Rapid detection of β-lactamase-hydrolyzing extended-spectrum cephalosporins in Enterobacteriaceae by use of the new chromogenic βLacta test

Journal of Clinical Microbiology

Volumn 52, Issue 5, 2014, Pages 1741-1744

  Morosini, María Isabel ^a,b   García Castillo, María ^a,b   Tato, Marta ^a,b   Gijón, Desirèe ^a,b   Valverde, Aránzazu ^a,c   Ruiz Garbajosa, Patricia ^a,b   Cantón, Rafael ^a,b,d  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b Red Española de Investigación en Patología Infecciosa REIPI   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CEPHALOSPORIN; EXTENDED SPECTRUM BETA LACTAMASE; BACTERIAL PROTEIN; BETA LACTAMASE; CARBAPENEMASE; CEPHALOSPORIN DERIVATIVE;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM DETECTION; BACTERIUM ISOLATE; CITROBACTER FREUNDII; CONTROLLED STUDY; ENTEROBACTER; ENTEROBACTERIACEAE; ENZYME ASSAY; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; MORGANELLA MORGANII; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEUS MIRABILIS; PROVIDENCIA STUARTII; SERRATIA MARCESCENS; DRUG EFFECTS; ENTEROBACTERIACEAE INFECTIONS; GENETICS; HYDROLYSIS; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; PROCEDURES;

BACTERIAL PROTEINS; BETA-LACTAMASES; CEPHALOSPORINS; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; HYDROLYSIS; MICROBIAL SENSITIVITY TESTS;

EID: 84899519397     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.03614-13     Document Type: Article

References (20)

1. Laxminarayan R, Duse A, Wattal C, Zaidi AK, Wertheim HF, Sumpradit N, Vlieghe E, Hara GL, Gould IM, Goossens H, Greko C, So AD, Bigdeli M, Tomson G, Woodhouse W, Ombaka E, Peralta AQ, Qamar FN, Mir F, Kariuki S, Bhutta ZA, Coates A, Bergstrom R, Wright GD, Brown ED, Cars O. 2013. Antibiotic resistance: the need for global solutions. Lancet Infect. Dis. 13:1057-1098. http://dx.doi.org/10.1016/S1473-3099 (13) 70318-9.
2. Rice LB. 2009. The clinical consequences of antimicrobial resistance. Curr. Opin. Microbiol. 12:476-481. http://dx.doi.org/10.1016/j.mib.2009.08.001.
3. Livermore DM, Andrews JM, Hawkey PM, Ho PL, Keness Y, Doi Y, Paterson D, Woodford N. 2012. Are susceptibility tests enough, or should laboratories still seek ESBLs and carbapenemases directly? J. Antimicrob. Chemother. 67:1569-1577. http://dx.doi.org/10.1093/jac/dks088.
4. Thomson KS. 2010. Extended-spectrum-|3-lactamase, AmpC, and carbapenemase issues. J. Clin. Microbiol. 48:1019-1025. http://dx.doi.org/10.1128/JCM.00219- 10.
5. Naas T, Cuzon G, Truong H, Bernabeu S, Nordmann P. 2010. Evaluation of a DNA microarray, the Check-Points ESBL/KPC array, for rapid detection of TEM, SHV, and CTX-M extended-spectrum β-lactamases and KPC carbapenemases. Antimicrob. Agents Chemother. 54:3086-3092. http://dx.doi.org/10.1128/AAC.01298- 09.
6. Ellem J, Partridge SR, Iredell JR. 2011. Efficient direct extendedspectrum (3-lactamase detection by multiplex real-time PCR: accurate assignment of phenotype by use of a limited set of genetic markers. J. Clin. Microbiol. 49:3074-3077. http://dx.doi.org/10.1128/JCM.02647-10.
7. Sparbier K, Schubert S, Weller U, Boogen C, Kostrzewa M. 2012. Matrix-assisted laser desorption ionization-time of flight mass spectrometry-based functional assay for rapid detection of resistance against (3-lactam antibiotics. J. Clin. Microbiol. 50:927-937. http://dx.doi.org/10. 1128/JCM.05737-11.
8. Nordmann P, Dortet L, Poirel L. 2012. Rapid detection of extendedspectrum-β-lactamase-producing Enterobacteriaceae. J. Clin. Microbiol. 50:3016-3022. http://dx.doi.org/10.1128/JCM.00859-12.
9. Hanaki H, Kubo R, Nakano T, Kurihara M, Sunagawa K. 2004. Characterization of HMRZ-86: a novel chromogenic cephalosporin for the detection of extended-spectrum β-lactamases. J. Antimicrob. Chemother. 53:888-889. http://dx.doi.org/10.1093/jac/dkh166.
10. Hanaki H, Koide Y, Yamazaki H, Kubo R, Nakano T, Atsuda K, Sunakawa K. 2007. Substrate specificity of HMRZ-86 for [3-lactamases, including extended-spectrum β-lactamases (ESBLs). J. Infect. Chemother. 13:390-395. http://dx.doi.org/10.1007/s10156-007-0563-2.
11. Renvoisé A, Decré D, Amarsy-Guerle R, Huang TD, Jost C, Podglajen I, Raskine L, Genel N, Bogaerts P, Jarlier V, Arlet G. 2013. Evaluation of the βLacta test, a rapid test detecting resistance to third-generation cephalosporins in clinical strains of Enterobacteriaceae. J. Clin. Microbiol. 51:4012-4017. http://dx.doi.org/10.1128/JCM.01936-13.
12. Morosini MI, García-Castillo M, Coque TM, Valverde A, Novais A, Loza E, Baquero F, Cantón R. 2006. Antibiotic coresistance in extendedspectrum-[3-lactamase-producing Enterobacteriaceae and in vitro activity of tigecycline. Antimicrob. Agents Chemother. 50:2695-2699. http://dx.doi.org/10.1128/AAC.00155-06.
13. Tato M, Coque TM, Ruíz-Garbajosa P, Pintado V, Cobo J, Sader HS, Jones RN, Baquero F, Cantón R. 2007. Complex clonal and plasmid epidemiology in the first outbreak of Enterobacteriaceae infection involving VIM-1 metallo-[3-lactamase in Spain: toward endemicity? Clin. Infect. Dis. 45:1171-1178. http://dx.doi.org/10.1086/522288.
14. Curiao T, Morosini MI, Ruiz-Garbajosa P, Robustillo A, Baquero F, Coque TM, Cantón R. 2010. Emergence of blaKPC-3-Tn4401a associated with a pKPN3/4-like plasmid within ST384 and ST388 Klebsiella pneumoniae clones in Spain. J. Antimicrob. Chemother. 65:1608-1614. http://dx.doi.org/10.1093/jac/ dkq174.
15. Ruiz-Garbajosa P, Curiao T, Tato M, Gijón D, Pintado V, Valverde A, Baquero F, Morosini MI, Coque TM, Cantón R. 2013. Multiclonal dispersal of KPC genes following the emergence of non-ST258 KPC-producing Klebsiella pneumoniae clones in Madrid, Spain. J. Antimicrob. Chemother. 68:2487-2492. http://dx.doi.org/10.1093/jac/dkt237.
16. European Committee on Antimicrobial Susceptibility Testing. 2013. Breakpoint tables for interpretation of MICs and zone diameters, version 3.1. http://www.eucast.org/fileadmin/src/media/PDFs/EUCAST-files/Breakpoint-tables/ Breakpoint-table-v-3.1.pdf
17. Giske CG, Gezelius L, Samuelsen Ø, Warner M, Sundsfjord A, Woodford N. 2011. A sensitive and specific phenotypic assay for detection of metallo-[3-lactamases and KPC in Klebsiella pneumoniae with the use of meropenem disks supplemented with aminophenylboronic acid, dipicolinic acid and cloxacillin. Clin. Microbiol. Infect. 17:552-556. http://dx.doi.org/10.1111/j. 1469-0691.2010.03294.x.
18. Bush K. 1989. Excitement in the β-lactamase arena. J. Antimicrob. Chemother. 24:831-836. http://dx.doi.org/10.1093/jac/24.6.831.
19. Li M, Conklin BC, Taracila MA, Hutton RA, Skalweit MJ. 2012. Substitutions at position 105 in SHV family β-lactamases decrease catalytic efficiency and cause inhibitor resistance. Antimicrob. Agents Chemother. 56:5678-5686. http://dx.doi.org/10.1128/AAC.00711-12.
20. Poirel L, Potron A, Nordmann P. 2012. OXA-48-like carbapenemases: the phantom menace. J. Antimicrob. Chemother. 67:1597-1606. http://dx.doi.org/10. 1093/jac/dks121.