-
1
-
-
4143066760
-
Gefitinib sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
-
Sordella R, Bell DW, Haber DA and Settleman J: Gefitinib sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 305: 1163-1167, 2004.
-
(2004)
Science
, vol.305
, pp. 1163-1167
-
-
Sordella, R.1
Bell, D.W.2
Haber, D.A.3
Settleman, J.4
-
2
-
-
1142273472
-
Altered states: Selectively drugging the Hsp90 cancer chaperone
-
Workman P: Altered states: selectively drugging the Hsp90 cancer chaperone. Trends Mol Med 10: 47-51, 2004.
-
(2004)
Trends Mol Med
, vol.10
, pp. 47-51
-
-
Workman, P.1
-
3
-
-
84855459627
-
The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor
-
Kobayashi N, Toyooka S, Soh J, et al: The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor. Lung Cancer 75: 161-166, 2012.
-
(2012)
Lung Cancer
, vol.75
, pp. 161-166
-
-
Kobayashi, N.1
Toyooka, S.2
Soh, J.3
-
4
-
-
33746034167
-
Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib
-
Jackman DM, Yeap BY, Sequist LV, et al: Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib. Clin Cancer Res 12: 3908-3914, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3908-3914
-
-
Jackman, D.M.1
Yeap, B.Y.2
Sequist, L.V.3
-
5
-
-
32944481596
-
Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib
-
Riely GJ, Pao W, Pham D, et al: Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib. Clin Cancer Res 12: 839-844, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 839-844
-
-
Riely, G.J.1
Pao, W.2
Pham, D.3
-
6
-
-
0037037832
-
Clinical impact of novel treatment strategies
-
Giaccone G: Clinical impact of novel treatment strategies. Oncogene 21: 6970-6981, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 6970-6981
-
-
Giaccone, G.1
-
7
-
-
0032611444
-
Bioactive agents from natural sources: Trends in discovery and application
-
Grabley S and Thiericke R: Bioactive agents from natural sources: trends in discovery and application. Adv Biochem Eng Biotechnol 64: 101-154, 1999.
-
(1999)
Adv Biochem Eng Biotechnol
, vol.64
, pp. 101-154
-
-
Grabley, S.1
Thiericke, R.2
-
9
-
-
36549043882
-
In vitro anticancer activity of aqueous extracts and ethanol extracts of fifteen traditional Chinese medicines on human digestive tumor cell lines
-
Sun J, Liu BR, Hu WJ, et al: In vitro anticancer activity of aqueous extracts and ethanol extracts of fifteen traditional Chinese medicines on human digestive tumor cell lines. Phytother Res 21: 1102-1104, 2007.
-
(2007)
Phytother Res
, vol.21
, pp. 1102-1104
-
-
Sun, J.1
Liu, B.R.2
Hu, W.J.3
-
10
-
-
33646422206
-
Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft
-
Lee MS, Yuet-Wa JC, Kong SK, et al: Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft. Cancer Biol Ther 4: 1248-1254, 2005.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 1248-1254
-
-
Lee, M.S.1
Yuet-Wa, J.C.2
Kong, S.K.3
-
11
-
-
11144295689
-
Polyphyllin D is a potent apoptosis inducer in drug-resistant HepG2 cells
-
Cheung JY, Ong RC, Suen YK, et al: Polyphyllin D is a potent apoptosis inducer in drug-resistant HepG2 cells. Cancer Lett 217: 203-211, 2005.
-
(2005)
Cancer Lett
, vol.217
, pp. 203-211
-
-
Cheung, J.Y.1
Ong, R.C.2
Suen, Y.K.3
-
12
-
-
49749104260
-
Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): Induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways
-
Siu FM, Ma DL, Cheung YW, et al: Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways. Proteomics 8: 3105-3117, 2008.
-
(2008)
Proteomics
, vol.8
, pp. 3105-3117
-
-
Siu, F.M.1
Ma, D.L.2
Cheung, Y.W.3
-
13
-
-
84898836559
-
The effect of Chonglou Saponin I on proliferation and apoptosis in lung adenocarcinoma cell line PC9
-
Jiang H, Su D and Ma SL: The effect of Chonglou Saponin I on proliferation and apoptosis in lung adenocarcinoma cell line PC9. J Chinese Oncol 18: 166-169, 2012.
-
(2012)
J Chinese Oncol
, vol.18
, pp. 166-169
-
-
Jiang, H.1
Su, D.2
Ma, S.L.3
-
14
-
-
84873254934
-
Effect of Polyphyllin I on radiosensitivity in nasopharyngeal carcinoma cell line CNE-2 in vitro
-
In Chinese
-
Hua YH, Ma SL, Fu ZF, et al: Effect of Polyphyllin I on radiosensitivity in nasopharyngeal carcinoma cell line CNE-2 in vitro. Chinese Archives of Traditional Chinese Medicine 29: 1387-1390, 2011 (In Chinese).
-
(2011)
Chinese Archives of Traditional Chinese Medicine
, vol.29
, pp. 1387-1390
-
-
Hua, Y.H.1
Ma, S.L.2
Fu, Z.F.3
-
15
-
-
84862956109
-
Paris saponin I induces G2/M cell cycle arrest and apoptosis in human gastric carcinoma SGC7901 cells
-
Xiao M, Dai X, He X, et al: Paris saponin I induces G2/M cell cycle arrest and apoptosis in human gastric carcinoma SGC7901 cells. J Huazhong Univ Sci Technol Med Sci 31: 768-772, 2011.
-
(2011)
J Huazhong Univ Sci Technol Med Sci
, vol.31
, pp. 768-772
-
-
Xiao, M.1
Dai, X.2
He, X.3
-
16
-
-
66849095590
-
The antitumoral effect of Paris Saponin I associated with the induction of apoptosis through the mitochondrial pathway
-
Xiao X, Bai P, Bui Nguyen TM, et al: The antitumoral effect of Paris Saponin I associated with the induction of apoptosis through the mitochondrial pathway. Mol Cancer Ther 8: 1179-1188, 2009.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1179-1188
-
-
Xiao, X.1
Bai, P.2
Bui Nguyen, T.M.3
-
17
-
-
65549154851
-
In vitro and in vivo anticancer activity of steroid saponins of Paris polyphylla var. yunnanensis
-
Yan LL, Zhang YJ, Gao WY, et al: In vitro and in vivo anticancer activity of steroid saponins of Paris polyphylla var. yunnanensis. Exp Oncol 31: 27-32, 2009.
-
(2009)
Exp Oncol
, vol.31
, pp. 27-32
-
-
Yan, L.L.1
Zhang, Y.J.2
Gao, W.Y.3
-
18
-
-
70349113502
-
Combined treatment with TNF-alpha/gefitinib alleviates the resistance to gefitinib in PC-9 cells
-
Ji Y, Ma SL, Zhang YP, et al: Combined treatment with TNF-alpha/gefitinib alleviates the resistance to gefitinib in PC-9 cells. Anticancer Drugs 20: 832-837, 2009.
-
(2009)
Anticancer Drugs
, vol.20
, pp. 832-837
-
-
Ji, Y.1
Ma, S.L.2
Zhang, Y.P.3
-
19
-
-
0344142396
-
Emerging roles of caspase-3 in apoptosis
-
Porter AG and Jänicke RU: Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6: 99-104, 1999.
-
(1999)
Cell Death Differ
, vol.6
, pp. 99-104
-
-
Porter, A.G.1
Jänicke, R.U.2
-
20
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO: The biochemistry of apoptosis. Nature 407: 770-776, 2000.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
21
-
-
34547911450
-
Bcl-2 family members regulate anoxia-induced cell death
-
Shroff EH, Snyder C and Chandel NS: Bcl-2 family members regulate anoxia-induced cell death. Antioxid Redox Signal 9: 1405-1409, 2007.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 1405-1409
-
-
Shroff, E.H.1
Snyder, C.2
Chandel, N.S.3
-
22
-
-
9044225527
-
BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapy
-
Reed JC, Miyashita T, Takayama S, et al: BCL-2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy. J Cell Biochem 60: 23-32, 1996.
-
(1996)
J Cell Biochem
, vol.60
, pp. 23-32
-
-
Reed, J.C.1
Miyashita, T.2
Takayama, S.3
-
23
-
-
0029097470
-
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax
-
Sedlak TW, Oltvai ZN, Yang E, et al: Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci USA 92: 7834-7838, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7834-7838
-
-
Sedlak, T.W.1
Oltvai, Z.N.2
Yang, E.3
-
24
-
-
77951954388
-
Enhancement of radiosensitivity by CpG-oligodeoxyribonucleotide-7909 in human non-small cell lung cancer A549 cells
-
Zha L, Qiao T, Yuan S, et al: Enhancement of radiosensitivity by CpG-oligodeoxyribonucleotide-7909 in human non-small cell lung cancer A549 cells. Cancer Biother Radiopharm 25: 165-170, 2010.
-
(2010)
Cancer Biother Radiopharm
, vol.25
, pp. 165-170
-
-
Zha, L.1
Qiao, T.2
Yuan, S.3
-
25
-
-
41949139309
-
Induction of p21 by p65 in p53 null cells treated with Doxorubicin
-
Ma S, Tang J, Feng J, et al: Induction of p21 by p65 in p53 null cells treated with Doxorubicin. Biochim Biophys Acta 1783: 935-940, 2008.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 935-940
-
-
Ma, S.1
Tang, J.2
Feng, J.3
-
26
-
-
33750903389
-
Requirement for pre-existing of p21 to prevent doxorubicin-induced apoptosis through inhibition of caspase-3 activation
-
Tang JJ, Shen C and Lu YJ: Requirement for pre-existing of p21 to prevent doxorubicin-induced apoptosis through inhibition of caspase-3 activation. Mol Cell Biochem 291: 139-144, 2006.
-
(2006)
Mol Cell Biochem
, vol.291
, pp. 139-144
-
-
Tang, J.J.1
Shen, C.2
Lu, Y.J.3
-
27
-
-
0037059807
-
p21-activated kinase links Rac/Cdc42 signaling to merlin
-
Xiao GH, Beeser A, Chernoff J and Testa JR: p21-activated kinase links Rac/Cdc42 signaling to merlin. J Biol Chem 277: 883-886, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 883-886
-
-
Xiao, G.H.1
Beeser, A.2
Chernoff, J.3
Testa, J.R.4
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