The involvement of CXCL11 in bone marrow-derived mesenchymal stem cell migration through human brain microvascular endothelial cells

Neurochemical Research

Volumn 39, Issue 4, 2014, Pages 700-706

  Feng, Yu ^a   Yu, Hong Mei ^a   Shang, De Shu ^a   Fang, Wen Gang ^a   He, Zhi Yi ^a   Chen, Yu Hua ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Blood brain barrier; Bone marrow derived mesenchymal stem cell; Brain microvascular endothelial cell; Chemokine CXCL11; CXCR3; Tight junction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CHEMOKINE RECEPTOR CXCR3; CXCL11 CHEMOKINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; NEUTRALIZING ANTIBODY; OCCLUDIN; CXCL11 PROTEIN, HUMAN; CXCR3 PROTEIN, HUMAN; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; CELL FRACTIONATION; CELL INTERACTION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MALE; MESENCHYMAL STEM CELL; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SOLUBILITY; SUPERNATANT; TIGHT JUNCTION; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; WESTERN BLOTTING; ANIMAL; BONE MARROW; CELL CULTURE; CELL MOTION; ENDOTHELIUM CELL; MESENCHYMAL STROMA CELL; METABOLISM; MICROVASCULATURE; PHYSIOLOGY; SECRETION (PROCESS); WISTAR RAT;

ANIMALS; BLOOD-BRAIN BARRIER; BONE MARROW; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CXCL11; ENDOTHELIAL CELLS; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; MICROVESSELS; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, CXCR3;

EID: 84898895435     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1257-7     Document Type: Article

References (27)

1. Dezawa M, Ishikawa H, Itokazu Y, Yoshihara T, Hoshino M, Takeda S, Ide C, Nabeshima Y (2005) Bone marrow stromal cells generate muscle cells and repair muscle degeneration. Science 309:314-317
2. McFarlin K, Gao X, Liu YB, Dulchavsky DS, Kwon D, Arbab AS, Bansal M, Li Y, Chopp M, Dulchavsky SA, Gautam SC (2006) Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat. Wound Repair Regen 14:471-478
3. Rüster B, Göttig S, Ludwig RJ, Bistrian R, Müller S, Seifried E, Gille J, Henschler R (2006) Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells. Blood 108:3938-3944
4. Sordi V, Malosio ML, Marchesi F, Mercalli A, Melzi R, Giordano T, Belmonte N, Ferrari G, Leone BE, Bertuzzi F, Zerbini G, Allavena P, Bonifacio E, Piemonti L (2005) Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood 106:419-427
5. Son BR, Marquez-Curtis LA, Kucia M, Wysoczynski M, Turner AR, Ratajczak J, Ratajczak MZ, Janowska-Wieczorek A (2006) Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-Met axes and involves matrix metalloproteinases. Stem Cells 24:1254-1264
6. Lee JK, Jin HK, Endo S, Schuchman EH, Carter JE, Bae JS (2010) Intracerebral transplantation of bone marrowderived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease mice by modulation of immune responses. Stem Cells 28:329-343
7. Danielyan L, Schäfer R, von Ameln-Mayerhofer A, Buadze M, Geisler J, Klopfer T, Burkhardt U, Proksch B, Verleysdonk S, Ayturan M, Buniatian GH, Gleiter CH, Frey WH 2nd (2009) Intranasal delivery of cells to the brain. Eur J Cell Biol 88:315-324
8. Dharmasaroja P (2009) Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke. J Clin Neurosci 16:12-20
9. Abbott NJ, Patabendige AA, Dolman DE, Yusof SR, Begley DJ (2009) Structure and function of the blood-brain barrier. Neurobiol Dis 37:13-25
10. Liu WY, Wang ZB, Zhang LC, Wei X, Li L (2012) Tight junction in blood-brain barrier: an overview of structure, regulation, and regulator substances. CNS Neurosci Ther 18:609-615
11. Zhou SB, Wang J, Chiang CA, Sheng LL, Li QF (2013) Mechanical stretch upregulates Sdf-1α in skin tissue and induces migration of circulating bone marrow-derived stem cells into the expanded skin. Stem Cells. doi: 10.1002/stem.1479
12. Augello A, Kurth TB, De Bari C (2010) Mesenchymal stem cells: a perspective from in vitro cultures to in vivo migration and niches. Eur Cell Mate 20:121-133
13. Chamberlain G, Smith H, Rainger GE, Middleton J (2011) Mesenchymal stem cells exhibit firm adhesion, crawling, spreading and transmigration across aortic endothelial cells: effects of chemokines and shear. PLoS ONE 6:e25663
14. Carrero R, Cerrada I, Lledó E, Dopazo J, García- García F, Rubio MP, Trigueros C, Dorronsoro A, Ruiz-Sauri A, Montero JA, Sepúlveda P (2012) IL1β induces mesenchymal stem cells migration and leucocyte chemotaxis through NF-κB. Stem Cell Rev 8:905-916
15. Trotta T, Costantini S, Colonna G (2009) Modelling of the membrane receptor CXCR3 and its complexes with CXCL9, CXCL10 and CXCL11 chemokines: putative target for new drug design. Mol Immunol 47:332-339
16. Sung HJ, Hong SC, Yoo JH, Oh JH, Shin HJ, Choi IY, Ahn KH, Kim SH, Park Y, Kim BS (2010) Stemness evaluation of mesenchymal stem cells from placentas according to developmental stage: comparison to those from adult bone marrow. J Korean Med Sci 25:1418-1426
17. Tropel P, Noël D, Platet N, Legrand P, Benabid AL, Berger F (2004) Isolation and characterisation of mesenchymal stem cells from adult mouse bone marrow. Exp Cell Res 295:395-406
18. Lin MN, Shang DS, Sun W, Li B, Xu X, Fang WG, Zhao WD, Cao L, Chen YH (2013) Involvement of PI3K and ROCK signaling pathways in migration of bone marrow-derived mesenchymal stem cells through human brain microvascular endothelial cell monolayers. Brain Res 1513:1-8
19. Greco SJ, Rameshwar P (2008) Microenvironmental considerations in the application of human mesenchymal stem cells in regenerative therapies. Biologics 2:699-705
20. Wolf MJ, Hoos A, Bauer J, Boettcher S, Knust M, Weber A, Simonavicius N, Schneider C, Lang M, Stürzl M, Croner RS, Konrad A, Manz MG, Moch H, Aguzzi A, van Loo G, Pasparakis M, Prinz M, Borsig L, Heikenwalder M (2012) Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway. Cancer Cell 22:91-105
21. Man SM, Ma YR, Shang DS, Zhao WD, Li B, Guo DW, Fang WG, Zhu L, Chen YH (2007) Peripheral T cells overexpress MIP-1 α to enhance its transendothelial migration in Alzheimer's disease. Neurobiol Aging 28:485-496
22. Lazzeri E, Romagnani P (2005) CXCR3-binding chemokines: novel multifunctional therapeutic targets. Curr Drug Targets Immune Endocr Metabol Disord 5:109-118
23. Zeremski M, Petrovic LM, Talal AH (2007) The role of chemokines as inflammatory mediators in chronic hepatitis C virus infection. J Viral Hepat 14:675-687
24. Groom JR, Luster AD (2011) CXCR3 in T cell function. Exp Cell Res 317:620-631
25. Groom JR, Luster AD (2011) CXCR3 ligands: redundant, collaborative and antagonistic functions. Immunol Cell Biol 89:207-215
26. Müller M, Carter S, Hofer MJ, Campbell IL (2010) Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity - a tale of conflict and conundrum. Neuropathol Appl Neurobiol 36:368-387
27. Loetscher P, Clark-Lewis I (2001) Agonistic and antagonistic activities of chemokines. J Leukoc Biol 69:881-884