Impaired Cerebral autoregulation is associated with vasospasm and delayed cerebral ischemia in subarachnoid hemorrhage

Stroke

Volumn 45, Issue 3, 2014, Pages 677-682

  Otite, Fadar ^a,d   Mink, Susanne ^a,e   Tan, Can Ozan ^b,d   Puri, Ajit ^f   Zamani, Amir A ^a,d   Mehregan, Aujan ^a,d   Chou, Sherry ^a,d   Orzell, Susannah ^a,d   Purkayastha, Sushmita ^c,d   Du, Rose ^a,d   Sorond, Farzaneh A ^a,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b and Red Sox Foundation and Massachusetts General Hospital Home Base Program   (United States)

^c Hebrew Senior Life Institute for Aging Research   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e Klinikum Worms   (Germany)

^f UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Cerebrovascular circulation; Doppler; Subarachnoid hemorrhage; Ultrasonography

Indexed keywords

ADULT; AREA UNDER THE CURVE; ARTICLE; AUTOREGULATION; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BRAIN ANGIOGRAPHY; BRAIN BLOOD FLOW; BRAIN CIRCULATION; BRAIN ISCHEMIA; BRAIN VASOSPASM; CEREBRAL AUTOREGULATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DECISION TREE; DELAYED CEREBRAL ISCHEMIA; DIGITAL SUBTRACTION ANGIOGRAPHY; DOPPLER ECHOGRAPHY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NERVOUS SYSTEM PARAMETERS; OSCILLATION; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SUBARACHNOID HEMORRHAGE; TRANSCRANIAL DOPPLER; TRANSFER FUNCTION GAIN; TRANSFER FUNCTION PHASE; AGE; AGED; DOPPLER FLOWMETRY; ECHOGRAPHY; HOMEOSTASIS; PATHOPHYSIOLOGY; PHYSIOLOGY; RISK ASSESSMENT; RISK FACTOR; SMOKING; STATISTICAL MODEL;

CEREBROVASCULAR CIRCULATION; SUBARACHNOID HEMORRHAGE; ULTRASONOGRAPHY, DOPPLER;

AGE FACTORS; AGED; AREA UNDER CURVE; BRAIN ISCHEMIA; CEREBRAL ANGIOGRAPHY; CEREBROVASCULAR CIRCULATION; FEMALE; HOMEOSTASIS; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; RISK FACTORS; ROC CURVE; SMOKING; SUBARACHNOID HEMORRHAGE; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; VASOSPASM, INTRACRANIAL;

EID: 84899475822     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.002630     Document Type: Article

References (30)

1. Connolly ES Jr, Rabinstein AA, Carhuapoma JR, Derdeyn CP, Dion J, Higashida RT, et al; American Heart Association Stroke Council; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; Council on Cardiovascular Surgery and Anesthesia; Council on Clinical Cardiology. Guidelines for the management of aneurysmal subarachnoid hemorrhage: A guideline for healthcare professionals from the American Heart Association/american Stroke Association. Stroke. 2012;43:1711-1737.
2. Friedman JA, Goerss SJ, Meyer FB, Piepgras DG, Pichelmann MA, Mclver JI, et al. Volumetric quantification of Fisher Grade 3 aneurysmal subarachnoid hemorrhage: A novel method to predict symptomatic vasospasm on admission computerized tomography scans. J Neumsurg. 2002;97:401-407.
3. Charpentier C, Audibert G, Guillemin F, Civit T, Ducrocq X, Bracard S, et al. Multivariate analysis of predictors of cerebral vasospasm occurrence after aneurysmal subarachnoid hemorrhage. Stroke. 1999;30: 1402-1408.
4. Dupont SA, Wijdicks EF, Manno EM, Lanzino G, Rabinstein AA. Prediction of angiographic vasospasm after aneurysmal subarachnoid hemorrhage: value of the Hijdra sum scoring system. Neumcrit Care. 2009;11:172-176.
5. de Rooij NK, Rinkel GJ, Dankbaar JW, Frijns CJ. Delayed cerebral ischemia after subarachnoid hemorrhage: A systematic review of clinical, laboratory, and radiological predictors. Stroke. 2013;44:43-54.
6. Kruyt ND, Biessels GJ, de Haan RJ, Vermeulen M, Rinkel GJ, Coert B, et al. Hyperglycemia and clinical outcome in aneurysmal subarachnoid hemorrhage: A meta- Analysis. Stroke. 2009;40:e424-e430.
7. Lam JM, Smielewski P, Czosnyka M, Pickard JD, Kirkpatrick PJ. Predicting delayed ischemic deficits after aneurysmal subarachnoid hemorrhage using a transient hyperemic response test of cerebral auto- regulation. Neurosurgery. 2000;47:819-825, discussions 825.
8. Jaeger M, Soehle M, Schuhmann MU, Meixensberger J. Clinical significance of impaired cerebrovascular autoregulation after severe aneurysmal subarachnoid hemorrhage. Stroke. 2012, 43:2097-2101.
9. Jaeger M, Schuhmann MU, Soehle M, Nagel C, Meixensberger J. Continuous monitoring of cerebrovascular autoregulation after subarachnoid hemorrhage by brain tissue oxygen pressure reactivity and its relation to delayed cerebral infarction. Stroke. 2007;38:981-986.
10. Budohoski KP, Czosnyka M, Smielewski P, Kasprowicz M, Helmy A, Bulters D, et al. Impairment of cerebral autoregulation predicts delayed cerebral ischemia after subarachnoid hemorrhage: A prospective observational study. Stroke. 2012;43:3230-3237.
11. Pickard JD, Matheson M, Patterson J, Wyper D. Prediction of late ischemic complications after cerebral aneurysm surgery by the intraoperative measurement of cerebral blood flow. J Neumsurg. 1980;53:305-308.
12. Lang EW, Diehl RR, Mehdorn HM. Cerebral autoregulation testing after aneurysmal subarachnoid hemorrhage: The phase relationship between arterial blood pressure and cerebral blood flow velocity. Crit Care Med. 2001;29:158-163.
13. Rätsep T, Asser T. Cerebral hemodynamic impairment after aneurysmal subarachnoid hemorrhage as evaluated using transcranial doppler ultrasonography: relationship to delayed cerebral ischemia and clinical outcome. J Neurosurg. 2001;95:393-401.
14. Budohoski KP, Czosnyka M, Kirkpatrick PJ, Smielewski P, Steiner LA, Pickard JD. Clinical relevance of cerebral autoregulation following subarachnoid haemorrhage. Nat Rev Neurol. 2013;9:152-163.
15. Bederson JB, Connolly ES Jr, Batjer HH, Dacey RG, Dion JE, Diringer MN, et al; American Heart Association. Guidelines for the management of aneurysmal subarachnoid hemorrhage: A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke. 2009;40:994-1025.
16. Etminan N, Beseoglu K, Heiroth HJ, Turowski B, Steiger HJ, Hanggi D. Early perfusion computerized tomography imaging as a radiographic surrogate for delayed cerebral ischemia and functional outcome after subarachnoid hemorrhage. Stroke. 2013;44:1260-1266.
17. Vergouwen MD, Vermeulen M, van Gijn J, Rinkel GJ, Wijdicks EF, Muizelaar JP, et al. Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: proposal of a multidisciplinary research group. Stroke. 2010;41:2391-2395.
18. Vergouwen MD; Participants in the International Multi-Disciplinary Consensus Conference on the Critical Care Management of Subarachnoid Hemorrhage. Vasospasm versus delayed cerebral ischemia as an outcome event in clinical trials and observational studies. Neumcrit Care. 2011;15:308-311.
19. Sorond FA, Khavari R, Serrador JM, Lipsitz LA. Regional cerebral autoregulation during orthostatic stress: Age-related differences. J Gerontol A Biol Sci Med Sci. 2005;60:1484-1487.
20. Onder G, Petrovic M, Tangiisuran B, Meinardi MC, Markito-Notenboom WP, Somers A, et al. Development and validation of a score to assess risk of adverse drug reactions among in-hospital patients 65 years or older: The GerontoNet ADR risk score. Arch Intern Med. 2010;170:1142-1148.
21. Ntaios G, Faouzi M, Ferrari J, Lang W, Vemmos K, Michel P. An integer-based score to predict functional outcome in acute ischemic stroke: The ASTRAL score. Neurology. 2012;78:1916-1922.
22. Smith EE, Shobha N, Dai D, Olson DM, Reeves MJ, Saver JL, et al. Risk score for in-hospital ischemic stroke mortality derived and validated within the Get with the Guidelines-Stroke Program. Circulation. 2010;122:1496-1504.
23. Harrell FE Jr, Lee KL, Mark DB. Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med. 1996;15:361-387.
24. Lysakowski C, Walder B, Costanza MC, Tramfcr MR. Transcranial Doppler versus angiography in patients with vasospasm due to a ruptured cerebral aneurysm: A systematic review. Stroke. 2001;32:2292-2298.
25. Carrera E, Schmidt JM, Oddo M, Ostapkovich N, Claassen J, Rincon F, et al. Transcranial Doppler ultrasound in the acute phase of aneurysmal subarachnoid hemorrhage. Cerebrovasc Dis. 2009;27:579-584.
26. Soehle M, Czosnyka M, Pickard JD, Kirkpatrick PJ. Continuous assessment of cerebral autoregulation in subarachnoid hemorrhage. Anesth Analg. 2004;98:1133-1139.
27. Tan CO, Taylor JA. Integrative physiological and computational approaches to understand autonomic control of cerebral autoregulation. Exp Physiol. November 1, 2013. doi: 10.1113/expphysiol.2013.072355.: http://ep.physoc.org/ content/early/2013/ll/01/expphysiol.2013.072355. Accessed November 4, 2013.
28. Tan CO, Hamner JW, Taylor JA. The role of myogenic mechanisms in human cerebrovascular regulation. J Physiol. 2013;591 (pt 20):5095-5105.
29. Torbey MT, Hauser TK, Bhardwaj A, Williams MA, Ulatowski JA, Mirski MA, et al. Effect of age on cerebral blood flow velocity and incidence of vasospasm after aneurysmal subarachnoid hemorrhage. Stroke. 2001;32:2005-2011.
30. Jabbarli R, Glasker S, Weber J, Taschner C, Olschewski M, Van Velthoven V. Predictors of severity of cerebral vasospasm caused by aneurysmal subarachnoid hemorrhage. J Stroke Cerebrovasc Dis. 2013;22:1332-1339.