Development of macrolide resistance in mycoplasma pneumoniae-infected Swedish patients treated with macrolides

Scandinavian Journal of Infectious Diseases

Volumn 46, Issue 4, 2014, Pages 315-319

  Nilsson, Anna C ^a   Jensen, Jorgen Skov ^b   Björkman, Per ^a   Persson, Kenneth ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b STATENS SERUM INSTITUT   (Denmark)

Author keywords

Induced macrolide resistance; Mycoplasma pneumoniae

Indexed keywords

AZITHROMYCIN; CEFUROXIME; DOXYCYCLINE; ERYTHROMYCIN; MACROLIDE; RNA 23S; ROXITHROMYCIN; ANTIINFECTIVE AGENT;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BRONCHUS OBSTRUCTION; CHILD; CLINICAL ARTICLE; FATIGUE; FEMALE; FOLLOW UP; HUMAN; HYPOXEMIA; MALE; MYCOPLASMA PNEUMONIA; MYCOPLASMA PNEUMONIAE; PNEUMONIA; POINT MUTATION; POLYMERASE CHAIN REACTION; PYROSEQUENCING; SWEDEN; TREATMENT DURATION; ADOLESCENT; DRUG EFFECTS; EPIDEMIOLOGY; GENETICS; MICROBIOLOGY; MIDDLE AGED; PNEUMONIA, MYCOPLASMA; PRESCHOOL CHILD; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE, BACTERIAL; FEMALE; HUMANS; MACROLIDES; MALE; MIDDLE AGED; MYCOPLASMA PNEUMONIAE; PNEUMONIA, MYCOPLASMA; SWEDEN; YOUNG ADULT;

EID: 84898939792     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365548.2013.866268     Document Type: Article

References (24)

1. GE, McMahan R, Kaiser G, Grayston JT. Mycoplasma pneumoniae in the community. Am J Epidemiol 1971; 93: 55-67.
2. Lind K, Benzon MW, Jensen JS, Clyde WA Jr. A seroepidemiological study of Mycoplasma pneumoniae infections in Denmark over the 50-year period 1946-95. Eur J Epidemiol 1997; 13: 581-6.
3. Nilsson A C, Bjorkman P, Persson K. P olymerase chain reaction is superior to serology for the diagnosis of acute Mycoplasma pneumoniae infection and reveals a high rate of persistent infection. BMC Microbiol 2008; 8: 93.
4. T aylor-Robinson D, Bebear C. A ntibiotic susceptibilities of mycoplasmas and treatment of mycoplasmal infections. J Antimicrob Chemother 1997; 40: 622-30.
5. Morozumi M, Takahashi T, Ubukata K. M acrolide-resistant Mycoplasma pneumoniae: characteristics of isolates and clinical aspects of community-acquired pneumonia. J Infect Chemother 2010; 16: 78-86.
6. Cao B, Zhao CJ, Yin YD, Zhao F, Song SF, Bai L, et al. High prevalence of macrolide resistance in Mycoplasma pneumoniae isolates from adult and adolescent patients with respiratory tract infection in China. Clin Infect Dis 2010; 2: 189-94.
7. C ardinale F, Chironna M, Chinellato I, Principi N, Esposito S. Clinical relevance of Mycoplasma pneumoniae macrolide resistance in children. J Clin Microbiol 2013; 51: 723-4.
8. Principi N, Esposito S. M acrolide-resistant Mycoplasma pneumoniae: its role in respiratory infection. J Antimicrob Chemother 2013; 68: 506-11.
9. Okazaki N, Ohya H, Sasaki T. M ycoplasma pneumoniae isolated from patients with respiratory infection in Kanagawa Prefecture in 1976-2006: emergence of macrolide-resistant strains. Jpn J Infect Dis 2007; 60: 325-6.
10. Liu Y, Ye X, Zhang H, Xu X, Li W, Zhu D, et al. A ntimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China. Antimicrob Agents Chemother 2009; 53: 2160-2.
11. Zhao F, Lv M, Tao X, Huang H, Zhang B, Zhang Z, et a l. Antibiotic sensitivity of 40 Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant isolates from Beijing, China. Antimicrob Agents Chemother 2012; 56: 1108-9.
12. Uldum S A, Bangsborg J M, Gahrn-Hansen B, Ljung R, M ø lvadgaard M, F ø ns Petersen R, et al. Epidemic of Mycoplasma pneumoniae infection in Denmark, 2010 and 2011. Euro Surveill 2012; 2: 17.
13. Spuesens EB, Meijer A, Bierschenk D, Hoogenboezem T, Donker GA, Hartwig NG, et al. Macrolide resistance determination and molecular typing of Mycoplasma pneumoniae in respiratory specimens collected between 1997 and 2008 in the Netherlands. J Clin Microbiol 2012; 50: 1999-2004.
14. Dumke R, von Baum H, Luck P C, Jacobs E. O ccurrence of macrolide-resistant Mycoplasma pneumoniae strains in Germany. Clin Microbiol Infect 2010; 6: 613-6.
15. Yamada M, Buller R, Bledsoe S, Storch GA. R ising rates of macrolide-resistant Mycoplasma pneumoniae in the central United States. Pediatr Infect Dis J 2012; 4: 409-10.
16. Chironna M, Sallustio A, Esposito S, Perulli M, Chinellato I, Di Bari C, et al. Emergence of macrolideresistant strains during an outbreak of Mycoplasma pneumoniae infections in children. J Antimicrob Chemother 2011; 66: 734-7.
17. Foy H M, Kenny G E, Cooney M K, Allan I D. L ong-term epidemiology of infections with Mycoplasma pneumoniae. J Infect Dis 1979; 139: 681-7.
18. Smith C B, Friedewald W T, Chanock R M. S hedding of Mycoplasma pneumoniae after tetracycline and erythromycin therapy. N Engl J Med 1967; 276: 1172-5.
19. Nilsson AC, Bjorkman P, Welinder-Olsson C, Widell A, Persson K. Clinical severity of Mycoplasma pneumoniae (MP) infection is associated with bacterial load in oropharyngeal secretions but not with MP genotype. BMC Infect Dis 2010; 10: 39.
20. Jensen JS, Bradshaw CS, Tabrizi SN, Fairley CK, Hamasuna R. Azithromycin treatment failure in Mycoplasma genitaliumpositive patients with nongonococcal urethritis is associated with induced macrolide resistance. Clin Infect Dis 2008; 47: 1546-53.
21. Bradshaw C S, Jensen J S, Tabrizi S N, Read TR, Garland S M, Hopkins CA, et al. Azithromycin failure in Mycoplasma genitalium urethritis. Emerg Infect Dis 2006; 12: 1149-52.
22. Cardinale F, Chironna M, Dumke R, Binetti A, Daleno C, Sallustio A, et al. Macrolide-resistant Mycoplasma pneumoniae in paediatric pneumonia. Eur Respir J 2011; 37: 1522-4.
23. Kawai Y, Miyashita N, Yamaguchi T, Saitoh A, Kondoh E, Fujimoto H, et al. Clinical effi cacy of macrolide antibiotics against genetically determined macrolide-resistant Mycoplasma pneumoniae pneumonia in paediatric patients. Respirology 2012; 17: 354-62.
24. Akaike H, Miyashita N, Kubo M, Kawai Y, Tanaka T, Ogita S, et al. In vitro activities of 11 antimicrobial agents against macrolide-resistant Mycoplasma pneumoniae isolates from pediatric patients: results from a multicenter surveillance study. Jpn J Infect Dis 2012; 65: 535-8.