Use of topical nasal therapies in the management of Chronic rhinosinusitis

Laryngoscope

Volumn 123, Issue 10, 2013, Pages 2347-2359

  Wei, Calvin C ^a   Adappa, Nithin D ^b   Cohen, Noam A ^b  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

antibiotics; antifungals; antimicrobials; Chronic rhinosinusitis; nasal irrigations; topical therapy

Indexed keywords

AMPHOTERICIN B; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; BECLOMETASONE; BECLOMETASONE DIPROPIONATE; BUDESONIDE; CETIRIZINE; CORTICOSTEROID; DEXAMETHASONE; FLUTICASONE PROPIONATE; HYPERTONIC SOLUTION; HYPOTONIC SOLUTION; ISOTONIC SOLUTION; MOMETASONE FUROATE; MUCOLYTIC AGENT; NEOMYCIN; NOSE SPRAY; SODIUM CHLORIDE; TIXOCORTOL PIVALATE; TOBRAMYCIN; TRAMAZOLINE; TRIAMCINOLONE;

ANTIBIOTIC THERAPY; CHRONIC RHINOSINUSITIS; COMPUTER ASSISTED TOMOGRAPHY; CORTICOSTEROID THERAPY; DEBRIDEMENT; DRUG EFFICACY; ENDOSCOPIC SINUS SURGERY; ENDOSCOPY; EPISTAXIS; FACE PAIN; HEADACHE; HUMAN; META ANALYSIS; META ANALYSIS (TOPIC); MONOTHERAPY; MUCOCILIARY CLEARANCE; NASAL LAVAGE; NEBULIZATION; NOSE AIRWAY RESISTANCE; NOSE OBSTRUCTION; NOSE POLYP; NOSE SECRETION; PEAK NASAL INSPIRATORY FLOW; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENCE RISK; REFLEXOLOGY; RELAPSE; REVIEW; SIDE EFFECT; SINUSITIS; SYSTEMATIC REVIEW; TOPICAL TREATMENT; WEIGHT GAIN;

ANTIBIOTICS; ANTIFUNGALS; ANTIMICROBIALS; CHRONIC RHINOSINUSITIS; NASAL IRRIGATIONS; TOPICAL THERAPY;

ANTIFUNGAL AGENTS; BUDESONIDE; CHRONIC DISEASE; GLUCOCORTICOIDS; HUMANS; NASAL SPRAYS; RHINITIS; SINUSITIS;

EID: 84884974900     PISSN: 0023852X     EISSN: 15314995     Source Type: Journal    
DOI: 10.1002/lary.24066     Document Type: Review

References (73)

1. Rosenfeld RM, Andes D, Bhattacharyya N, et al. Clinical practice guideline: adult sinusitis. Otolaryngol Head Neck Surg 2007; 137: S1-S31.
2. Bachmann G, Hommel G, Michel O,. Effect of irrigation of the nose with isotonic salt solution on adult patients with chronic paranasal sinus disease. Eur Arch Otorhinolaryngol 2000; 257: 537-541.
3. Cordray S, Harjo JB, Miner L,. Comparison of intranasal hypertonic Dead Sea saline spray and intranasal aqueous triamcinolone spray in seasonal allergic rhinitis. Ear Nose Throat 2005; 84: 426-430.
4. Garavello W, Romagnoli M, Sordo L, et al. Hypersaline nasal irrigation in children with symptomatic seasonal allergic rhinitis: a randomized study. Pediatric Allergy Immunol 2003; 14: 140-143.
5. Garavello W, Di Berardino F, Romagnoli M, et al. Nasal rinsing with hypertonic solution: an adjunctive treatment for pediatric seasonal allergic rhinoconjunctivitis. Intern Arch Allergy Immunol 2005; 137: 310-314.
6. Heatley DG, McConnell KE, Kille TL, et al. Nasal irrigation for the alleviation of sinonasal symptoms. Otolaryngol Head Neck Surg 2001; 125: 44-48.
7. Rabago D, Zgierska A, Mundt M, et al. Efficacy of daily hypertonic saline nasal irrigation among patients with sinusitis: a randomized controlled trial. J Family Practice 2002: 51: 1049-1055.
8. Rogkakou A, Guerra L, Massacane P, et al. Effects on symptoms and quality of life of hypertonic saline nasal spray added to antihistamine in persistent allergic rhinitis-a randomized controlled study. Eur Ann Allergy Clin Immunol 2005; 37: 353-356.
9. Shoseyov D, Bibi H, Shai P, et al. Treatment with hypertonic saline versus normal saline nasal wash of pediatric chronic sinusitis. J Allergy Clin Immunol 1998; 101: 602-605.
10. Pynnonen MA, Mukerji SS, Kim HM, et al. Nasal saline for chronic sinonasal symptoms. Arch Otolaryngol Head Neck Surg 2007; 133: 1115-1120.
11. Hauptman G, Ryan MW,. The effect of saline solutions on nasal patency and mucociliary clearance in rhinosinusitis patients. Otolaryngol Head Neck Surg 2007; 137: 815-821.
12. Mohammadian P, Schaefer D, Hummel T, et al. Experimentally induced nasal irritation. Rhinology 1999; 37: 175-178.
13. Fooanant S, Chaiyasate S, Roongrotwattanasiri K,. Comparison on the efficacy of dexpanthenol in sea water and saline in postoperative endoscopic sinus surgery. J Med Assoc Thai 2008; 91: 1558-1563.
14. Freeman SR, Sivayoham ES, Jepson K, et al. A preliminary randomised controlled trial evaluating the efficacy of saline douching following endoscopic sinus surgery. Clin Otolaryngol 2008; 33: 462-465.
15. Liang KL, Su MC, Tseng HC, et al. Impact of pulsatile nasal irrigation on the prognosis of functional endoscopic sinus surgery. J Otolaryngol Head Neck Surg 2008; 37: 148-153.
16. Pigret D, Jankowski R,. Management of post-ethmoidectomy crust formation: randomized single-blind clinical trial comparing pressurized seawater versus antiseptic/mucolytic saline. Rhinology 1996; 34: 38-40.
17. Pinto JM, Elwany S, Baroody FM, et al. Effects of saline spray on symptoms after endoscopic sinus surgery. Am J Rhinol 2006; 20: 191-196.
18. Staffieri A, Marino F, Staffieri C, et al. The effects of sulfurous-arsenical-ferruginous thermal water nasal irrigation in wound healing after functional endoscopic sinus surgery for chronic rhinosinusitis: a prospective randomized study. Am J Otolaryngol 2008; 29: 223-229.
19. Harvey RJ, Hannan SA, Badia L, et al. Nasal saline irrigations for the symptoms of chronic rhinosinusitis. Cochrane Database Syst Rev 2007; 3: CD006394.
20. Rudmik L, Soler ZM, Orlandi RR,. Early postoperative care following endoscopic sinus surgery: an evidence based review with recommendations. Int Forum Allergy Rhinol 2011; 1: 417-430.
21. Desrosiers M, Bendouah Z, Barbeau J,. Effectiveness of topical antibiotics on staphylococcus aureus biofilm in vitro. Am J Rhinol 2007; 21: 149-153.
22. Uren B, Psaltis A, Wormald P,. Nasal lavage with mupirocin for the treatment of surgically recalcitrant chronic rhinosinusitis. Laryngoscope 2008; 118: 1677-1680.
23. Lim M, Citardi MJ, Leong J,. Topical antimicrobials in the management of chronic rhinosinusitis: a systematic review. Am J Rhinol 2008; 22: 381-389.
24. Leonard DW, Bolger WE,. Topical antibiotic therapy for recalcitrant sinusitis. Otolaryngol Head Neck Surg 2002; 127: 558-568.
25. Neher A, Fischer H, Appenroth E, et al. Tolerability of N-chlorotaurine in chronic rhinosinusitis applied via yamik catheter. Auris Nasus Larynx 2005; 32: 359-364.
26. Solares CA, Batra PS, Hall GS, et al. Treatment of chronic rhinosinusitis exacerbations due to methicillin-resistant staphylococcus aureus with mupirocin irrigations. Am J Otolaryngol 2006; 27: 161-165.
27. Kobayashi T, Baba S,. Topical use of antibiotics for paranasal sinusitis. Rhinol SUPPL. 1992; 14: 77-81.
28. Kamijyo A, Matsuzaki Z, Kikushima K, et al. Fosfomycin nebulizer therapy to chronic sinusitis. Auris Nasus Larynx 2001; 28: 227-232.
29. Scheinberg PA, Otsuji A,. Nebulized antibiotics for the treatment of acute exacerbations of chronic rhinosinusitis. Ear Nose Throat J 2002; 81: 648-652.
30. Moss RB, King VV,. Management of sinusitis in cystic fibrosis by endoscopic surgery and serial antimicrobial lavage: reduction in recurrence requiring surgery. Arch Otolaryngol Head Neck Surg 1995; 121: 566-572.
31. Vaughan WC, Carvalho G,. Use of nebulized antibiotics for acute infections in chronic sinusitis. Otolaryngol Head Neck Surg 2002; 127: 558-561.
32. Sykes DA, Wilson R, Chan KL, et al. Relative importance of antibiotic and improved clearance in topical treatment of chronic mucopurulent rhinosinusitis: a controlled study. Lancet 1986; 2: 359-360.
33. Desrosiers MY, Salas-Prato M,. Treatment of chronic rhinosinusitis refractory to other treatments with topical antibiotic therapy delivered by means of a large-particle nebulizer: results of a controlled trial. Otolaryngol Head Neck Surg 2001; 125: 265-269.
34. Ponikau JU, Sherris DA, Weaver A,. Treatment of chronic rhinosinusitis with intranasal amphotericin B: a randomized, placebo-controlled, double-blind pilot trial. J Allergy Clin Immunol 2005; 115: 125-131.
35. Weschta M, Rimek D, Formanek M, et al. Topical antifungal treatment of chronic rhinosinusitis with nasal polyps: a randomized, double-blind clinical trial. J Allergy Clin Immunol 2004; 113: 1122-1128.
36. Ebbens FA, Scadding GK, Badia L, et al. Amphotericin B nasal lavages: not a solution for patients with chronic rhinosinusitis. J Allergy Clin Immunol 2006; 118: 1149-1156.
37. Gerlinger I, Fittler A, Fonai F, et al. Postoperative application of amphotericin B nasal spray in chronic rhinosinusitis with nasal polyposis, with a review of the antifungal therapy. Eur Arch Otorhinolaryngol 2009; 266: 847-855.
38. Ponikau JU, Sherris DA, Kita H, et al. Intranasal antifungal treatment in 51 patients with chronic rhinosinusitis. J Allergy Clin Immunol 2002; 110: 862-866.
39. Meltzer EO, Hamilos DL, Hadley JA, et al. Rhinosinusitis: establishing definitions for clinical research and patient care. Otolaryngol Head Neck Surg 2004; 131 (SUPPL. 6): S1-S62.
40. Badia L, Lund V,. Topical corticosteroids in nasal polyposis. Drugs 2001; 61: 573-578.
41. Zalmanovici A, Yaphe J,. Intranasal steroids for acute sinusitis. Cochrane Database Syst Rev. 2009; 7: CD005149.
42. Joe SA, Thambi R, Huang J,. A systematic review of the use of intranasal steroids in the treatment of chronic rhinosinusitis. Otolaryngol Head Neck Surg 2008; 139: 340-347.
43. Kalish LH, Arendts G, Sacks R, et al. Topical steroids in chronic rhinosinusitis without polyps: a systematic review and meta-analysis. Otolaryngol Head Neck Surg 2009; 141: 674-683.
44. Stjarne P, Blomgren K, Caye-Thomasen P, et al. The efficacy and safety of once-daily mometasone furoate nasal spray in nasal polyposis: a randomized, double-blind, placebo-controlled study. Acta Otolaryngol 2006; 126: 606-612.
45. Stjarne P, Mosges R, Jorissen M, et al. Randomized controlled trial of mometasone furoate nasal spray for the treatment of nasal polyposis. Arch Otolaryngol Head Neck Surg 2006; 132: 179-185.
46. Butkus Small C, Hernandez J, Reyes A, et al. Efficacy and safety of mometasone furoate nasal spray in nasal polyposis. J Allergy Clin Immunol 2005; 116: 1275-1281.
47. Jankowski R, Schrewelius C, Bonfils P, et al. Efficacy and tolerability of budesonide aqueous nasal spray treatment in patients with nasal polyps. Arch Otolaryngol Head Neck Surg 2001; 127: 447-452.
48. Filiaci F, Passali D, Puxeddu R, et al. A randomized controlled trial showing efficacy of once daily intranasal budesonide in nasal polyposis. Rhinology 2000; 38: 185-190.
49. Keith P, Nieminen J, Hollingworth K, et al. Efficacy and tolerability of fluticasone propionate nasal drops 400 ug once daily compared with placebo for the treatment of bilateral polyposis in adults. Clin Exp Allergy 2000; 30: 1460-1468.
50. Penttilae M, Poulsen P, Hollingworth K, et al. Dose-related efficacy and tolerability of fluticasone propionate nasal drops 400 ug once daily and twice daily in the treatment of bilateral nasal polyposis: a placebo-controlled randomized study in adult patients. Clin Exp Allergy 2000; 30: 94-102.
51. Tos M, Svendstrup F, Arndal H, et al. Efficacy of an aqueous and a powder formulation of nasal budesonide compared in patients with nasal polyps. Am J Rhinol 1998; 12: 183-189.
52. Lund V, Flood J, Sykes AP, et al. Effect of fluticasone in severe polyposis. Arch Otolaryngol Head Neck Surg 1998; 124: 513-518.
53. Holmberg K, Juliusson S, Balder B, et al. Fluticasone propionate aqueous nasal spray in the treatment of nasal polyposis. Ann Allergy Asthma Immunol 1997; 78: 270-278.
54. Lildholdt T, Rundcrantz H, Lindqvist N,. Efficacy of topical corticosteroid powder for nasal polyps: a double-blind, placebo-controlled study of budesonide. Clin Otolaryngol Allied Sci 1995; 20: 26-30.
55. Johansen LV, Illum P, Kristensen S, et al. The effect of budesonide (Rhinocort) in the treatment of small and medium-sized nasal polyps. Clin Otolaryngol 1993; 18: 524-527.
56. Ruhno J, Andersson B, Denburg J, et al. A double-blind comparison of intranasal budesonide with placebo for nasal polyposis. J Allergy Clin Immunol 1990; 86: 946-953.
57. Lund VJ, Black JH, Szabo LZ, et al. Efficacy and tolerability of budesonide aqueous nasal spray in chronic rhinosinusitis patients. Rhinology 2004; 42: 57-62.
58. Dijkstra MD, Ebbens FA, Poublon RM, et al. Fluticasone propionate aqueous nasal spray does not influence the recurrence rate of chronic rhinosinusitis and nasal polyps 1 year after functional endoscopic sinus surgery. Clin Exp Allergy 2004; 34: 1395-1400.
59. Giger R, Pasche P, Cheseaux C, et al. Comparison of once- versus twice-daily use of beclomethasone dipropionate aqueous nasal spray in the treatment of allergic and non-allergic chronic rhinosinusitis. Eur Arch Otorhinolaryngol 2003; 260: 135-140.
60. Parikh A, Scadding GK, Darby Y, et al. Topical corticosteroids in chronic rhinosinusitis: a randomized, double-blind, placebo-controlled trial using fluticasone propionate aqueous nasal spray. Rhinology 2001; 39: 75-79.
61. Mastalerz L, Milewski M, Duplaga M, et al. Intranasal fluticasone propionate for chronic eosinophilic rhinitis in patients with aspirin-induced asthma. Allergy 1997; 52: 895-900.
62. Qvarnberg Y, Kantola O, Salo J, et al. Influence of topical steroid treatment on maxillary sinusitis. Rhinology 1992; 2: 359-360.
63. Lavigne F, Cameron L, Renzi PM, et al. Intrasinus administration of topical budesonide to allergic patients with chronic rhinosinusitis following surgery. Laryngoscope 2002; 112: 858-864.
64. Sykes DA, Wilson R, Chan KL, et al. Relative importance of antibiotic and improved clearance in topical treatment of chronic mucopurulent rhinosinusitis: a controlled study. Lancet 1986; 2: 359-360.
65. Cuenant G, Stipon JP, Plante-Longchamp G, et al. Efficacy of endonasal neomycin-tixocortol pivalate irrigation in the treatment of chronic allergic and bacterial sinusitis. J Otorhinolaryngol Relat Spec 1986; 48: 226-232.
66. Kang IG, Yoon BK, Jung JH, et al. The effect of high-dose topical corticosteroid therapy on prevention of recurrent nasal polyps after revision endoscopic sinus surgery. Am J Rhinol 2008; 22: 497-501.
67. Sachanandani NS, Piccirillo JF, Kramper MA, et al. The effect of nasally administered budesonide respules on adrenal cortex function in patients with chronic rhinosinusitis. Arch Otolaryngol Head Neck Surg 2009; 135: 303-307.
68. Bhalla RK, Payton K, Wright ED,. Safety of budesonide in saline sinonasal irrigations in the management of chronic rhinosinusitis with polyposis: lack of significant adrenal suppression. J Otolaryngol Head Neck Surg 2008; 37: 821-825.
69. Welch KC, Thaler ER, Doghramji LL, et al. The effects of serum and urinary cortisol levels of topical intranasal irrigations with budesonide added to saline in patients with recurrent polyposis after endoscopic sinus surgery. Am J Rhinol Allergy 2010; 24: 26-28.
70. Rowe-Jones JM, Medcalf M, Durham SR, et al. Functional endoscopic sinus surgery: 5 year follow up and results of a prospective, randomized, stratified, double-blind, placebo-controlled study of postoperative fluticasone propionate aqueous nasal spray. Rhinology 2005; 43: 2-10.
71. Jorissen M, Bachert C,. Effect of corticosteroids on wound healing after endoscopic sinus surgery. Rhinology 2009; 47: 280-286.
72. Stjarne P, Olsson P, Alenius M,. Use of mometasone furoate to prevent polyp relapse after endoscopic sinus surgery. Arch Otolaryngol Head Neck Surg 2009; 135: 296-302.
73. Schenkel EJ, Skoner DP, Bronsky EA, et al. Absence of growth retardation in children with perennial allergic rhinitis after one year of treatment with mometasone furoate aqueous nasal spray. Pediatrics 2000; 105: e22.