Design, synthesis and pharmacological evaluation of novel polycyclic heteroarene ethers as PDE10A inhibitors: Part i

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 9, 2014, Pages 2073-2078

  Das, Sanjib ^a   Harde, Rajendra L ^a   Shelke, Dnyaneshwar E ^a   Khairatkar Joshi, Neelima ^a   Bajpai, Malini ^a   Sapalya, Ratika S ^a   Surve, Harshada V ^a   Gudi, Girish S ^a   Pattem, Rambabu ^a   Behera, Dayanidhi B ^a   Jadhav, Satyawan B ^a   Thomas, Abraham ^a  

^a Glenmark Pharmaceuticals Limited   (India)

Author keywords

Met ID studies; PDE10A inhibitors; Pyrido 2 3 b indoles; Pyrrolo 3 2 b quinolines

Indexed keywords

INDOLE DERIVATIVE; PDE10A PROTEIN, HUMAN; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; QUINOLINE DERIVATIVE;

ANIMAL; CHEMISTRY; DRUG DESIGN; HUMAN; LIVER MICROSOME; METABOLISM; RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; DRUG DESIGN; HUMANS; INDOLES; MICROSOMES, LIVER; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; QUINOLINES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84899087146     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.03.054     Document Type: Article

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