Treatment with the immunomodulator FTY720 (Fingolimod) significantly reduces renal inflammation in murine unilateral ureteral obstruction

Journal of Urology

Volumn 191, Issue 5 SUPPL, 2014, Pages 1508-1516

  Thangada, Shobha ^a,b   Shapiro, Linda H ^a,b   Silva, Cynthia ^b   Yamase, Harold ^a   Hla, Timothy ^c   Ferrer, Fernando A ^a,b  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b Farmington   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

fibrosis; fingolimod; inflammation; kidney; ureteral obstruction

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CXCL1 CHEMOKINE; FINGOLIMOD; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY EPITHELIUM; KIDNEY FIBROSIS; KIDNEY PARENCHYMA; MACROPHAGE; MOUSE; MYOFIBROBLAST; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHAM PROCEDURE; TREATMENT RESPONSE; UNILATERAL URETERAL OBSTRUCTION; URETER OBSTRUCTION; WESTERN BLOTTING;

FIBROSIS; FINGOLIMOD; INFLAMMATION; KIDNEY; URETERAL OBSTRUCTION;

ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; FEMALE; FIBROSIS; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATION; KIDNEY; MALE; MICE; MICE, INBRED C57BL; PROPYLENE GLYCOLS; SPHINGOSINE; TRANSFORMING GROWTH FACTOR BETA1; URETERAL OBSTRUCTION;

EID: 84899085652     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2013.10.072     Document Type: Article

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