Preparation and evaluation of colon adhesive pellets of 5-aminosalicylic acid

International Journal of Pharmaceutics

Volumn 468, Issue 1-2, 2014, Pages 165-171

  Xu, Meixia ^a   Sun, Minjie ^a   Qiao, Hongzhi ^a   Ping, Qineng ^a   Elamin, Eltayeb Suliman ^a,b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Department of Pharmaceutics Omudrman Islamic University   (Sudan)

Author keywords

5 Aminosalicylic acid; Bioadhesion; Colon specific delivery; Extrusion spheronization; Pharmacodynamics

Indexed keywords

2,4,6 TRINITROBENZENE SULFONIC ACID; CORPORATION JAPAN CARBOMER 940; ETHYL CELLULOSE; ETIASA; EUDRAGIT; MALONALDEHYDE; MESALAZINE; MICROCRYSTALLINE CELLULOSE 101; MYELOPEROXIDASE; SUPEROXIDE DISMUTASE; TRINITROBENZENESULFONIC ACID; UNCLASSIFIED DRUG; ACRYLIC ACID RESIN; BIOLOGICAL MARKER; CARBOPOL 940; CELLULOSE; DRUG CARRIER; ENTERIC COATED TABLET; EXCIPIENT; HYDROXYPROPYLCELLULOSE; METHYLMETHACRYLATE-METHACRYLIC ACID COPOLYMER; MICROCRYSTALLINE CELLULOSE; NONSTEROID ANTIINFLAMMATORY AGENT; POLYMETHACRYLIC ACID DERIVATIVE;

ANGLE OF REPOSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG MEGADOSE; DRUG PELLET; DRUG RELEASE; DRUG SCREENING; DRUG SOLUBILITY; ENTERIC COATED TABLET; LOW DRUG DOSE; MALE; MUCOADHESION; NONHUMAN; PELLET EXTRUSION; PRIORITY JOURNAL; RAT; SPHERONIZATION; THERAPY EFFECT; ULCERATIVE COLITIS; ADHESION; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICALLY INDUCED; CHEMISTRY; COLITIS, ULCERATIVE; COLON; DISEASE MODEL; DRUG EFFECTS; EVALUATION STUDY; KINETICS; MEDICINAL CHEMISTRY; METABOLISM; ORAL DRUG ADMINISTRATION; PATHOLOGY; PHARMACEUTICS; PROCEDURES; SOLUBILITY; SPRAGUE DAWLEY RAT;

ACRYLIC RESINS; ADHESIVENESS; ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOLOGICAL MARKERS; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; COLITIS, ULCERATIVE; COLON; DISEASE MODELS, ANIMAL; DRUG CARRIERS; EXCIPIENTS; KINETICS; MALE; MESALAMINE; POLYMETHACRYLIC ACIDS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; TABLETS, ENTERIC-COATED; TECHNOLOGY, PHARMACEUTICAL; TRINITROBENZENESULFONIC ACID;

EID: 84899497920     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.04.040     Document Type: Article

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