Minocycline resistance in an oral Streptococcus infantis isolate is encoded by tet(S) on a novel small, low copy number plasmid

FEMS Microbiology Letters

Volumn 353, Issue 2, 2014, Pages 106-115

  Ciric, Lena ^a,b   Brouwer, Michael S M ^a,c   Mullany, Peter ^a   Roberts, Adam P ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

IS1216; relBE; Tn6000; Toxin antitoxin

Indexed keywords

BACTERIAL TOXIN; MINOCYCLINE; RELE TOXIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL DNA;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIUM ISOLATION; CONTROLLED STUDY; GENE DOSAGE; GENE LOCATION; GENETIC CODE; GENOTYPE; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STREPTOCOCCUS; STREPTOCOCCUS INFANTIS; TETS GENE; TRANSPOSON; WILD TYPE; CHEMISTRY; DNA SEQUENCE; GENE DELETION; GENETICS; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY;

STREPTOCOCCUS INFANTIS;

ANTI-BACTERIAL AGENTS; BASE SEQUENCE; DNA, BACTERIAL; GENE DELETION; GENOTYPE; HUMANS; MICROBIAL SENSITIVITY TESTS; MINOCYCLINE; MOLECULAR SEQUENCE DATA; MUTATION; PLASMIDS; SEQUENCE ANALYSIS, DNA; STREPTOCOCCUS; TETRACYCLINE RESISTANCE;

EID: 84898849763     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/1574-6968.12410     Document Type: Article

References (26)

1. Andersson DI (2003) Persistence of antibiotic resistant bacteria. Curr Opin Microbiol 6: 452-456.
2. Brouwer MS, Mullany P & Roberts AP (2010) Characterization of the conjugative transposon Tn6000 from Enterococcus casseliflavus 664.1H1 (formerly Enterococcus faecium 664.1H1). FEMS Microbiol Lett 309: 71-76.
3. Charpentier E, Gerbaud G & Courvalin P (1993) Characterization of a new class of tetracycline-resistance gene tet(S) in Listeria monocytogenes BM4210. Gene 131: 27-34.
4. Chen YYM, Shieh HR, Lin CT & Liang SY (2011) Properties and construction of plasmid pFW213, a shuttle vector with the oral Streptococcus origin of replication. Appl Environ Microbiol 77: 3967-3974.
5. Ciric L, Mullany P & Roberts AP (2011) Antibiotic and antiseptic resistance genes are linked on a novel mobile genetic element: Tn6087. J Antimicrob Chemother 66: 2235-2239.
6. Ciric L, Ellatif M, Sharma P, Patel R, Song X, Mullany P & Roberts AP (2012) Tn916-like elements from human, oral, commensal streptococci possess a variety of antibiotic and antiseptic resistance genes. Int J Antimicrob Agents 39: 360-361.
7. Kazimierczak KA, Flint HJ & Scott KP (2006) Comparative analysis of sequences flanking tet(W) resistance genes in multiple species of gut bacteria. Antimicrob Agents Chemother 50: 2632-2639.
8. Lancaster H, Ready D, Mullany P, Spratt D, Bedi R & Wilson M (2003) Prevalence and identification of tetracycline-resistant oral bacteria in children not receiving antibiotic therapy. FEMS Microbiol Lett 228: 99-104.
9. Liu Y, Wang Y, Wu C, Shen Z, Schwarz S, Du XD, Dai L, Zhang W, Zhang Q & Shen J (2012a) First report of the multidrug resistance gene cfr in Enterococcus faecalis of animal origin. Antimicrob Agents Chemother 56: 1650-1654.
10. Liu Y, Wang Y, Schwarz S, Li Y, Shen Z, Zhang Q, Wu C & Shen J (2013) Transferable multiresistance plasmids carrying cfr in Enterococcus spp. From swine and farm environment. Antimicrob Agents Chemother 57: 42-48.
11. Nakamura M, Ogata K, Nagamine T, Tajima K, Matsui H & Benno Y (2001) The replicon of the cryptic Plasmid pSBO1 isolated from Streptococcus bovis JB1. Curr Microbiol 43: 11-16.
12. Novais C, Freitas AR, Silveira E, Baquero F, Peixe L, Roberts AP & Coque TM (2012) Different genetic supports for the tet(S) gene in enterococci. Antimicrob Agents Chemother 56: 6014-6018.
13. Palmieri C, Mingoia M & Varaldo PE (2013) Unconventional circularizable bacterial genetic structures carrying antibiotic resistance determinants. Antimicrob Agents Chemother 57: 2440-2441.
14. Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45.
15. Poyart C, Quesne G, Coulon S, Berche P & Trieu-Cuot P (1998) Identification of streptococci to species level by sequencing the gene encoding the manganese-dependent superoxide dismutase. J Clin Microbiol 36: 41-47.
16. Ready D, Lancaster H, Qureshi F, Bedi R, Mullany P & Wilson M (2004) Effect of amoxicillin use on oral microbiota in young children. Antimicrob Agents Chemother 48: 2883-2887.
17. Roberts AP & Mullany P (2011) Tn916-like genetic elements: a diverse group of modular mobile elements conferring antibiotic resistance. FEMS Microbiol Rev 35: 856-871.
18. Roberts AP, Davis IJ, Seville L, Villedieu A & Mullany P (2006) Characterization of the ends and target site of a novel tetracycline resistance-encoding conjugative transposon from Enterococcus faecium 664.1H1. J Bacteriol 188: 4356-4361.
19. Seville LA (2007) Searching for novel antibiotic resistance genes and their genetic supports in the oral and faecal microbiota of six European countries. PhD Thesis, University College London, London, UK.
20. Seville LA, Patterson AJ, Scott KP, Mullany P, Quail MA, Parkhill J, Ready D, Wilson M, Spratt D & Roberts AP (2009) Distribution of tetracycline and erythromycin resistance genes among human oral and fecal metagenomic DNA. Microb Drug Resist 15: 159-166.
21. Villedieu A, Diaz-Torres ML, Hunt N, McNab R, Spratt DA, Wilson M & Mullany P (2003) Prevalence of tetracycline resistance genes in oral bacteria. Antimicrob Agents Chemother 47: 878-882.
22. Villedieu A, Diaz-Torres ML, Roberts AP, Hunt N, McNab R, Spratt DA, Wilson M & Mullany P (2004) Genetic basis of erythromycin resistance in oral bacteria. Antimicrob Agents Chemother 48: 2298-2301.
23. Villedieu A, Roberts AP, Allen E, Hussain H, McNab R, Spratt DA, Wilson M & Mullany P (2007) Determination of the genetic support for tet(W) in oral bacteria. Antimicrob Agents Chemother 51: 2195-2197.
24. Wang Y, Li D, Song L, Liu Y, He T, Liu H, Wu C, Schwarz S & Shen J (2013) First report of the multiresistance gene cfr in Streptococcus suis. Antimicrob Agents Chemother 57: 4061-4063.
25. Warburton P, Ciric L, Lerner A, Seville LA, Roberts AP, Mullany P & Allan E (2013) TetAB46, a predicted heterodimeric ABC transporter conferring tetracycline resistance in Streptococcus australis isolated from the oral cavity. J Antimicrob Chemother 68: 17-22.
26. Warburton P, Roberts AP, Allan E, Seville L, Lancaster H & Mullany P (2009) Characterization of tet(32) genes from the oral metagenome. Antimicrob Agents Chemother 53: 273-276.