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Volumn 103, Issue , 2014, Pages 153-169

Quantitative proteomics reveals ER-α involvement in CD146-induced epithelial-mesenchymal transition in breast cancer cells

Author keywords

CD146; Epithelial mesenchymal transition; ER ; Proteome; SILAC; Triple negative breast cancer

Indexed keywords

AMINO ACID; CD146 ANTIGEN; CELL PROTEIN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; STABLE ISOTOPE; TRANSCRIPTION FACTOR SLUG; MCAM PROTEIN, HUMAN; MESSENGER RNA;

EID: 84899133324     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2014.03.033     Document Type: Article
Times cited : (20)

References (51)
  • 1
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery J.P., Acloque H., Huang R.Y., Nieto M.A. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139:871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 2
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
    • Polyak K., Weinberg R.A. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009, 9:265-273.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 3
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl A.K., Wilgenbus P., Dahl U., Semb H., Christofori G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 1998, 392:190-193.
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 4
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis
    • Yang J., Weinberg R.A. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 2008, 14:818-829.
    • (2008) Dev Cell , vol.14 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 5
    • 33845807351 scopus 로고    scopus 로고
    • Cell adhesion molecule L1 disrupts E-cadherin-containing adherens junctions and increases scattering and motility of MCF7 breast carcinoma cells
    • Shtutman M., Levina E., Ohouo P., Baig M., Roninson I.B. Cell adhesion molecule L1 disrupts E-cadherin-containing adherens junctions and increases scattering and motility of MCF7 breast carcinoma cells. Cancer Res 2006, 66:11370-11380.
    • (2006) Cancer Res , vol.66 , pp. 11370-11380
    • Shtutman, M.1    Levina, E.2    Ohouo, P.3    Baig, M.4    Roninson, I.B.5
  • 6
    • 84863012785 scopus 로고    scopus 로고
    • CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer
    • Zeng Q., Li W., Lu D., Wu Z., Duan H., Luo Y., et al. CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer. Proc Natl Acad Sci U S A 2012, 109:1127-1132.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 1127-1132
    • Zeng, Q.1    Li, W.2    Lu, D.3    Wu, Z.4    Duan, H.5    Luo, Y.6
  • 7
    • 0024791128 scopus 로고
    • MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily
    • Lehmann J.M., Riethmuller G., Johnson J.P. MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily. Proc Natl Acad Sci U S A 1989, 86:9891-9895.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 9891-9895
    • Lehmann, J.M.1    Riethmuller, G.2    Johnson, J.P.3
  • 8
    • 0038305607 scopus 로고    scopus 로고
    • A novel anti-CD146 monoclonal antibody, AA98, inhibits angiogenesis and tumor growth
    • Yan X., Lin Y., Yang D., Shen Y., Yuan M., Zhang Z., et al. A novel anti-CD146 monoclonal antibody, AA98, inhibits angiogenesis and tumor growth. Blood 2003, 102:184-191.
    • (2003) Blood , vol.102 , pp. 184-191
    • Yan, X.1    Lin, Y.2    Yang, D.3    Shen, Y.4    Yuan, M.5    Zhang, Z.6
  • 9
    • 84866343239 scopus 로고    scopus 로고
    • CD146 is a coreceptor for VEGFR-2 in tumor angiogenesis
    • Jiang T., Zhuang J., Duan H., Luo Y., Zeng Q., Fan K., et al. CD146 is a coreceptor for VEGFR-2 in tumor angiogenesis. Blood 2012, 120:2330-2339.
    • (2012) Blood , vol.120 , pp. 2330-2339
    • Jiang, T.1    Zhuang, J.2    Duan, H.3    Luo, Y.4    Zeng, Q.5    Fan, K.6
  • 11
    • 0035450627 scopus 로고    scopus 로고
    • Expression of a human cell adhesion molecule, MUC18, in prostate cancer cell lines and tissues
    • Wu G.J., Varma V.A., Wu M.W., Wang S.W., Qu P., Yang H., et al. Expression of a human cell adhesion molecule, MUC18, in prostate cancer cell lines and tissues. Prostate 2001, 48:305-315.
    • (2001) Prostate , vol.48 , pp. 305-315
    • Wu, G.J.1    Varma, V.A.2    Wu, M.W.3    Wang, S.W.4    Qu, P.5    Yang, H.6
  • 12
    • 84868116479 scopus 로고    scopus 로고
    • MCAM is a novel metastasis marker and regulates spreading, apoptosis and invasion of ovarian cancer cells
    • Wu Z., Li J., Yang X., Wang Y., Yu Y., Ye J., et al. MCAM is a novel metastasis marker and regulates spreading, apoptosis and invasion of ovarian cancer cells. Tumour Biol 2012, 33:1619-1628.
    • (2012) Tumour Biol , vol.33 , pp. 1619-1628
    • Wu, Z.1    Li, J.2    Yang, X.3    Wang, Y.4    Yu, Y.5    Ye, J.6
  • 14
  • 15
    • 84861566371 scopus 로고    scopus 로고
    • CD146 expression correlates with epithelial-mesenchymal transition markers and a poor prognosis in gastric cancer
    • Liu W.F., Ji S.R., Sun J.J., Zhang Y., Liu Z.Y., Liang A.B., et al. CD146 expression correlates with epithelial-mesenchymal transition markers and a poor prognosis in gastric cancer. Int J Mol Sci 2012, 13:6399-6406.
    • (2012) Int J Mol Sci , vol.13 , pp. 6399-6406
    • Liu, W.F.1    Ji, S.R.2    Sun, J.J.3    Zhang, Y.4    Liu, Z.Y.5    Liang, A.B.6
  • 16
    • 60549110525 scopus 로고    scopus 로고
    • Identification of MCAM/CD146 as the target antigen of a human monoclonal antibody that recognizes both epithelioid and sarcomatoid types of mesothelioma
    • Bidlingmaier S., He J., Wang Y., An F., Feng J., Barbone D., et al. Identification of MCAM/CD146 as the target antigen of a human monoclonal antibody that recognizes both epithelioid and sarcomatoid types of mesothelioma. Cancer Res 2009, 69:1570-1577.
    • (2009) Cancer Res , vol.69 , pp. 1570-1577
    • Bidlingmaier, S.1    He, J.2    Wang, Y.3    An, F.4    Feng, J.5    Barbone, D.6
  • 17
    • 78049452833 scopus 로고    scopus 로고
    • Immunocytochemistry of CD146 is useful to discriminate between malignant pleural mesothelioma and reactive mesothelium
    • Sato A., Torii I., Okamura Y., Yamamoto T., Nishigami T., Kataoka T.R., et al. Immunocytochemistry of CD146 is useful to discriminate between malignant pleural mesothelioma and reactive mesothelium. Mod Pathol 2010, 23:1458-1466.
    • (2010) Mod Pathol , vol.23 , pp. 1458-1466
    • Sato, A.1    Torii, I.2    Okamura, Y.3    Yamamoto, T.4    Nishigami, T.5    Kataoka, T.R.6
  • 18
    • 79954610473 scopus 로고    scopus 로고
    • Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells
    • Zeng G.F., Cai S.X., Wu G.J. Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells. BMC Cancer 2011, 11:113.
    • (2011) BMC Cancer , vol.11 , pp. 113
    • Zeng, G.F.1    Cai, S.X.2    Wu, G.J.3
  • 19
    • 67549149803 scopus 로고    scopus 로고
    • CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines
    • Zabouo G., Imbert A.M., Jacquemier J., Finetti P., Moreau T., Esterni B., et al. CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines. Breast Cancer Res 2009, 11:R1.
    • (2009) Breast Cancer Res , vol.11
    • Zabouo, G.1    Imbert, A.M.2    Jacquemier, J.3    Finetti, P.4    Moreau, T.5    Esterni, B.6
  • 20
    • 0035106351 scopus 로고    scopus 로고
    • Large-scale analysis of the yeast proteome by multidimensional protein identification technology
    • Washburn M.P., Wolters D., Yates J.R. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat Biotechnol 2001, 19:242-247.
    • (2001) Nat Biotechnol , vol.19 , pp. 242-247
    • Washburn, M.P.1    Wolters, D.2    Yates, J.R.3
  • 21
    • 84934435370 scopus 로고    scopus 로고
    • Analysis of organelles by on-line two-dimensional liquid chromatography-tandem mass spectrometry
    • Romijn E.P., Yates J.R. Analysis of organelles by on-line two-dimensional liquid chromatography-tandem mass spectrometry. Methods Mol Biol 2008, 432:1-16.
    • (2008) Methods Mol Biol , vol.432 , pp. 1-16
    • Romijn, E.P.1    Yates, J.R.2
  • 22
    • 79951604998 scopus 로고    scopus 로고
    • Differentially expressed protein profile of renal tubule cell stimulated by elevated uric acid using SILAC coupled to LC-MS
    • Quan H., Peng X., Liu S., Bo F., Yang L., Huang Z., et al. Differentially expressed protein profile of renal tubule cell stimulated by elevated uric acid using SILAC coupled to LC-MS. Cell Physiol Biochem 2011, 27:91-98.
    • (2011) Cell Physiol Biochem , vol.27 , pp. 91-98
    • Quan, H.1    Peng, X.2    Liu, S.3    Bo, F.4    Yang, L.5    Huang, Z.6
  • 23
    • 57449099865 scopus 로고    scopus 로고
    • MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
    • Cox J., Mann M. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol 2008, 26:1367-1372.
    • (2008) Nat Biotechnol , vol.26 , pp. 1367-1372
    • Cox, J.1    Mann, M.2
  • 24
    • 84855946358 scopus 로고    scopus 로고
    • Recognition of CD146 as an ERM-binding protein offers novel mechanisms for melanoma cell migration
    • Luo Y., Zheng C., Zhang J., Lu D., Zhuang J., Xing S., et al. Recognition of CD146 as an ERM-binding protein offers novel mechanisms for melanoma cell migration. Oncogene 2012, 31:306-321.
    • (2012) Oncogene , vol.31 , pp. 306-321
    • Luo, Y.1    Zheng, C.2    Zhang, J.3    Lu, D.4    Zhuang, J.5    Xing, S.6
  • 25
    • 84869091854 scopus 로고    scopus 로고
    • Regulation of IMP3 by EGFR signaling and repression by ERbeta: implications for triple-negative breast cancer
    • Samanta S., Sharma V.M., Khan A., Mercurio A.M. Regulation of IMP3 by EGFR signaling and repression by ERbeta: implications for triple-negative breast cancer. Oncogene 2012, 31:4689-4697.
    • (2012) Oncogene , vol.31 , pp. 4689-4697
    • Samanta, S.1    Sharma, V.M.2    Khan, A.3    Mercurio, A.M.4
  • 26
    • 33645751864 scopus 로고    scopus 로고
    • Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients
    • Innes H.E., Liu D., Barraclough R., Davies M.P., O'Neill P.A., Platt-Higgins A., et al. Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients. Br J Cancer 2006, 94:1057-1065.
    • (2006) Br J Cancer , vol.94 , pp. 1057-1065
    • Innes, H.E.1    Liu, D.2    Barraclough, R.3    Davies, M.P.4    O'Neill, P.A.5    Platt-Higgins, A.6
  • 29
    • 33845192140 scopus 로고    scopus 로고
    • Anti-CD146 monoclonal antibody AA98 inhibits angiogenesis via suppression of nuclear factor-kappaB activation
    • Bu P., Gao L., Zhuang J., Feng J., Yang D., Yan X. Anti-CD146 monoclonal antibody AA98 inhibits angiogenesis via suppression of nuclear factor-kappaB activation. Mol Cancer Ther 2006, 5:2872-2878.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2872-2878
    • Bu, P.1    Gao, L.2    Zhuang, J.3    Feng, J.4    Yang, D.5    Yan, X.6
  • 30
    • 70349299880 scopus 로고    scopus 로고
    • Endothelial CD146 is required for in vitro tumor-induced angiogenesis: the role of a disulfide bond in signaling and dimerization
    • Zheng C., Qiu Y., Zeng Q., Zhang Y., Lu D., Yang D., et al. Endothelial CD146 is required for in vitro tumor-induced angiogenesis: the role of a disulfide bond in signaling and dimerization. Int J Biochem Cell Biol 2009, 41:2163-2172.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 2163-2172
    • Zheng, C.1    Qiu, Y.2    Zeng, Q.3    Zhang, Y.4    Lu, D.5    Yang, D.6
  • 31
    • 0037453706 scopus 로고    scopus 로고
    • MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer
    • Fujita N., Jaye D.L., Kajita M., Geigerman C., Moreno C.S., Wade P.A. MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer. Cell 2003, 113:207-219.
    • (2003) Cell , vol.113 , pp. 207-219
    • Fujita, N.1    Jaye, D.L.2    Kajita, M.3    Geigerman, C.4    Moreno, C.S.5    Wade, P.A.6
  • 32
    • 76149129714 scopus 로고    scopus 로고
    • Extracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration
    • Mathias R.A., Chen Y.S., Wang B., Ji H., Kapp E.A., Moritz R.L., et al. Extracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration. J Proteome Res 2010, 9:1007-1019.
    • (2010) J Proteome Res , vol.9 , pp. 1007-1019
    • Mathias, R.A.1    Chen, Y.S.2    Wang, B.3    Ji, H.4    Kapp, E.A.5    Moritz, R.L.6
  • 33
    • 69349102421 scopus 로고    scopus 로고
    • Towards understanding epithelial-mesenchymal transition: a proteomics perspective
    • Mathias R.A., Simpson R.J. Towards understanding epithelial-mesenchymal transition: a proteomics perspective. Biochim Biophys Acta 2009, 1794:1325-1331.
    • (2009) Biochim Biophys Acta , vol.1794 , pp. 1325-1331
    • Mathias, R.A.1    Simpson, R.J.2
  • 34
    • 79251474948 scopus 로고    scopus 로고
    • Subcellular proteomics revealed the epithelial-mesenchymal transition phenotype in lung cancer
    • Li L.P., Lu C.H., Chen Z.P., Ge F., Wang T., Wang W., et al. Subcellular proteomics revealed the epithelial-mesenchymal transition phenotype in lung cancer. Proteomics 2011, 11:429-439.
    • (2011) Proteomics , vol.11 , pp. 429-439
    • Li, L.P.1    Lu, C.H.2    Chen, Z.P.3    Ge, F.4    Wang, T.5    Wang, W.6
  • 35
    • 63849257577 scopus 로고    scopus 로고
    • Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype
    • Zhou C., Nitschke A.M., Xiong W., Zhang Q., Tang Y., Bloch M., et al. Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype. Breast Cancer Res 2008, 10:R105.
    • (2008) Breast Cancer Res , vol.10
    • Zhou, C.1    Nitschke, A.M.2    Xiong, W.3    Zhang, Q.4    Tang, Y.5    Bloch, M.6
  • 36
    • 79952679115 scopus 로고    scopus 로고
    • Proteomics profiling of Madin-Darby canine kidney plasma membranes reveals Wnt-5a involvement during oncogenic H-Ras/TGF-beta-mediated epithelial-mesenchymal transition
    • [M110 001131]
    • Chen Y.S., Mathias R.A., Mathivanan S., Kapp E.A., Moritz R.L., Zhu H.J., et al. Proteomics profiling of Madin-Darby canine kidney plasma membranes reveals Wnt-5a involvement during oncogenic H-Ras/TGF-beta-mediated epithelial-mesenchymal transition. Mol Cell Proteomics 2011, 10. [M110 001131].
    • (2011) Mol Cell Proteomics , vol.10
    • Chen, Y.S.1    Mathias, R.A.2    Mathivanan, S.3    Kapp, E.A.4    Moritz, R.L.5    Zhu, H.J.6
  • 38
    • 79952621557 scopus 로고    scopus 로고
    • Estrogen and progesterone in normal mammary gland development and in cancer
    • Stingl J. Estrogen and progesterone in normal mammary gland development and in cancer. Horm Cancer 2011, 2:85-90.
    • (2011) Horm Cancer , vol.2 , pp. 85-90
    • Stingl, J.1
  • 39
    • 77949423072 scopus 로고    scopus 로고
    • ERalpha signaling through slug regulates E-cadherin and EMT
    • Ye Y., Xiao Y., Wang W., Yearsley K., Gao J.X., Shetuni B., et al. ERalpha signaling through slug regulates E-cadherin and EMT. Oncogene 2010, 29:1451-1462.
    • (2010) Oncogene , vol.29 , pp. 1451-1462
    • Ye, Y.1    Xiao, Y.2    Wang, W.3    Yearsley, K.4    Gao, J.X.5    Shetuni, B.6
  • 40
    • 67650034863 scopus 로고    scopus 로고
    • RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1
    • Wang X., Belguise K., O'Neill C.F., Sanchez-Morgan N., Romagnoli M., Eddy S.F., et al. RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1. Mol Cell Biol 2009, 29:3832-3844.
    • (2009) Mol Cell Biol , vol.29 , pp. 3832-3844
    • Wang, X.1    Belguise, K.2    O'Neill, C.F.3    Sanchez-Morgan, N.4    Romagnoli, M.5    Eddy, S.F.6
  • 41
    • 0035904395 scopus 로고    scopus 로고
    • Molecular biology of HMGA proteins: hubs of nuclear function
    • Reeves R. Molecular biology of HMGA proteins: hubs of nuclear function. Gene 2001, 277:63-81.
    • (2001) Gene , vol.277 , pp. 63-81
    • Reeves, R.1
  • 42
    • 36849078711 scopus 로고    scopus 로고
    • Let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • Yu F., Yao H., Zhu P., Zhang X., Pan Q., Gong C., et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007, 131:1109-1123.
    • (2007) Cell , vol.131 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3    Zhang, X.4    Pan, Q.5    Gong, C.6
  • 44
    • 2442681777 scopus 로고    scopus 로고
    • Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis
    • Mao Y.W., Liu J.P., Xiang H., Li D.W. Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis. Cell Death Differ 2004, 11:512-526.
    • (2004) Cell Death Differ , vol.11 , pp. 512-526
    • Mao, Y.W.1    Liu, J.P.2    Xiang, H.3    Li, D.W.4
  • 45
    • 33846297971 scopus 로고    scopus 로고
    • Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis
    • Liu S., Li J., Tao Y., Xiao X. Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis. Biochem Biophys Res Commun 2007, 354:109-114.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 109-114
    • Liu, S.1    Li, J.2    Tao, Y.3    Xiao, X.4
  • 46
    • 0037422859 scopus 로고    scopus 로고
    • Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis
    • Morrison L.E., Hoover H.E., Thuerauf D.J., Glembotski C.C. Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis. Circ Res 2003, 92:203-211.
    • (2003) Circ Res , vol.92 , pp. 203-211
    • Morrison, L.E.1    Hoover, H.E.2    Thuerauf, D.J.3    Glembotski, C.C.4
  • 47
    • 54249092318 scopus 로고    scopus 로고
    • Untangling the glutamate dehydrogenase allosteric nightmare
    • Smith T.J., Stanley C.A. Untangling the glutamate dehydrogenase allosteric nightmare. Trends Biochem Sci 2008, 33:557-564.
    • (2008) Trends Biochem Sci , vol.33 , pp. 557-564
    • Smith, T.J.1    Stanley, C.A.2
  • 48
    • 70350217425 scopus 로고    scopus 로고
    • Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling
    • Yang C., Sudderth J., Dang T., Bachoo R.M., McDonald J.G., DeBerardinis R.J. Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling. Cancer Res 2009, 69:7986-7993.
    • (2009) Cancer Res , vol.69 , pp. 7986-7993
    • Yang, C.1    Sudderth, J.2    Dang, T.3    Bachoo, R.M.4    McDonald, J.G.5    DeBerardinis, R.J.6
  • 49
    • 50149097983 scopus 로고    scopus 로고
    • Hypoxia, HIF1 and glucose metabolism in the solid tumour
    • Denko N.C. Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat Rev Cancer 2008, 8:705-713.
    • (2008) Nat Rev Cancer , vol.8 , pp. 705-713
    • Denko, N.C.1
  • 50
    • 33947724515 scopus 로고    scopus 로고
    • HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
    • Fukuda R., Zhang H., Kim J.W., Shimoda L., Dang C.V., Semenza G.L. HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell 2007, 129:111-122.
    • (2007) Cell , vol.129 , pp. 111-122
    • Fukuda, R.1    Zhang, H.2    Kim, J.W.3    Shimoda, L.4    Dang, C.V.5    Semenza, G.L.6
  • 51
    • 70249123890 scopus 로고    scopus 로고
    • Biology, metastatic patterns, and treatment of patients with triple-negative breast cancer
    • Anders C.K., Carey L.A. Biology, metastatic patterns, and treatment of patients with triple-negative breast cancer. Clin Breast Cancer 2009, 9(Suppl. 2):S73-S81.
    • (2009) Clin Breast Cancer , vol.9 , Issue.SUPPL. 2
    • Anders, C.K.1    Carey, L.A.2


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