Neutrophil cathepsin G, but not elastase, induces aggregation of MCF-7 mammary carcinoma cells by a protease activity-dependent cell-oriented mechanism

Mediators of Inflammation

Volumn 2014, Issue , 2014, Pages

  Yui, Satoru ^a   Osawa, Yuuki ^a   Ichisugi, Takeo ^a   Morimoto Kamata, Riyo ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLSULFONYL FLUORIDE; CATHEPSIN G; CELL ADHESION MOLECULE; ELASTASE; FIBRONECTIN; LEUKOCYTE ELASTASE; POLYLYSINE; VITRONECTIN; PANCREATIC ELASTASE;

ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CARCINOMA CELL; CELL ADHESION; CELL AGGREGATION; CELL MOTILITY; CELL MOTION; CELL STRAIN MCF 7; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; HUMAN; HUMAN CELL; NEUTROPHIL; PROTEIN DEGRADATION; DRUG EFFECTS; MCF 7 CELL LINE;

CATHEPSIN G; CELL AGGREGATION; CELL MOVEMENT; HUMANS; MCF-7 CELLS; PANCREATIC ELASTASE; PHENYLMETHYLSULFONYL FLUORIDE;

EID: 84899477800     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2014/971409     Document Type: Article

References (38)

1. Canel M., Serrels A., Frame M. C., Brunton V. G., E-cadherin-integrin crosstalk in cancer invasion and metastasis. Journal of Cell Science 2013 126 2 393 401
2. Woodhouse E. C., Chuaqui R. F., Liotta L. A., General mechanisms of metastasis. Cancer 1997 80 8 1529 1537 2-s2.0-0030769477 (Pubitemid 27444024)
3. Gui G. P. H., Puddefoot J. R., Vinson G. P., Wells C. A., Carpenter R., Altered cell-matrix contact: a prerequisite for breast cancer metastasis? British Journal of Cancer 1997 75 5 623 633 2-s2.0-0031054202 (Pubitemid 27091073)
4. Nicolson G. L., Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites. Biochimica et Biophysica Acta 1988 948 2 175 224 2-s2.0-0023770128 (Pubitemid 18263874)
5. Cavallaro U., Christofori G., Cell adhesion in tumor invasion and metastasis: loss of the glue is not enough. Biochimica et Biophysica Acta 2001 1552 1 39 45 2-s2.0-0035977205 10.1016/S0304-419X(01)00038-5 (Pubitemid 34066627)
6. Fidler I. J., The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis. European Journal of Cancer 1973 9 3 223 227 2-s2.0-0015603212
7. Liotta L. A., Kleinerman J., Saidel G. M., The significance of hematogenous tumor cell clumps in the metastatic process. Cancer Research 1976 36 3 889 894 2-s2.0-0017234894
8. Tomlinson J. S., Alpaugh M. L., Barsky S. H., An intact overexpressed E-cadherin/ α β -catenin axis characterizes the lymphovascular emboli of inflammatory breast carcinoma. Cancer Research 2001 61 13 5231 5241 2-s2.0-0035392961 (Pubitemid 32681558)
9. Russell S. W., Gillespie G. Y., Hansen C. B., Cochrane C. G., Inflammatory cells in solid murine neoplasms. II. Cell types found throughout the course of Moloney sarcoma regression or progression. International Journal of Cancer 1976 18 3 331 338 2-s2.0-0017097550
10. Balkwill F., Mantovani A., Inflammation and cancer: back to Virchow? The Lancet 2001 357 9255 539 545 2-s2.0-0035901090 10.1016/S0140-6736(00)04046-0 (Pubitemid 32173595)
11. Brigati C., Noonan D. M., Albini A., Benelli R., Tumors and inflammatory infiltrates: friends or foes? Clinical and Experimental Metastasis 2002 19 3 247 258 2-s2.0-0036105771 10.1023/A:1015587423262 (Pubitemid 34553525)
12. Di Carlo E., Forni G., Lollini P., Colombo M. P., Modesti A., Musiani P., The intriguing role of polymorphonuclear neutrophils in antitumor reactions. Blood 2001 97 2 339 345 2-s2.0-0035863830 10.1182/blood.V97.2.339 (Pubitemid 32060315)
13. Piccard H., Muschel R. J., Opdenakker G., On the dual roles and polarized phenotypes of neutrophils in tumor development and progression. Critical Reviews in Oncology/Hematology 2012 82 3 296 309 2-s2.0-79960567818 10.1016/j.critrevonc.2011.06.004
14. Yui S., Tomita K., Kudo T., Ando S., Yamazaki M., Induction of multicellular 3-D spheroids of MCF-7 breast carcinoma cells by neutrophil-derived cathepsin G and elastase. Cancer Science 2005 96 9 560 570 2-s2.0-27144503317 10.1111/j.1349-7006.2005.00097.x (Pubitemid 41488419)
15. Kudo T., Kigoshi H., Hagiwara T., Takino T., Yamazaki M., Yui S., Cathepsin G, a neutrophil protease, induces compact cell-cell adhesion in MCF-7 human breast cancer cells. Mediators of Inflammation 2009 2009 11 2-s2.0-71449125546 10.1155/2009/850940 850940
16. Owen C. A., Campbell E. J., The cell biology of leukocyte-mediated proteolysis. Journal of Leukocyte Biology 1999 65 2 137 150 2-s2.0-0033056463 (Pubitemid 29077006)
17. Pham C. T. N., Neutrophil serine proteases: specific regulators of inflammation. Nature Reviews Immunology 2006 6 7 541 550 2-s2.0-33745559712 10.1038/nri1841 (Pubitemid 43980526)
18. Newman S. L., Gootee L., Gabay J. E., Selsted M. E., Identification of constituents of human neutrophil azurophil granules that mediate fungistasis against Histoplasma capsulatum. Infection and Immunity 2000 68 10 5668 5672 2-s2.0-0033802422 10.1128/IAI.68.10.5668-5672.2000
19. Shafer W. M., Hubalek F., Huang M., Pohl J., Bactericidal activity of a synthetic peptide (CG 117-136) of human lysosomal cathepsin G is dependent on arginine content. Infection and Immunity 1996 64 11 4842 4845 2-s2.0-0029966173 (Pubitemid 26357101)
20. Hahn I., Klaus A., Janze A.-K., Steinwede K., Ding N., Bohling J., Brumshagen C., Serrano H., Gauthier F., Paton J. C., Welte T., Maus U. A., Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice. Infection and Immunity 2011 79 12 4893 4901 2-s2.0-84855720149 10.1128/IAI.05593-11
21. Selak M. A., Smith J. B., Cathepsin G binding to human platelets. Evidence for a specific receptor. Biochemical Journal 1990 266 1 55 62 2-s2.0-0025020105 (Pubitemid 20069020)
22. Sambrano G. R., Huang W., Faruqi T., Mahrus S., Craik C., Coughlin S. R., Cathepsin G activates protease-activated receptor-4 in human platelets. The Journal of Biological Chemistry 2000 275 10 6819 6823 2-s2.0-0034629468 10.1074/jbc.275.10.6819 (Pubitemid 30146221)
23. Sun R., Iribarren P., Zhang N., Zhou Y., Gong W., Cho E. H., Lockett S., Chertov O., Bednar F., Rogers T. J., Oppenheim J. J., Wang J. M., Identification of neutrophil granule protein cathepsin G as a novel chemotactic agonist for the G protein-coupled formyl peptide receptor. The Journal of Immunology 2004 173 1 428 436 2-s2.0-2942750278 (Pubitemid 38797369)
24. Uehara A., Muramoto K., Takada H., Sugawara S., Neutrophil serine proteinases activate human nonepithelial cells to produce inflammatory cytokines through protease-activated receptor 2. The Journal of Immunology 2003 170 11 5690 5696 2-s2.0-0037797300 (Pubitemid 36621425)
25. Glusa E., Adam C., Endothelium-dependent relaxation induced by cathepsin G in porcine pulmonary arteries. British Journal of Pharmacology 2001 133 3 422 428 2-s2.0-0034761323 (Pubitemid 33027779)
26. Sabri A., Alcott S. G., Elouardighi H., Pak E., Derian C., Andrade-Gordon P., Kinnally K., Steinberg S. F., Neutrophil cathepsin G promotes detachment-induced cardiomyocyte apoptosis via a protease-activated receptor-independent mechanism. The Journal of Biological Chemistry 2003 278 26 23944 23954 2-s2.0-0037592155 10.1074/jbc.M302718200 (Pubitemid 36830223)
27. Iacoviello L., Kolpakov V., Salvatore L., Amore C., Pintucci G., de Gaetano G., Donati M. B., Human endothelial cell damage by neutrophil-derived cathepsin G role of cytoskeleton rearrangement and matrix-bound plasminogen activator inhibitor-1. Arteriosclerosis, Thrombosis, and Vascular Biology 1995 15 11 2037 2046 10.1161/01.ATV.15.11.2037
28. Morimoto-Kamata R., Mizoguchi S., Ichisugi T., Yui S., Cathepsin G induces cell aggregation of human breast cancer MCF-7 via a 2-step mechanism: enzymatic activity-independent binding to the cell surface and enzymatic activity-dependent induction of the cell aggregation. Mediators of Inflammation 2012 2012 13 10.1155/2012/456462 456462
29. Wiedow O., Meyer-Hoffert U., Neutrophil serine proteases: potential key regulators of cell signalling during inflammation. Journal of Internal Medicine 2005 257 4 319 328 2-s2.0-16244397365 (Pubitemid 40461184)
30. McDonald J. A., Kelley D. G., Degradation of fibronectin by human leukocyte elastase. Release of biologically active fragments. The Journal of Biological Chemistry 1980 255 18 8848 8858 2-s2.0-0019200629 (Pubitemid 11211537)
31. Vartio T., Seppä H., Vaheri A., Susceptibility of soluble and matrix fibronectins to degradation by tissue proteinases, mast cell chymase and cathepsin G. The Journal of Biological Chemistry 1981 256 1 471 477 2-s2.0-0019876460
32. Bonnefoy A., Legrand C., Proteolysis of subendothelial adhesive glycoproteins (fibronectin, thrombospondin, and von Willebrand factor) by plasmin, leukocyte cathepsin G, and elastase. Thrombosis Research 2000 98 4 323 332 2-s2.0-0034657657 10.1016/S0049-3848(99)00242-X (Pubitemid 30255936)
33. Underwood P. A., Bennett F. A., A comparison of the biological activities of the cell-adhesive proteins vitronectin and fibronectin. Journal of Cell Science 1989 93 4 641 649 2-s2.0-0024440425 (Pubitemid 19222382)
34. Takeichi M., The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development 1988 102 4 639 655 2-s2.0-0023926935
35. Nakajima K., Powers J. C., Ashe B. M., Zimmerman M., Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site. The Journal of Biological Chemistry 1979 254 10 4027 4032 (Pubitemid 9178816)
36. Owen C. A., Campbell E. J., Neutrophil proteinases and matrix degradation. The cellbiology of pericellular proteolysis. Seminars in Cell Biology 1995 6 6 367 376 2-s2.0-0029443042
37. Zen K., Guo Y.-L., Li L.-M., Bian Z., Zhang C.-Y., Liu Y., Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis. Blood 2011 117 18 4885 4894 2-s2.0-79955960587 10.1182/blood-2010-05-287722
38. Raptis S. Z., Shapiro S. D., Simmons P. M., Cheng A. M., Pham C. T. N., Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering. Immunity 2005 22 6 679 691 2-s2.0-20444433960 10.1016/j.immuni.2005.03.015 (Pubitemid 40814499)