Stroke alters respiratory burst in neutrophils and monocytes

Stroke

Volumn 45, Issue 3, 2014, Pages 794-800

  Ruhnau, Johanna ^a   Schulze, Karsten ^a   Gaida, Bernadette ^a   Langner, Sonke ^a   Kessler, Christof ^a   Broker, Barbara ^a   Dressel, Alexander ^a   Vogelgesang, Antje ^a  

^a UNIVERSITY MEDICINE GREIFSWALD   (Germany)

Author keywords

Brain ischemia; Granulocytes; Immunosuppression; Infection; Phagocytes; Respiratory burst; Stroke

Indexed keywords

ACETYLCHOLINE; DEFENSIN; METADRENALIN; STRESS HORMONE; HORMONE;

ADULT; AGED; ARTICLE; BACTERIAL INFECTION; BACTERICIDAL ACTIVITY; BRAIN ISCHEMIA; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; DEGRANULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GRANULOCYTE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MAJOR CLINICAL STUDY; MONOCYTE; NEUTROPHIL; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RESPIRATORY BURST; STROKE ASSOCIATED BACTERIAL INFECTION; STROKE INDUCED IMMUNE ALTERATION; VERY ELDERLY; BLOOD; BRAIN INFARCTION; CELL MOTION; CEREBROVASCULAR ACCIDENT; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; FIBRINOLYTIC THERAPY; FLOW CYTOMETRY; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; MALE; METABOLISM; MIDDLE AGED; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PHYSIOLOGY;

BRAIN ISCHEMIA; GRANULOCYTES; IMMUNOSUPPRESSION; INFECTION; PHAGOCYTES; RESPIRATORY BURST; STROKE;

ACETYLCHOLINE; ADULT; AGED; AGED, 80 AND OVER; CELL DEGRANULATION; CELL MOVEMENT; CEREBRAL INFARCTION; CHEMOTAXIS, LEUKOCYTE; DEFENSINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HORMONES; HUMANS; MALE; MIDDLE AGED; MONOCYTES; NEUTROPHILS; PHAGOCYTOSIS; RESPIRATORY BURST; STROKE; THROMBOLYTIC THERAPY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84899139957     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.003342     Document Type: Article

References (29)

1. Johnston KC, Li JY, Lyden PD, Hanson SK, Feasby TE, Adams RJ, et al. Medical and neurological complications of ischemic stroke: experience from the RANTTAS trial. RANTTAS Investigators. Stroke. 1998;29:447-453.
2. Hilker R, Poetter C, Findeisen N, Sobesky J, Jacobs A, Neveling M, et al. Nosocomial pneumonia after acute stroke: Implications for neurological intensive care medicine. Stroke. 2003;34:975-981.
3. Katan M, Elkind MS. Inflammatory and neuroendocrine biomarkers of prognosis after ischemic stroke. Expert Rev Neurother. 2011; 11:225-239.
4. Chamorro A, Urra X, Planas AM. Infection after acute ischemic stroke: A manifestation of brain-induced immunodepression. Stroke. 2007;38:1097-1103.
5. Vogelgesang A, Grunwald U, Langner S, Jack R, Broker BM, Kessler C, et al. Analysis of lymphocyte subsets in patients with stroke and their influence on infection after stroke. Stroke. 2008;39:237-241.
6. Vogelgesang A, Dressel A. Immunological consequences of ischemic stroke: Immunosuppression and autoimmunity. J Neuroimmunol. 2011;231:105-110.
7. Vogelgesang A, May VE, Grunwald U, Bakkeboe M, Langner S, Wallaschofski H, et al. Functional status of peripheral blood T-cells in ischemic stroke patients. PLoS One. 2010;5:e8718.
8. Klehmet J, Harms H, Richter M, Prass K, Volk HD, Dirnagl U, et al. Stroke-induced immunodepression and post-stroke infections: Lessons from the preventive antibacterial therapy in stroke trial. Neuroscience. 2009;158:1184-1193.
9. Urra X, Cervera A, Obach V, Climent N, Planas AM, Chamorro A. Monocytes are major players in the prognosis and risk of infection after acute stroke. Stroke. 2009;40:1262-1268.
10. Hug A, Liesz A, Muerle B, Zhou W, Ehrenheim J, Lorenz A, et al. Reduced efficacy of circulating costimulatory cells after focal cerebral ischemia. Stroke. 2011;42:3580-3586.
11. Urra X, Villamor N, Amaro S, Gómez-Choco M, Obach V, Oleaga L, et al. Monocyte subtypes predict clinical course and prognosis in human stroke. J Cereb Blood Flow Metab. 2009;29:994-1002.
12. Wong CH, Jenne CN, Lee WY, Leger C, Kubes P. Functional innervation of hepatic iNKT cells is immunosuppressive following stroke. Science. 2011;334:101-105.
13. Kuijpers T, Lutter R. Inflammation and repeated infections in CGD: Two sides of a coin. Cell Mol Ufe Sci. 2012;69:7-15.
14. Bowdish DM, Davidson DJ, Hancock RE. Immunomodulatory properties of defensins and cathelicidins. Curr Top Microbiol Immunol. 2006;306:27-66.
15. Mesa MA, Vasquez G. NETosis. Autoimmune Dis. 2013;2013:65-1497.
16. Wolach B, Gavrieli R, Roos D, Berger- Achituv S. Lessons learned from phagocytic function studies in a large cohort of patients with recurrent infections. J Clin Immunol. 2012;32:454-466.
17. Wolach B, Sazbon L, Gavrieli R, Broda A, Schlesinger M. Early immunological defects in comatose patients after acute brain injury. J Neurosurg. 2001;94:706-711.
18. Esparza B, Sanchez H, Ruiz M, Barranquero M, Sabino E, Merino F. Neutrophil function in elderly persons assessed by flow cytometry. Immunol Invest. 1996;25:185-190.
19. Seki Y, Sahara Y, Itoh E, Kawamura T. Suppressed neutrophil respiratory burst in patients with haemorrhagic stroke. J Clin Neurosci. 2010;17:187-190.
20. Molnar T, Peterfalvi A, Szereday L, Pusch G, Szapary L, Komoly S, et al. Deficient leucocyte antisedimentation is related to post-stroke infections and outcome. J Clin Pathol. 2008;61:1209-1213.
21. Campbell KA, Joseph SP, Whiting MJ, Doogue MP. The half-lives of plasma free metanephrines. Clin Endocrinol (Oxf). 2012;76:764-766.
22. Sangaletti S, Tripodo C, Chiodoni C, Guarnotta C, Cappetti B, Casalini P, et al. Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity. Blood. 2012;120:3007-3018.
23. Haeusler KG, Schmidt WU, Foehring F, Meisel C, Guenther C, Brunecker P, et al. Immune responses after acute ischemic stroke or myocardial infarction. Int J Cardiol. 2012;155:372-377.
24. Hug A, Dalpke A, Wieczorek N, Giese T, Lorenz A, Auf Tarth G, et al. Infarct volume is a major determiner of post-stroke immune cell function and susceptibility to infection. Stroke. 2009;40:3226-3232.
25. Chamorro A, Amaro S, Vargas M, Obach V, Cervera A, Gomez-Choco M, et al. Catecholamines, infection, and death in acute ischemic stroke. J Neurol Sci. 2007;252:29-35.
26. Prass K, Meisel C, Hoflich C, Braun J, Halle E, Wolf T, et al. Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke Thelper cell type 1-like immunostimulation. J Exp Med. 2003;198:725-736.
27. Walter U, Kolbaske S, Patejdl R, Steinhagen V, Abu-Mugheisib M, Grossmann A, et al. Insular stroke is associated with acute sympathetic hyperactivation and immunodepression. Eur J Neurol. 2013;20:153-159.
28. Harms H, Reimnitz P, Bohner G, Werich T, Klingebiel R, Meisel C, et al. Influence of stroke localization on autonomic activation, immunodepression, and post-stroke infection. Cerebrovasc Dis. 2011;32:552-560.
29. Kemmling A, Lev MH, Payabvash S, Betensky RA, Qian J, Masrur S, et al. Hospital acquired pneumonia is linked to right hemispheric peri-insular stroke. PLoS One. 2013;8:e71141.