메뉴 건너뛰기




Volumn 51, Issue 4, 2006, Pages 698-705

Antioxidant therapy with N-acetylcysteine plus mesalamine accelerates mucosal healing in a rodent model of colitis

Author keywords

Colitis; N acetylcysteine plus mesalamine

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CYTOKINE; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; MESALAZINE; MYELOPEROXIDASE; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA;

EID: 33645883230     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-006-3194-z     Document Type: Article
Times cited : (34)

References (28)
  • 2
    • 0032981042 scopus 로고    scopus 로고
    • Novel therapies for inflammatory bowel disease
    • Sands BE: Novel therapies for inflammatory bowel disease. Gastroenterol Clin North Am 18:323-351, 1999
    • (1999) Gastroenterol Clin North Am , vol.18 , pp. 323-351
    • Sands, B.E.1
  • 3
    • 0002218823 scopus 로고    scopus 로고
    • Crohn's disease
    • M Feldman, LS Friedman, MH Sleisenger (eds). New York, Saunders
    • Sands BE: Crohn's disease. In Gastrointestinal and Liver Disease. M Feldman, LS Friedman, MH Sleisenger (eds). New York, Saunders, 2002, pp 2005-2038
    • (2002) Gastrointestinal and Liver Disease , pp. 2005-2038
    • Sands, B.E.1
  • 4
    • 0027959253 scopus 로고
    • Oxidants and free radicals in inflammatory bowel disease
    • Grisham MB: Oxidants and free radicals in inflammatory bowel disease. Lancet B44:859-861, 1994
    • (1994) Lancet , vol.B44 , pp. 859-861
    • Grisham, M.B.1
  • 6
    • 0029115715 scopus 로고
    • Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity
    • Rachmilewitz D, Karmeli F, Okon E, Bursztyn M: Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity. Gut 37:247-255, 1995
    • (1995) Gut , vol.37 , pp. 247-255
    • Rachmilewitz, D.1    Karmeli, F.2    Okon, E.3    Bursztyn, M.4
  • 8
    • 0032712861 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in Trinitrobenzene sulphonic acid induced colitis in mice
    • McCafferty DM, Miampamba M, Shiota E: Role of inducible nitric oxide synthase in Trinitrobenzene sulphonic acid induced colitis in mice. Gut 45:199-209, 1999
    • (1999) Gut , vol.45 , pp. 199-209
    • McCafferty, D.M.1    Miampamba, M.2    Shiota, E.3
  • 9
    • 0034074793 scopus 로고    scopus 로고
    • Replenishment of glutathione levels improves mucosal function in experimental acute colitis
    • Ardite E, Sans M, Panés J, Romero FJ, Pique JM, Fernandez-Checa JC: Replenishment of glutathione levels improves mucosal function in experimental acute colitis. Lab Invest 80:735-744, 2000
    • (2000) Lab Invest , vol.80 , pp. 735-744
    • Ardite, E.1    Sans, M.2    Panés, J.3    Romero, F.J.4    Pique, J.M.5    Fernandez-Checa, J.C.6
  • 12
    • 0023934636 scopus 로고
    • Release of platelet-activating factor (PAF) and accelerated healing induced by a PAF antagonist in an animal model of chronic colitis
    • Wallace JI: Release of platelet-activating factor (PAF) and accelerated healing induced by a PAF antagonist in an animal model of chronic colitis. Can J Physiol Pharmacol 66:422-425, 1988
    • (1988) Can J Physiol Pharmacol , vol.66 , pp. 422-425
    • Wallace, J.I.1
  • 13
    • 0344466539 scopus 로고    scopus 로고
    • The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through down regulation of cytokine production
    • Galvez J, Garrido M, Rodriguez-Cabezas ME, Ramis I, de Medina FS, Merlos M, Zarzuelo A: The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through down regulation of cytokine production. Inflamm Bowel Dis 9:363-371, 2003
    • (2003) Inflamm Bowel Dis , vol.9 , pp. 363-371
    • Galvez, J.1    Garrido, M.2    Rodriguez-Cabezas, M.E.3    Ramis, I.4    De Medina, F.S.5    Merlos, M.6    Zarzuelo, A.7
  • 15
    • 0034177606 scopus 로고    scopus 로고
    • A radical approach to treating inflammation
    • Grisham MB: A radical approach to treating inflammation. Trends Pharmacol Sci 21:119-120, 2000
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 119-120
    • Grisham, M.B.1
  • 16
    • 0033637218 scopus 로고    scopus 로고
    • Mesalamine inhibits activation of transcription factor NF-kB in inflamed mucosa of patients with ulcerative colitis
    • Bantel H, Berg C, Vieth M, Stolte M, Kruis W, Schulze-Osthoff K: Mesalamine inhibits activation of transcription factor NF-kB in inflamed mucosa of patients with ulcerative colitis. Am J Gastroenterol 95:3452-3457, 2000
    • (2000) Am J Gastroenterol , vol.95 , pp. 3452-3457
    • Bantel, H.1    Berg, C.2    Vieth, M.3    Stolte, M.4    Kruis, W.5    Schulze-Osthoff, K.6
  • 17
    • 0033636562 scopus 로고    scopus 로고
    • Progress in understanding the mechanism of action of 5-aminosalicylic acid
    • MacDermott RP: Progress in understanding the mechanism of action of 5-aminosalicylic acid. Am J Gastroenterol 95:3343-3345, 2000
    • (2000) Am J Gastroenterol , vol.95 , pp. 3343-3345
    • MacDermott, R.P.1
  • 20
    • 0027414728 scopus 로고
    • Inhibition of leukocyte adhesion molecule upregulation by tumor necrosis factor α: A novel mechanism of action of sulfasalazine
    • Green field SM, Hambhin AS, Shakoor ZS, Teare JP, Punchard NA, Thompson RP: Inhibition of leukocyte adhesion molecule upregulation by tumor necrosis factor α: a novel mechanism of action of sulfasalazine. Gut 34:252-256, 1993
    • (1993) Gut , vol.34 , pp. 252-256
    • Greenfield, S.M.1    Hambhin, A.S.2    Shakoor, Z.S.3    Teare, J.P.4    Punchard, N.A.5    Thompson, R.P.6
  • 21
    • 0025321145 scopus 로고
    • Role of reactive oxygen metabolites in experimental colitis
    • Keshavarzian, A, Morgan G, Sedghi S, Gordon JH, Doria M: Role of reactive oxygen metabolites in experimental colitis. Gut 31:786-790, 1990
    • (1990) Gut , vol.31 , pp. 786-790
    • Keshavarzian, A.1    Morgan, G.2    Sedghi, S.3    Gordon, J.H.4    Doria, M.5
  • 22
    • 0024212465 scopus 로고
    • SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis
    • Miller MJ, McNeill H, Mullane KM, Caravella SJ, Clark DA: SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis. Am J Physiol 255:G556-G565, 1988
    • (1988) Am J Physiol , vol.255
    • Miller, M.J.1    McNeill, H.2    Mullane, K.M.3    Caravella, S.J.4    Clark, D.A.5
  • 24
    • 0029115715 scopus 로고
    • Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity
    • Rachmilewitz D, Karmeli F, Okon E, Bursztyn M: Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity. Gut 37:247-255, 1995
    • (1995) Gut , vol.37 , pp. 247-255
    • Rachmilewitz, D.1    Karmeli, F.2    Okon, E.3    Bursztyn, M.4
  • 26
    • 0032712861 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in trinitrobenzene sulphonic acid induced colitis in mice
    • McCafferty DM, Miampamba M, Shiota E, Sharkey KA, Kubes P: Role of inducible nitric oxide synthase in trinitrobenzene sulphonic acid induced colitis in mice. Gut 45:864-873, 1999
    • (1999) Gut , vol.45 , pp. 864-873
    • McCafferty, D.M.1    Miampamba, M.2    Shiota, E.3    Sharkey, K.A.4    Kubes, P.5
  • 27
    • 0032855666 scopus 로고    scopus 로고
    • Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase
    • Zingarelli B, Szabo C, Salzman AL: Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase. Gut 45:199-209, 1999
    • (1999) Gut , vol.45 , pp. 199-209
    • Zingarelli, B.1    Szabo, C.2    Salzman, A.L.3
  • 28
    • 0034253943 scopus 로고    scopus 로고
    • Nitric oxide and intestinal inflammation
    • Kubes P, McCafferty DM: Nitric oxide and intestinal inflammation. Am J Med 109:150-158, 2000
    • (2000) Am J Med , vol.109 , pp. 150-158
    • Kubes, P.1    McCafferty, D.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.