Improvements in left ventricular hypertrophy and diastolic function following renal denervation: Effects beyond blood pressure and heart rate reduction

Journal of the American College of Cardiology

Volumn 63, Issue 18, 2014, Pages 1916-1923

  Schirmer, Stephan H ^a   Sayed, Marwa M Y A ^a   Reil, Jan Christian ^a   Ukena, Christian ^a   Linz, Dominik ^a   Kindermann, Michael ^a   Laufs, Ulrich ^a   Mahfoud, Felix ^a   Böhm, Michael ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

echocardiography; heart rate; left ventricular hypertrophy; renal denervation; resistant hypertension

Indexed keywords

ADULT; ARTICLE; BLOOD VESSEL COMPLIANCE; DIASTOLE; FEMALE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE SIZE; HEART MUSCLE RELAXATION; HEART RATE; HUMAN; KIDNEY DENERVATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RESISTANT HYPERTENSION; SYSTOLIC BLOOD PRESSURE; TRANSTHORACIC ECHOCARDIOGRAPHY; TREATMENT OUTCOME;

ECHOCARDIOGRAPHY; HEART RATE; LEFT VENTRICULAR HYPERTROPHY; RENAL DENERVATION; RESISTANT HYPERTENSION;

AGED; BLOOD PRESSURE; DIASTOLE; FEMALE; FOLLOW-UP STUDIES; HEART RATE; HUMANS; HYPERTROPHY, LEFT VENTRICULAR; KIDNEY; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SINGLE-BLIND METHOD; SYMPATHECTOMY; TREATMENT OUTCOME;

EID: 84899105395     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.10.073     Document Type: Article

References (39)

1. D. Levy, M.G. Larson, R.S. Vasan, W.B. Kannel, and K.K. Ho The progression from hypertension to congestive heart failure JAMA 275 1996 1557 1562
2. B. Dahlöf, K. Pennert, and L. Hansson Reversal of left ventricular hypertrophy in hypertensive patients. A metaanalysis of 109 treatment studies Am J Hypertens 5 1992 95 110
3. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) JAMA 288 2002 2981 2997
4. H. Moreno, and D.A. Calhoun True resistant hypertension: definition and prevalence J Hypertens 30 2012 2241 2242
5. Symplicity HTN-2 Investigators, M.D. Esler, and H. Krum et al. Renal sympathetic denervation in patients with treatment-resistant hypertension (the Symplicity HTN-2 trial): a randomised controlled trial Lancet 376 2010 1903 1909
6. C. Ukena, F. Mahfoud, and A. Spies et al. Effects of renal sympathetic denervation on heart rate and atrioventricular conduction in patients with resistant hypertension Int J Cardiol 167 2013 2846 2851
7. F. Mahfoud, T.F. Lüscher, and B. Andersson et al. Expert consensus document from the European Society of Cardiology on catheter-based renal denervation Eur Heart J 34 2013 2149 2157
8. P.M. Okin, S.E. Kjeldsen, and S. Julius et al. All-cause and cardiovascular mortality in relation to changing heart rate during treatment of hypertensive patients with electrocardiographic left ventricular hypertrophy Eur Heart J 31 2010 2271 2279
9. M. Böhm, K. Swedberg, and M. Komajda et al. Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial Lancet 376 2010 886 894
10. J.-C. Tardif, E. O'Meara, and M. Komajda et al. Effects of selective heart rate reduction with ivabradine on left ventricular remodelling and function: results from the SHIFT echocardiography substudy Eur Heart J 32 2011 2507 2515
11. K. Swedberg, M. Komajda, and M. Böhm et al. Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study Lancet 176 2010 875 885
12. M.C. Brandt, F. Mahfoud, and S. Reda et al. Renal sympathetic denervation reduces left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension J Am Coll Cardiol 59 2012 901 909
13. F. Mahfoud, C. Ukena, and R.E. Schmieder et al. Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension Circulation 128 2013 132 140
14. R.M. Lang, M. Bierig, and R.B. Devereux et al. Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology J Am Soc Echocardiogr 18 2005 1440 1463
15. R.B. Devereux, D.R. Alonso, and E.M. Lutas et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings Am J Cardiol 57 1986 450 458
16. R.D. Mosteller Simplified calculation of body-surface area N Engl J Med 317 1987 1098
17. S.F. Nagueh, C.P. Appleton, and T.C. Gillebert et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography Eur J Echocardiogr 10 2009 165 193
18. W. Grossman, D. Jones, and L.P. McLaurin Wall stress and patterns of hypertrophy in the human left ventricle J Clin Invest 56 1975 56 64
19. N. Reichek, J. Wilson, M. St. John Sutton, T.A. Plappert, S. Goldberg, and J.W. Hirshfeld Noninvasive determination of left ventricular end-systolic stress: validation of the method and initial application Circulation 65 1982 99 108
20. S.D. Colan, K.M. Borow, and A. Neumann Left ventricular end-systolic wall stress-velocity of fiber shortening relation: a load-independent index of myocardial contractility J Am Coll Cardiol 4 1984 715 724
21. M. Kindermann, U. Seeland, P. Ruhnke, M. Böhm, and C. Maack Functional effects of beta(1)-adrenoceptor polymorphisms on the hemodynamic response to dobutamine with and without beta-blocker administration Clin Res Cardiol 100 2011 129 137
22. F. Mahfoud, B. Cremers, and J. Janker et al. Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension Hypertension 60 2012 419 424
23. A.R. De Caterina, and A.M. Leone Why beta-blockers should not be used as first choice in uncomplicated hypertension Am J Cardiol 105 2010 1433 1438
24. A.B. Miller, N. Reichek, and M. St. John Sutton et al. Importance of blood pressure control in left ventricular mass regression J Am Soc Hypertens 4 2010 302 310
25. M. Böhm, M. Castellano, E. Agabiti-Rosei, M. Flesch, M. Paul, and E. Erdmann Dose-dependent dissociation of ACE-inhibitor effects on blood pressure, cardiac hypertrophy, and beta-adrenergic signal transduction Circulation 92 1995 3006 3013
26. R.B. Devereux, B. Dahlöf, and E. Gerdts et al. Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial Circulation 110 2004 1456 1462
27. J. Burns, S.G. Ball, G. Worthy, A.D. Struthers, D.A. Mary, and J.P. Greenwood Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance J Hypertens 30 2012 2039 2046
28. J. Yeboah, C.J. Rodriguez, and B. Stacey et al. Prognosis of individuals with asymptomatic left ventricular systolic dysfunction in the Multi-Ethnic Study of Atherosclerosis (MESA) Circulation 126 2012 2713 2719
29. P.M. Okin, R.B. Devereux, and S. Jern et al. Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events JAMA 292 2004 2343 2349
30. S. Perlini, G. Palladini, and I. Ferrero et al. Sympathectomy or doxazosin, but not propranolol, blunt myocardial interstitial fibrosis in pressure-overload hypertrophy Hypertension 46 2005 1213 1218
31. D. Hering, E.A. Lambert, and P. Marusic et al. Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension Hypertension 61 2013 457 464
32. H. Krum, M. Schlaich, and R. Whitbourn et al. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study Lancet 373 2009 1275 1281
33. K. Hanada, K. Asari, M. Saito, J. Kawana, M. Mita, and H. Ogata Comparison of pharmacodynamics between carvedilol and metoprolol in rats with isoproterenol-induced cardiac hypertrophy: effects of carvedilol enantiomers Eur J Pharmacol 589 2008 194 200
34. M. Metra, C. Torp-Pedersen, and K. Swedberg et al. Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial Eur Heart J 26 2005 2259 2268
35. J.C. Reil, F. Custodis, and K. Swedberg et al. Heart rate reduction in cardiovascular disease and therapy Clin Res Cardiol 100 2011 11 19
36. P. Germain, G. Roul, B. Kastler, J.M. Mossard, P. Bareiss, and A. Sacrez Inter-study variability in left ventricular mass measurement. Comparison between M-mode echography and MRI Eur Heart J 13 1992 1011 1019
37. F. Mahfoud, D. Teller, and D. Urban et al. Catheter-based renal denervation reduces left ventricular mass in patients with resistant hypertension - results from a multicenter CMR-study (abstr) Circulation 126 2012 A18179
38. S.R. Ommen, R.A. Nishimura, and C.P. Appleton et al. Clinical utility of Doppler echocardiography and tissue Doppler imaging in the estimation of left ventricular filling pressures: a comparative simultaneous Doppler- catheterization study Circulation 102 2000 1788 1794
39. A.T. Burns, K.A. Connelly, and A. La Gerche et al. Effect of heart rate on tissue Doppler measures of diastolic function Echocardiography 24 2007 697 701