Basic Fibroblast Growth Factor (bFGF) facilitates differentiation of adult dorsal root ganglia-derived neural stem cells toward Schwann cells by binding to FGFR-1 through MAPK/ERK activation

Journal of Molecular Neuroscience

Volumn 52, Issue 4, 2014, Pages 538-551

  Gu, Yun ^a   Xue, Chenbin ^a   Zhu, Jianbin ^a   Sun, Hualin ^a   Ding, Fei ^a   Cao, Zheng ^a   Gu, Xiaosong ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Basic fibroblast growth factor (bFGF); Differentiation; Dorsal root ganglia neural stem cells (DRG NSCs); Fibroblast growth factor receptor 1 (FGFR 1); MAPK ERK signal pathway; Schwann cells (SCs)

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; NEU DIFFERENTIATION FACTOR; NEUREGULIN 1BETA; UNCLASSIFIED DRUG; FGFR1 PROTEIN, RAT; NEUREGULIN BETA; SMALL INTERFERING RNA;

ADULT; ANIMAL CELL; ARTICLE; COCULTURE; CONTROLLED STUDY; DORSAL ROOT; ENZYME ACTIVATION; GLIA CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MYELINATION; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEURAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHWANN CELL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ADULT STEM CELL; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; MYELINATED NERVE; PHYSIOLOGY; PRIMARY CELL CULTURE; SPINAL GANGLION; SPRAGUE DAWLEY RAT;

ADULT STEM CELLS; ANIMALS; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; FIBROBLAST GROWTH FACTOR 2; GANGLIA, SPINAL; MAP KINASE SIGNALING SYSTEM; NERVE FIBERS, MYELINATED; NERVE GROWTH FACTOR; NEURAL STEM CELLS; NEUREGULIN-1; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RNA, SMALL INTERFERING; SCHWANN CELLS;

EID: 84899050718     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0109-2     Document Type: Article

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