-
1
-
-
0026573783
-
Adaptation of islets of Langerhans to pregnancy: Increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion
-
Parsons J, Brelje T, Sorenson R (1992) Adaptation of islets of Langerhans to pregnancy: increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion. Endocrinology 130: 1459-1466.
-
(1992)
Endocrinology
, vol.130
, pp. 1459-1466
-
-
Parsons, J.1
Brelje, T.2
Sorenson, R.3
-
2
-
-
0030825432
-
Adaptation of islets of Langerhans to pregnancy: beta-cell growth, enhanced insulin secretion and the role of lactogenic hormones
-
Sorenson RL, Brelje TC (1997) Adaptation of islets of Langerhans to pregnancy: beta-cell growth, enhanced insulin secretion and the role of lactogenic hormones. Horm Metab Res 29: 301-307. (Pubitemid 27293660)
-
(1997)
Hormone and Metabolic Research
, vol.29
, Issue.6
, pp. 301-307
-
-
Sorenson, R.L.1
Brelje, T.C.2
-
3
-
-
63849322132
-
Prolactin receptor is required for normal glucose homeostasis and modulation of beta-cell mass during pregnancy
-
Huang C, Snider F, Cross JC (2009) Prolactin receptor is required for normal glucose homeostasis and modulation of beta-cell mass during pregnancy. Endocrinology 150: 1618-1626.
-
(2009)
Endocrinology
, vol.150
, pp. 1618-1626
-
-
Huang, C.1
Snider, F.2
Cross, J.C.3
-
4
-
-
0036179723
-
An immunohistochemical approach to monitor the prolactin-induced activation of the JAK2/STAT5 pathway in pancreatic islets of langerhans
-
Brelje TC, Svensson AM, Stout LE, Bhagroo NV, Sorenson RL (2002) An immunohistochemical approach to monitor the prolactin-induced activation of the JAK2/STAT5 pathway in pancreatic islets of Langerhans. J Histochem Cytochem 50: 365-383. (Pubitemid 34171060)
-
(2002)
Journal of Histochemistry and Cytochemistry
, vol.50
, Issue.3
, pp. 365-383
-
-
Brelje, T.C.1
Svensson, A.M.2
Stout, L.E.3
Bhagroo, N.V.4
Sorenson, R.L.5
-
5
-
-
0041426728
-
Prolactin-signal transduction in neonatal rat pancreatic islets and interaction with the insulin-signaling pathway
-
DOI 10.1055/s-2003-41303
-
Amaral MEC, Ueno M, Carvalheira JB, Carneiro EM, Velloso LA, et al. (2003) Prolactin-signal transduction in neonatal rat pancreatic islets and interaction with the insulin-signaling pathway. Horm Metab Res 35: 282-289. (Pubitemid 37011513)
-
(2003)
Hormone and Metabolic Research
, vol.35
, Issue.5
, pp. 282-289
-
-
Amaral, M.E.C.1
Ueno, M.2
Carvalheira, J.B.3
Carneiro, E.M.4
Velloso, L.A.5
Saad, M.J.A.6
Boschero, A.C.7
-
6
-
-
70349774453
-
The transcriptional response of the islet to pregnancy in mice
-
Rieck S, White P, Schug J, Fox AJ, Smirnova O, et al. (2009) The transcriptional response of the islet to pregnancy in mice. Mol Endocrinol 23: 1702-1712.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1702-1712
-
-
Rieck, S.1
White, P.2
Schug, J.3
Fox, A.J.4
Smirnova, O.5
-
7
-
-
78649329990
-
Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy
-
Schraenen A, Lemaire K, Faudeur G, Hendrickx N, Granvik M, et al. (2010) Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy. Diabetologia 53: 2589-2599.
-
(2010)
Diabetologia
, vol.53
, pp. 2589-2599
-
-
Schraenen, A.1
Lemaire, K.2
Faudeur, G.3
Hendrickx, N.4
Granvik, M.5
-
8
-
-
78649334977
-
mRNA expression analysis of cell cycle genes in islets of pregnant mice
-
Schraenen A, de Faudeur G, Thorrez L, Lemaire K, Van Wichelen G, et al. (2010) mRNA expression analysis of cell cycle genes in islets of pregnant mice. Diabetologia 53: 2579-2588.
-
(2010)
Diabetologia
, vol.53
, pp. 2579-2588
-
-
Schraenen, A.1
De Faudeur, G.2
Thorrez, L.3
Lemaire, K.4
Van Wichelen, G.5
-
9
-
-
77954480533
-
Serotonin regulates pancreatic beta cell mass during pregnancy
-
Kim H, Toyofuku Y, Lynn FC, Chak E, Uchida T, et al. (2010) Serotonin regulates pancreatic beta cell mass during pregnancy. Nature Medicine 16: 804-808.
-
(2010)
Nature Medicine
, vol.16
, pp. 804-808
-
-
Kim, H.1
Toyofuku, Y.2
Lynn, F.C.3
Chak, E.4
Uchida, T.5
-
10
-
-
77449086017
-
Gestational diabetes mellitus resulting from impaired beta-cell compensation in the absence of FoxM1, a novel downstream effector of placental lactogen
-
Zhang H, Zhang J, Pope CF, Crawford LA, Vasavada RC, et al. (2010) Gestational diabetes mellitus resulting from impaired beta-cell compensation in the absence of FoxM1, a novel downstream effector of placental lactogen. Diabetes 59: 143-152.
-
(2010)
Diabetes
, vol.59
, pp. 143-152
-
-
Zhang, H.1
Zhang, J.2
Pope, C.F.3
Crawford, L.A.4
Vasavada, R.C.5
-
11
-
-
38449099624
-
Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus
-
DOI 10.1126/science.1146812
-
Karnik SK, Chen H, McLean GW, Heit JJ, Gu X, et al. (2007) Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus. Science 318: 806-809. (Pubitemid 351411773)
-
(2007)
Science
, vol.318
, Issue.5851
, pp. 806-809
-
-
Karnik, S.K.1
Chen, H.2
McLean, G.W.3
Heit, J.J.4
Gu, X.5
Zhang, A.Y.6
Fontaine, M.7
Yen, M.H.8
Kim, S.K.9
-
12
-
-
79959726397
-
Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation
-
Hakonen E, Ustinov J, Mathijs I, Palgi J, Bouwens L, et al. (2011) Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation. Diabetologia 54: 1735-1743.
-
(2011)
Diabetologia
, vol.54
, pp. 1735-1743
-
-
Hakonen, E.1
Ustinov, J.2
Mathijs, I.3
Palgi, J.4
Bouwens, L.5
-
13
-
-
77949324263
-
Expansion of beta-cell mass in response to pregnancy
-
Rieck S, Kaestner KH (2010) Expansion of beta-cell mass in response to pregnancy. Trends Endocrinol Metab 21: 151-158.
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 151-158
-
-
Rieck, S.1
Kaestner, K.H.2
-
14
-
-
0028985830
-
Number and size of islets of Langerhans in pregnant, human growth hormone-expressing transgenic, and pituitary dwarf mice: Effect of lactogenic hormones
-
Parsons J, Bartke A, Sorenson R (1995) Number and size of islets of Langerhans in pregnant, human growth hormone-expressing transgenic, and pituitary dwarf mice: effect of lactogenic hormones. Endocrinology 136: 2013-2021.
-
(1995)
Endocrinology
, vol.136
, pp. 2013-2021
-
-
Parsons, J.1
Bartke, A.2
Sorenson, R.3
-
15
-
-
77953511021
-
Non-β-cell progenitors of b-cells in pregnant mice
-
Abouna S, Old RW, Pelengaris S, Epstein D, Ifandi V, et al. (2010) Non-β-cell progenitors of b-cells in pregnant mice. Organogenesis 6: 125-133.
-
(2010)
Organogenesis
, vol.6
, pp. 125-133
-
-
Abouna, S.1
Old, R.W.2
Pelengaris, S.3
Epstein, D.4
Ifandi, V.5
-
16
-
-
77958040076
-
Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy
-
Butler AE, Cao-Minh L, Galasso R, Rizza RA, Corradin A, et al. (2010) Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy. Diabetologia 53: 2167-2176.
-
(2010)
Diabetologia
, vol.53
, pp. 2167-2176
-
-
Butler, A.E.1
Cao-Minh, L.2
Galasso, R.3
Rizza, R.A.4
Corradin, A.5
-
17
-
-
33845926261
-
Tomographic molecular imaging and 3D quantification within adult mouse organs
-
DOI 10.1038/nmeth985, PII NMETH985
-
Alanentalo T, Asayesh A, Morrison H, Lorén CE, Holmberg D, et al. (2006) Tomographic molecular imaging and 3D quantification within adult mouse organs. Nat Methods 4: 31-33. (Pubitemid 46029471)
-
(2007)
Nature Methods
, vol.4
, Issue.1
, pp. 31-33
-
-
Alanentalo, T.1
Asayesh, A.2
Morrison, H.3
Loren, C.E.4
Holmberg, D.5
Sharpe, J.6
Ahlgren, U.7
-
18
-
-
77954298756
-
Quantification and three-dimensional imaging of the insulitis-induced destruction of beta-cells in murine type 1 diabetes
-
Alanentalo T, Hörnblad A, Mayans S, Karin Nilsson A, Sharpe J, et al. (2010) Quantification and three-dimensional imaging of the insulitis-induced destruction of beta-cells in murine type 1 diabetes. Diabetes 59: 1756-1764.
-
(2010)
Diabetes
, vol.59
, pp. 1756-1764
-
-
Alanentalo, T.1
Hörnblad, A.2
Mayans, S.3
Karin Nilsson, A.4
Sharpe, J.5
-
19
-
-
33845534764
-
Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth
-
DOI 10.2337/db06-0413
-
Miettinen PJ, Ustinov J, Ormio P, Gao R, Palgi J, et al. (2006) Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth. Diabetes 55: 3299-3308. (Pubitemid 44923586)
-
(2006)
Diabetes
, vol.55
, Issue.12
, pp. 3299-3308
-
-
Miettinen, P.J.1
Ustinov, J.2
Ormio, P.3
Gao, R.4
Palgi, J.5
Hakonen, E.6
Juntti-Berggren, L.7
Berggren, P.-O.8
Otonkoski, T.9
-
20
-
-
84898602169
-
In vivo activation of the PI3K-Akt pathway in mouse beta cells by the EGFR mutation L858R protects against diabetes
-
doi:10.1007/s00125-014-3175-2
-
Hakonen E, Ustinov J, Eizirik DL, Sariola H, Miettinen PJ, et al. (2014) In vivo activation of the PI3K-Akt pathway in mouse beta cells by the EGFR mutation L858R protects against diabetes. Diabetologia. doi:10.1007/s00125-014- 3175-2.
-
(2014)
Diabetologia
-
-
Hakonen, E.1
Ustinov, J.2
Eizirik, D.L.3
Sariola, H.4
Miettinen, P.J.5
-
21
-
-
0035710746
-
-Delta DeltaCT method
-
DOI 10.1006/meth.2001.1262
-
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408. (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
22
-
-
33748742635
-
Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression
-
DOI 10.1074/jbc.M603414200
-
Peng X-H, Karna P, Cao Z, Jiang B-H, Zhou M, et al. (2006) Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression. J Biol Chem 281: 25903-25914. (Pubitemid 44401796)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.36
, pp. 25903-25914
-
-
Peng, X.-H.1
Karna, P.2
Cao, Z.3
Jiang, B.-H.4
Zhou, M.5
Yang, L.6
-
23
-
-
0036827577
-
ErbB signaling regulates lineage determination of developing pancreatic islet cells in embryonic organ culture
-
DOI 10.1210/en.2002-220382
-
Huotari M-A, Miettinen PJ, Palgi J, Koivisto T, Ustinov J, et al. (2002) ErbB signaling regulates lineage determination of developing pancreatic islet cells in embryonic organ culture. Endocrinology 143: 4437-4446. (Pubitemid 35239578)
-
(2002)
Endocrinology
, vol.143
, Issue.11
, pp. 4437-4446
-
-
Huotari, M.-A.1
Miettinen, P.J.2
Palgi, J.3
Koivisto, T.4
Ustinov, J.5
Harari, D.6
Yarden, Y.7
Otonkoski, T.8
-
24
-
-
0030829784
-
Systemic treatment with epidermal growth factor in pigs induces ductal proliferations in the pancreas
-
DOI 10.1053/gast.1997.v113.pm9322532
-
Vinter-Jensen L, Juhl C, Teglbjaerg P, Poulsen S, Dajani E, et al. (1997) Systemic treatment with epidermal growth factor in pigs induces ductal proliferations in the pancreas. Gastroenterology 113: 1367-1374. (Pubitemid 27418991)
-
(1997)
Gastroenterology
, vol.113
, Issue.4
, pp. 1367-1374
-
-
Vinter-Jensen, L.1
Juhl, C.O.2
Teglbjaerg, P.S.3
Poulsen, S.S.4
Dajani, E.Z.5
Nexo, E.6
-
25
-
-
0037382091
-
Overexpression of Heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia
-
DOI 10.1053/gast.2003.50150
-
Means AL, Ray KC, Singh AB, Washington MK, Whitehead RH, et al. (2003) Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia. Gastroenterology 124: 1020-1036. (Pubitemid 36389805)
-
(2003)
Gastroenterology
, vol.124
, Issue.4
, pp. 1020-1036
-
-
Means, A.L.1
Ray, K.C.2
Singh, A.B.3
Washington, M.K.4
Whitehead, R.H.5
Harris Jr., R.C.6
Wright, C.V.E.7
Coffey Jr., R.J.8
Leach, S.D.9
-
26
-
-
0035406148
-
Epidermal Growth Factor Increases Undifferentiated Pancreatic Embryonic Cells in Vitro: A Balance between Proliferation and Differentiation
-
Cras-Meneur C, Elghazi L, Czernichow P, Scharfmann R (2001) Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation. Diabetes 50: 1571-1579. (Pubitemid 33639597)
-
(2001)
Diabetes
, vol.50
, Issue.7
, pp. 1571-1579
-
-
Cras-Meneur, C.1
Elghazi, L.2
Czernichow, P.3
Scharfmann, R.4
-
27
-
-
0030044360
-
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
-
DOI 10.1038/379557a0
-
Daub H, Weiss FU, Wallasch C, Ullrich A (1996) Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 379: 557-560. (Pubitemid 26049585)
-
(1996)
Nature
, vol.379
, Issue.6565
, pp. 557-560
-
-
Daub, H.1
Weiss, F.U.2
Wallasch, C.3
Ullrich, A.4
-
28
-
-
1342323632
-
ErbB Receptors: Directing Key Signaling Networks Throughout Life
-
DOI 10.1146/annurev.pharmtox.44.101802.121440
-
Holbro T, Hynes NE (2004) ErbB receptors: directing key signaling networks throughout life. Annu Rev Pharmacol Toxicol 44: 195-217. (Pubitemid 38263839)
-
(2004)
Annual Review of Pharmacology and Toxicology
, vol.44
, pp. 195-217
-
-
Holbro, T.1
Hynes, N.E.2
-
29
-
-
33845528355
-
Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells
-
DOI 10.1038/sj.onc.1209740, PII 1209740
-
Huang Y, Li X, Jiang J, Frank SJ (2006) Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells. Oncogene 25: 7565-7576. (Pubitemid 44924470)
-
(2006)
Oncogene
, vol.25
, Issue.58
, pp. 7565-7576
-
-
Huang, Y.1
Li, X.2
Jiang, J.3
Frank, S.J.4
-
30
-
-
40249094410
-
Mechanistic aspects of crosstalk between GH and PRL and ErbB receptor family signaling
-
Frank SJ (2008) Mechanistic aspects of crosstalk between GH and PRL and ErbB receptor family signaling. J Mammary Gland Biol Neoplasia 13: 119-129.
-
(2008)
J Mammary Gland Biol Neoplasia
, vol.13
, pp. 119-129
-
-
Frank, S.J.1
-
31
-
-
0032403126
-
IAP-family protein Survivin inhibits caspase activity and apoptosis induced by Fas (CD95), bax, caspases, and anticancer drugs
-
Tamm I, Wang Y, Sausville E, Scudiero DA, Vigna N, et al. (1998) IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res 58: 5315-5320. (Pubitemid 28551107)
-
(1998)
Cancer Research
, vol.58
, Issue.23
, pp. 5315-5320
-
-
Tamm, I.1
Wang, Y.2
Sausville, E.3
Scudiero, D.A.4
Vigna, N.5
Oltersdorf, T.6
Reed, J.C.7
-
32
-
-
79958237620
-
Targeting survivin in cancer: The cell-signalling perspective
-
Kanwar JR, Kamalapuram SK, Kanwar RK (2011) Targeting survivin in cancer: the cell-signalling perspective. Drug Discov Today 16: 485-494.
-
(2011)
Drug Discov Today
, vol.16
, pp. 485-494
-
-
Kanwar, J.R.1
Kamalapuram, S.K.2
Kanwar, R.K.3
-
33
-
-
84864740325
-
Survivin is required for Beta-cell mass expansion in the pancreatic duct-ligated mouse model
-
Wu X, Zhang Q, Wang X, Zhu J, Xu K, et al. (2012) Survivin is required for Beta-cell mass expansion in the pancreatic duct-ligated mouse model. PLoS ONE 7: e41976.
-
(2012)
PLoS ONE
, vol.7
-
-
Wu, X.1
Zhang, Q.2
Wang, X.3
Zhu, J.4
Xu, K.5
-
34
-
-
58149350345
-
Postnatal expansion of the pancreatic beta-cell mass is dependent on survivin
-
Jiang Y, Nishimura W, Devor-Henneman D, Kusewitt D, Wang H, et al. (2008) Postnatal expansion of the pancreatic beta-cell mass is dependent on survivin. Diabetes 57: 2718-2727.
-
(2008)
Diabetes
, vol.57
, pp. 2718-2727
-
-
Jiang, Y.1
Nishimura, W.2
Devor-Henneman, D.3
Kusewitt, D.4
Wang, H.5
-
35
-
-
69949168807
-
Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice
-
Wu X, Wang L, Schroer S, Choi D, Chen P, et al. (2009) Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice. Diabetologia 52: 2130-2141.
-
(2009)
Diabetologia
, vol.52
, pp. 2130-2141
-
-
Wu, X.1
Wang, L.2
Schroer, S.3
Choi, D.4
Chen, P.5
-
36
-
-
33645519850
-
Inhibition of apoptosis by survivin improves transplantation of pancreatic islets for treatment of diabetes in mice
-
Dohi T, Salz W, Costa M, Ariyan C, Basadonna GP, et al. (2006) Inhibition of apoptosis by survivin improves transplantation of pancreatic islets for treatment of diabetes in mice. EMBO Rep 7: 438-443.
-
(2006)
EMBO Rep
, vol.7
, pp. 438-443
-
-
Dohi, T.1
Salz, W.2
Costa, M.3
Ariyan, C.4
Basadonna, G.P.5
-
37
-
-
24344472140
-
EGFR enhances Survivin expression through the phosphoinositide 3 (PI-3) kinase signaling pathway
-
DOI 10.1016/j.yexmp.2005.05.002, PII S0014480005000511
-
Wang Q, Greene MI (2005) EGFR enhances Survivin expression through the phosphoinositide 3 (PI-3) kinase signaling pathway. Exp Mol Pathol 79: 100-107. (Pubitemid 41262491)
-
(2005)
Experimental and Molecular Pathology
, vol.79
, Issue.2
, pp. 100-107
-
-
Wang, Q.1
Greene, M.I.2
-
39
-
-
19944431623
-
EGF-induced proliferation of adult human pancreatic duct cells is mediated by the MEK/ERK cascade
-
DOI 10.1038/labinvest.3700204
-
Rescan C, Le Bras S, Lefebvre VH, Frandsen U, Klein T, et al. (2005) EGF-induced proliferation of adult human pancreatic duct cells is mediated by the MEK/ERK cascade. Lab Invest 85: 65-74. (Pubitemid 40128041)
-
(2005)
Laboratory Investigation
, vol.85
, Issue.1
, pp. 65-74
-
-
Rescan, C.1
Le, B.S.2
Lefebvre, V.H.3
Frandsen, U.4
Klein, T.5
Foschi, M.6
Pipeleers, D.G.7
Scharfmann, R.8
Madsen, O.D.9
Heimberg, H.10
-
40
-
-
84894504926
-
Epidermal Growth Factor Receptor Signaling Promotes Pancreatic b-Cell Proliferation in Response to Nutrient Excess in Rats through mTOR and FOXM1
-
doi:10.2337/db13-0425
-
Zarrouki B, Benterki I, Fontés G, Peyot M-L, Seda O, et al. (2013) Epidermal Growth Factor Receptor Signaling Promotes Pancreatic b-Cell Proliferation in Response to Nutrient Excess in Rats through mTOR and FOXM1. Diabetes. doi:10.2337/db13-0425.
-
(2013)
Diabetes
-
-
Zarrouki, B.1
Benterki, I.2
Fontés, G.3
Peyot, M.-L.4
Seda, O.5
|