Cytotoxic diterpenes from roots of Crossopetalum gaumeri, a Celastraceae species from Yucatan Peninsula

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 9, 2014, Pages 2105-2109

  Miron Lopez, Gumersindo ^a   Bazzocchi, Isabel L ^b   Jimenez Diaz, Ignacio A ^b   Moujir, Laila M ^b   Quijano Quiñones, Ramiro ^a   Quijano, Leovigildo ^c   Mena Rejon, Gonzalo J ^a  

^a UNIVERSIDAD AUTÓNOMA DE YUCATÁN   (Mexico)

^b UNIVERSIDAD DE LA LAGUNA   (Spain)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Celastraceae; Crossopetalum; Cytotoxicity; Podocarpane; Yucat n

Indexed keywords

ANTINEOPLASTIC AGENT; CROSSOGUMERIN A; CROSSOGUMERIN B; CROSSOGUMERIN C; CROSSOGUMERIN D; CROSSOPETALUM GAUMERI EXTRACT; CYRTOPHYLLONE B; DEMETHYLCRYPTOJAPONOL; DITERPENE; DITERPENE DERIVATIVE; FERRUGINOL; NIMBIOL; PLANT EXTRACT; SALVADORIOL; SUGIOL; UNCLASSIFIED DRUG; CYTOTOXIC AGENT; DACTINOMYCIN;

AGMK CELL; ARTICLE; CELASTRACEAE; CROSSOPETALUM GAUMERI; CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; DRUG SELECTIVITY; HELA CELL; HEP 2 CELL; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; HYDROGEN BOND; IC 50; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; TUMOR CELL LINE; VERO CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; HELA CELL LINE; HEP 2 CELL LINE; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; IC50; MEXICO; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; VERO CELL LINE; ANIMAL; CHEMISTRY; CHLOROCEBUS AETHIOPS; ISOLATION AND PURIFICATION; NEOPLASMS;

CELASTRACEAE; CERCOPITHECUS AETHIOPS; CROSSOPETALUM; CROSSOPETALUM GAUMERI;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELASTRACEAE; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; DITERPENES; HELA CELLS; HUMANS; NEOPLASMS; PLANT ROOTS; VERO CELLS;

EID: 84899066831     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.03.051     Document Type: Article

References (19)

1. A.G. González, I.L. Bazzocchi, I.A. Jiménez, and L. Moujir Atta-ur-Rahman Natural Products Chemistry, Bioactive Natural Products (Part D) Vol. 23 2000 Elsevier Science Publisher The Netherlands 649
2. X.A. Domínguez, R. Franco, J.B. Alcorn, S. García, and Z.D.A. Ortega Rev. Latinoam. Quim. 15 1984 42
3. B.M. Tincusi, I.A. Jiménez, A.G. Ravelo, and R. Missico J. Nat. Prod. 61 1998 1520
4. A. Ankli, J. Heilmann, M. Heinrich, and O. Sticher Phytochemistry 54 2000 531
5. I.A. Jiménez, I.L. Bazzocchi, M.J. Núñez, T. Mukainaka, H. Tokuda, H. Nishino, T. Konoshima, and A.G. Ravelo J. Nat. Prod. 66 2003 1047
6. C.R. Mendoza, I.A. Jiménez, H. Tokuda, H. Kushida, and I.L. Bazzocchi Chem. Biodivers. 2 2005 286
7. F.M. Rodríguez, N.R. Perestelo, I.A. Jimenez, and I.L. Bazzocchi Helv. Chim. Acta 92 2009 188
8. M.J. Núñez, M.L. Kennedy, I.A. Jiménez, and I.L. Bazzocchi Tetrahedron 67 2011 3030
9. M.J. Núñez, C.P. Reyes, I.A. Jiménez, H. Hayashi, H. Tokuda, and I.L. Bazzocchi Phytochemistry 72 2011 385
10. C.R. Enzell, and I. Wahlberg Acta Chem. Scand. 24 1970 2498
11. W.L. Meyer, G.B. Clemans, and R.A. Manning J. Org. Chem. 40 1975 3686
12. J. Hueso-Rodríguez, M. Jimeno, B. Rodríguez, G. Savona, and M. Bruno Phytochemistry 22 1983 2005
13. X. Tian, Z. Min, N. Xie, Y. Lei, Z. Tian, Q. Zheng, R. Xu, T. Tanaka, M. Linuma, and M. Mizuno Chem. Pharm. Bull. 41 1993 1415
14. L. Moujir, A.M. Gutiérrez-Navarro, L.S. Andrés, and J.G. Luís Phytother. Res. 10 1996 172
15. L.M. Moujir, A.M.L. Seca, L. Araujo, A.M.S. Silva, and M. Carmo Barreto Fitoterapia 82 2011 225
16. L.Y. Wang, J. Wu, Z. Yang, X.J. Wang, Y. Fu, S.Z. Liu, H.M. Wang, W.L. Zhu, H.Y. Zhang, and W.M. Zhao J. Nat. Prod. 76 2013 745
17. A. Yajima, A. Yamaguchi, F. Saitou, T. Nukada, and G. Yabuta Tetrahedron 63 2007 1080
18. G. Wei, L.H. Matthew, H. Luqi, C. Guanghong, W. Xueyong, K. Jianqiang, Y. Bin, and J.P. Reuben Org. Lett. 11 2009 5170
19. The C log P values were calculated using the computer program ChemDraw Ultra ver. 12.0.2.1076. The C log P algorithm incorporated in the ChemDraw software is licensed from BioByte Corporation (http://www.biobyte.com).