Genetic variation in COMT activity impacts learning and dopamine release capacity in the striatum

Learning and Memory

Volumn 21, Issue 4, 2014, Pages 205-214

  Simpson, Eleanor H ^a,b   Morud, Julia ^c   Winiger, Vanessa ^a   Biezonski, Dominik ^a   Zhu, Judy P ^a   Bach, Mary Elizabeth ^a   Malleret, Gael ^d   Polan, H Jonathan ^e   Ng Evans, Scott ^f   Phillips, Paul E M ^f   Kellendonk, Christoph ^a   Kandel, Eric R ^a,b,g  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d UNIVERSITÉ LYON 1   (France)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; VALINE; CATECHOL METHYLTRANSFERASE; COMT PROTEIN, MOUSE; DOPAMINE TRANSPORTER; TYROSINE 3 MONOOXYGENASE;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; COMT GENE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE METABOLISM; DOPAMINE RELEASE; FEMALE; GENE; GENE OVEREXPRESSION; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC VARIABILITY; LEARNING; MALE; MENTAL DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; SIGNAL TRANSDUCTION; SYNAPSE; TRANSGENIC MOUSE; WORKING MEMORY; ANIMAL; C57BL MOUSE; COMPULSION; FOREBRAIN; GENETICS; IMPULSIVENESS; LEARNING DISORDER; MEMORY DISORDER; METABOLISM; MOTOR ACTIVITY; NEUROPSYCHOLOGICAL TEST; PHYSIOLOGY; SHORT TERM MEMORY; VALIDATION STUDY;

ANIMALS; CATECHOL O-METHYLTRANSFERASE; COGNITION; COMPULSIVE BEHAVIOR; CORPUS STRIATUM; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; IMPULSIVE BEHAVIOR; LEARNING; LEARNING DISORDERS; MALE; MEMORY DISORDERS; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, ANIMAL; MOTOR ACTIVITY; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, GENETIC; PROSENCEPHALON; TYROSINE 3-MONOOXYGENASE;

EID: 84898959800     PISSN: 10720502     EISSN: 15495485     Source Type: Journal    
DOI: 10.1101/lm.032094.113     Document Type: Article

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