The GTPase-deficient Rab27A(Q78L) mutant inhibits melanosome transport in melanocytes through Trapping of Rab27A effector protein Slac2-a/Melanophilin in their cytosol: Development of a novel melanosome-targeting tag

Journal of Biological Chemistry

Volumn 289, Issue 16, 2014, Pages 11059-11067

  Ishida, Morié ^a   Arai, Saki P ^a   Ohbayashi, Norihiko ^a   Fukuda, Mitsunori ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY;

CYTOSOLS; GTPASE ACTIVITY;

BIOLOGY;

CELL PROTEIN; HYBRID PROTEIN; MELANOPHILIN; MST RAB27A FUSION PROTEIN; MUTANT PROTEIN; PROTEIN SLAC2A; RAB27A PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL AGGREGATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INHIBITION KINETICS; MELANOCYTE; MELANOSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; PROTEIN TRANSPORT; WILD TYPE;

LOW MOLECULAR WEIGHT G PROTEINS; MELANOGENESIS; MEMBRANE TRAFFICKING; PROTEIN TARGETING; RAB; SMALL GTPASES; SUBCELLULAR ORGANELLES;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; MELANOSOMES; MICE; MUTATION, MISSENSE; PIEBALDISM; PROTEIN TRANSPORT; RAB GTP-BINDING PROTEINS;

EID: 84898972966     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.552281     Document Type: Article

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