N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of mycobacterium tuberculosis

Journal of Infectious Diseases

Volumn 209, Issue 7, 2014, Pages 1045-1054

  Hansen, Jesse M ^a   Golchin, Solmaz A ^a   Veyrier, Frédéric J ^b,c,d   Domenech, Pilar ^a   Boneca, Ivo G ^c,d   Azad, Abul K ^e   Rajaram, Murugesan V S ^e   Schlesinger, Larry S ^e   Divangahi, Maziar ^a,f   Reed, Michael B ^a,f   Behr, Marcel A ^a,f  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b Département Infection et Epidémiologie Infection Bactériennes Invasives   (France)

^c INSTITUT PASTEUR   (France)

^d INSERM   (France)

^e OHIO STATE UNIVERSITY   (United States)

^f MCGILL UNIVERSITY   (Canada)

Author keywords

N acetyl muramic acid hydroxylase, NamH; N glycolyl MDP; NOD2; tuberculosis

Indexed keywords

MURAMYL DIPEPTIDE; MYCOLIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CELL WALL; BACTERIAL GENE; BACTERIAL LOAD; BACTERIAL REPRODUCTION; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; C57BL 6 MOUSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EX VIVO STUDY; HUMAN; HUMAN CELL; IMMUNOGENICITY; IN VIVO STUDY; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NAMH GENE; NONHUMAN; PRIORITY JOURNAL; TUBERCULOSIS;

N-ACETYL MURAMIC ACID HYDROXYLASE, NAMH; N-GLYCOLYL MDP; NOD2; TUBERCULOSIS;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ANIMALS; BACTERIAL LOAD; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENE DELETION; HUMANS; MACROPHAGES; MICE; MICE, INBRED C57BL; MIXED FUNCTION OXYGENASES; MYCOBACTERIUM TUBERCULOSIS; PEPTIDOGLYCAN; PROTEIN PROCESSING, POST-TRANSLATIONAL; SURVIVAL ANALYSIS; TUBERCULOSIS, PULMONARY; VIRULENCE;

EID: 84898968769     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jit622     Document Type: Article

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