Development of novel nanoparticle for bone cancer

Journal of Biomedical Nanotechnology

Volumn 10, Issue 7, 2014, Pages 1242-1248

  De Carvalho Patricio, Beatriz Ferreira ^a,b   De Souza Albernaz, Marta ^b   Sarcinelli, Michelle Alvares ^b   De Carvalho, Samira Marques ^c   Santos Oliveira, Ralph ^b   Weissmüller, Gilberto ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b Laboratory of Nanoradiopharmaceuticals   (Brazil)

^c INSTITUTO DE RADIOPROTEÇÃO E DOSIMETRIA   (Brazil)

Author keywords

AFM; In vivo biodistribution; Nanoparticle

Indexed keywords

ATOMIC FORCE MICROSCOPY; BONE; EMULSIFICATION; PATHOLOGY; PATIENT MONITORING; POLYMERS;

AFM; DOUBLE EMULSION-SOLVENT EVAPORATION; IN-VIVO; OPTIMAL TREATMENT; PHARMACEUTICAL FORMULATION; POLYMERIC NANOPARTICLES; PROLONGED RELEASE; TARGETED DELIVERY;

NANOPARTICLES;

ETHYLENEDIAMINE TETRAKIS(METHYLENEPHOSPHONIC ACID); NANOPARTICLE; POLYVINYL ALCOHOL; SAMARIUM 153; TECHNETIUM 99M; LACTIC ACID; ORGANOPHOSPHORUS COMPOUND; POLYLACTIC ACID; POLYMER; TECHNETIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOMIC FORCE MICROSCOPY; BONE CANCER; BONE TISSUE; CANCER SURVIVAL; CONTROLLED STUDY; DRUG DISTRIBUTION; EMULSION; EVAPORATION; IN VIVO STUDY; ISOTOPE LABELING; MALE; NONHUMAN; PARTICLE SIZE; RADIOACTIVITY; RAT; ANIMAL; BONE NEOPLASMS; CHEMISTRY; INJECTION; SCINTISCANNING; STAINING; TISSUE DISTRIBUTION; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; BONE NEOPLASMS; INJECTIONS; LACTIC ACID; NANOPARTICLES; ORGANOPHOSPHORUS COMPOUNDS; POLYMERS; POLYVINYL ALCOHOL; RATS; RATS, WISTAR; STAINING AND LABELING; TECHNETIUM; TISSUE DISTRIBUTION;

EID: 84899112288     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2014.1812     Document Type: Article

References (18)

1. M. D. S. Albernaz, B. F. D. C. Patricio, G. Weissmuller, F. Reynaud, T. Adamsen, and R. Santos-Oliveira, Polymeric nanoparticles of FMISO: are nano-radiopharmaceuticals better than conventional ones? Curr. Radiopharm. 5, 336 (2012).
2. K. Cho, X. Wang, S. Nie, Z. Chen, and D. M. Shin, Therapeutic nanoparticles for drug delivery in cancer. Clinical Cancer Research 14, 1310 (2008).
3. M. E. Davis, Z. G. Chen, and D. M. Shin, Nanoparticle therapeutics: An emerging treatment modality for cancer. Nat. Rev. Drug. Discov. 7, 771 (2008).
4. M. C. Garnett and P. Kallinteri, Nanomedicines and Nanotoxicology, Some Physiological Principles, Occupational Medicine Oxford, England (2006), Vol. 56, p. 307.
5. R. M. Mainardes, N. M. Khalil, and M. P. D. Gremião, Intranasal delivery of zidovudine by PLA and PLA-PEG blend nanoparticles. Int. J. Pharm. 395, 266 (2010).
6. W. Meohas, D. Probstner, R. A. T. Vasconcellos, A. C. D. S. Lopes, J. F. N. Rezende, and N. J. Fiod, Metástase óssea: revisão da literatura. Revista Brasileira de Cancerologia 51, 43 (2005).
7. C. E. Mora-Huertas, H. Fessi, and A. Elaissari, Polymer-based nanocapsules for drug delivery. Int. J. Pharm. 385, 113 (2010).
8. V. J. Morris, A. R. Kirby, and A. P. Gunning, Atomic Force Microscopy for Biologists, Imperial College Pr, Londres (2009).
9. F. M. Paes, V. Ernani, P. Hosein, and A. N. Serafini, Radiopharmaceuticals: When and how to use them to treat metastatic bone pain. J. Supportive Oncology 9, 197 (2011).
10. F. M. Paes and A. N. Serafini, Systemic metabolic radiopharmaceutical therapy in the treatment of metastatic bone pain. Seminars in Nuclear Medicine 40, 89 (2010).
11. N. Pandit-Taskar, M. Batraki, and C. R. Divgi, Radiopharmaceutical therapy for palliation of bone pain from osseous metastases. Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine 45, 1358 (2004).
12. L. A. Passeri, M. B. Bértolo, and A. Abuabara, Bisphosphonate-related osteonecrosis of the jaws. Revista brasileira de reumatologia 51, 401 (2011).
13. B. F. D. C. Patricio, M. H. M. Lima-Ribeiro, M. T. D. S. Correia, A. M. D. A. Carneiro-Leão, M. D. S. Albernaz, T. Barboza, S. A. L. de Souza, and R. Santos-Oliveira, Radiolabeling of cramoll: Evaluation of the biodistribution. International Journal of Peptides 1, 4 (2011).
14. G. D. Roodman, Mechanisms of bone metastasis. Discovery Medicine 4, 144 (2004).
15. L. T. Sa, S. M. D. E. Albernaz, B. F. Patricio, M. V. Falcao, Jr, B. F. Coelho, A. Bordim, J. C. Almeida, and R. Santos-Oliveira, Biodistribution of nanoparticles: Initial considerations. J. Pharm. Biomed. Anal. 70, 602 (2012).
16. G. B. Saha, Fundamentals of Nuclear Pharmacy, Springer Verlag, Nova Iorque (2010).
17. H. S. Smith, Painful osseous metastases. Pain Physician 14, E373 (2011).
18. C. Vauthier and K. Bouchemal, Methods for the preparation and manufacture of polymeric nanoparticles. Pharm. Res. 26, 1025 (2009).