Criteria for clinically relevant weakness and low lean mass and their longitudinal association with incident mobility impairment and mortality: The Foundation for the National Institutes of Health (FNIH) sarcopenia project

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 69 A, Issue 5, 2014, Pages 576-583

  McLean, Robert R ^a,b   Shardell, Michelle D ^c   Alley, Dawn E ^c   Cawthon, Peggy M ^d   Fragala, Maren S ^e,f   Harris, Tamara B ^g   Kenny, Anne M ^e   Peters, Katherine W ^d   Ferrucci, Luigi ^g   Guralnik, Jack M ^c   Kritchevsky, Stephen B ^h   Kiel, Douglas P ^a,b   Vassileva, Maria T ⁱ   Xue, Qian Li ^j   Perera, Subashan ^k   Studenski, Stephanie A ^k,l   Dam, Thuy Tien L ^m  

^a Hebrew SeniorLife Institute for Aging Research   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^e UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^f UNIVERSITY OF CENTRAL FLORIDA   (United States)

^g NATIONAL INSTITUTE ON AGING   (United States)

^h WAKE FOREST SCHOOL OF MEDICINE   (United States)

ⁱ NATIONAL INSTITUTES OF HEALTH   (United States)

^j JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^l VETERANS AFFAIRS MEDICAL CENTER   (United States)

^m New York Presbyterian Columbia University Medical Center   (United States)

more..

Author keywords

Impairment.; Mobility; Muscle; Sarcopenia

Indexed keywords

AGED; ARTICLE; BODY WEIGHT; FEMALE; GAIT; HAND STRENGTH; HUMAN; IMPAIRMENT.; INCIDENCE; LONGITUDINAL STUDY; MALE; MOBILITY; MORTALITY; MUSCLE; MUSCLE WEAKNESS; NATIONAL HEALTH ORGANIZATION; PATHOPHYSIOLOGY; PHYSIOLOGY; SARCOPENIA; UNITED STATES; WALKING DIFFICULTY;

IMPAIRMENT.; MOBILITY; MUSCLE; SARCOPENIA;

AGED; FEMALE; GAIT; HAND STRENGTH; HUMANS; INCIDENCE; LONGITUDINAL STUDIES; MALE; MOBILITY LIMITATION; MUSCLE WEAKNESS; NATIONAL INSTITUTES OF HEALTH (U.S.); SARCOPENIA; THINNESS; UNITED STATES;

EID: 84899073317     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glu012     Document Type: Article

References (33)

1. Rosenberg IH. Sarcopenia: Origins and clinical relevance. J Nutr. 1997;127:990S-991S.
2. Baumgartner RN, Koehler KM, Gallagher D, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998;147:755-763
3. Melton LJ 3rd, Khosla S, Crowson CS, O'Connor MK, O'Fallon WM, Riggs BL. Epidemiology of sarcopenia. J Am Geriatr Soc. 2000;48:625-630
4. Lauretani F, Russo CR, Bandinelli S, et al. Age-Associated changes in skeletal muscles and their effect on mobility: An operational diagnosis of sarcopenia. J Appl Physiol. 2003;95:1851-1860
5. Visser M, Goodpaster BH, Kritchevsky SB, et al. Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons. J Gerontol A Biol Sci Med Sci. 2005;60:324-333
6. Fielding RA, Vellas B, Evans WJ, et al. Sarcopenia: An undiagnosed condition in older adults. Current consensus definition: Prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011;12:249-256. doi:10.1016/j. jamda.2011.01.003
7. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412-423. doi:10.1093/ageing/ afq034
8. Muscaritoli M, Anker SD, Argilés J, et al. Consensus definition of sarcopenia, cachexia and pre-cachexia: Joint document elaborated by Special Interest Groups (SIG) 'cachexia-Anorexia in chronic wasting diseases' and 'nutrition in geriatrics'. Clin Nutr. 2010;29:154-159. doi:10.1016/j.clnu.2009. 12.004
9. Morley JE, Abbatecola AM, Argiles JM, et al. Sarcopenia with limited mobility: An international consensus. J Am Med Dir Assoc. 2011;12:403-409. doi:10.1016/j.jamda.2011.04.014
10. Alley DE, Shardell MD, Peters KW, et al. Grip strength cutpoints for the identification of clinically relevant weakness. J Gerontol A Biol Sci Med Sci. 2014;5:559-566
11. Cawthon PM, Peters KW, Shardell MD, et al. Cut-points for low appendicular lean mass that identify older adults with clinically significant weakness. J Gerontol A Biol Sci Med Sci. 2014;5:567-575
12. Studenski SA, Peters KW, Alley DE, et al. The FNIH sarcopenia project: Rationale and study description. J Gerontol A Biol Sci Med Sci. 2014;5:547-558
13. Cummings SR, Nevitt MC, Browner WS, et al. Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group. N Engl J Med. 1995;332:767-773
14. Cauley JA, Lui LY, Ensrud KE, et al. Bone mineral density and the risk of incident nonspinal fractures in black and white women. JAMA. 2005;293:2102-2108
15. Orwoll E, Blank JB, Barrett-Connor E, et al. Design and baseline characteristics of the osteoporotic fractures in men (MrOS) study-A large observational study of the determinants of fracture in older men. Contemp Clin Trials. 2005;26:569-585
16. Blank JB, Cawthon PM, Carrion-Petersen ML, et al. Overview of recruitment for the Osteoporotic Fractures in Men Study (MrOS). Contemp Clin Trials. 2005;26:557-568
17. Dam TT, Ewing S, Ancoli-Israel S, Ensrud K, Redline S, Stone K. Association between sleep and physical function in older men: The osteoporotic fractures in men sleep study. J Am Geriatr Soc. 2008;56:1665-1673. doi:10.1111/j.1532-5415.2008.01846.x
18. Koster A, Visser M, Simonsick EM, et al. Association between fitness and changes in body composition and muscle strength. J Am Geriatr Soc. 2010;58:219-226. doi:10.1111/j.1532-5415.2009.02681.x
19. Kannel WB, Feinleib M, McNamara PM, Garrison RJ, Castelli WP. An investigation of coronary heart disease in families. The Framingham offspring study. Am J Epidemiol. 1979;110:281-290
20. Ferrucci L, Bandinelli S, Benvenuti E, et al. Subsystems contributing to the decline in ability to walk: Bridging the gap between epidemiology and geriatric practice in the InCHIANTI study. J Am Geriatr Soc. 2000;48:1618-1625
21. Härkönen R, Piirtomaa M, Alaranta H. Grip strength and hand position of the dynamometer in 204 Finnish adults. J Hand Surg Br. 1993;18:129-132
22. Guralnik JM, Ferrucci L, Pieper CF, et al. Lower extremity function and subsequent disability: Consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. J Gerontol A Biol Sci Med Sci. 2000;55:M221-M231
23. Hedges LV, Olkin I. Statistical Methods for Meta-Analysis. Orlando, FL: Academic Press; 1985
24. Newman AB, Kupelian V, Visser M, et al. Sarcopenia: Alternative definitions and associations with lower extremity function. J Am Geriatr Soc. 2003;51:1602-1609
25. Manini TM, Clark BC. Dynapenia and aging: An update. J Gerontol A Biol Sci Med Sci. 2012;67:28-40. doi:10.1093/gerona/glr010
26. Goodpaster BH, Carlson CL, Visser M, et al. Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study. J Appl Physiol (1985). 2001;90:2157-2165
27. Visser M, Kritchevsky SB, Goodpaster BH, et al. Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: The health, aging and body composition study. J Am Geriatr Soc. 2002;50:897-904
28. Delbono O. Regulation of excitation contraction coupling by insulinlike growth factor-1 in aging skeletal muscle. J Nutr Health Aging. 2000;4:162-164
29. Vandervoort AA. Aging of the human neuromuscular system. Muscle Nerve. 2002;25:17-25
30. Arango-Lopera VE, Arroyo P, Gutiérrez-Robledo LM, Pérez-Zepeda MU, Cesari M. Mortality as an adverse outcome of sarcopenia. J Nutr Health Aging. 2013;17:259-262. doi:10.1007/s12603-012-0434-0
31. Landi F, Cruz-Jentoft AJ, Liperoti R, et al. Sarcopenia and mortality risk in frail older persons aged 80 years and older: Results from ilSIRENTE study. Age Ageing. 2013;42:203-209. doi:10.1093/ageing/afs194
32. Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care. J Gerontol A Biol Sci Med Sci. 2004;59:255-263
33. Riley RD, Lambert PC, Abo-Zaid G. Meta-Analysis of individual participant data: Rationale, conduct, and reporting. BMJ. 2010;340:c221. doi:10.1136/bmj.c221.