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Volumn 44, Issue 5, 2014, Pages 1589-1598

Prostate cancer: Prognostic significance of the association of heterogeneous nuclear ribonucleoprotein K and androgen receptor expression

Author keywords

Androgen receptor; Diagnostic and prognostic biomarkers; Heterogeneous nuclear ribonucleoprotein K; Immunohistochemistry; Prognosis; Prostate cancer

Indexed keywords

ANDROGEN RECEPTOR; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; MITOGEN ACTIVATED PROTEIN KINASE; PROSTATE SPECIFIC ANTIGEN;

EID: 84899094362     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2345     Document Type: Article
Times cited : (23)

References (48)
  • 2
    • 0035058774 scopus 로고    scopus 로고
    • Preoperative serum prostate-specific antigen (PSA) below 10 μg/l predicts neither the presence of prostate cancer nor the rate of postoperative PSA failure
    • Stamey TA: Preoperative serum prostate-specific antigen (PSA) below 10 μg/l predicts neither the presence of prostate cancer nor the rate of postoperative PSA failure. Clin Chem 47: 631-634, 2001.
    • (2001) Clin Chem , vol.47 , pp. 631-634
    • Stamey, T.A.1
  • 4
    • 0030989397 scopus 로고    scopus 로고
    • Percentage carcinoma as a measure of prostatic tumor size in radical prostatectomy tissues
    • Humphrey PA and Vollmer RT: Percentage carcinoma as a measure of prostatic tumor size in radical prostatectomy tissues. Mod Pathol 10: 326-333, 1997. (Pubitemid 27228880)
    • (1997) Modern Pathology , vol.10 , Issue.4 , pp. 326-333
    • Humphrey, P.A.1    Vollmer, R.T.2
  • 5
    • 0032893572 scopus 로고    scopus 로고
    • Should Gleason score 7 prostate cancerbe considered a unique grade category?
    • DOI 10.1016/S0090-4295(98)00479-8, PII S0090429598004798
    • Tefilli MV, Gheiler EL, Tiguert R, Sakr W, Grignon DJ, Banerjee M, Pontes JE and Wood DP Jr: Should Gleason score 7 prostate cancer be considered a unique grade category? Urology 53: 372-377, 1999. (Pubitemid 29063329)
    • (1999) Urology , vol.53 , Issue.2 , pp. 372-377
    • Tefilli, M.V.1    Gheiler, E.L.2    Tiguert, R.3    Sakr, W.4    Grignon, D.J.5    Banerjee, M.6    Pontes, J.E.7    Wood Jr., D.P.8
  • 6
    • 20444421889 scopus 로고    scopus 로고
    • Gleason grading of prostate cancer in needle biopsies or radical prostatectomy specimens: Contemporary approach, current clinical significance and sources of pathology discrepancies
    • DOI 10.1111/j.1464-410X.2005.05540.x
    • Montironi R, Mazzuccheli R, Scarpelli M, Lopez-Beltran A, Fellegara G and Algaba F: Gleason grading of prostate cancer in needle biopsies or radical prostatectomy specimens: contemporary approach, current clinical significance and sources of pathology discrepancies. BJU Int 95: 1146-1152, 2005. (Pubitemid 40799472)
    • (2005) BJU International , vol.95 , Issue.8 , pp. 1146-1152
    • Montironi, R.1    Mazzuccheli, R.2    Scarpelli, M.3    Lopez-Beltran, A.4    Fellegara, G.5    Algaba, F.6
  • 9
    • 2942623743 scopus 로고    scopus 로고
    • hnRNP K: One protein multiple processes
    • DOI 10.1002/bies.20048
    • Bomsztyk K, Denisenko O and Ostrowski J: hnRNP K: one protein multiple processes. Bioessays 26: 629-638, 2004. (Pubitemid 38758340)
    • (2004) BioEssays , vol.26 , Issue.6 , pp. 629-638
    • Bomsztyk, K.1    Denisenko, O.2    Ostrowski, J.3
  • 10
    • 0242490528 scopus 로고    scopus 로고
    • Nuclear shift of hnRNP K protein in neoplasms and other states of enhanced cell proliferation
    • DOI 10.1038/sj.bjc.6601250
    • Ostrowski J and Bomsztyk K: Nuclear shift of hnRNP K protein in neoplasms and other states of enhanced cell proliferation. Br J Cancer 89: 1493-1501, 2003. (Pubitemid 37386605)
    • (2003) British Journal of Cancer , vol.89 , Issue.8 , pp. 1493-1501
    • Ostrowski, J.1    Bomsztyk, K.2
  • 12
    • 33749370720 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer
    • DOI 10.1038/sj.bjc.6603349, PII 6603349
    • Carpenter B, McKay M, Dundas SR, Lawrie LC, Telfer C and Murray GI: Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localized and is associated with poor prognosis in colorectal cancer. Br J Cancer 95: 921-927, 2006. (Pubitemid 44498109)
    • (2006) British Journal of Cancer , vol.95 , Issue.7 , pp. 921-927
    • Carpenter, B.1    Mckay, M.2    Dundas, S.R.3    Lawrie, L.C.4    Telfer, C.5    Murray, G.I.6
  • 13
    • 52449111395 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein K and thymidine phosphorylase are independent prognostic and therapeutic markers for nasopharyngeal carcinoma
    • Chen LC, Hsueh C, Tsang NM, Liang Y, Chang KP, Hao SP, Yu JS and Chang YS: Heterogeneous nuclear ribonucleoprotein K and thymidine phosphorylase are independent prognostic and therapeutic markers for nasopharyngeal carcinoma. Clin Cancer Res 14: 3807-3813, 2008.
    • (2008) Clin Cancer Res , vol.14 , pp. 3807-3813
    • Chen, L.C.1    Hsueh, C.2    Tsang, N.M.3    Liang, Y.4    Chang, K.P.5    Hao, S.P.6    Yu, J.S.7    Chang, Y.S.8
  • 15
    • 77955711835 scopus 로고    scopus 로고
    • The antiapoptotic protein FLIP, is regulated by heterogeneous nuclear ribonucleoprotein K and correlates with poor overall survival of nasopharyngeal carcinoma patients
    • Chen LC, Chung IC, Hsueh C, Tsang NM, Chi LM, Liang Y, Chen CC, Wang LJ and Chang YS: The antiapoptotic protein FLIP, is regulated by heterogeneous nuclear ribonucleoprotein K and correlates with poor overall survival of nasopharyngeal carcinoma patients. Cell Death Differ 17: 1463-1473, 2010.
    • (2010) Cell Death Differ , vol.17 , pp. 1463-1473
    • Chen, L.C.1    Chung, I.C.2    Hsueh, C.3    Tsang, N.M.4    Chi, L.M.5    Liang, Y.6    Chen, C.C.7    Wang, L.J.8    Chang, Y.S.9
  • 17
    • 79951579335 scopus 로고    scopus 로고
    • The expression profile of RNA-binding proteins in primary and metastatic colorectal cancer: Relationship of heterogeneous nuclear ribonucleoproteins with prognosis
    • Hope NR and Murray GI: The expression profile of RNA-binding proteins in primary and metastatic colorectal cancer: relationship of heterogeneous nuclear ribonucleoproteins with prognosis. Human Pathol 42: 392-402, 2011.
    • (2011) Human Pathol , vol.42 , pp. 392-402
    • Hope, N.R.1    Murray, G.I.2
  • 18
    • 84872799855 scopus 로고    scopus 로고
    • Immunohistochemical detection of HSP27 and hnRNP K as prognostic and predictive biomarkers for colorectal cancer
    • Wang F, Zhang P, Shi C, Yang Y and Qin H: Immunohistochemical detection of HSP27 and hnRNP K as prognostic and predictive biomarkers for colorectal cancer. Med Oncol 29: 1780- 1788, 2012.
    • (2012) Med Oncol , vol.29 , pp. 1780-1788
    • Wang, F.1    Zhang, P.2    Shi, C.3    Yang, Y.4    Qin, H.5
  • 19
    • 1642291861 scopus 로고    scopus 로고
    • Differential protein synthesis and expression levels in normal and neoplastic human prostate cells and their regulation by type I and II interferons
    • DOI 10.1038/sj.onc.1207297
    • Nagano K, Masters JR, Akpan A, Yang A, Corless S, Wood C, Hastie C, Zvelebil M, Cramer R and Naaby-Hansen S: Differential protein synthesis and expression levels in normal and neoplastic human prostate cells and their regulation by type I and II interferons. Oncogene 23: 1693-1703, 2004. (Pubitemid 38445161)
    • (2004) Oncogene , vol.23 , Issue.9 , pp. 1693-1703
    • Nagano, K.1    Masters, J.R.2    Akpan, A.3    Yang, A.4    Corless, S.5    Wood, C.6    Hastie, C.7    Zvelebil, M.8    Cramer, R.9    Naaby-Hansen, S.10
  • 21
    • 0038475967 scopus 로고    scopus 로고
    • Nuclear matrix proteins changes in cancerous prostatetissues and their prognostic value in clinically localized prostate cancer
    • DOI 10.1002/pros.10248
    • Boccardo F, Rubagotti A, Carmignani G, Romagnoli A, Nicolò G, Barboro P, Parodi S, Patrone E and Balbi C: Nuclear matrix proteins changes in cancerous prostate tissues and their prognostic value in clinically localized prostate cancer. Prostate 55: 259-264, 2003. (Pubitemid 36618184)
    • (2003) Prostate , vol.55 , Issue.4 , pp. 259-264
    • Boccardo, F.1    Rubagotti, A.2    Carmignani, G.3    Romagnoli, A.4    Nicolo, G.5    Barboro, P.6    Parodi, S.7    Patrone, E.8    Balbi, C.9
  • 23
    • 79959289248 scopus 로고    scopus 로고
    • Androgen receptor and heterogeneous nuclear ribonucleoprotein K colocalize in the nucleoplasm and are modulated by bicalutamide and 4-hydroxy-tamoxifen in prostatic cancer cell lines
    • Barboro P, Repaci E, Ferrari N, Rubagotti A, Boccardo F and Balbi C: Androgen receptor and heterogeneous nuclear ribonucleoprotein K colocalize in the nucleoplasm and are modulated by bicalutamide and 4-hydroxy-tamoxifen in prostatic cancer cell lines. Prostate 71: 1466-1479, 2011.
    • (2011) Prostate , vol.71 , pp. 1466-1479
    • Barboro, P.1    Repaci, E.2    Ferrari, N.3    Rubagotti, A.4    Boccardo, F.5    Balbi, C.6
  • 24
    • 0036187849 scopus 로고    scopus 로고
    • Establishment and characterization of androgen-independent human prostate cancer LNCaP cell model
    • DOI 10.1002/pros.10054
    • Igawa T, Lin FF, Lee MS, Karan D, Batra SK and Lin MF: Establishment and characterization of androgen-independent human prostate cancer LNCaP cell model. Prostate 50: 222-235, 2002. (Pubitemid 34184661)
    • (2002) Prostate , vol.50 , Issue.4 , pp. 222-235
    • Igawa, T.1    Lin, F.-F.2    Lee, M.-S.3    Karan, D.4    Batra, S.K.5    Lin, M.-F.6
  • 25
    • 0037112372 scopus 로고    scopus 로고
    • Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line
    • Tepper CG, Boucher DL, Ryan PE, Ma AH, Xia L, Lee LF, Pretlow TG and Kung HJ: Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Res 62: 6606-6614, 2002. (Pubitemid 35364127)
    • (2002) Cancer Research , vol.62 , Issue.22 , pp. 6606-6614
    • Tepper, C.G.1    Boucher, D.L.2    Ryan, P.E.3    Ma, A.-H.4    Xia, L.5    Lee, L.-F.6    Pretlow, T.G.7    Kung, H.-J.8
  • 27
    • 0032940563 scopus 로고    scopus 로고
    • Immunohistochemical quantitation of androgen receptor expression using color video image analysis
    • DOI 10.1002/(SICI)1097-0320(19990101)35:1<2::AID-C
    • Kim D, Gregory CW, Smith GJ and Mohler JL: Immunohistochemical quantitation of androgen receptor expression using color video image analysis. Cytometry 35: 2-10, 1999. (Pubitemid 29031186)
    • (1999) Cytometry , vol.35 , Issue.1 , pp. 2-10
    • Kim, D.1    Gregory, C.W.2    Smith, G.J.3    Mohler, J.L.4
  • 29
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL and Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53: 457-481, 1958.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 30
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox DR: Regression models and life tables. JR Stat Soc B 34: 187-220, 1972.
    • (1972) JR Stat Soc B , vol.34 , pp. 187-220
    • Cox, D.R.1
  • 32
    • 2342558431 scopus 로고    scopus 로고
    • Androgen receptor in prostate cancer
    • DOI 10.1210/er.2002-0032
    • Heinlein CA and Chang C: Androgen receptor in prostate cancer. Endocr Rev 25: 276-308, 2004. (Pubitemid 38501396)
    • (2004) Endocrine Reviews , vol.25 , Issue.2 , pp. 276-308
    • Heinlein, C.A.1    Chang, C.2
  • 33
    • 42949165515 scopus 로고    scopus 로고
    • A role for the androgen-receptor in clinically localized and advanced prostate cancer
    • Mohler JM: A role for the androgen-receptor in clinically localized and advanced prostate cancer. Best Pract Res Clin Endocrinol Metab 22: 357-372, 2008.
    • (2008) Best Pract Res Clin Endocrinol Metab , vol.22 , pp. 357-372
    • Mohler, J.M.1
  • 35
    • 84879604025 scopus 로고    scopus 로고
    • AKT upregulates B-Raf Ser445 phosphorylation and ERK1/2 activation in prostate cancer cells in response to androgen depletion
    • Hong SK, Jeong JH, Chan AM and Park JI: AKT upregulates B-Raf Ser445 phosphorylation and ERK1/2 activation in prostate cancer cells in response to androgen depletion. Exp Cell Res 319: 1732-1743, 2013.
    • (2013) Exp Cell Res , vol.319 , pp. 1732-1743
    • Hong, S.K.1    Jeong, J.H.2    Chan, A.M.3    Park, J.I.4
  • 36
    • 75449105857 scopus 로고    scopus 로고
    • Blood and tissue biomarkers in prostate cancer: State of the art
    • Fiorentino M, Capizzi E and Loda M: Blood and tissue biomarkers in prostate cancer: State of the art. Urol Clin North Am 37: 131-141, 2010.
    • (2010) Urol Clin North Am , vol.37 , pp. 131-141
    • Fiorentino, M.1    Capizzi, E.2    Loda, M.3
  • 37
    • 0027536495 scopus 로고
    • Image analysis of androgen receptor immunostaining in metastatic prostate cancer: Heterogeneity as a predictor of response to hormonal therapy
    • Sadi M and Barrack ER: Image analysis of androgen receptor immunostaining in metastatic prostate cancer. Heterogeneity as a predictor of response to hormonal therapy. Cancer 71: 2574-2580, 1993. (Pubitemid 23100494)
    • (1993) Cancer , vol.71 , Issue.8 , pp. 2574-2580
    • Sadi, M.V.1    Barrack, E.R.2
  • 40
    • 61349097316 scopus 로고    scopus 로고
    • Loss of androgen receptor in aging and oxidative stress through Myb protooncoprotein-regulated reciprocal chromatin dynamics of p53 and poly(ADP-ribose) polymerase PARP-1
    • Shi L, Ko S, Kim S, Echchgadda I, Oh TS, Song CS and Chatterjee B: Loss of androgen receptor in aging and oxidative stress through Myb protooncoprotein-regulated reciprocal chromatin dynamics of p53 and poly(ADP-ribose) polymerase PARP-1. J Biol Chem 283: 36474-36485, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 36474-36485
    • Shi, L.1    Ko, S.2    Kim, S.3    Echchgadda, I.4    Oh, T.S.5    Song, C.S.6    Chatterjee, B.7
  • 42
    • 65649100065 scopus 로고    scopus 로고
    • Novel antivascular efficacy of metronomic docetaxel therapy in prostate cancer: HnRNP K as a player
    • Benelli R, Monteghirfo S, Balbi C, Barboro P and Ferrari N: Novel antivascular efficacy of metronomic docetaxel therapy in prostate cancer: hnRNP K as a player. Int J Cancer 124: 2989-2996, 2009.
    • (2009) Int J Cancer , vol.124 , pp. 2989-2996
    • Benelli, R.1    Monteghirfo, S.2    Balbi, C.3    Barboro, P.4    Ferrari, N.5
  • 43
    • 80053653689 scopus 로고    scopus 로고
    • Dynamic rewiring of the androgen receptor protein interaction network correlates with prostate cancer clinical outcomes
    • Paliouras M, Zaman N, Lumbroso R, Kapogeorgakis L, Beitel LK, Wang E and Trifiro M: Dynamic rewiring of the androgen receptor protein interaction network correlates with prostate cancer clinical outcomes. Integr Biol 3: 1020-1032, 2011.
    • (2011) Integr Biol , vol.3 , pp. 1020-1032
    • Paliouras, M.1    Zaman, N.2    Lumbroso, R.3    Kapogeorgakis, L.4    Beitel, L.K.5    Wang, E.6    Trifiro, M.7
  • 44
    • 33846603663 scopus 로고    scopus 로고
    • Androgen receptor coregulators and their involvement in the development and progression of prostate cancer
    • DOI 10.1002/ijc.22365
    • Chmelar R, Buchanan G, Need EF, Tilley W and Greenberg NM: Androgen receptor coregulators and their involvement in the development and progression of prostate cancer. Int J Cancer 120: 719-733, 2007. (Pubitemid 46175390)
    • (2007) International Journal of Cancer , vol.120 , Issue.4 , pp. 719-733
    • Chmelar, R.1    Buchanan, G.2    Need, E.F.3    Tilley, W.4    Greenberg, N.M.5
  • 45
    • 84893365879 scopus 로고    scopus 로고
    • Androgen Receptor activity is affected by both nuclear matrix localization and the phosphorylation status of the heterogeneous nuclear ribonucleoprotein K in anti-androgen-treated LNCaP cells
    • Barboro P, Borzì L, Repaci E, Ferrari N and Balbi C: Androgen Receptor activity is affected by both nuclear matrix localization and the phosphorylation status of the heterogeneous nuclear ribonucleoprotein K in anti-androgen-treated LNCaP cells. PLoS One 8: e79212, 2013.
    • (2013) PLoS One , vol.8
    • Barboro, P.1    Borzì, L.2    Repaci, E.3    Ferrari, N.4    Balbi, C.5
  • 47
    • 84861576558 scopus 로고    scopus 로고
    • Regulation of neuroendocrine differentiation by AKT/hnRNPK/AR/β- catenin signaling in prostate cancer cells
    • Ciarlo M, Benelli R, Barbieri O, Minghelli S, Barboro P, Balbi C and Ferrari N: Regulation of neuroendocrine differentiation by AKT/hnRNPK/AR/β- catenin signaling in prostate cancer cells. Int J Cancer 131: 582-590, 2012.
    • (2012) Int J Cancer , vol.131 , pp. 582-590
    • Ciarlo, M.1    Benelli, R.2    Barbieri, O.3    Minghelli, S.4    Barboro, P.5    Balbi, C.6    Ferrari, N.7
  • 48
    • 84878221242 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein K (hnRNP-K) promotes tumor metastasis by induction of genes involved in extracellular matrix, cell movement, and angiogenesis
    • Gao R, Yu Y, Inoue A, Widodo N, Kaul SC and Wadhwa R: Heterogeneous nuclear ribonucleoprotein K (hnRNP-K) promotes tumor metastasis by induction of genes involved in extracellular matrix, cell movement, and angiogenesis. J Biol Chem 288: 15046-15056, 2013.
    • (2013) J Biol Chem , vol.288 , pp. 15046-15056
    • Gao, R.1    Yu, Y.2    Inoue, A.3    Widodo, N.4    Kaul, S.C.5    Wadhwa, R.6


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