Association of the novel aminoglycoside resistance determinant RmtF with NDM carbapenemase in enterobacteriaceae isolated in India and the UK

Journal of Antimicrobial Chemotherapy

Volumn 68, Issue 7, 2013, Pages 1543-1550

  Hidalgo, Laura ^a   Hopkins, Katie L ^b   Gutierrez, Belen ^a   Ovejero, Cristina M ^a   Shukla, Suruchi ^c   Douthwaite, Stephen ^d   Prasad, Kashi N ^c   Woodford, Neil ^b   Gonzalez Zorn, Bruno ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

^c SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

16S rRNA methyltransferases; antimicrobial; Resistance

Indexed keywords

AMIKACIN; BACTERIAL ENZYME; CARBAPENEMASE; GENTAMICIN; METHYLTRANSFERASE; NDM CARBAPENEMASE; RMTF ENZYME; RNA 16S; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENETICS; BACTERIUM ISOLATION; CITROBACTER FREUNDII; ELECTROPORATION; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE; ESCHERICHIA COLI; GENETIC SCREENING; GENETIC SIMILARITY; HUMAN; INDIA; KLEBSIELLA PNEUMONIAE; METHYLATION; MULTILOCUS SEQUENCE TYPING; NONHUMAN; POLYMERASE CHAIN REACTION; UNITED KINGDOM;

EID: 84879483942     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt078     Document Type: Article

References (35)

1. WHO. Critically Important Antimicrobials for Human Medicine: Categorization for the Development of Risk Management Strategies to Contain Antimicrobial Resistance Due to Non-Human Antimicrobial Use: Report of the SecondWHO Expert Meeting, Copenhagen, 29-31 May 2007. http://www.who.int/foodborne_disease/resistance/antimicrobials_ human.pdf (10 Oct 2011, date last accessed).
2. Davies J, Wright GD. Bacterial resistance to aminoglycoside antibiotics. Trends Microbiol 1997; 5: 234-40.
3. Galimand M, Courvalin P, Lambert T. Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation. Antimicrob Agents Chemother 2003; 47: 2565-71.
4. Wachino J, Arakawa Y. Exogenously acquired 16S rRNA methyltransferases found in aminoglycoside-resistant pathogenic Gram-negative bacteria: an update. Drug Resist Updat 2012; 15: 133-48.
5. Galimand M, Courvalin P, Lambert T. RmtF, a new member of the aminoglycoside resistance 16S rRNA N7 G1405 methyltransferase family. Antimicrob Agents Chemother 2012; 56: 3960-2.
6. Hidalgo L, Hopkins KL, San Millan A et al. Discovery of a new 16S rRNA methylase, RmtF, conferring high-level aminoglycoside resistance in human Enterobacteriaceae isolates from India. Clin Microbiol Infect 2012; 18 Suppl S3: 313 (P1243).
7. Jiang Y, Yu D, Wei Z, et al. Complete nucleotide sequence of Klebsiella pneumoniae multidrug resistance plasmid pKP048, carrying blaKPC-2,blaDHA-1, qnrB4, and armA. Antimicrob Agents Chemother 2010; 54: 3967-9.
8. Yan JJ, Wu JJ, Ko WC, et al. Plasmid-mediated 16S rRNA methylases conferring high-level aminoglycoside resistance in Escherichia coli and Klebsiella pneumoniae isolates from two Taiwanese hospitals. J Antimicrob Chemother 2004; 54: 1007-12.
9. Hidalgo L, Hopkins KL, Wareham DW, et al. Association of extended spectrum b-lactamase VEB-5 and 16S rRNA methyltransferase ArmA in Salmonella enterica from United Kingdom. Antimicrob Agents Chemother 2012; 56: 4985-7.
10. Lee HW, Kang HY, Shin KS, et al. Multidrug-resistant Providencia isolates carrying blaPER-1, blaVIM-2, and armA. J Microbiol 2007; 45: 272-4.
11. Yong D, Toleman MA, Giske CG, et al. Characterization of a new metallo-b-lactamase gene, blaNDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob Agents Chemother 2009; 53: 5046-54.
12. Kumarasamy KK, Toleman MA, Walsh TR, et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis 2010; 10: 597-602.
13. Poirel L, Revathi G, Bernabeu S, et al. Detection of NDM-1-producing Klebsiella pneumoniae in Kenya. Antimicrob Agents Chemother 2010; 55: 934-6.
14. Kumarasamy KK, Thirunarayan MA, Padma K. Coexistence of blaOXA-23 with blaNDM-1 and armA in clinical isolates of Acinetobacter baumannii from India. J Antimicrob Chemother 2010; 65: 2253-70.
15. Ho PL, Lo WU, Yeung MK, et al. Complete sequencing of pNDM-HK encoding NDM-1 carbapenemase from a multidrug-resistant Escherichia coli strain isolated in Hong Kong. PLoS One 2011; 6: e17989.
16. Granier S, Hidalgo L, San Millan A, et al. ArmA methyltransferase in a monophasic Salmonella enterica isolated from food. Antimicrob Agents Chemother 2011; 55: 5262-6.
17. Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis 2007; 45: 88-94.
18. Davis MA, Baker KN, Orfe LH, et al. Discovery of a gene conferring multiple-aminoglycoside resistance in Escherichia coli. Antimicrob Agents Chemother 2010; 54: 2666-9.
19. Batchelor M, Hopkins K, Threlfall EJ, et al. blaCTX-M genes in clinical Salmonella isolates recovered from humans in England and Wales from 1992 to 2003. Antimicrob Agents Chemother 2005; 49: 1319-22.
20. Pérez-Pérez FJ, Hanson ND. Detection of plasmid-mediated AmpC b-lactamase genes in clinical isolates by using multiplex PCR. J Clin Microbiol 2002; 40: 2153-62.
21. Clermont O, Bonacorsi S, Bingen E. Rapid and simple determination of the Escherichia coli phylogenetic group. Appl Environ Microbiol 2000; 66: 4555-8.
22. García-Fernández A, Villa L, Moodley A, et al. Multilocus sequence typing of IncN plasmids. J Antimicrob Chemother 2011; 66: 1987-91.
23. Douthwaite S, Kirpekar F. Identifying modifications in RNA by MALDI mass spectrometry. Methods Enzymol 2007; 425: 1-20.
24. Gutierrez B, Escudero JA, San Millan A, et al. Fitness cost and interference of Arm/Rmt aminoglycoside resistance with the RsmF housekeeping methyltransferases. Antimicrob Agents Chemother 2012; 56: 2335-41.
25. Andersen TE, Porse BT, Kirpekar F. A novel partial modification at C2501 in Escherichia coli 23S ribosomal RNA. RNA 2004; 10: 907-13.
26. Kirpekar F, Douthwaite S, Roepstorff P. Mapping posttranscriptional modifications in 5S ribosomal RNA by MALDI mass spectrometry. RNA 2000; 6: 296-306.
27. Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995; 33: 2233-9.
28. Livermore DM, Warner M, Mushtaq S. What remains against carbapenem-resistant Enterobacteriaceae? Evaluation of chloramphenicol, ciprofloxacin, colistin, fosfomycin, minocycline, nitrofurantoin, temocillin and tigecycline. Int J Antimicrob Agents 2011; 37: 415-9.
29. Cundliffe E. How antibiotic-producing organisms avoid suicide. Annu Rev Microbiol 1989; 43: 207-33.
30. Deng Y, He L, Chen S, et al. F33:A-:B- and F2:A-:B- plasmids mediate dissemination of rmtB-blaCTX-M-9 group genes and rmtB-qepA in Enterobacteriaceae isolates from pets in China. Antimicrob Agents Chemother 2011; 55: 4926-9.
31. Gonzalez-Zorn B, Teshager T, Casas M, et al. armA and aminoglycoside resistance in Escherichia coli. Emerg Infect Dis, 2005; 11: 954-6.
32. Hopkins KL, Escudero JA, Hidalgo L, et al. 16S rRNA methyltransferase RmtC in Salmonella enterica serovar Virchow. Emerg Infect Dis 2010; 16: 712-5.
33. Stone NR,Woodford N, Livermore DM, et al. Breakthrough bacteraemia due to tigecycline-resistant Escherichia coli with New Delhi metallo-b-lactamase (NDM)-1 successfully treated with colistin in a patient with calciphylaxis. J Antimicrob Chemother 2011; 66: 2677-8.
34. Dunkle JA, Wang L, Feldman MB, et al. Structures of the bacterial ribosome in classical and hybrid states of tRNA binding. Science 2011; 332: 981-4.
35. Andersen NM, Douthwaite S. YebU is a m5C methyltransferase specific for 16S rRNA nucleotide 1407. J Mol Biol 2006; 359: 777-86.