메뉴 건너뛰기




Volumn 31, Issue 9, 2014, Pages 834-845

Testosterone dose dependently prevents bone and muscle loss in rodents after spinal cord injury

Author keywords

androgen; microCT; osteoporosis; sex steroids; skeletal

Indexed keywords

ANDROGEN; CARBOXY TERMINAL TELOPEPTIDE; ESTRADIOL; OSTEOCALCIN; TESTOSTERONE; TESTOSTERONE ENANTATE;

EID: 84899087801     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2013.3155     Document Type: Article
Times cited : (50)

References (50)
  • 1
    • 84860723581 scopus 로고    scopus 로고
    • Epidemiology of traumatic spinal cord injury: Trends and future implications
    • Devivo, M.J. (2012). Epidemiology of traumatic spinal cord injury: trends and future implications. Spinal Cord 50, 365-372.
    • (2012) Spinal Cord , vol.50 , pp. 365-372
    • Devivo, M.J.1
  • 2
    • 33847023990 scopus 로고    scopus 로고
    • Bone loss and muscle atrophy in spinal cord injury: Epidemiology, fracture prediction, and rehabilitation strategies
    • Giangregorio, L., and McCartney, N. (2006). Bone loss and muscle atrophy in spinal cord injury: epidemiology, fracture prediction, and rehabilitation strategies. J. Spinal Cord Med. 29, 489-500.
    • (2006) J. Spinal Cord Med. , vol.29 , pp. 489-500
    • Giangregorio, L.1    McCartney, N.2
  • 3
    • 12144286719 scopus 로고    scopus 로고
    • Long-term changes in bone metabolism, bone mineral density, quantitative ultrasound parameters, and fracture incidence after spinal cord injury: A crosssectional observational study in 100 paraplegic men
    • Zehnder, Y., Luthi, M., Michel, D., Knecht, H., Perrelet, R., Neto, I., Kraenzlin, M., Zach, G., and Lippuner, K. (2004). Long-term changes in bone metabolism, bone mineral density, quantitative ultrasound parameters, and fracture incidence after spinal cord injury: a crosssectional observational study in 100 paraplegic men. Osteoporos. Int. 15, 180-189.
    • (2004) Osteoporos. Int. , vol.15 , pp. 180-189
    • Zehnder, Y.1    Luthi, M.2    Michel, D.3    Knecht, H.4    Perrelet, R.5    Neto, I.6    Kraenzlin, M.7    Zach, G.8    Lippuner, K.9
  • 4
    • 2342482496 scopus 로고    scopus 로고
    • Relationship between the duration of paralysis and bone structure: A pQCT study of spinal cord injured individuals
    • Eser, P., Frotzler, A., Zehnder, Y., Wick, L., Knecht, H., Denoth, J., and Schiessl, H. (2004). Relationship between the duration of paralysis and bone structure: a pQCT study of spinal cord injured individuals. Bone 34, 869-880.
    • (2004) Bone , vol.34 , pp. 869-880
    • Eser, P.1    Frotzler, A.2    Zehnder, Y.3    Wick, L.4    Knecht, H.5    Denoth, J.6    Schiessl, H.7
  • 5
    • 0030624138 scopus 로고    scopus 로고
    • Fractures after myelopathy: The risk quantified
    • Frisbie, J.H. (1997). Fractures after myelopathy: the risk quantified. J. Spinal Cord Med. 20, 66-69.
    • (1997) J. Spinal Cord Med. , vol.20 , pp. 66-69
    • Frisbie, J.H.1
  • 6
    • 0032863335 scopus 로고    scopus 로고
    • Influence of complete spinal cord injury on skeletal muscle cross-sectional area within the first 6 months of injury
    • Castro, M.J., Apple, D.F., Jr., Hillegass, E.A., and Dudley, G.A. (1999). Influence of complete spinal cord injury on skeletal muscle cross-sectional area within the first 6 months of injury. Eur. J. Appl. Physiol. Occup. Physiol. 80, 373-378.
    • (1999) Eur. J. Appl. Physiol. Occup. Physiol. , vol.80 , pp. 373-378
    • Castro, M.J.1    Apple Jr., D.F.2    Hillegass, E.A.3    Dudley, G.A.4
  • 7
    • 0034089025 scopus 로고    scopus 로고
    • Soft tissue body composition differences in monozygotic twins discordant for spinal cord injury
    • Spungen, A.M., Wang, J., Pierson, R.N., Jr., and Bauman, W.A. (2000). Soft tissue body composition differences in monozygotic twins discordant for spinal cord injury. J. Appl. Physiol. 88, 1310-1315.
    • (2000) J. Appl. Physiol. , vol.88 , pp. 1310-1315
    • Spungen, A.M.1    Wang, J.2    Pierson Jr., R.N.3    Bauman, W.A.4
  • 8
    • 0037252148 scopus 로고    scopus 로고
    • Effects of testosterone replacement therapy on skeletal muscle after spinal cord injury
    • Gregory, C.M., Vandenborne, K., Huang, H.F., Ottenweller, J.E., and Dudley, G.A. (2003). Effects of testosterone replacement therapy on skeletal muscle after spinal cord injury. Spinal Cord 41, 23-28.
    • (2003) Spinal Cord , vol.41 , pp. 23-28
    • Gregory, C.M.1    Vandenborne, K.2    Huang, H.F.3    Ottenweller, J.E.4    Dudley, G.A.5
  • 9
    • 84861994962 scopus 로고    scopus 로고
    • Nandrolone normalizes determinants of muscle mass and fiber type after spinal cord injury
    • Wu, Y., Zhao, J., Zhao, W., Pan, J., Bauman, W.A., and Cardozo, C.P. (2012). Nandrolone normalizes determinants of muscle mass and fiber type after spinal cord injury. J. Neurotrauma 29, 1663-1675.
    • (2012) J. Neurotrauma , vol.29 , pp. 1663-1675
    • Wu, Y.1    Zhao, J.2    Zhao, W.3    Pan, J.4    Bauman, W.A.5    Cardozo, C.P.6
  • 10
    • 84862130602 scopus 로고    scopus 로고
    • Neuroprotective effects of testosterone on motoneuron and muscle morphology following spinal cord injury
    • Byers, J.S., Huguenard, A.L., Kuruppu, D., Liu, N.K., Xu, X.M., and Sengelaub, D.R. (2012). Neuroprotective effects of testosterone on motoneuron and muscle morphology following spinal cord injury. J. Comp. Neurol. 520, 2683-2696.
    • (2012) J. Comp. Neurol , vol.520 , pp. 2683-2696
    • Byers, J.S.1    Huguenard, A.L.2    Kuruppu, D.3    Liu, N.K.4    Xu, X.M.5    Sengelaub, D.R.6
  • 11
    • 79960700198 scopus 로고    scopus 로고
    • A smallscale clinical trial to determine the safety and efficacy of testosterone replacement therapy in hypogonadal men with spinal cord injury
    • Bauman, W.A., Cirnigliaro, C.M., La Fountaine, M.F., Jensen, A.M., Wecht, J.M., Kirshblum, S.C., and Spungen, A.M. (2011). A smallscale clinical trial to determine the safety and efficacy of testosterone replacement therapy in hypogonadal men with spinal cord injury. Horm. Metab. Res. 43, 574-579.
    • (2011) Horm. Metab. Res. , vol.43 , pp. 574-579
    • Bauman, W.A.1    Cirnigliaro, C.M.2    La Fountaine, M.F.3    Jensen, A.M.4    Wecht, J.M.5    Kirshblum, S.C.6    Spungen, A.M.7
  • 17
    • 34247632616 scopus 로고    scopus 로고
    • Differences of bone mass and bone structure in osteopenic rat models caused by spinal cord injury and ovariectomy
    • Jiang, S.D., Shen, C., Jiang, L.S., and Dai, L.Y. (2007). Differences of bone mass and bone structure in osteopenic rat models caused by spinal cord injury and ovariectomy. Osteoporos. Int. 18, 743-750.
    • (2007) Osteoporos. Int. , vol.18 , pp. 743-750
    • Jiang, S.D.1    Shen, C.2    Jiang, L.S.3    Dai, L.Y.4
  • 18
    • 44949214642 scopus 로고    scopus 로고
    • Effects of spinal cord injury and hindlimb immobilization on sublesional and supralesional bones in young growing rats
    • Liu, D., Zhao, C.Q., Li, H., Jiang, S.D., Jiang, L.S., and Dai, L.Y. (2008). Effects of spinal cord injury and hindlimb immobilization on sublesional and supralesional bones in young growing rats. Bone 43, 119-125.
    • (2008) Bone , vol.43 , pp. 119-125
    • Liu, D.1    Zhao, C.Q.2    Li, H.3    Jiang, S.D.4    Jiang, L.S.5    Dai, L.Y.6
  • 19
    • 33748642989 scopus 로고    scopus 로고
    • Spinal cord injury causes more damage to bone mass, bone structure, biomechanical properties and bone metabolism than sciatic neurectomy in young rats
    • Jiang, S.D., Jiang, L.S., and Dai, L.Y. (2006). Spinal cord injury causes more damage to bone mass, bone structure, biomechanical properties and bone metabolism than sciatic neurectomy in young rats. Osteoporos. Int. 17, 1552-1561.
    • (2006) Osteoporos. Int. , vol.17 , pp. 1552-1561
    • Jiang, S.D.1    Jiang, L.S.2    Dai, L.Y.3
  • 20
    • 33947190613 scopus 로고    scopus 로고
    • Changes in bone mass, bone structure, bone biomechanical properties, and bone metabolism after spinal cord injury: A 6-month longitudinal study in growing rats
    • Jiang, S.D., Jiang, L.S., and Dai, L.Y. (2007). Changes in bone mass, bone structure, bone biomechanical properties, and bone metabolism after spinal cord injury: a 6-month longitudinal study in growing rats. Calcif. Tissue Int. 80, 167-175.
    • (2007) Calcif. Tissue Int. , vol.80 , pp. 167-175
    • Jiang, S.D.1    Jiang, L.S.2    Dai, L.Y.3
  • 24
    • 0030157694 scopus 로고    scopus 로고
    • Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
    • Basso, D.M., Beattie, M.S., and Bresnahan, J.C. (1996). Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp. Neurol. 139, 244-256.
    • (1996) Exp. Neurol. , vol.139 , pp. 244-256
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 25
    • 46749124693 scopus 로고    scopus 로고
    • A longitudinal study of skeletal muscle following spinal cord injury and locomotor training
    • Liu, M., Bose, P., Walter, G.A., Thompson, F.J., and Vandenborne, K. (2008). A longitudinal study of skeletal muscle following spinal cord injury and locomotor training. Spinal Cord 46, 488-493.
    • (2008) Spinal Cord , vol.46 , pp. 488-493
    • Liu, M.1    Bose, P.2    Walter, G.A.3    Thompson, F.J.4    Vandenborne, K.5
  • 26
    • 77950518572 scopus 로고    scopus 로고
    • Tissue selectivity and potential clinical applications of trenbolone (17beta-hydroxyestra-4, 9,11-trien-3-one): A potent anabolic steroid with reduced androgenic and estrogenic activity
    • Yarrow, J.F., McCoy, S.C., and Borst, S.E. (2010). Tissue selectivity and potential clinical applications of trenbolone (17beta-hydroxyestra-4,9,11- trien-3-one): A potent anabolic steroid with reduced androgenic and estrogenic activity. Steroids 75, 377-389.
    • (2010) Steroids , vol.75 , pp. 377-389
    • Yarrow, J.F.1    McCoy, S.C.2    Borst, S.E.3
  • 27
    • 45349086665 scopus 로고    scopus 로고
    • Effects of castration and testosterone replacement on the antioxidant defense system in rat left ventricle
    • Klapcinska, B., Jagsz, S., Sadowska-Krepa, E., Gorski, J., Kempa, K., and Langfort, J. (2008). Effects of castration and testosterone replacement on the antioxidant defense system in rat left ventricle. J. Physiol. Sci. 58, 173-177.
    • (2008) J. Physiol. Sci. , vol.58 , pp. 173-177
    • Klapcinska, B.1    Jagsz, S.2    Sadowska-Krepa, E.3    Gorski, J.4    Kempa, K.5    Langfort, J.6
  • 28
    • 0024407244 scopus 로고
    • Testosterone dose-dependency of sexual and nonsexual behaviors in the gonadotropin-releasing hormone antagonisttreated male rat
    • Fielder, T.J., Peacock, N.R., McGivern, R.F., Swerdloff, R.S., and Bhasin, S. (1989). Testosterone dose-dependency of sexual and nonsexual behaviors in the gonadotropin-releasing hormone antagonisttreated male rat. J. Androl. 10, 167-173.
    • (1989) J. Androl. , vol.10 , pp. 167-173
    • Fielder, T.J.1    Peacock, N.R.2    McGivern, R.F.3    Swerdloff, R.S.4    Bhasin, S.5
  • 34
    • 84877715751 scopus 로고    scopus 로고
    • The central nervous system (CNS)-independent anti-bone-resorptive activity of muscle contraction and the underlying molecular and cellular signatures
    • Qin, W., Sun, L., Cao, J., Peng, Y., Collier, L., Wu, Y., Creasey, G., Li, J., Qin, Y., Jarvis, J., Bauman, W.A., Zaidi, M., and Cardozo, C. (2013). The central nervous system (CNS)-independent anti-bone-resorptive activity of muscle contraction and the underlying molecular and cellular signatures. J. Biol. Chem. 288, 13511-13521.
    • (2013) J. Biol. Chem. , vol.288 , pp. 13511-13521
    • Qin, W.1    Sun, L.2    Cao, J.3    Peng, Y.4    Collier, L.5    Wu, Y.6    Creasey, G.7    Li, J.8    Qin, Y.9    Jarvis, J.10    Bauman, W.A.11    Zaidi, M.12    Cardozo, C.13
  • 35
    • 43149105785 scopus 로고    scopus 로고
    • Spinal cord injury causes rapid osteoclastic resorption and growth plate abnormalities in growing rats (SCI-induced bone loss in growing rats
    • Morse, L., Teng, Y.D., Pham, L., Newton, K., Yu, D., Liao, W.L., Kohler, T., Muller, R., Graves, D., Stashenko, P., and Battaglino, R. (2008). Spinal cord injury causes rapid osteoclastic resorption and growth plate abnormalities in growing rats (SCI-induced bone loss in growing rats). Osteoporos. Int. 19, 645-652.
    • (2008) Osteoporos. Int. , vol.19 , pp. 645-652
    • Morse, L.1    Teng, Y.D.2    Pham, L.3    Newton, K.4    Yu, D.5    Liao, W.L.6    Kohler, T.7    Muller, R.8    Graves, D.9    Stashenko, P.10    Battaglino, R.11
  • 36
    • 0033910897 scopus 로고    scopus 로고
    • Supralesional and sublesional bone mineral density in spinal cord-injured patients
    • Dauty, M., Perrouin Verbe, B., Maugars, Y., Dubois, C., and Mathe, J.F. (2000). Supralesional and sublesional bone mineral density in spinal cord-injured patients. Bone 27, 305-309.
    • (2000) Bone , vol.27 , pp. 305-309
    • Dauty, M.1    Perrouin Verbe, B.2    Maugars, Y.3    Dubois, C.4    Mathe, J.F.5
  • 37
    • 18044375988 scopus 로고    scopus 로고
    • Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone
    • Mittra, E., Rubin, C., and Qin, Y.X. (2005). Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone. J. Biomech. 38, 1229-1237.
    • (2005) J. Biomech. , vol.38 , pp. 1229-1237
    • Mittra, E.1    Rubin, C.2    Qin, Y.X.3
  • 39
    • 0035137810 scopus 로고    scopus 로고
    • Sex steroids and bone
    • Compston, J.E. (2001). Sex steroids and bone. Physiol. Rev. 81, 419-447.
    • (2001) Physiol. Rev. , vol.81 , pp. 419-447
    • Compston, J.E.1
  • 41
  • 43
    • 0025457129 scopus 로고
    • Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats
    • Turner, R.T., Wakley, G.K., and Hannon, K.S. (1990). Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats. J. Orthop. Res. 8, 612-617.
    • (1990) J. Orthop. Res. , vol.8 , pp. 612-617
    • Turner, R.T.1    Wakley, G.K.2    Hannon, K.S.3
  • 46
    • 84859927249 scopus 로고    scopus 로고
    • Intracrine and myotrophic roles of 5alpha-reductase and androgens: A review
    • Yarrow, J.F., McCoy, S.C., and Borst, S.E. (2012). Intracrine and myotrophic roles of 5alpha-reductase and androgens: a review. Med. Sci. Sports Exerc. 44, 818-826.
    • (2012) Med. Sci. Sports Exerc. , vol.44 , pp. 818-826
    • Yarrow, J.F.1    McCoy, S.C.2    Borst, S.E.3
  • 47
    • 67549132823 scopus 로고    scopus 로고
    • Improved functional recovery with oxandrolone after spinal cord injury in rats
    • Zeman, R.J., Bauman, W.A., Wen, X., Ouyang, N., Etlinger, J.D., and Cardozo, C.P. (2009). Improved functional recovery with oxandrolone after spinal cord injury in rats. Neuroreport 20, 864-868.
    • (2009) Neuroreport , vol.20 , pp. 864-868
    • Zeman, R.J.1    Bauman, W.A.2    Wen, X.3    Ouyang, N.4    Etlinger, J.D.5    Cardozo, C.P.6
  • 49
    • 84880788748 scopus 로고    scopus 로고
    • Prostate volume in male patients with spinal cord injury: A question of nerves?
    • Pannek, J., Bartel, P., Gocking, K., and Frotzler, A. (2013). Prostate volume in male patients with spinal cord injury: a question of nerves? BJU Int. 112, 495-500.
    • (2013) BJU Int. , vol.112 , pp. 495-500
    • Pannek, J.1    Bartel, P.2    Gocking, K.3    Frotzler, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.