-
1
-
-
69449085928
-
The changing epidemiology of lung cancer with a focus on screening
-
Silvestri GA, Alberg AJ,Ravenel J. The changing epidemiology of lung cancer with a focus on screening. BMJ 2009;339:b3053.
-
(2009)
BMJ
, vol.339
-
-
Silvestri, G.A.1
Alberg, A.J.2
Ravenel, J.3
-
2
-
-
57349095906
-
The international epidemiology of lung cancer; geographical distribution and secular trends
-
Youlden DR, Cramb SM, Baade PD. The international epidemiology of lung cancer; geographical distribution and secular trends. J Thorac Oncol 2008;3:819831.
-
(2008)
J Thorac Oncol
, vol.3
, pp. 819831
-
-
Youlden, D.R.1
Cramb, S.M.2
Baade, P.D.3
-
3
-
-
0028009789
-
Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair
-
Chu G. Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair. J Biol Chem 1994;269:787-790.
-
(1994)
J Biol Chem
, vol.269
, pp. 787-790
-
-
Chu, G.1
-
4
-
-
15044359729
-
New therapeutic approaches for early stage non-small cell lung cancer
-
DOI 10.1016/j.suronc.2004.11.002
-
El-Sherif A, Luketich JD, Landreneau RJ, Fernando HC. New therapeutic approaches for early stage nonsmall cell lung cancer. Surg Oncol 2005;14:27-32. (Pubitemid 40380620)
-
(2005)
Surgical Oncology
, vol.14
, Issue.1
, pp. 27-32
-
-
El-Sherif, A.1
Luketich, J.D.2
Landreneau, R.J.3
Fernando, H.C.4
-
5
-
-
0026719114
-
Modulation of cis-diamminedichloroplatinum(II) resistance: A review
-
Timmer-Bosscha H, Mulder NH,de Vries EG. Modulation of cis-diamminedichloroplatinum(II) resistance: a review. Br J Cancer 1992;66:227-238.
-
(1992)
Br J Cancer
, vol.66
, pp. 227-238
-
-
Timmer-Bosscha, H.1
Mulder, N.H.2
De Vries, E.G.3
-
6
-
-
0028879760
-
Cisplatin and DNA repair in cancer chemotherapy
-
Zambie DB, Lippard SJ. Cisplatin and DNA repair in cancer chemotherapy. Trends Biochem Sci 1995;20:435-439.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 435-439
-
-
Zambie, D.B.1
Lippard, S.J.2
-
7
-
-
0030840464
-
STATs and gene regulation
-
Darnell JE Jr. STATs and gene regulation. Science 1997;277:1630-1635.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell Jr., J.E.1
-
8
-
-
1042302005
-
The stats of cancer - New molecular targets come of age
-
Yu H, Jove R. The STATs of cancer-new molecular targets come of age. Nat Rev Cancer 2004;4:97-105. (Pubitemid 38198738)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.2
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
9
-
-
0033529704
-
Stat3 as an oncogene
-
DOI 10.1016/S0092-8674(00)81959-5
-
Bromberg JF, Wrzeszczynska MH, Devgan G et al. Stat3 as an oncogene. Cell 1999;98:295-303. (Pubitemid 29380565)
-
(1999)
Cell
, vol.98
, Issue.3
, pp. 295-303
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.5
Albanese, C.6
Darnell Jr., J.E.7
-
10
-
-
12944272024
-
Constitutive activation of stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo
-
DOI 10.1073/pnas.97.8.4227
-
Grandis JR, Drenning SD, Zeng Q et al. Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proc Natl Acad Sci U S A 2000;97:4227-4232. (Pubitemid 30226115)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.8
, pp. 4227-4232
-
-
Grandis, J.R.1
Drenning, S.D.2
Zeng, Q.3
Watkins, S.C.4
Melhem, M.F.5
Endo, S.6
Johnson, D.E.7
Huang, L.8
He, Y.9
Kim, J.D.10
-
11
-
-
84863076111
-
Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters
-
He Y, Zhou Z, Hofstetter WL et al. Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters. PLoS One 2012;7:e31087.
-
(2012)
PLoS One
, vol.7
-
-
He, Y.1
Zhou, Z.2
Hofstetter, W.L.3
-
12
-
-
0034618521
-
Structure and functional analysis of the human STAT3 gene promoter: Alteration of chromatin structure as a possible mechanism for the upregulation in cisplatin-resistant cells
-
Kato K, Nomoto M, Izumi H et al. Structure and functional analysis of the human STAT3 gene promoter: alteration of chromatin structure as a possible mechanism for the upregulation in cisplatin-resistant cells. Biochim Biophys Acta 2000;1493:91-100.
-
(2000)
Biochim Biophys Acta
, vol.1493
, pp. 91-100
-
-
Kato, K.1
Nomoto, M.2
Izumi, H.3
-
13
-
-
16244412004
-
Overexpression of constitutive signal transducer and activator of transcription 3 mRNA in cisplatin-resistant human nonsmall cell lung cancer cells
-
Ikuta K, Takemura K, Kihara M et al. Overexpression of constitutive signal transducer and activator of transcription 3 mRNA in cisplatin-resistant human nonsmall cell lung cancer cells. Oncol Rep 2005;13:217-222.
-
(2005)
Oncol Rep
, vol.13
, pp. 217-222
-
-
Ikuta, K.1
Takemura, K.2
Kihara, M.3
-
14
-
-
33746556993
-
A brief history of RNAi: The silence of the genes
-
DOI 10.1096/fj.06-6014rev
-
Sen GL, Blau HM. A brief history of RNAi: the silence of the genes. FASEB J 2006;20:1293-1299. (Pubitemid 44943837)
-
(2006)
FASEB Journal
, vol.20
, Issue.9
, pp. 1293-1299
-
-
Sen, G.L.1
Blau, H.M.2
-
16
-
-
0041331496
-
SiRNA function in RNAi: A chemical modification analysis
-
DOI 10.1261/rna.5103703
-
Chiu YL, Rana TM. siRNA function in RNAi: a chemical modification analysis. RNA 2003;9:1034-1048. (Pubitemid 37093614)
-
(2003)
RNA
, vol.9
, Issue.9
, pp. 1034-1048
-
-
Chiu, Y.-L.1
Rana, T.M.2
-
17
-
-
84878111348
-
Gene silencing by chemically modified siRNAs
-
Engels JW. Gene silencing by chemically modified siRNAs. N Biotechnol 2013;30:302-307.
-
(2013)
N Biotechnol
, vol.30
, pp. 302-307
-
-
Engels, J.W.1
-
18
-
-
84872320115
-
Repression of STAT3, STAT5A, and STAT5B expressions in chronic myelogenous leukemia cell line K-562 with unmodifled or chemically modified siRNAs and induction of apoptosis
-
Kaymaz BT, Selvi N, Gunduz C et al. Repression of STAT3, STAT5A, and STAT5B expressions in chronic myelogenous leukemia cell line K-562 with unmodifled or chemically modified siRNAs and induction of apoptosis. Ann Hematol 2012;92:151-162.
-
(2012)
Ann Hematol
, vol.92
, pp. 151-162
-
-
Kaymaz, B.T.1
Selvi, N.2
Gunduz, C.3
-
19
-
-
84859226721
-
Cispla- tin resistance induced by decreased apoptotic activity in non-small-cell lung cancer cell lines
-
Cetintas VB, Kucukaslan AS, Kosova B et al. Cispla- tin resistance induced by decreased apoptotic activity in non-small-cell lung cancer cell lines. Cell Biol Int 2012;36:261-265.
-
(2012)
Cell Biol Int
, vol.36
, pp. 261-265
-
-
Cetintas, V.B.1
Kucukaslan, A.S.2
Kosova, B.3
-
20
-
-
77957723878
-
Suppression of STAT5A increases chemotherapeutic sensitivity in imatinib-resistant and imatinib-sensitive K562 cells
-
Kosova B, Tezcanli B, Ekiz HA et al. Suppression of STAT5A increases chemotherapeutic sensitivity in imatinib-resistant and imatinib-sensitive K562 cells. Leuk Lymphoma 2010;51:1895-1901.
-
(2010)
Leuk Lymphoma
, vol.51
, pp. 1895-1901
-
-
Kosova, B.1
Tezcanli, B.2
Ekiz, H.A.3
-
21
-
-
0042349236
-
Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements
-
DOI 10.1016/S1535-6108(03)00169-7
-
Primiano T, Baig M, Maliyekkel A et al. Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements. Cancer Cell 2003;4:41-53. (Pubitemid 36904160)
-
(2003)
Cancer Cell
, vol.4
, Issue.1
, pp. 41-53
-
-
Primiano, T.1
Baig, M.2
Maliyekkel, A.3
Chang, B.-D.4
Fellars, S.5
Sadhu, J.6
Axenovich, S.A.7
Holzmayer, T.A.8
Roninson, I.B.9
-
22
-
-
33751575658
-
The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis
-
DOI 10.1002/cncr.22293
-
Rosen DG, Mercado-Uribe I, Yang G et al. The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis. Cancer 2006;107:2730-2740. (Pubitemid 44845630)
-
(2006)
Cancer
, vol.107
, Issue.11
, pp. 2730-2740
-
-
Rosen, D.G.1
Mercado-Uribe, I.2
Yang, G.3
Bast Jr., R.C.4
Amin, H.M.5
Lai, R.6
Liu, J.7
-
23
-
-
84856453840
-
Prognostic significance of STAT3 expression and its correlation with chemoresistance of non-small cell lung cancer cells
-
Yin Z, Zhang Y, Li Y et al. Prognostic significance of STAT3 expression and its correlation with chemoresistance of non-small cell lung cancer cells. Acta Histochem 2012;114:151-158.
-
(2012)
Acta Histochem
, vol.114
, pp. 151-158
-
-
Yin, Z.1
Zhang, Y.2
Li, Y.3
-
24
-
-
84870310032
-
PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells
-
Su WP, Cheng FY, Shieh DB et al. PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells. Int J Nanomedicine 2012;7:4269-4283.
-
(2012)
Int J Nanomedicine
, vol.7
, pp. 4269-4283
-
-
Su, W.P.1
Cheng, F.Y.2
Shieh, D.B.3
-
25
-
-
84875490171
-
Silencing of the transcription factor STAT3 sensitizes lung cancer cells to DNA damaging drugs, but not to TNFalpha- and NK cytotoxicity
-
Kulesza DW, Carre T, Chouaib S, Kaminska B. Silencing of the transcription factor STAT3 sensitizes lung cancer cells to DNA damaging drugs, but not to TNFalpha- and NK cytotoxicity. Exp Cell Res 2013;319:506-516.
-
(2013)
Exp Cell Res
, vol.319
, pp. 506-516
-
-
Kulesza, D.W.1
Carre, T.2
Chouaib, S.3
Kaminska, B.4
-
26
-
-
84355161519
-
Inhibition of activated Stat3 reverses drug resistance to chemotherapeutic agents in gastric cancer cells
-
Huang S, Chen M, Shen Y et al. Inhibition of activated Stat3 reverses drug resistance to chemotherapeutic agents in gastric cancer cells. Cancer Lett 2012;315:198-205.
-
(2012)
Cancer Lett
, vol.315
, pp. 198-205
-
-
Huang, S.1
Chen, M.2
Shen, Y.3
-
27
-
-
3943103442
-
RNA interference targeting Stat3 inhibits growth and induces apoptosis of human prostate cancer cells
-
Lee SO, Lou W, Qureshi KM et al. RNA interference targeting Stat3 inhibits growth and induces apoptosis of human prostate cancer cells. Prostate 2004;60:303309.
-
(2004)
Prostate
, vol.60
, pp. 303309
-
-
Lee, S.O.1
Lou, W.2
Qureshi, K.M.3
-
28
-
-
84859937791
-
Caveolin-1 silencing arrests the proliferation of metastatic lung cancer cells through the inhibition of STAT3 signaling
-
Pancotti F, Roncuzzi L, Maggiolini M, Gasperi-Campani A. Caveolin-1 silencing arrests the proliferation of metastatic lung cancer cells through the inhibition of STAT3 signaling. Cell Signal 2012;24:1390-1397.
-
(2012)
Cell Signal
, vol.24
, pp. 1390-1397
-
-
Pancotti, F.1
Roncuzzi, L.2
Maggiolini, M.3
Gasperi-Campani, A.4
-
29
-
-
77953807862
-
Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin
-
Liu T, Peng H, Zhang M et al. Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin. Eur J Pharmacol 2010;641:15-22.
-
(2010)
Eur J Pharmacol
, vol.641
, pp. 15-22
-
-
Liu, T.1
Peng, H.2
Zhang, M.3
-
30
-
-
81155131866
-
Overexpression of STAT3 potentiates growth, survival, and radioresistance of non-small-cell lung cancer (NSCLC) cells
-
Yin ZJ, Jin FG, Liu TG et al. Overexpression of STAT3 potentiates growth, survival, and radioresistance of non-small-cell lung cancer (NSCLC) cells. J Surg Res 2011;171:675-683.
-
(2011)
J Surg Res
, vol.171
, pp. 675-683
-
-
Yin, Z.J.1
Jin, F.G.2
Liu, T.G.3
-
31
-
-
62149128292
-
Effects of STAT3 antisense oligonucleotide on proliferation and apoptosis of non-small cell lung cancer cell line A549
-
Zhu BR, Cai JM, Tang GS et al. Effects of STAT3 antisense oligonucleotide on proliferation and apoptosis of non-small cell lung cancer cell line A549. Ai Zheng 2007;26:820-827.
-
(2007)
Ai Zheng
, vol.26
, pp. 820-827
-
-
Zhu, B.R.1
Cai, J.M.2
Tang, G.S.3
-
32
-
-
84898869728
-
Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice
-
Zhang X, Zhang J, Wang L et al. Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice. BMC Cancer 2007;149:1-11.
-
(2007)
BMC Cancer
, vol.149
, pp. 1-11
-
-
Zhang, X.1
Zhang, J.2
Wang, L.3
-
33
-
-
33845865865
-
The STAT3 oncogene as a predictive marker of drug resistance
-
Barre B, Vigneron A, Perkins N et al. The STAT3 oncogene as a predictive marker of drug resistance. Trends Mol Med 2007;13:4-11.
-
(2007)
Trends Mol Med
, vol.13
, pp. 4-11
-
-
Barre, B.1
Vigneron, A.2
Perkins, N.3
-
34
-
-
0034700154
-
Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin
-
O'Connor DS, Grossman D, Plescia J et al. Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc Natl Acad Sci U S A 2000;97:13103-13107.
-
(2000)
Proc Natl Acad Sci U S a
, vol.97
, pp. 13103-13107
-
-
O'Connor, D.S.1
Grossman, D.2
Plescia, J.3
-
35
-
-
77955520465
-
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells
-
Aug 16
-
Lin L, Deangelis S, Foust E et al. A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells. Mol Cancer 2010 Aug 16;9:217.
-
(2010)
Mol Cancer
, vol.9
, pp. 217
-
-
Lin, L.1
Deangelis, S.2
Foust, E.3
-
36
-
-
84898864702
-
Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma
-
Ma J, Wang S, Zhao M et al. Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma. BMC Cancer 2011;255:111.
-
(2011)
BMC Cancer
, vol.255
, pp. 111
-
-
Ma, J.1
Wang, S.2
Zhao, M.3
-
37
-
-
84861345772
-
Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells
-
Yue P, Zhang X, Paladino D et al. Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells. Oncogene 2012;31:2309-2322.
-
(2012)
Oncogene
, vol.31
, pp. 2309-2322
-
-
Yue, P.1
Zhang, X.2
Paladino, D.3
-
38
-
-
33645506849
-
Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor
-
Alvarez JV, Greulich H, Sellers WR et al. Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor. Cancer Res 2006;66:3162-3168.
-
(2006)
Cancer Res
, vol.66
, pp. 3162-3168
-
-
Alvarez, J.V.1
Greulich, H.2
Sellers, W.R.3
|