Outcome of transplantation for acute lymphoblastic leukemia in children with down syndrome

Pediatric Blood and Cancer

Volumn 61, Issue 6, 2014, Pages 1126-1128

  Hitzler, Johann K ^a   He, Wensheng ^b   Doyle, John ^a   Cairo, Mitchell ^c   Camitta, Bruce M ^b   Chan, Ka Wah ^d   Perez, Miguel A Diaz ^e   Fraser, Christopher ^f   Gross, Thomas G ^g   Horan, John T ^h   Kennedy Nasser, Alana A ⁱ   Kitko, Carrie ^j   Kurtzberg, Joanne ^k   Lehmann, Leslie ^l   O'Brien, Tracey ^m   Pulsipher, Michael A ⁿ   Smith, Franklin O ^o   Zhang, Mei Jie ^b   Eapen, Mary ^b   Carpenter, Paul A ^p  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c NEW YORK MEDICAL COLLEGE   (United States)

^d TEXAS TRANSPLANT INSTITUTE   (United States)

^e HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS   (Spain)

^f ROYAL CHILDREN'S HOSPITAL   (Australia)

^g NATIONWIDE CHILDREN S HOSPITAL   (United States)

^h Children's Healthcare of Atlanta at Egleston   (United States)

ⁱ TEXAS CHILDREN S HOSPITAL   (United States)

^j UNIVERSITY OF MICHIGAN   (United States)

^k DUKE UNIVERSITY   (United States)

^l DANA FARBER CANCER INSTITUTE   (United States)

^m SYDNEY CHILDREN'S HOSPITAL   (Australia)

ⁿ Primary Children's Medical Center   (Australia)

^o UNIVERSITY OF CINCINNATI   (United States)

^p USA   (United States)

more..

Author keywords

Acute lymhoblastic leukemia; Down syndrome; Hematopoietic stem cell transplantation; Pediatric; Relapse; Trisomy 21

Indexed keywords

ACUTE LYMHOBLASTIC LEUKEMIA; DOWN SYNDROME; HEMATOPOIETIC STEM CELL TRANSPLANTATION; PEDIATRIC; RELAPSE; TRISOMY 21;

ADOLESCENT; ADULT; ALLOGRAFTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE MARROW TRANSPLANTATION; CHILD; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; CYCLOSPORINE; DISEASE-FREE SURVIVAL; DOWN SYNDROME; GENETIC PREDISPOSITION TO DISEASE; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT; KAPLAN-MEIER ESTIMATE; LIVING DONORS; MYELOABLATIVE AGONISTS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECURRENCE; REGISTRIES; REMISSION INDUCTION; RETROSPECTIVE STUDIES; SALVAGE THERAPY; TACROLIMUS; TRANSPLANTATION CONDITIONING; TREATMENT OUTCOME; WHOLE-BODY IRRADIATION;

EID: 84898801407     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.24918     Document Type: Article

References (18)

1. Borgmann A, von Stackelberg A, Hartmann R, et al. Unrelated donor stem cell transplantation compared with chemotherapy for children with acute lymphoblastic leukemia in a second remission: A matched-pair analysis. Blood 2003; 101:3835-3839.
2. Parker C, Waters R, Leighton C, et al. Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): An open-label randomised trial. Lancet 2010; 376:2009-2017.
3. Tallen G, Ratei R, Mann G, et al. Long-term outcome in children with relapsed acute lymphoblastic leukemia after time-point and site-of-relapse stratification and intensified short-course multidrug chemotherapy: Results of trial ALL-REZ BFM 90. J Clin Oncol 2011; 28:2339-2347.
4. Schrappe M, Hunger SP, Pui CH, et al. Outcomes after induction failure in childhood acute lymphoblastic leukemia. N Engl J Med 2012; 366:1371-1381.
5. Dini G, Zecca M, Balduzzi A, et al. No difference in outcome between children and adolescents transplanted for acute lymphoblastic leukemia in second remission. Blood 2011; 118:6683-6690.
6. Shaw PJ, Kan F, Woo Ahn K, et al. Outcomes of pediatric bone marrow transplantation for leukemia and myelodysplasia using matched sibling, mismatched related, or matched unrelated donors. Blood 2010; 116:4007-4015.
7. Maloney KW. Acute lymphoblastic leukaemia in children with Down syndrome: An updated review. Br J Hematol 2011; 155:420-425.
8. Meyr F, Escherich G, Mann G, et al. Outcomes of treatment for relapsed acute lymphoblastic leukaemia in children with Down syndrome. Br J Hematol 2013; 162:98-106.
9. Rubin CM, Mick R, Johnson FL. Bone marrow transplantation for the treatment of haematological disorders in Down's syndrome: Toxicity and outcome. Bone Marrow Transplant 1996; 18:533-540.
10. Hitzler JK, He W, Doyle J, et al. Outcome of transplantation for acute myelogenous leukemia in children with Down syndrome. Biol Blood Marrow Transplant 2013; 19:893-897.
11. Meissner B, Borkhardt A, Dilloo D, et al. Relapse, not regimen-related toxicity, was the major cause of treatment failure in 11 children with Down syndrome undergoing haematopoietic stem cell transplantation for acute leukaemia. Bone Marrow Transplant 2007; 40:945-949.
12. Klein J, Moeschberger M. Survival analysis: Techniques of censored and truncated data (2nd ed.). New York, NY: Springer Verlag 2003.
13. Przepiorka D, Weisdorf D, Martin P, et al. 1994 Consensus Conference on Acute GVHD Grading. Bone Marrow Transplant 1995; 15:825-828.
14. Flowers ME, Kansu E, Sullivan KM. Pathophysiology and treatment of graft-versus-host disease. Hematol Oncol Clin North Am 1999; 13:1091-1112.
15. Conter V, D'Angelo P, Rizzari C, et al. High-dose cytosine arabinoside and fractionated total body irradiation as a preparative regimen for the treatment of children with acute lymphoblastic leukemia and Down syndrome by allogeneic bone marrow transplantation. Bone Marrow Transplant 1996; 17:287-289.
16. Goleta-Dy A, Dalla Pozza L, Shaw PJ, et al. Acute myeloid leukaemia in patients with trisomy 21 (Down syndrome) treated by bone marrow transplantation. J Pediatr Child Health 1994; 30:275-277.
17. Takagi K, Yoshida A, Kinoshita K, et al. Unrelated donor bone marrow transplantation for acute mixed lineage (myeloid and B-lymphoid lineage) leukemia in an adult with Down syndrome. Ann Hematol 2003; 82:236-240.
18. Arenson EB, Jr. Forde MD. Bone marrow transplantation for acute leukemia and Down syndrome: Report of a successful case and results of a national survey. J Pediatr 1989; 114:69-72.