Decreased dendritic cell numbers but increased TLR9-mediated interferon-alpha production in first degree relatives of type 1 diabetes patients

Clinical Immunology

Volumn 153, Issue 1, 2014, Pages 49-55

  Kayserova, Jana ^a   Vcelakova, Jana ^b   Stechova, Katerina ^b   Dudkova, Eva ^a   Hromadkova, Hana ^a   Sumnik, Zdenek ^b   Kolouskova, Stanislava ^b   Spisek, Radek ^a   Sediva, Anna ^a  

^a UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^b Sotio   (Czech Republic)

Author keywords

Dendritic cell ; Interferon alpha ; Type 1 diabetes

Indexed keywords

ALPHA INTERFERON; AUTOANTIBODY; CPG 2216; GLUTAMATE DECARBOXYLASE 65; HLA ANTIGEN CLASS 2; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; INSULIN; LOXORIBINE; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CELL COUNT; CHILD; CONTROLLED STUDY; CULTURE MEDIUM; DIABETIC PATIENT; FEMALE; FIRST DEGREE RELATIVE; GENETIC RISK; GENOTYPE; HAPLOTYPE; HIGH RISK POPULATION; HLA SYSTEM; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; IMMUNOSTIMULATION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; LOW RISK POPULATION; MAJOR CLINICAL STUDY; MALE; MYELOID DENDRITIC CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL;

DENDRITIC CELL;; INTERFERON-ALPHA;; TYPE 1 DIABETES;

ADOLESCENT; ADULT; CELL COUNT; CHILD; CHILD, PRESCHOOL; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; FAMILY; FEMALE; HUMANS; INTERFERON-ALPHA; LEUKOCYTES, MONONUCLEAR; LIGANDS; MALE; OLIGODEOXYRIBONUCLEOTIDES; TOLL-LIKE RECEPTOR 9; YOUNG ADULT;

EID: 84899135736     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2014.03.018     Document Type: Article

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