozoospermic men. Ann Nutr Metab 30:213-218.
19. Murphy LE, Mills JL, Molloy AM, Qian C, Carter TC, Strevens H, Wide-Swensson D, Giwercman A, Levine RJ (2011) Folate and vitamin B12 in idiopathic male infertility. Asian J Androl 13:856-861.
20. Naber THJ, van den Hamer CJA, Baadenhuysen H, Jansen JBMJ (1998) The value of methods to determine zinc deficiency in patients with Crohn's disease. Scand J Gastroenterol 33:514-523.
21. Omu AE, Al-Qattan F, Abdulhadi F, Fernandes S (1999) Seminal immune response in infertile men with leukocytospermia: effect on antioxidant activity. Eur J Obstet Gynecol Reprod Biol 86:195-202.
22. Sadeghi MR, Hodjat M, Lakpour N, Arefi S, Amirjannati N, Modarresi T, Hossaini Jadda H, Akhondi MM (2009) Effects of sperm chromatin integrity on fertilization rate and embryo quality following intracytoplasmic sperm injection. Avicenna J Med Biotech 1:173-180.
23. Sadeghi MR, Lakpour N, Heidari-Vala H, Hodjat M, Amirjannati N, Hossaini Jadda H, Binaafar S, Akhondi MM (2011) Relationship between sperm chromatin status and ICSI outcome in men with obstructive azoospermia and unexplained infertile normozoospermia. Rom J Morphol Embryol 52:645-651.
24. Swayne BG, Kawata A, Behan NA, Williams A, Wade MG, Macfarlane AJ, Yauk CL (2012) Investigating the effects of dietary folic acid on sperm count, DNA damage and mutation in Balb/c mice. Mutat Res 737:1-7.
25. Wong WY, Thomas CM, Merkus JM, Zielhuis GA, Steegers-Theunissen RP (2000) Male factor subfertility: possible causes and the impact of nutritional factors. Fertil Steril 73:435-442.
26. Wong WY, Merkus HM, Thomas CM, Menkveld R, Zielhuis GA, Steegers-Theunissen RP (2002) Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial. Fertil Steril 77:491-498.
27. World Health Organization (WHO) (1999) Manual for the Standardized Investigation, Diagnosis and Management of the Infertile Male, 1st edn. Cambridge University Press, New York, NY.