MicroRNA 145 may play an important role in uveal melanoma cell growth by potentially targeting insulin receptor substrate-1

Chinese Medical Journal

Volumn 127, Issue 8, 2014, Pages 1410-1416

  Li, Yang ^a,b   Huang, Qi Ming ^a,b   Shi, Xue Hui ^a,b   Jin, Xiang ^a,b   Shen, Li ^c,d   Xu, Xiao Lin ^a,b   Wei, Wen Bin ^a,b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Beijing Ophthalmology and Visual Science Key Laboratory   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^d PEKING UNIVERSITY   (China)

Author keywords

Insulin receptor substrate 1; MicroRNA array; miR 145; Uveal melanoma

Indexed keywords

INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MICRORNA 145; SOMATOMEDIN C RECEPTOR; INSULIN RECEPTOR SUBSTRATE; MICRORNA;

ADULT; APOPTOSIS; ARTICLE; CELL CYCLE; CELL FUNCTION; CELL GROWTH; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE SILENCING; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; MALE; MIDDLE AGED; PROTEIN EXPRESSION; PROTEIN MICROARRAY; REAL TIME POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY; UPREGULATION; UVEA MELANOMA; WESTERN BLOTTING; GENETICS; IN VITRO STUDY; MELANOMA; METABOLISM; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; TUMOR CELL LINE; UVEA TUMOR;

APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; IN VITRO TECHNIQUES; INSULIN RECEPTOR SUBSTRATE PROTEINS; MELANOMA; MICRORNAS; POLYMERASE CHAIN REACTION; UVEAL NEOPLASMS;

EID: 84898878037     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.20133206     Document Type: Article

References (31)

1. He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004; 5: 522-531.
2. Bartel DP. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
3. Croce CM, Calin GA. MiRNAs, cancer, and stem cell division. Cell 2005; 122: 6-7.
4. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature 2005; 435: 834-838.
5. Yang X, Lee Y, Fan H, Sun X, Lussier YA. Identification of common microRNA-mRNA regulatory biomodules in human epithelial cancers. Chin Sci Bull 2010; 55: 3576-3589.
6. Esquela-Kerscher A, Slack FJ. Oncomirs-microRNAs with a role in cancer. Nature Rev Cancer 2006; 6: 857-866.
7. Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005; 65: 7065-7070.
8. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006; 103: 2257-2261.
9. Dynoodt P, Speeckaert R, De Wever O, Chevolet I, Brochez L, Lambert J, et al. Mir-145 overexpression suppresses the migration and invasion of metastatic melanoma cell. Int J Oncol 2013; 42: 1443-1451.
10. Hurst EA, Harbour JW, Cornelius LA. Ocular melanoma: a review and the relationship to cutaneous melanoma. Arch Dermatol 2003; 139: 1067-1073.
11. Bakalian S, Marshall JC, Logan P, Faingold D, Maloney S, Di Cesare S, et al. Molecular pathways mediating liver metastasis in patients with uveal melanoma. Clin Cancer Res 2008; 14: 951-956.
12. Harbour JW. Clinical overview of uveal melanoma: introduction to tumors of the eye. In: Albert DM, Polans A, eds. Ocular oncology; New York: Marcel Dekker; 2003: 1-18.
13. Zhou J, Wang W. Analysis of microRNA expression profiling identifies microRNA-503 regulates metastatic function in hepatocellular cancer cell. J Surg Oncol 2011; 104: 278-283.
14. Kuo TY, His E, Yang IP, Tsai PC, Wang JY, Juo SHH. Computational analysis of mRNA expression profiles identifies MicroRNA-29a/c as Predictor of Colorectal Cancer Early Recurrence. PLoS One 2012; 7: e31587.
15. Worley LA, Long MD, Onken MD, Harbour JW. Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling. Melanoma Res 2008; 18: 184-190.
16. Yang CH, Wei WB. The miRNA expression profile of the uveal melanoma. Sci China Life Sci 2011; 54: 351-358.
17. Lin SA, Lyons MJ, Scherrer JF, Griffith K, True WR, Goldberg J, et al. Familial influences on gambling behavior: an analysis of 3359 twin pairs. Addiction 1998; 93: 1375-1384.
18. Bedikian AY. Metastatic uveal melanoma therapy: current options. Int Ophthalmol Clin 2006; 46: 151-166.
19. Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 2007; 39: 673-677.
20. Roldo C, Missiaglia E, Hagan JP, Falconi M, Capelli P, Bersani S, et al. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behaviour. J Clin Oncol 2006; 24: 4677-4684.
21. Yan D, Zhou X, Chen X, Hu DN, Dong XD, Wang J, et al. MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met. Invest Ophthalmol Vis Sci 2009; 50: 1559-1565.
22. Dong F, Lou DH. MicroRNA-34b/c suppresses uveal melanoma cell proliferation and migration through multiple targets. Mol Vis 2012; 18: 537-546.
23. Yan D, Dong XD, Chen X, Yao S, Wang L, Wang J, et al. Role of microrna-182 in posterior uveal melanoma: regulation of tumor development through MITF, BCL2 and Cyclin D2. PLoS One 2012; 7: e40967.
24. Liu N, Sun Q, Chen J, Li J, Zeng Y, Zhai S, et al. MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-κβ1 pathway. Oncol Rep 2012; 28: 961-968.
25. Ostenfeld MS, Bramsen JB, Lamy P, Villadsen SB, Fristrup N, Sørensen KD, et al. miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors. Oncogene 2010; 29: 1073-1084.
26. Hart M, Wach S, Nolte E, Szczyrba J, Menon R, Taubert H, et al. The proto-oncogene ERG is a target of microRNA miR-145 in prostate cancer. FEBS J 2013; 280: 2105-2116.
27. Hu J, Guo H, Li H, Liu Y, Liu J, Chen L, et al. MiR-145 regulates epithelial to mesenchymal transition of breast cancer cells by targeting Oct4. PLoS One 2012; 7: e45965.
28. Longato L, de la Monte S, Kuzushita N, Horimoto M, Rogers AB, Slagle BL, et al. Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver. Hepatology 2009; 49: 1935-1943.
29. Mardilovich K, Pankratz SL, Shaw LM. Expression and function of the insulin receptor substrate proteins in cancer. Cell Commun Signal 2009; 7: 14.
30. Cesarone G, Garofalo C, Abrams MT, Igoucheva O, Alexeev V, Yoon K, et al. RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells. J Cell Biochem 2006; 98: 440-450.
31. Strömberg T, Ekman S, Girnita L, Dimberg LY, Larsson O, Axelson M, et al. IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells. Blood 2006; 107: 669-678.