Genetic susceptibility to chronic otitis media with effusion: Candidate gene single nucleotide polymorphisms

Laryngoscope

Volumn 124, Issue 5, 2014, Pages 1229-1235

  MacArthur, Carol J ^a,c   Wilmot, Beth ^a,b   Wang, Linda ^d   Schuller, Michael ^a   Lighthall, Jessyka ^a   Trune, Dennis ^a,c  

^a Department of Otolaryngology Head and Neck Surgery ^*  (United States)

^b Oregon Clinic   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

genetics; innate immune system; Otitis media; single nucleotide polymorphisms

Indexed keywords

GENOMIC DNA; MUCIN 5B; SMAD2 PROTEIN; SMAD4 PROTEIN; TOLL LIKE RECEPTOR 4;

ADOLESCENT; ADULT; ARTICLE; CASE CONTROL STUDY; CHILD; CHRONIC SECRETORY OTITIS MEDIA; CONTROLLED STUDY; DNA EXTRACTION; DNA HYBRIDIZATION; FEMALE; GENE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MUC5B GENE; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SMAD2 GENE; SMAD4 GENE; TLR4 GENE;

GENETICS; INNATE IMMUNE SYSTEM; OTITIS MEDIA; SINGLE NUCLEOTIDE POLYMORPHISMS;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INFANT; MALE; MUCIN-5B; OTITIS MEDIA WITH EFFUSION; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SMAD2 PROTEIN; SMAD4 PROTEIN; TOLL-LIKE RECEPTOR 4;

EID: 84899413509     PISSN: 0023852X     EISSN: 15314995     Source Type: Journal    
DOI: 10.1002/lary.24349     Document Type: Article

References (37)

1. Teele DQ LJ, Rosner B,. The Greater Boston Otitis Media Study Group: Epidemiology of otitis media during the first seven years of life in children in Greater Boston: a prospective cohort study. J Infect Dis 1989; 160: 83-94.
2. Godinho RN, Goncalves TM, Nunes FB, et al. Prevalence and impact of chronic otitis media in school age children in Brazil. First epidemiologic study concerning chronic otitis media in Latin America. Int J Pediatr Otorhinolaryngol 2001; 61: 223-232.
3. Pichichero ME,. Recurrent and persistent otitis media. Pediatr Infect Dis J 2000; 19: 911-916.
4. Klein JO,. The burden of otitis media. Vaccine 2000; 19 (suppl 1): S2-S8.
5. Kogan MD, Overpeck MD, Hoffman HJ, Casselbrant ML,. Factors associated with tympanostomy tube insertion among preschool-aged children in the United States. Am J Public Health 2000; 90: 245-250.
6. Leskinen K,. Complications of acute otitis media in children. Curr Allergy Asthma Rep 2005; 5: 308-312.
7. Oestreicher-Kedem Y, Raveh E, Kornreich L, Popovtzer A, Buller N, Nageris B,. Complications of mastoiditis in children at the onset of a new millennium. Ann Otol Rhinol Laryngol 2005; 114: 147-152.
8. Gates GA,. Cost-effectiveness considerations in otitis media treatment. Otolaryngol Head Neck Surg 1996; 114: 525-530.
9. Casselbrant ML, Mandel EM, Rockette HE, et al. The genetic component of middle ear disease in the first 5 years of life. Arch Otolaryngol Head Neck Surg 2004; 130: 273-278.
10. Kvaerner KJ, Tambs K, Harris JR, Magnus P,. Distribution and heritability of recurrent ear infections. Ann Otol Rhinol Laryngol 1997; 106: 624-632.
11. Kvaerner KJ, Tambs K, Harris JR, Mair IW, Magnus P,. Otitis media: relationship to tonsillitis, sinusitis and atopic diseases. Int J Pediatr Otorhinolaryngol 1996; 35: 127-141.
12. Casselbrant ML, Mandel EM,. Genetic susceptibility to otitis media. Curr Opin Allergy Clin Immunol 2005; 5: 1-4.
13. Gebhart DE,. Tympanostomy tubes in the otitis media prone child. Laryngoscope 1981; 91: 849-866.
14. Bluestone CD, Klein JO. Otitis Media in Infants and Children. 3rd ed. Philadelphia, PA: Saunders; 2001.
15. Casselbrant ML, Mandel EM, Fall PA, et al. The heritability of otitis media: a twin and triplet study. JAMA 1999; 282: 2125-2130.
16. Casselbrant ML, Mandel EM, Jung J, et al. Otitis media: a genome-wide linkage scan with evidence of susceptibility loci within the 17q12 and 10q22.3 regions. BMC Med Genet 2009; 10: 85.
17. Chen WM, Allen EK, Mychaleckyj JC, et al. Significant linkage at chromosome 19q for otitis media with effusion and/or recurrent otitis media (COME/ROM). BMC Med Genet 2011; 12: 124.
18. Daly KA, Brown WM, Segade F, et al. Chronic and recurrent otitis media: a genome scan for susceptibility loci. Am J Hum Genet 2004; 75: 988-997.
19. Rye MS, Wiertsema SP, Scaman ES, et al. FBXO11, a regulator of the TGFbeta pathway, is associated with severe otitis media in Western Australian children. Genes Immun 2011; 12: 352-359.
20. McCormick DP, Grady JJ, Diego A, et al. Acute otitis media severity: Association with cytokine gene polymorphisms and other risk factors [published online ahead of print March 25, 2011 ]. Int J Pediatr Otorhinolaryngol. doi: 10.1016/j.ijporl.2011.02.021.
21. Ubell ML, Khampang P, Kerschner JE,. Mucin gene polymorphisms in otitis media patients. Laryngoscope 2010; 120: 132-138.
22. Alper CM, Winther B, Hendley JO, Doyle WJ,. Cytokine polymorphisms predict the frequency of otitis media as a complication of rhinovirus and RSV infections in children. Eur Arch Otorhinolaryngol 2009; 266: 199-205.
23. Segade F, Daly KA, Allred D, et al. Association of the FBXO11 gene with chronic otitis media with effusion and recurrent otitis media: the Minnesota COME/ROM Family Study. Arch Otolaryngol Head Neck Surg 2006; 132: 729-733.
24. Sale MM, Chen WM, Weeks DE, et al. Evaluation of 15 functional candidate genes for association with chronic otitis media with effusion and/or recurrent otitis media (COME/ROM). PLoS One 2011; 6 (8): e22297.
25. Emonts M, Veenhoven RH, Wiertsema SP, et al. Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. Pediatrics 2007; 120: 814-823.
26. Post JC,. Genetics of otitis media. Adv Otorhinolaryngol 2011; 70: 135-140.
27. Takeuchi K, Yagawa M, Ishinaga H, Kishioka C, Harada T, Majima Y,. Mucin gene expression in the effusions of otitis media with effusion. Int J Pediatr Otorhinolaryngol 2003; 67: 53-58.
28. Rye MS, Blackwell JM, Jamieson SE,. Genetic susceptibility to otitis media in childhood. Laryngoscope 2012; 122: 665-675.
29. Carroll SR, Zald PB, Soler ZM, Milczuk HA, Trune DR, MacArthur CJ,. Innate immunity gene single nucleotide polymorphisms and otitis media. Int J Pediatr Otorhinolaryngol 2012; 76: 976-979.
30. MacArthur CJ, Hefeneider SH, Kempton JB, Trune DR,. C3H/HeJ mouse model for spontaneous chronic otitis media. Laryngoscope 2006; 116: 1071-1079.
31. MacArthur CJ, Trune DR,. Mouse models of otitis media. Curr Opin Otolaryngol Head Neck Surg 2006; 14: 341-346.
32. Rosenfeld RM, Culpepper L, Doyle KJ, et al. Clinical practice guideline: otitis media with effusion. Otolaryngol Head Neck Surg 2004; 130 (5 suppl): S95-S118.
33. Gordon D, Haynes C, Blumenfeld J, Finch SJ,. PAWE-3D: visualizing power for association with error in case-control genetic studies of complex traits. Bioinformatics 2005; 21: 3935-3937.
34. Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA,. Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 2004; 74: 106-120.
35. International HapMap Consortium. A haplotype map of the human genome. Nature 2005; 437: 1299-1320.
36. Barrett JC, Fry B, Maller J, Daly MJ,. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265.
37. Aulchenko YS, Ripke S, Isaacs A, van Duijn CM,. GenABEL: an R library for genome-wide association analysis. Bioinformatics 2007; 23: 1294-1296.