Topical nasal lysine aspirin in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis with nasal polyposis

Expert Review of Clinical Immunology

Volumn 10, Issue 5, 2014, Pages 657-665

  Parikh, Abhijeet ^a   Scadding, Glenis K ^b  

^a ST MARY S HOSPITAL   (United Kingdom)

^b ROYAL NATIONAL THROAT NOSE AND EAR HOSPITAL   (United Kingdom)

Author keywords

aspirin sensitive; aspirin tolerant; desensitization; lysine aspirin; nasal polyps

Indexed keywords

ACETYLSALICYLIC ACID; LYSINE ASPIRIN; NONSTEROID ANTIINFLAMMATORY AGENT; STEROID; UNCLASSIFIED DRUG; ACETYLSALICYLIC ACID LYSINATE; LYSINE;

ADJUVANT THERAPY; ANGIONEUROTIC EDEMA; ASPIRIN EXACERBATED RESPIRATORY DISEASE; ASTHMA; CHEMOSENSITIVITY; CHRONIC RHINOSINUSITIS; DESENSITIZATION; DIAGNOSTIC TEST; DRUG SAFETY; DRUG STRUCTURE; FORCED EXPIRATORY VOLUME; GASTROINTESTINAL TOXICITY; HUMAN; INFLAMMATION; NOSE POLYP; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RHINITIS; SENSITIVITY AND SPECIFICITY; STEROID THERAPY; SYMPTOM; URTICARIA; ANALOGS AND DERIVATIVES; CHRONIC DISEASE; COMPLICATION; INTRANASAL DRUG ADMINISTRATION; NASAL POLYPS; SINUSITIS; TREATMENT OUTCOME;

ADMINISTRATION, INTRANASAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CHRONIC DISEASE; HUMANS; LYSINE; NASAL POLYPS; RHINITIS; SINUSITIS; TREATMENT OUTCOME;

EID: 84898854755     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/1744666X.2014.901889     Document Type: Review

References (60)

1. Wei CC, Adappa ND, Cohen NA. Use of topical nasal therapies in the management of chronic rhinosinusitis. Laryngoscope 2013; 123(10):2347-59
2. Vane JR. Aspirin and other antiinflammatory drugs. Thorax 2000;55:S3-9
3. Hirschberg W. Mittheilung uber ein Fall von Nebenwirkung des Aspirin. Dtsch Med Wochenschr 1902;28:416
4. Gilbert G. Unusual idiosyncrasy to aspirin. J Am Med Assoc 1911;LVI(17): 1262-2
5. Widal F, Abrami P, Lermoyez J. First complete description of the aspirin idiosyncrasy-asthma-nasal polyposis syndrome (plus urticaria)-1922 (with a note on aspirin desensitization). By F. Widal, P. Abrami, J. Lermoyez. J Asthma Off J Assoc Care Asthma 1987;24(5):297-300
6. Cooke RA. Allergy in drug idiosyncrasy. J Am Med Assoc 1919;73:759-60
7. Lamson RW, Thomas R. Some untoward effects of acetylsalicylic acid. J Am Med Assoc 1932;99(2):107-7
8. Prickman LE, Buchstein HF. Hypersensitivity to acetylsalicylic acid (aspirin). J Am Med Assoc 1937; 108(6):445-51
9. Samter M, Beers RF Jr. Intolerance to aspirin. Clinical studies and consideration of its pathogenesis. Ann Intern Med 1968; 68(5):975-83
10. Probst L, Stoney P, Jeney E, Hawke M. Nasal polyps, bronchial asthma, and aspirin sensitivity. J Otolaryngol 1992;21:60-2
11. Samter M, Beers RF Jr. Concerning the nature of intolerance to aspirin. J Allergy 1967;40(5):281-93
12. Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol 1971; 231(25):232-5
13. Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G, Zmuda A Aspirin-induced asthma. Hypersensitivity to fenoprofen and ibuprofen in relation to their inhibitory action on prostaglandin generation by different microsomal enzymic preparations. J Allergy Clin Immunol 1976; 58(1 PT 1):10-18
14. Kowalski ML, Asero R, Bavbek S, et al. Classification and practical approach to the diagnosis and management of hypersensitivity to nonsteroidal anti-inflammatory drugs. Allergy 2013; 68(10):1219-32
15. Scadding G. Current management of aspirin-exacerbated respiratory disease. Prescriber 2012;23(13-14):26-32
16. Nizankowska E, Bestynska-Krypel A, Cmiel A, Szczeklik A. Oral and bronchial provocation tests with aspirin for diagnosis of aspirin-induced asthma. Eur Respir J 2000;15(5):863-9
17. Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G. Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. BMJ 1975; 1(5949):67-9
18. Mathison DA, Stevenson DD. Hypersensitivity to nonsteroidal antiinflammatory drugs: indications and methods for oral challenges. J Allergy Clin Immunol 1979;64(6 pt 2):669-74
19. Nizankowska-Mogilnicka E, Bochenek G, Mastalerz L, et al. EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity. Allergy 2007;62(10):1111-18
20. Bianco S, Robuschi M, Petrigni G. Aspirin induced tolerance in aspirin-asthma detected by a new challenge test. IRCS J Med Sci 1977;5:129-30
21. Schapowal AG, Simon HU, Schmitz-Schumann M. Phenomenology, pathogenesis, diagnosis and treatment of aspirin-sensitive rhinosinusitis. Acta Otorhinolaryngol Belg 1995;49(3): 235-50
22. Milewski M, Mastalerz L, Nizankowska E, Szczeklik A. Nasal provocation test with lysine-aspirin for diagnosis of aspirin-sensitive asthma. J Allergy Clin Immunol 1998;101(5):581-6
23. Casadevall J, Ventura PJ, Mullol J, Picado C. Intranasal challenge with aspirin in the diagnosis of aspirin intolerant asthma: evaluation of nasal response by acoustic rhinometry. Thorax 2000;55(11):921-4
24. Barranco P, Bobolea I, Larco JI, et al. Diagnosis of aspirin-induced asthma combining the bronchial and the oral challenge tests: a pilot study. J Invest Allergol Clin Immunol 2009;19(6):446-52
25. Miller B, Mirakian R, Gane S, et al. Nasal lysine aspirin challenge in the diagnosis of aspirin - exacerbated respiratory disease: asthma and rhinitis. Clin Exp Allergy J Br Soc Allergy Clin Immunol 2013;43(8): 874-80
26. Ortolani C, Mirone C, Fontana A, et al. Study of mediators of anaphylaxis in nasal wash fluids after aspirin and sodium metabisulfite nasal provocation in intolerant rhinitic patients. Ann Allergy 1987; 59(5 Pt 2):106-12
27. Ferreri NR, Howland WC, Stevenson DD, Spiegelberg HL. Release of leukotrienes, prostaglandins, and histamine into nasal secretions of aspirin-sensitive asthmatics during reaction to aspirin. Am Rev Respir Dis 1988;137(4):847-54
28. Clement PA, van der Veken P, Verstraelen J, et al. Recurrent polyposis nasi. Documentation. Rhinol 1989;8:5-14
29. Pawlowicz A, Williams WR, Davies BH. Inhalation and nasal challenge in the diagnosis of aspirin-induced asthma. Allergy 1991;46(6):405-9
30. Picado C, Ramis I, Rosellò J, et al. Release of peptide leukotriene into nasal secretions after local instillation of aspirin in aspirin-sensitive asthmatic patients. Am Rev Respir Dis 1992;145(1):65-9
31. Patriarca G, Nucera E, DiRienzo V, et al. Nasal provocation test with lysine acetylsalicylate in aspirin-sensitive patients. Ann Allergy 1991;67(1):60-2
32. Stevenson DD, Simon RA, Mathison DA. Aspirin-sensitive asthma: tolerance to aspirin after positive oral aspirin challenges. J Allergy Clin Immunol 1980;66(1):82-8
33. Pleskow WW, Stevenson DD, Mathison DA, et al. Aspirin desensitization in aspirin-sensitive asthmatic patients: clinical manifestations and characterization of the refractory period. J Allergy Clin Immunol 1982;69(1 Pt 1): 11-19
34. Kowalski ML, Grzelewska-Rzymowska I, Rozniecki J, Szmidt M. Aspirin tolerance induced in aspirin-sensitive asthmatics. Allergy 1984;39(3):171-8
35. Chiu JT. Improvement in aspirin-sensitive asthmatic subjects after rapid aspirin desensitization and aspirin maintenance (ADAM) treatment. J Allergy Clin Immunol 1983;71(6):560-7
36. Lumry WR, Curd JG, Zeiger RS, et al. Aspirin-sensitive rhinosinusitis: the clinical syndrome and effects of aspirin administration. J Allergy Clin Immunol 1983;71(6): 580-7
37. Stevenson DD, Pleskow WW, Simon RA, et al. Aspirin-sensitive rhinosinusitis asthma: a double-blind crossover study of treatment with aspirin. J Allergy Clin Immunol 1984; 73(4):500-7
38. Sweet JM, Stevenson DD, Simon RA, Mathison DA. Long-term effects of aspirin desensitization-treatment for aspirin-sensitive rhinosinusitis-asthma. J Allergy Clin Immunol 1990;85(1 Pt 1):59-65
39. Stevenson DD, Hankammer MA, Mathison DA, et al. Aspirin desensitization treatment of aspirin-sensitive patients with rhinosinusitis-asthma: long-term outcomes. J Allergy Clin Immunol 1996;98(4): 751-8
40. Gosepath J, Schaefer D, Amedee RG, Mann WJ. Individual monitoring of aspirin desensitization. Arch Otolaryngol Head Neck Surg 2001;127(3):316-21
41. Gosepath J, Schäfer D, Mann WJ. [Aspirin sensitivity: long term follow-up after up to 3 years of adaptive desensitization using a maintenance dose of 100 mg of aspirin a day]. Laryngorhinootologie 2002;81(10): 732-8
42. Rozsasi A, Polzehl D, Deutschle T, et al. Long-term treatment with aspirin desensitization: a prospective clinical trial comparing 100 and 300 mg aspirin daily. Allergy 2008;63(9):1228-34
43. Berges-Gimeno MP, Simon RA, Stevenson DD. Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 2003;111(1): 180-6
44. Fruth K, Pogorzelski B, Schmidtmann I, et al. Low-dose aspirin desensitization in individuals with aspirin-exacerbated respiratory disease. Allergy 2013;68(5): 659-65
45. Havel M, Ertl L, Braunschweig F, et al. Sinonasal outcome under aspirin desensitization following functional endoscopic sinus surgery in patients with aspirin triad. Eur Arch Otorhinolaryngol 2013;270(2):571-8
46. Comert S, Celebioglu E, Yucel T, et al. Aspirin 300 mg/day is effective for treating aspirin-exacerbated respiratory disease. Allergy 2013;68:1443-51
47. Berges-Gimeno MP, Simon RA, Stevenson DD. Early effects of aspirin desensitization treatment in asthmatic patients with aspirin-exacerbated respiratory disease. Ann Allergy Asthma Clin Immunol 2003;90(3):338-41
48. Lee JY, Simon RA, Stevenson DD. Selection of aspirin dosages for aspirin desensitization treatment in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 2007;119(1): 157-64
49. Patriarca G, Bellioni P, Nucera E, et al. Intranasal treatment with lysine acetylsalicylate in patients with nasal polyposis. Ann Allergy 1991;67(6): 588-92
50. Nucera E, Schiavino D, Milani A, et al. Effects of lysine- acetylsalicylate (LAS) treatment in nasal polyposis: two controlled long term prospective follow up studies. Thorax 2000;55(Suppl 2):S75-8
51. Parikh AA, Scadding GK. Intranasal lysine-aspirin in aspirin-sensitive nasal polyposis: a controlled trial. Laryngoscope 2005; 115(8):1385-90
52. Ogata N, Darby Y, Scadding G. Intranasal lysine-aspirin administration decreases polyp volume in patients with aspirin-intolerant asthma. J Laryngol Otol 2007;121(12): 1156-60
53. Sousa AR, Parikh A, Scadding G, et al. Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitis. N Engl J Med 2002;347(19):1493-9
54. Scadding GK, Hassab M, Darby YC, et al. Intranasal lysine aspirin in recurrent nasal polyposis. Clin Otolaryngol Allied Sci 1995; 20(6):561-3
55. Fokkens WJ, Lund VJ, Mullol J, et al. European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Rhinol Suppl. 2012;23(3)1-298;p preceding table of contents
56. Lee RU, Stevenson DD. Aspirin-exacerbated respiratory disease: evaluation and management. Allergy Asthma Immunol Res 2011;3(1):3-10
57. Steinhubl SR, Bhatt DL, Brennan DM, et al. Aspirin to prevent cardiovascular disease: the association of aspirin dose and clopidogrel with thrombosis and bleeding. Ann Intern Med 2009;150(6): 379-86
58. Wang X, Zhang N, Glorieux S, et al. Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue. PLoS One 2012;7(6):e39875
59. Juul-Möller S, Edvardsson N, Jahnmatz B, et al. Double-blind trial of aspirin in primary prevention of myocardial infarction in patients with stable chronic angina pectoris. The Swedish Angina Pectoris Aspirin Trial (SAPAT) Group. Lancet 1992; 340(8833):1421-5
60. Rothwell PM, Fowkes FGR, Belch JFF, et al. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011;377(9759):31-41