First finding of Ostreopsis cf. ovata toxins in marine aerosols

Environmental Science and Technology

Volumn 48, Issue 6, 2014, Pages 3532-3540

  Ciminiello, Patrizia ^a   Dell'Aversano, Carmela ^a   Iacovo, Emma Dello ^a   Fattorusso, Ernesto ^a   Forino, Martino ^a   Tartaglione, Luciana ^a   Benedettini, Gioia ^b   Onorari, Marzia ^b   Serena, Fabrizio ^b   Battocchi, Cecilia ^c   Casabianca, Silvia ^c   Penna, Antonella ^c,d  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b Agenzia Regionale Protezione Ambientale della Toscana (ARPAT)   (Italy)

^c UNIVERSITY OF URBINO   (Italy)

^d INSTITUTE OF MARINE SCIENCES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; POLYMERASE CHAIN REACTION; POLYOLS; TOXIC MATERIALS;

ALGAL SAMPLES; INHALATION EXPOSURE; MARINE AEROSOLS; MARINE TOXINS; MEDITERRANEAN AREAS; PCR ASSAY; RESPIRATORY ILLNESS; SMALL SCALE;

AEROSOLS;

MARINE TOXIN; PALYTOXIN; ACRYLAMIDE DERIVATIVE; AEROSOL; SEA WATER;

AEROSOL; ALGA; DINOFLAGELLATE; MARINE ATMOSPHERE; PUBLIC HEALTH; TOXIC ORGANISM; TOXICOLOGY; TOXIN;

AEROSOL; ARTICLE; DINOFLAGELLATE; EXPOSURE; HUMAN; NONHUMAN; OSTREOPSIS OVATA; POLYMERASE CHAIN REACTION SYSTEM; RESPIRATORY TRACT DISEASE; SEASHORE; ANALYSIS; CHEMISTRY; ENVIRONMENTAL MONITORING; GENETICS; ISOLATION AND PURIFICATION; ITALY; MARINE BIOLOGY; PROCEDURES;

ITALY; MEDITERRANEAN SEA; TUSCANY;

ACRYLAMIDES; AEROSOLS; DINOFLAGELLIDA; ENVIRONMENTAL MONITORING; ITALY; MARINE BIOLOGY; MARINE TOXINS; SEAWATER;

EID: 84898943506     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es405617d     Document Type: Article

References (63)

1. Mangialajo, L.; Ganzin, N.; Accoroni, S.; Asnaghi, V.; Blanfuné, A.; Cabrini, M.; Cattaneo-Vietti, R.; Chavanon, F.; Chiantore, M.; Cohu, S.; Costa, E.; Fornasaro, D.; Grossel, H.; Marco-Miralles, F.; Masó, M.; Reñé, A.; Rossi, A. M.; Montserrat Sala, M.; Thibaut, T.; Totti, C.; Vila, M.; Lemée, R. Trends in Ostreopsis proliferation along the Northern Mediterranean coasts Toxicon 2011, 57, 408-420
2. Tubaro, A.; Durando, P.; Del Favero, G.; Ansaldi, F.; Icardi, G.; Deeds, J. R.; Sosa, S. Case definitions for human poisonings postulated to palytoxins exposure Toxicon 2011, 57, 478-495
3. Sansoni, G.; Borghini, B.; Camici, G.; Casotti, M.; Righini, P.; Rustighi, C. Fioriture algali di Ostreopsis ovata (Gonyaulacales: Dinophyceae): un problema emergente Biologia Ambientale 2003, 17, 17-23
4. Durando, P.; Ansaldi, F.; Oreste, P.; Moscatelli, P.; Marensi, L.; Grillo, C.; Gasparini, R.; Icardi, G. Ostreopsis ovata and human health: epidemiological and clinical features of respiratory syndrome outbreaks from a two year syndromic surveillance, 2005-2006, in north-west Italy. Euro Surveill. 2007, 12 (23). http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=3212 (accessed March 7, 2014).
5. Ciminiello, P.; Dell'Aversano, C.; Dello Iacovo, E.; Fattorusso, E.; Forino, M.; Tartaglione, L.; Yasumoto, T.; Battocchi, C.; Giacobbe, M.; Amorim, A.; Penna, A. Investigation of toxin profile of Mediterranean and Atlantic strains of Ostreopsis cf. siamensis (Dinophyceae) by liquid chromatography-high resolution mass spectrometry Harmful Algae 2013, 23, 19-27
6. Ciminiello, P.; Dell'Aversano, C.; Fattorusso, E.; Forino, M.; Magno, G. S.; Tartaglione, L.; Grillo, C.; Melchiorre, N. The Genoa 2005 outbreak. Determination of putative palytoxin in Mediterranean Ostreopsis ovata by a new liquid chromatography tandem mass spectrometry method Anal. Chem. 2006, 78, 6153-6159
7. Ciminiello, P.; Dell'Aversano, C.; Fattorusso, E.; Forino, M.; Tartaglione, L.; Grillo, C.; Melchiorre, N. Putative palytoxin and its new analogue, ovatoxin-a, in Ostreopsis ovata collected along the Ligurian coasts during the 2006 toxic outbreak J. Am. Soc. Mass Spectrom. 2008, 19, 111-120
8. Ciminiello, P.; Dell'Aversano, C.; Dello Iacovo, E.; Fattorusso, E.; Forino, M.; Grauso, L.; Tartaglione, L.; Guerrini, F.; Pistocchi, R. Complex palytoxin-like profile of Ostreopsis ovata. Identification of four new ovatoxins by high-resolution liquid chromatography/mass spectrometry Rapid Commun. Mass Spectrom. 2010, 24, 2735-2744
9. n characterization of ovatoxin-f, a new palytoxin congener Chem. Res. Toxicol. 2012, 25, 1243-1252
10. Uemura, D.; Ueda, K.; Hirata, Y.; Naoki, H.; Iwashita, T. Further studies on palytoxin. II. Structure of palytoxin Tetrahedron Lett. 1981, 22, 2781-2784
11. Moore, R. E.; Bartolini, G. Structure of palytoxin J. Am. Chem. Soc. 1981, 103, 2491-2494
12. Ciminiello, P.; Dell'Aversano, C.; Dello Iacovo, E.; Fattorusso, E.; Forino, M.; Grauso, L.; Tartaglione, L.; Guerrini, F.; Pezzolesi, L.; Pistocchi, R.; Vanucci, S. Isolation and structure elucidation of ovatoxin-a, the major toxin produced by Ostreopsis ovata J. Am. Chem. Soc. 2012, 134 (3) 1869-1875
13. Ciminiello, P.; Dell'Aversano, C.; Dello Iacovo, E.; Fattorusso, E.; Forino, M.; Grauso, L.; Tartaglione, L. Stereochemical studies on ovatoxin-a Chem.-Eur. J. 2012, 18 (52) 16836-16843
14. n fragmentation pattern of palytoxin as template to gain new insights into ovatoxin-a structure. The key role of calcium in MS behavior of palytoxins J. Am. Soc. Mass. Spectrom. 2012, 23 (5) 952-963
15. Munday, R. Palytoxin toxicology: Animal studies Toxicon 2011, 57, 470-477
16. Ito, E.; Yasumoto, T. Toxicological evaluation on palytoxin and ostreocin-D administered to mice by three different routes Toxicon 2009, 54, 244-251
17. Crinelli, R.; Carloni, E.; Giacomini, E.; Penna, A.; Dominici, S.; Battocchi, C.; Ciminiello, P.; Dell'Aversano, C.; Fattorusso, E.; Forino, M.; Tartaglione, L.; Magnani, M. Palytoxin and an Ostreopsis toxin extract increase the levels of mRNAs encoding inflammation-related proteins in human macrophages via p38 MAPK and NF-κB PLoS One 2012, 7 (6) e38139
18. Fleming, L. E.; Kirkpatrick, B.; Backer, L. C.; Walsh, C. J.; Nierenberg, K.; Clark, J.; Reich, A.; Hollenbeck, J.; Benson, J.; Cheng, Y. S.; Naar, J.; Pierce, R.; Bourdelais, A. J.; Abraham, W. M.; Kirkpatrick, G.; Zaias, J.; Wanner, A.; Mendes, E.; Shalat, S.; Hoagland, P.; Stephan, W.; Bean, J.; Watkins, S.; Clarke, T.; Byrne, M.; Baden, D. G. Review of Florida red tide and human health effects Harmful Algae 2011, 10, 224-233
19. Backer, L. C.; McNeel, S. V.; Barber, T.; Kirkpatrick, B.; Williams, C.; Irvin, M.; Zhou, Y.; Johnson, T. B.; Nierenberg, K.; Aubel, M.; LePrell, R.; Chapman, A.; Foss, A.; Corum, S.; Hill, V. R.; Kieszak, S. M.; Cheng, Y. S. Recreational exposure to microcystins during algal blooms in two California lakes Toxicon 2010, 55, 909-921
20. Cheng, Y. S.; Zhou, Y.; Irvin, C. M.; Kirkpatrick, B.; Backer, L. C. Characterization of aerosols containing microcystin Mar. Drugs 2007, 5, 136-50
21. Deeds, J. R.; Schwartz, M. D. Human risk associated with palytoxin exposure Toxicon 2010, 56 (2) 150-162
22. Casabianca, S.; Casabianca, A.; Riobó, P.; Franco, J.; Vila, M.; Penna, A. Quantification of the toxic dinoflagellate Ostreopsis spp. by qPCR assay in marine aerosol Environ. Sci. Technol. 2013, 47, 3788-3795
23. Battocchi, C.; Totti, C.; Vila, M.; Masò, M.; Capellacci, S.; Accoroni, S.; René, A.; Scardi, M.; Penna, A. Monitoring toxic microalgae Ostreopsis (dinoflagellate) species in coastal waters of the Mediterranean Sea using molecular PCR-based assay combined with light microscopy Mar. Pollut. Bull. 2010, 60 (7) 1074-1084
24. Steidinger, K.; Tangen, K. Dinoflagellates. In Identifying Marine Phytoplankton; Tomas, C., Ed.; Academic Press: New York, 1997; pp 387-584.
25. Adachi, M.; Sako, Y.; Ishida, Y. Restriction fragment length polymorphism of ribosomal DNA internal transcribed spacer and 5.8S regions in Japanese Alexandrium species (Dinophyceae) J. Phycol. 1994, 30, 857-863
26. Penna, A.; Bertozzini, E.; Battocchi, C.; Giacobbe, M. G.; Galluzzi, L.; Garces, E.; Vila, M.; Lugliè, A.; Magnani, M. Monitoring of HAB species in the Mediterranean Sea through molecular techniques J. Plank. Res. 2007, 29, 19-38
27. Taylor, F. J. R. A description of the benthic dinoflagellate associated with maitotoxin and ciguatoxin, including observations on Hawaiian material. In Toxic Dinoflagellate Blooms; Taylor, D. L.; Seliger, H. H., Eds.; Elsevier/North-Holland: New York, 1979; pp 71-76.
28. Kermarec, F.; Dor, F.; Armengaud, A.; Charlet, F.; Kantin, R.; Sauzade, D.; de Haro, L. Health risks related to Ostreopsis ovata in recreational waters Environnement, Risques & Santé 2008, 7, 357-363
29. Abboud-Abi Saab, M. Les dinoflagellés des eaux côtières libanaises. Espèces rares ou nouvelles du phytoplancton marin Leban. Sci. Bull. 1989, 5 (2) 5-16
30. Abboud-Abi Saab, M.; Fakhri, M.; Kassab, M. T.; Matar, N. Seasonal and spatial variations of the dinoflagellate Ostreopsis siamensis in the Lebanese coastal waters (Eastern Mediterranean) Cryptogam.: Algol. 2013, 34 (1) 57-67 2013.
31. Vila, M.; Masó, M.; Sampedro, N.; Illoul, H.; Arín, L.; Garcés, E.; Giacobbe, M. G.; Alvarez, J.; Camp, J. The genus Ostreopsis in recreational waters of the Catalan coast and Balearic Islands (NW Mediterranean sea): Is this the origin of human respiratory difficulties? In Proceedings of the 12th International Conference on Harmful Algae; Moestrup, Ø., Eds.; International Society for the Study of Harmful Algae and Intergovernmental Oceanographic Commission of UNESCO: Copenhagen, 2008; pp 334-336.
32. Vila, M.; Arin, L.; Battocchi, C.; Bravo, I.; Fraga, S.; Penna, A.; Reñé, A.; Riobó, P.; Rodriguez, F.; Sala, M.; Camp, J.; de Torres, M.; Franco, J. M. Management of Ostreopsis blooms in recreational waters along the Catalan coast (NW Mediterranean Sea): cooperation between a research project and a monitoring program Cryptogam.: Algol. 2012, 33, 143-152
33. Tognetto, L.; Bellato, S.; Moro, I.; Andreoli, C. Occurrence of Ostreopsis ovata (Dinophyceae) in the Tyrrhenian sea during Summer 1994 Bot. Mar. 1995, 38, 291-295
34. Vila, M.; Garcés, E.; Masó, M. Potentially toxic epiphytic dinoflagellates assemblages on macroalgae in the NW Mediterranean Aquat. Microb. Ecol. 2001, 26, 51-60
35. Penna, A.; Vila, M.; Fraga, S.; Giacobbe, M. G.; Andreoni, F.; Riobó, P.; Vernesi, C. Characterization of Ostreopsis and Coolia (Dinophyceae) isolates in the Western Mediterranean Sea based on morphology, toxicity and internal transcribed spacer 5.8S rDNA sequences J. Phycol. 2005, 41, 212-225
36. Ismael, A.; Halim, Y. Potentially harmful Ostreopsis spp. in the coastal waters of Alexandria-Egypt Medit. Mar. Sci. 2012, 13 (2) 208-212
37. Rustighi, C.; Casotti, M. Fioriture tossiche di Ostreopsis ovata sul litorale Apuano Rapp. ISTISAN 2005, 05/29, 118-122
38. Monti, M.; Minocci, M.; Beran, A.; Ives, L. First record of Ostreopsis cfr. ovata on macroalgae in the Northern Adriatic Sea Mar. Pollut. Bull. 2007, 54, 598-601
39. Honsell, G.; Bonifacio, A.; De Bortoli, M.; Penna, A.; Battocchi, C.; Ciminiello, P.; Dell'Aversano, C.; Fattorusso, E.; Sosa, S.; Yasumoto, T.; Tubaro, A. New insights on cytological and metabolic features of Ostreopsis cf. ovata Fukuyo (Dinophyceae): A multidisciplinary approach PLoS One 2013, 8 (2) e57291
40. Tichadou, L.; Glaizal, M.; Armengaud, A.; Grossel, H.; Lemée, R.; Kantin, R.; Lasalle, J. L.; Drouet, G.; Rambaud, L.; Malfait, P.; de Haro, L. Health impact of unicellular algae of the Ostreopsis genus blooms in the M editerranean Sea: Experience of the French Mediterranean coast surveillance network from 2006 to 2009 Clin. Toxicol. 2010, 48 (8) 839-844
41. Barroso García, P.; Rueda de la Puerta, P.; Parrón Carreño, T.; Marín Martínez, P.; GuillénEnrí quez, J. Brote con síntomas respiratorios en la provincia de Almería por una posible exposición a microalgas tóxicas Gac. Sanit. 2008, 22, 578-584
42. Turki, S.; Harzallah, A.; Sammari, C. Occurrence of harmful dinoflagellates in two different Tunisian ecosystems: the lake of Bizerte and the Gulf of Gabes Cah. Biol. Mar. 2006, 47, 253-259
43. Totti, C.; Accoroni, S.; Cerino, F.; Cucchiari, E.; Romagnoli, T. Ostreopsis ovata bloom along the Conero Riviera (northern Adriatic Sea): relationships with environmental conditions and substrata Harmful Algae 2010, 9, 233-239
44. Accoroni, S.; Romagnoli, T.; Colombo, F.; Pennesi, C.; Di Camillo, C. G.; Marini, M.; Battocchi, C.; Ciminiello, P.; Dell'Aversano, C.; Dello Iacovo, E.; Fattorusso, E.; Tartaglione, L.; Penna, A.; Totti, C. Ostreopsis cf. ovata bloom in the northern Adriatic Sea during summer 2009: Ecology, molecular characterization and toxin profile Mar. Pollut. Bull. 2011, 62 (11) 2512-9
45. Cohu, S.; Thibaut, T.; Mangialajo, L.; Labat, J. P.; Passafiume, O.; Blanfuné, A.; Simon, N.; Cottalorda, J. M.; Lemée, R. Occurrence of the toxic dinoflagellate Ostreopsis cf. ovata in relation with environmental factors in Monaco (NW Mediterranean) Mar. Pollut. Bull. 2011, 62, 2681-2691
46. Amorim, A.; Veloso, V.; Penna, A. First detection of Ostreopsis cf. siamensis in Portuguese coastal waters Harmful Algal News 2010, 42, 6-7
47. Casavola, N.; Troncone, A.; Rizzi, E.; Favale, M. G.; Bello, G. Microalghe marine tossiche nella provincia di Bari:danni ambientali, ittiofaunistici, evidenze epidemiologiche. In Diffusione delle fioriture algali tossiche nelle acque italiane: gestione del rischio ed evidenze epidemiologiche; Mattei, D.; Melchiorre, S.; Messineo, V.; Bruno, M., Eds.; Rapporti Istisan 05/29, Istituto Superiore di Sanità: Rome, 2005; pp 92-97.
48. Gallitelli, M.; Ungaro, N.; Addante, L. M.; Gentiloni Silver, N.; Sabba, C. Respiratory illness as a reaction to tropical algal blooms occurring in a temperate climate JAMA, J. Am. Med. Assoc. 2005, 293, 2599-2600
49. Pfannkuchen, M.; Godrijan, J.; Pfannkuchen, D. M.; Iveša, L.; Kružić, P.; Ciminiello, P.; Dell'Aversano, C.; Dello Iacovo, E.; Fattorusso, E.; Forino, M.; Tartaglione, L.; Godrijan, M. Toxin-producing Ostreopsis cf. ovata are likely to bloom undetected along coastal areas Environ. Sci. Technol. 2012, 46 (10) 5574-82
50. Bottalico, A.; Milella, P.; Felicini, G. P. Fioritura di Ostreopsis spp. (Dinophyta) nel porto di Otranto. In Abstract Book of the Riunione Scientifica Annuale del Gruppo di Lavoro per l'Algologia - Società Botanica Italiana, Chioggia (VE), Italy, 2002, p 21.
51. Ostreopsis ovata, Coolia monotis e Prorocentrum lima lungo le coste della Regione Basilicata; Monitoraggio di Ostreopsis ovata e altre microalghe potenzialmente tossiche tossiche lungo le aree marino costiere italiane. Anno 2010. ISPRA, Rapporti 148/2011. http://www.isprambiente.gov.it/contentfiles/ 00010300/10382-rapporto-148-2011.pdf/view (accessed March 7, 2014).
52. Aligizaki, K.; Nikolaidis, G. The presence of the potentially toxic genera Ostreopsis and Coolia (Dinophyceae) in the North Aegean Sea, Greece Harmful Algae 2006, 5, 717-730
53. Aligizaki, K.; Katikoub, P.; Nikolaidisa, G.; Panou, A. First episode of shellfish contamination by palytoxin-like compounds from Ostreopsis species (Aegean Sea, Greece) Toxicon 2008, 51, 418-427
54. Tavolo Tecnico Regionale sulle Acque. http://www.artasicilia.eu/old-site/ web/servizio-7-dra/site/3acque/Documenti/Tavolo-tecnico- Scheda%20tecnica%20Ostreopsis.pdf (accessed March 7, 2014).
55. Zingone, A.; Siano, R.; D'Alelio, D.; Sarno, D. Potentially toxic and harmful microalgae from coastal waters of the Campania region (Tyrrhenian Sea, Mediterranean Sea) Harmful Algae 2006, 5, 321-337
56. David, H.; Moita, M. T.; Laza-Martínez, A.; Silva, A.; Mateus, M.; de Pablo, H.; Orive, E. First bloom of Ostreopsis cf. ovata in the continental Portuguese coast Harmful Algal News 2012, 45, 12-13
57. Bennouna, A.; El Attar, J.; Abouabdellah, R.; Palma, S.; Penna, A.; Moita, T. First records of Ostreopsis cf. siamensis in Moroccan Atlantic upwelling waters Harmful Algal News 2010, 42, 1-3
58. Monitoraggio di Ostreopsis ovata lungo le coste della provincia di Sassari nell'estate 2011. Ostreopsis cf. ovata lungo le coste italiane: monitoraggio 2011. ISPRA, Rapporto 173/2012. http://www.isprambiente.gov.it/ files/pubblicazioni/rapporti/Rapporto%20173%20-2012.pdf (accessed March 7, 2014).
59. Monitoraggio di Ostreopsis ovata e altre microalghe potenzialmente tossiche lungo le aree marino costiere Italiane. Anno 2010. ISPRA, Rapporti 148/2011. http://www.isprambiente.gov.it/contentfiles/00010300/10388-rapporto- 148-2011.pdf/view (accessed March 7, 2014).
60. Linee guida gestione del rischio associato alle fioriture di Ostreopsis ovata nelle coste italiane; approved by Consiglio Superiore di Sanità: Rome, May 24, 2007. http://www.salute.gov.it/imgs/C-17-pubblicazioni-641- allegato.pdf (accessed March 7, 2014).
61. Grönkvist, M. J.; Emery, M. J.; Gustafsson, P. M. Mechanisms of ventilation inhomogeneity during vital capacity breaths standing and supine Respir. Physiol. 2002, 129, 345-355
62. Taylor, T. J.; Parker, G. W.; Fajer, A. B.; Mereish, K. A. Non-specific binding of palytoxin to plastic surfaces Toxicol. Lett. 1991, 57 (3) 291-296
63. Ciminiello, P.; Dell'Aversano, C.; Dello Iacovo, E.; Fattorusso, E.; Forino, M.; Tartaglione, L. LC-MS of palytoxin and its analogues: state of the art and future perspectives Toxicon 2011, 57, 376-389