The effect of procyanidin on expression of STAT1 in type 2 diabetes mellitus SD rats with focal cerebral ischemia

Neuroendocrinology Letters

Volumn 35, Issue 1, 2014, Pages 68-72

  Song, Cheng Guang ^a   Yang, Xin ^a   Min, Lian Qiu ^b   Liu, Chang Xi ^a   Zhao, Chuan Sheng ^c  

^a Benxi Central Hospital of China Medical University   (China)

^b JINZHOU MEDICAL UNIVERSITY   (China)

^c CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Cerebral ischemia; JAK STAT; Procyanidin; STAT1; Type 2 diabetes mellitus

Indexed keywords

PROCYANIDIN; STAT1 PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN TISSUE; COMPARATIVE STUDY; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; RAT; SHAM PROCEDURE;

ANIMALS; APOPTOSIS; BIFLAVONOIDS; BRAIN ISCHEMIA; CATECHIN; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; JANUS KINASES; MALE; NEUROPROTECTIVE AGENTS; PROANTHOCYANIDINS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR;

EID: 84898998656     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Ahlenius H, Devaraju K, Monni E, Oki K, Wattananit S, Darsalia V, et al. (2012). Adaptor protein LNK is a negative regulator of brain neural stem cell proliferation after stroke. J Neurosci. 32: 5151-5164.
2. Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H (1986). Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke. 17:472-476. (Pubitemid 16085691)
3. Cao GF, Yang QD, Yuan CG, Gu WP, Li HY (2006). Expression and phosphorylation of signal transduction and activator of transcription 1 following focal cerebral ischemic reperfusion. Chin J Clin Rehabil. 10:76-78.
4. Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC (2001). Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke. 32:2426-2432. (Pubitemid 32954818)
5. Chin YE, Kitagawa M, Kuida K, Flavell RA, Fu XY (1997). Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol Cell Biol. 17:5328-5337. (Pubitemid 27357631)
6. Doeppner TR, Bretschneider E, Doehring M, Segura I, Sentürk A, Acker-Palmer A, et al. (2011). Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia. Acta Neuropathol. 122:429-442.
7. Facino RM, Carini M, Aldini G, Berti F, Rossoni G, Bombardelli E, et al. (1999). Diet enriched with procyanidins enhances antioxidants activity and reduces myocardial post-ischaemic damage in rats. Life Sci. 64:627-642. (Pubitemid 29083176)
8. Folch Puy E, Granell S, Dagom JC, lovanna JL, Ciosa D (2006). Pancreatitis-associated protein I suppresses NF-kappa B activation through a JAK/STAT-mediated mechanism in epithelial cells. J Immunol. 176:3774-3779. (Pubitemid 43364025)
9. Guo XH, Liu ZH, Li H, Li LS (2002). Type 2 diabetes mellitus induced by diets and its features of renal involvement in rat. Chin J Diabetes. 10:290-294.
10. Klampfer L (2006). Signal transducers and activators of transcription (STATs): Novel targets of chemopreventive and chemotherapeutic drugs. Curr Cancer Drug Targets. 6:107-121.
11. Ramana CV, Grammatikakis N, Chernov M, Nguyen H, Goh KC, Williams BR, et al. (2000). Regulation of c-myc expression by IFNthrough Stat1 dependent and-independent pathways. EMBO J. 19:263-272. (Pubitemid 30042708)
12. Shouda T, Hiraoka K, Komiya S, Hamada T, Zenmyo M, Iwasaki H, et al. (2006). Suppression of IL-6 production and proliferation by blocking STAT3 activation in malignant soft tissue tumor cells. Cancer Lett. 231:176-184. (Pubitemid 43038728)
13. Sinatra ST, DeMarco J (1995). Free radicals, oxidative stress, oxidized low density lipoprotein (LDL), and the heart: Antioxidants and strategies to limit cardiovascular damage. Conn Med. 59: 579-588.
14. Stephanou A, Brar BK, Knight RA, Latchman DS (2000). Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters. Cell Death Differ. 7:329-330. (Pubitemid 30192982)
15. Stephanou A, Scarabelli TM, Brar BK, Nakanishi Y, Matsumura M, Knight RA, et al. (2001). Induction of apoptosis and Fas receptor/ Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701. J Biol Chem. 276:28340-28347.
16. Sun SL, LI TJ, Yang PY, Qiu Y, Rui YC (2007). Modulation of signal transducers and activators of transcription (STAT) factor pathways during focal cerebral ischemia: A gene expression array study in rat hippocampus after middle cerebral artery occlusion. Clin Exp Pharmacol Physiol. 34:1097-1101.
17. Takagi Y, Harada J, Chiarugi A, Moskowitz MA (2002). STATI is activated in neurons after ischemia and contributes to ischemic brain injury. J Cereb Blood Flow Metab. 22:1311-1318. (Pubitemid 35285088)
18. West DA, Valentim LM, Lythgoe MF, Stephanou A, Proctor E, van der Weerd L, et al. (2004). MR image-guided investigation of regional signal transducers and activators of transcription-1 activation in a rat model of focal cerebral ischemia. Neuroscience. 127:333-339. (Pubitemid 38950648)
19. Yamaguchi F, Yoshimura Y, Nakazawa H, Ariga T (1999). Free radical scavenging activity of grape seed extract and antioxidants by electron spin resonance spectrometry in an H(2)0(2)/NaOH/ DMSO system. J Agric Food Chem. 47:2544-2548. (Pubitemid 29396318)