Blood concentration of copper, cadmium, zinc and lead in horses and its relation to hematological and biochemical parameters

Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering

Volumn 49, Issue 8, 2014, Pages 973-979

  Massanyi, Peter ^a,b   Stawarz, Robert ^b   Halo, Marko ^a   Formicki, Grzegorz ^b   Lukac, Norbert ^a   Cupka, Peter ^a   Schwarcz, Pavol ^a   Kovacik, Anton ^a   Tusimova, Eva ^a   Kovacik, Jaroslav ^a  

^a SLOVAK UNIVERSITY OF AGRICULTURE IN NITRA   (Slovakia)

^b PEDAGOGICAL UNIVERSITY   (Poland)

Author keywords

Biochemistry; Blood; Cadmium; Copper; Hematology; Horse; Lead; Zinc

Indexed keywords

BIOCHEMISTRY; CADMIUM; COPPER; HEALTH HAZARDS; LEAD; ZINC;

BIOCHEMICAL PARAMETERS; BLOOD CONCENTRATIONS; CORRELATION ANALYSIS; ENVIRONMENTAL POLLUTIONS; HEMATOLOGICAL PARAMETERS; HEMATOLOGY; HORSE; POSITIVE CORRELATIONS;

BLOOD;

CADMIUM; COPPER; LEAD; ZINC;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BIOCHEMICAL COMPOSITION; BLOOD CLOT; BLOOD COMPONENT; BLOOD SAMPLING; COPPER BLOOD LEVEL; EQUIDAE; HEMATOLOGICAL PARAMETERS; JUGULAR VEIN; LEAD BLOOD LEVEL; NONHUMAN; TRACE METAL BLOOD LEVEL; ZINC BLOOD LEVEL;

BIOCHEMISTRY; BLOOD; CADMIUM; COPPER; HEMATOLOGY; HORSE; LEAD; ZINC;

ADULT; ANIMALS; CADMIUM; COPPER; HEMATOLOGIC TESTS; HORSES; HUMANS; LEAD; MALE; ZINC;

EID: 84899508609     PISSN: 10934529     EISSN: 15324117     Source Type: Journal    
DOI: 10.1080/10934529.2014.894322     Document Type: Article

References (63)

1. Lesnik, F.; Danko, J. Determination of xenobiotics. In Xenobiotics in Relation to Health; University of Veterinary Medicine in Kosice and Faculty of Medicine in Kosice: Kosice, Slovak Republic, 2005, 7-12.
2. Soylak, M.; Colak, H.; Turkoglu, O.; Dogan, M. Trace metal content of snacks and appetizers consumed in Turkey. Bull. Environ. Contam. Toxicol. 2006, 76, 436-441.
3. Demirel, S.; Tuzen, M.; Saracoglu, S.; Soylak, M. Evaluation of various digestion procedures for trace element contents of some food materials. J. Hazard. Mater. 2008, 152, 1020-1026.
4. Massanyi, P.; Bardos, L.; Roychoudhury, S.; Stawarz, R. Foreword. J Environ. Sci. Health Pt. A 2012, 47, 1201.
5. Tvrda, E.; Knazicka, Z.; Bardos, L.; Massanyi, P.; Lukac, N. Impact of oxidative stress on male fertility-a review. Acta Vet. Hung. 2011, 59, 465-484.
6. Kolesarova, A.; Slamecka, J.; Jurcik, R.; Tataruch, F.; Lukac, N.; Kovacik, J.; Capcarova, M.; Valent, M., Massanyi, P. Environmental levels of cadmium, lead and mercury in brown hares and their relation to blood metabolic parameters. J. Environ. Sci. Health Pt. A 2008, 43, 646-650.
7. Massanyi, P.; Tataruch, F.; Slamecka, J.; Toman, R.; Jurcík, R. Accumulation of lead, cadmium, and mercury in liver and kidney of the brown hare (Lepus europaeus) in relation to the season, age, and sex in the West Slovakian Lowland. J. Environ. Sci. Health Pt. A 2003, 38, 1299-1309.
8. Holovska, K.; Cigankova, V.; Almasiova, V.; Sobekova, A.; Nad, P.; Skalicka, M. Ultrastructural and biochemical changes in the turkeys liver after the chronic cadmium exposure. Acta Vet. Beograd 2009, 59, 167-175.
9. Cigankova, V.; Almasiova, V.; Holovska, K. Morphological changes in duodenal epithelium of Japanese quail after chronic cadmium exposure. Polish J. Environ. Stud. 2010, 19, 275-282.
10. Stawarz, R.; Formicki, G.; Zakrzewski, M.; Rys, J.; Rozmus, M. Distribution of heavy metals and trace elements in human breast cancer tissue and in adjacent normal tissue of woman in Poland. Fresenium Environ. Bull. 2009, 18, 182-188.
11. Formicki, G.; Stawarz, R.; Lukac, N.; Putala, A.; Kuczkowska, A. Combined effects of cadmium and ultraviolet radiation on mortality and mineral content in common frog (Rana temporaria) larvae. J. Environ. Sci. Health Pt. A 2008, 43, 1174-1183.
12. Pasanen K.; Pukkala, E.; Turunen, A.W.; Patama, T.; Jussila, I.; Makkonen, S.; Salonen, R.O.; Verkasalo, P.K. Mortality among population with exposure to industrial air pollution containing nickel and other toxic metals. J. Occup. Environ. Med. 2012, 54, 583-591.
13. Knazicka, Z.; Lukac, N., Forgacs, Z., Tvrda, E.; Lukacova, J.; Slivkova, J.; Binkowski, L.; Massanyi, P. Effects of mercury on the steroidogenesis of human adrenocarcinoma (NCI-H295R) cell line. J. Environ. Sci. Health Pt. A 2013, 48, 348-353.
14. Toman, R.; Massanyi, P.; Adamkovicova, M.; Lukac, N.; Cabaj, M.; Martiniakova M. Quantitative histological analysis of the mouse testis after the long-term administration of nickel in feed. J. Environ. Sci. Health Pt. A 2012, 47, 1272-1279.
15. Massanyi, P.; Lukac, N.; Uhrin, V.; Toman, R.; Pivko, J.; Rafay, J.; Forgacs, Z.; Somosy, Z. Female reproductive toxicology of cadmium. Acta Biol. Hung. 2007, 58, 287-299.
16. Toman, R.; Massanyi, P.; Lukac, N.; Ducsay, L.; Golian, J. Fertility and content of cadmium in pheasant (Phasianus colchicus) following cadmium intake in drinking water. Ecotoxicol. Environ. Saf. 2005, 62, 112-117.
17. Hijova, E.; Nistiar, F. Plasma antioxidant changes after acute cadmium intoxication in rats. Acta Vet. Brno 2005, 74, 565-569.
18. Lukacinova, A.; Racz, O.; Lovasova, E.; Nistiar, F. Effect of lifetime low dose exposure to heavy metals on selected serum proteins of Wistar rats during three subsequent generations. Ecotoxicol. Environ. Saf. 2011, 74, 1747-1755.
19. Roychoudhury, S.; Massanyi, P.; Bulla, J.; Choudhury, M.D.; Straka, L.; Lukac, N.; Formicki, G.; Dankova, M.; Bardos, L. In vitro copper toxicity on rabbit spermatozoa motility, morphology and cell membrane integrity. J. Environ. Sci. Health Pt. A 2010, 45, 1482-1491.
20. Roychoudhury, S.; Massanyi, P. In vitro copper inhibition of rabbit spermatozoa motility. J. Environ. Sci. Health Pt. A 2008, 43, 658-663.
21. Dobrzanski, Z.; Koacz, R.; Bodak, E. Heavy metals in animal environment. Medycyna Wet. 1996, 52, 570-574.
22. Massanyi, P.; Trandzik, J.; Nad, P.; Korenekova, B.; Skalicka, M.; Toman, R.; Lukac, N.; Strapak, P.; Halo, M.; Turcan, J. Concentration of copper, iron, zinc, cadmium, lead and nickel in boar semen and relation to the spermatozoa quality. J. Environ. Sci. Health Pt. A 2003, 38, 2643-2651.
23. Agarwal, K.; Sharma, A.; Talukder, G. Clastogenic effects of copper sulphate on the bone marrow chromosomes of mice in vivo. Mutat. Res. 1990, 243, 1-6.
24. Dzugan, M.; Lis, M.; Droba, M.; Niedzioka, J.W. Effect of cadmium injected in ovo on hatching and the activity of plasma hydrolytic enzymes in newly hatched chicks. Acta Vet Hung. 2011, 59, 337-347.
25. Roychoudhury, S.; Massanyi, P.; Bulla, J.; Choudhury, M.D.; Lukac, N.; Filipejova, T.; Trandzik, J.; Toman, R.; Almasiova, V. Cadmium toxicity at low concentration on rabbit spermatozoa motility, morphology and membrane integrity in vitro. J. Environ. Sci. Health Pt. A 2010, 45, 1374-1383.
26. Nad, P.; Massanyi, P.; Skalicka, M.; Korenekova, B.; Cigankova, V.; Almasiova, V. The effect of cadmium in combination with zinc and selenium on ovarian structure in Japanese quails. J. Environ. Sci. Health Pt. A 2007, 42, 2017-2022.
27. Oishi, S.; Nakagawa, J.; Ando, M. Effect of cadmium administration on the endogenous metal balance in rats. Biol. Trace Elem. Res. 2000, 31, 257-278.
28. Plum, L.M.; Rink, L.; Haase, H. The essential toxin: Impact of zinc on human health. Int. J. Environ. Res. Public. Health 2010, 7, 1342-1365.
29. De Francisco, N.; Ruiz Troya, J.D.; Agüera, E.I. Lead and lead toxicity in domestic and free living birds. Avian Pathol. 2003, 32, 3-13.
30. Ferreyra, H., Romano, M.; Uhart, M. Recent and chronic exposure of wild ducks to lead in human-modified Wetlands in Santa Fe province, Argentina. J. Wildl. Dis. 2009, 45, 823-827.
31. Skalicka, M.; Korenekova, B.; Nad, P. Lead in livestock from polluted areas. Trace Elem. Electrolytes 2002, 19, 94-96.
32. Mojzis, J.; Nistiar F. Lead-induced changes of cation-osmotic hemolysis in rats. Gen. Physiol. Biophys. 2001, 20, 315-319.
33. Caciari, T.; Casale, T.; Pimpinella, B.; Montuori, L.; Trove, L.; Tomei, G.; Capozzella, A.; Schifano, M.P.; Fiaschetti, M.; Scala, B.; Tomei, F.; Rosati, M.V. Exposure to solvents in health care workers: assessment of the hepatic effects. Ann Ig. 2013, 25, 125-136.
34. Gren, A.; Barbasz, A.; Kreczmer, B.; Sieprawska, A.; Rudolphi- Skorska, E.; Filek, M. Protective effect of ascorbic acid after single and repetitive administration of cadmium in Swiss mice. Toxicol. Mech. Meth. 2012, 22, 597-604.
35. Onuegbu, A.J.; Olisekodiaka, M.J.; Nwaba, E.I.; Adeyeye, A.D.; Akinola, F.F. Assessment of some renal indices in people occupationally exposed to lead. Toxicol. Ind. Health 2011, 27, 475-479.
36. Galik, B.; Biro, D.; Halo, M.; Juracek, M.; Simko, M.; Massanyi, P.; Rolinec, M. The effect of different macrominerals intake on mineral metabolism of sport horses. Acta Vet. Brno 2012, 81, 113-117.
37. Mojzisova, J.; Massanyi, P.; Danko, J.; Trbolova, A.; Petrovova, E.; Mazensky, D.; Vdoviakova, K.; Luptakova, L.; Torma, N. Changes of the immunological and haematological parameters in rabbits after bendiocarbamate application. J. Environ. Sci. Health Pt. A 2012, 47, 1244-1248.
38. Massanyi, P.; Slamecka, J.; Lukac, N.; Capcarova, M.; Mertin, D., Jurcik, R.: Seasonal variations in the blood biochemistry in brown hare. Medycyna Wet. 2009, 65, 389-393.
39. Kolesarova, A.; Capcarova, M.; Arpasova, H.; Kalafova, A.; Massanyi, P.; Lukac, N.; Kovacik, J.; Schneidgenova, M. Nickel induced blood biochemistry alterations in hens after an experimental peroral administration. J. Environ. Sci. Health Pt. B 2008, 43, 625-632.
40. Danko, J.; Simon, F.; Artimova, J. Nomina anatomica veterinaria. University of Veterinary Medicine and Pharmacy: Kosice, Slovak Republic, 2011.
41. Massanyi, P.; Toman, R.; Valent, M.; Cupka, P. Evaluation of selected parameters of a metabolic profile and levels of cadmium in reproductive organs of rabbits after an experimental administration. Acta Physiol. Hung. 1995, 83, 267-273.
42. Capcarova, M.; Slamecka, J.; Abbas, K.; Kolesarova, A.; Kalafova, A.; Valent, M.; Filipejova, T.; Chrastinova, L.; Ondruska, L.; Massanyi, P. Effects of dietary inclusion of Rhus coriaria on internal milieu of rabbits. J. Anim. Physiol. Anim. Nutr. 2012, 96, 459-465.
43. Kramarova, M.; Massanyi, P.; Slamecka, J.; Tataruch, F.; Jancova, A.; Gasparik, J.; Fabis, M.; Kovacik, J.; Toman, R.; Galova, J.; Jurcik, R. Distribution of cadmium and lead in liver and kidney of some wild animals in Slovakia. J. Environ. Sci. Health Pt. A 2005, 40, 593-600.
44. Gasparik, J.; Massanyi, P.; Slamecka, J.; Fabis, M.; Jurcik, R. Concentration of selected metals in liver and kidney, and muscle of the red deer (Cervus elaphus). J. Environ. Sci. Health Pt. A 2004, 39, 2105-2111.
45. Gomez, G.; Baos, R.; Gomara, B.; Jimenez, B.; Benito, V.; Montoro, R.; Hiraldo, F.; González, M.J. Influence of a mine tailing accident near Doñana National Park (Spain) on heavy metals and arsenic accumulation in 14 species of waterfowl (1998 to 2000). Arch. Environ. Contam. Toxicol. 2004, 47, 521-529.
46. Nad, P.; Skalicka, M.; Korenekova, B. The effects of long-term cadmium exposure in turkeys: Accumulation and zinc prevention. J. Environ. Sci. Health Pt. A 2012, 47, 1239-1243.
47. Andreji, J.; Stranai, I.; Massanyi, P.; Valent, M. Accumulation of some metals in muscles of five fish species from lower Nitra river. J. Environ. Sci. Health Pt. A 2006, 41, 2607-2622.
48. Nagajyothi, P.C.; Dinakar, N.; Prasad, T.N.V.K.V.; Suresh, C.; Damodharam, T. Heavy metal toxicity: Industrial effluent on groundnut (Arachis hypogaea L.) seedlings. J. Appl. Sci. Res. 2008, 4, 110-121.
49. Skalicka, M.; Korenekova, B.; Nad, P. Copper in livestock from polluted area. Bull. Environ. Contam. Toxicol. 2005, 74, 740-744.
50. Yoruk, I.; Deger, Y.; Mert, H.; Mert, N. Serum concentration of copper, zinc, iron, and cobalt and the copper/zinc ratio in horses with equine herpesvirus-1. Biol. Trace Elem. Res. 2007, 118, 38-42.
51. Nussey, G.; Van Vuren, J.H.J.; Du Preez, H.H. Effect of copper on blood coagulation of Oreochromis mossambicus (Cichlidae). Comp. Biochem. Physiol. Pt. C 1995, 111, 359-367.
52. Cybulski, W; Jarosz, L; Chalabis-Mazurek, A; Jakubczak, A; Kostro, K; Kursa, K. Contents of zinc, copper, chromium and manganese in silver foxes according to their age and mineral supplementation. Pol. J. Vet. Sci. 2009, 12, 339-345.
53. Naccari, C.; Giangrosso, G.; Macaluso, A.; Billone, E.; Cicero, A.; D'Ascenzi, C.; Ferrantelli, V. Red foxes (Vulpes vulpes) bioindicator of lead and copper pollution in Sicily (Italy). Ecotoxicol. Environ. Saf. 2013, 90, 41-45.
54. Khan, S.; Khan, M.A.; Bhatnagar, D.; Yadav, P.; Sarkar, S. Zinc protection against lipid peroxidation from cadmium. Indian J. Exp. Biol. 1991, 29, 823-825.
55. [54a] Soch, M.; Broucek, J.; Srejberova, P. Hematology and blood microelements of sheep in south Bohemia. Biologia 2011, 66, 181-186.
56. Soch, M.; Broucek, J.; Srejberova, P. Effect of selected factors on mineral parameters in plasma of cows. Arch. Tierzucht 2010, 53, 510-519.
57. Bires, J.; Bartko, P.; Huska, M.; Biresova, M. Distribution of risk elements in the organism of sheep after industrial intoxication with zinc. Spectrosc. Lett. 1997, 30, 1263-1277.
58. Rovira, J.; Mari, M.; Nadal, M.; Schuhmacher, M.; Domingo, J.L. Levels of metals and PCDD/Fs in the vicinity of a cement plant: Assessment of human health risks. J. Environ. Sci. Health Pt. A 2011, 46, 1075-1084.
59. Liu, Z.P. Lead poisoning combined with cadmium in sheep and horses in the vicinity of non-ferrous metal smelters. Sci. Total Environ. 2003, 309, 117-126.
60. Massanyi, P.; Toman, R.; Valent, M.; Jones, Q. Serum mineral profile of rabbits after an experimental administration of cadmium. J. Environ. Sci. Health Pt. A 1995, 30, 2221-2227.
61. Maret, W.; Sandstead, H.H. Zinc requirements and the risks and benefits of zinc supplementation. J. Trace Elem. Med. Biol. 2006, 20, 3-18.
62. Korenekova, B.; Skalicka, M.; Nad, P. Zinc in cattle from area polluted by long-term emissions. Bull. Environ. Contam. Toxicol. 2006, 76, 684-688.
63. Pain, D.J. Lead in Waterfowl; Beyer, W.N.; Heinz, G.H.; Redmon-Norwood, A.W., Eds.; Lewis: Boca Raton, FL, 1996.