Effects of zinc deficiency and supplementation on leptin and leptin receptor expression in pregnant mice

Biological and Pharmaceutical Bulletin

Volumn 37, Issue 4, 2014, Pages 581-587

  Ueda, Hidenori ^a   Nakai, Taketo ^a   Konishi, Tatsuya ^a   Tanaka, Keiichi ^a   Sakazaki, Fumitoshi ^a   Min, Kyong Son ^a  

^a OSAKA OHTANI UNIVERSITY   (Japan)

Author keywords

Dietary zinc; Leptin; Leptin receptor; Placenta; Pregnancy

Indexed keywords

GLUCOSE; INSULIN; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; ZINC; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORTER 1; SLC2A1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FERTILITY; FETUS; FETUS WEIGHT; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; MOUSE; NONHUMAN; PLACENTA WEIGHT; PREGNANCY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPPLEMENTATION; WESTERN BLOTTING; ZINC DEFICIENCY; ADIPOSE TISSUE; ANIMAL; BIOSYNTHESIS; BLOOD; DEFICIENCY; DIET SUPPLEMENTATION; DIET THERAPY; DRUG EFFECTS; FETUS DEVELOPMENT; GENE EXPRESSION; METABOLISM; NUTRITIONAL DEFICIENCY; ORGAN SIZE; PATHOLOGY; PLACENTA;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; DEFICIENCY DISEASES; DIETARY SUPPLEMENTS; FEMALE; FETAL DEVELOPMENT; GENE EXPRESSION; GLUCOSE TRANSPORTER TYPE 1; INSULIN; LEPTIN; MICE; ORGAN SIZE; PLACENTA; PREGNANCY; RECEPTORS, LEPTIN; ZINC;

EID: 84898768401     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00813     Document Type: Article

References (46)

1. Trujillo ML, Spuch C, Carro E, Señarís R. Hyperphagia and central mechanisms for leptin resistance during pregnancy. Endocrinology, 152, 1355-1365 (2011).
2. Laplante MA, Monassier L, Freund M, Bousquet P, Gachet C. The purinergic P2Y1 receptor supports leptin secretion in adipose tissue. Endocrinology, 151, 2060-2070 (2010).
3. Sagawa N, Yura S, Itoh H, Mise H, Kakui K, Korita D, Takemura M, Nuamah MA, Ogawa Y, Masuzaki H, Nakao K, Fujii S. Role of leptin in pregnancy - a review. Placenta, 23 (Suppl. A), 80-86 (2002).
4. Magariños MP, Sánchez-Margalet V, Kotler M, Calvo JC, Varone CL. Leptin promotes cell proliferation and survival of trophoblastic cells. Biol. Reprod., 76, 203-210 (2007).
5. Masuzaki H, Ogawa Y, Sagawa N, Hosoda K, Matsumoto T, Mise H, Nishimura H, Yoshimasa Y, Tanaka I, Mori T, Nakao K. Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat. Med., 3, 1029-1033 (1997).
6. Gavrilova O, Barr V, Marcus-Samuels B, Reitman M. Hyperleptinemia of pregnancy associated with the appearance of a circulating form of the leptin receptor. J. Biol. Chem., 272, 30546-30551 (1997).
7. Yamaguchi M, Murakami T, Yasui Y, Otani S, Kawai M, Kishi K, Kurachi H, Shima K, Aono T, Murata Y. Mouse placental cells secrete soluble leptin receptor (sOB-R): cAMP inhibits sOB-R production. Biochem. Biophys. Res. Commun., 252, 363-367 (1998).
8. Murakami T, Otani S, Honjoh T, Doi T, Shima K. Influence of the presence of OB-Re on leptin radioimmunoassay. J. Endocrinol., 168, 79-86 (2001).
9. Malik NM, Carter ND, Wilson CA, Scaramuzzi RJ, Stock MJ, Murray JF. Leptin expression in the fetus and placenta during mouse pregnancy. Placenta, 26, 47-52 (2005).
10. Sagawa N, Yura S, Itoh H, Kakui K, Takemura M, Nuamah MA, Ogawa Y, Masuzaki H, Nakao K, Fujii S. Possible role of placental leptin in pregnancy. Endocrine, 19, 65-71 (2002).
11. Vallee BL, Falchuk KH. The biochemical basis of zinc physiology. Physiol. Rev., 73, 79-118 (1993).
12. McCall KA, Huang C, Fierke CA. Function and mechanism of zinc metalloenzymes. J. Nutr., 130 (Suppl.), 1437S-1446S (2000).
13. Jou MY, Philipps AF, Lönnerdal B. Maternal zinc deficiency in rats affects growth and glucose metabolism in the offspring by inducing insulin resistance postnattaly. J. Nutr., 140, 1621-1627 (2010).
14. Andrews GK, Wang H, Dey SK, Palmiter RD. Mouse zinc transporter 1 gene provides an essential function during early embryonic development. Genesis, 40, 74-81 (2004).
15. Liuzzi JP, Bobo JA, Cui L, McMahon RJ, Cousins RJ. Zinc transporters 1, 2 and 4 are differentially expressed and localized in rats during pregnancy and lactation. J. Nutr., 133, 342-351 (2003).
16. Kelleher SL, McCormick NH, Velasquez V, Lopez V. Zinc in specialized secretory tissues: roles in the pancreas, prostate, and mammary gland. Adv. Nutr., 2, 101-111 (2011).
17. Kadowaki S, Munekane M, Kitamura Y, Hiromura M, Kamino S, Yoshikawa Y, Saji H, Enomoto S. Development of new zinc dithiosemicarbazone complex for use as oral antidiabetic agent. Biol. Trace Elem. Res., 154, 111-119 (2013).
18. Chen MD, Song YM, Lin PY. Zinc effects on hyperglycemia and hypoleptinemia in streptozotocin-induced diabetic mice. Horm. Metab. Res., 32, 107-109 (2000).
19. Chen MD, Song YM, Lin PY. Zinc may be a mediator of leptin production in humans. Life Sci., 66, 2143-2149 (2000).
20. Mantzoros CS, Prasad AS, Beck FW, Grabowski S, Kaplan J, Adair C, Brewer GJ. Zinc may regulate serum leptin concentrations in humans. J. Am. Coll. Nutr., 17, 270-275 (1998).
21. Sun D, Zhang L, Wang Y, Wang X, Hu X, Cui FA, Kong F. Regulation of zinc transporters by dietary zinc supplement in breast cancer. Mol. Biol. Rep., 34, 241-247 (2007).
22. Helston RM, Phillips SR, McKay JA, Jackson KA, Mathers JC, Ford D. Zinc transporters in the mouse placenta show a coordinated regulatory response to changes in dietary zinc intake. Placenta, 28, 437-444 (2007).
23. Wong CP, Song Y, Elias VD, Magnusson KR, Ho E. Zinc supplementation increases zinc status and thymopoiesis in aged mice. J. Nutr., 139, 1393-1397 (2009).
24. Summers BL, Rofe AM, Coyle P. Dietary zinc supplementation throughout pregnancy protects against fetal dysmorphology and improves postnatal survival after prenatal ethanol exposure in mice. Alcohol. Clin. Exp. Res., 33, 591-600 (2009).
25. Dempsey C, McCormick NH, Croxford TP, Seo YA, Grider A, Kelleher SL. Marginal maternal zinc deficiency in lactating mice reduces secretory capacity and alters milk composition. J. Nutr., 142, 655-660 (2012).
26. Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG, Lee JI, Friedman JM. Abnormal splicing of the leptin receptor in diabetic mice. Nature, 379, 632-635 (1996).
27. Shen XH, Han YJ, Yang BC, Cui XS, Kim NH. Hyperglycemia reduces mitochondrial content and glucose transporter expression in mouse embryos developing in vitro. J. Reprod. Dev., 55, 534-541 (2009).
28. Schulz LC, Schlitt JM, Caesar G, Pennington KA. Leptin and the placental response to maternal food restriction during early pregnancy in mice. Biol. Reprod., 87, 120 (2012).
29. Kamei Y, Tsutsumi O, Yamakawa A, Oka Y, Taketani Y, Imaki J. Maternal epidermal growth factor deficiency causes fetal hypoglycemia and intrauterine growth retardation in mice: possible involvement of placental glucose transporter GLUT3 expression. Endocrinology, 140, 4236-4243 (1999).
30. Jones HN, Woollett LA, Barbour N, Prasad PD, Powell TL, Jansson T. High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice. FASEB J., 23, 271-278 (2009).
31. Abbud W, Habinowski S, Zhang JZ, Kendrew J, Elkairi FS, Kemp BE, Witters LA, Ismail-Beigi F. Stimulation of AMP-activated protein kinase (AMPK) is associated with enhancement of Glut1-mediated glucose transport. Arch. Biochem. Biophys., 380, 347-352 (2000).
32. Zhu MJ, Du M, Nijland MJ, Nathanielsz PW, Hess BW, Moss GE, Ford SP. Down-regulation of growth signaling pathways linked to a reduced cotyledonary vascularity in placentomes of over-nourished, obese pregnant ewes. Placenta, 30, 405-410 (2009).
33. Lim CT, Kola B, Korbonits M. AMPK as a mediator of hormonal signalling. J. Mol. Endocrinol., 44, 87-97 (2010).
34. Ma Y, Zhu MJ, Uthlaut AB, Nijland MJ, Nathanielsz PW, Hess BW, Ford SP. Upregulation of growth signaling and nutrient transporters in cotyledons of early to mid-gestational nutrient restricted ewes. Placenta, 32, 255-263 (2011).
35. Tomimatsu T, Yamaguchi M, Murakami T, Ogura K, Sakata M, Mitsuda N, Kanzaki T, Kurachi H, Irahara M, Miyake A, Shima K, Aono T, Murata Y. Increase of mouse leptin production by adipose tissue after midpregnancy: gestational profile of serum leptin concentration. Biochem. Biophys. Res. Commun., 240, 213-215 (1997).
36. Kronfeld-Schor N, Zhao J, Silvia BA, Bicer E, Mathews PT, Urban R, Zimmerman S, Kunz TH, Widmaier EP. Steroid-dependent up-regulation of adipose leptin secretion in vitro during pregnancy in mice. Biol. Reprod., 63, 274-280 (2000).
37. Yura S, Sagawa N, Mise H, Mori T, Masuzaki H, Ogawa Y, Nakao K. A positive umbilical venous-arterial difference of leptin level and its rapid decline after birth. Am. J. Obstet. Gynecol., 178, 926-930 (1998).
38. Jaquet D, Leger J, Tabone MD, Czernichow P, Levy-Marchal C. High serum leptin concentrations during catch-up growth of children born with intrauterine growth retardation. J. Clin. Endocrinol. Metab., 84, 1949-1953 (1999).
39. Brenseke B, Prater MR, Bahamonde J, Gutierrez JC. Current thoughts on maternal nutrition and fetal programming of the metabolic syndrome. J. Pregnancy, 2013, 368461 (2013).
40. Inadera H. Developmental origins of obesity and type 2 diabetes: molecular aspects and role of chemicals. Environ. Health Prev. Med., 18, 185-197 (2013).
41. Gabory A, Ferry L, Fajardy I, Jouneau L, Gothié JD, Vigé A, Fleur C, Mayeur S, Gallou-Kabani C, Gross MS, Attig L, Vambergue A, Lesage J, Reusens B, Vieau D, Remacle C, Jais JP, Junien C. Maternal diets trigger sex-specific divergent trajectories of gene expression and epigenetic systems in mouse placenta. PLoS One, 7, e47986 (2012).
42. Barker DJ, Osmond C. Infant mortality, childhood nutrition, and ischaemic heart disease in England and Wales. Lancet, 327, 1077-1081 (1986).
43. Barker DJ. The origins of the developmental origins theory. J. Intern. Med., 261, 412-417 (2007).
44. Tamashiro KL, Moran TH. Perinatal environment and its influences on metabolic programming of offspring. Physiol. Behav., 100, 560-566 (2010).
45. Singhal A, Farooqi IS, O'Rahilly S, Cole TJ, Fewtrell M, Lucas A. Early nutrition and leptin concentrations in later life. Am. J. Clin. Nutr., 75, 993-999 (2002).
46. Yura S, Itoh H, Sagawa N, Yamamoto H, Masuzaki H, Nakao K, Kawamura M, Takemura M, Kakui K, Ogawa Y, Fujii S. Role of premature leptin surge in obesity resulting from intrauterine undernutrition. Cell Metab., 1, 371-378 (2005).