Preventable proportion of severe infections acquired in intensive care units: Case-mix adjusted estimations from patient-based surveillance data

Infection Control and Hospital Epidemiology

Volumn 35, Issue 5, 2014, Pages 494-501

  Lambert, Marie Laurence ^a   Silversmit, Geert ^b   Savey, Anne ^c   Palomar, Mercedes ^d,e   Hiesmayr, Michael ^f   Agodi, Antonella ^g   Van Rompaye, Bart ^b   Mertens, Karl ^a   Vansteelandt, Stijn ^b  

^a SCIENTIFIC INSTITUTE OF PUBLIC HEALTH   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c LABORATOIRE DE BIOMÉTRIE ET BIOLOGIE EVOLUTIVE   (France)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^e HOSPITAL ARNAU DE VILANOVA   (Spain)

^f MEDICAL UNIVERSITY OF VIENNA   (Austria)

^g UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; BLOODSTREAM INFECTION; CASE MIX; CATHETER INFECTION; CENTRAL VENOUS CATHETER; DISEASE SURVEILLANCE; FEMALE; HEALTHCARE ASSOCIATED INFECTION; HUMAN; INCIDENCE; INFECTION RATE; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; PROSPECTIVE STUDY; PUBLIC HEALTH SERVICE; SIMPLIFIED ACUTE PHYSIOLOGY SCORE; VENTILATOR ASSOCIATED PNEUMONIA; CROSS INFECTION; DIAGNOSIS RELATED GROUP; EPIDEMIOLOGY; EUROPE; HEALTH SURVEY; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; RISK FACTOR; SEPSIS; STANDARDS; STATISTICS AND NUMERICAL DATA;

AGED; CROSS INFECTION; DIAGNOSIS-RELATED GROUPS; EUROPE; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; POPULATION SURVEILLANCE; RISK FACTORS; SEPSIS;

EID: 84898765723     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/675824     Document Type: Article

References (30)

1. European Centre for Disease Prevention and Control (ECDC). Surveillance of health-care associated infections in Europe 2007. Stockholm, Sweden: ECDC, 2012. http://ecdc.europa.eu/en/publications/Publications/120215_SUR_HAI_2007.pdf.
2. Hunter JD. Ventilator associated pneumonia. BMJ 2012;344: e3325.
3. Rello J, Lode H, Cornaglia G, Masterton R. A European care bundle for prevention of ventilator-associated pneumonia. Intensive Care Med 2010;36(5):773-780.
4. Berenholtz SM, Pham JC, Thompson DA, et al. Collaborative cohort study of an intervention to reduce ventilator-associated pneumonia in the intensive care unit. Infect Control Hosp Epidemiol 2011;32(4):305-314.
5. Klompas M. Ventilator-associated pneumonia: is zero possible? Clin Infect Dis 2010;51(10):1123-1126.
6. Bonten MJ. Healthcare epidemiology: Ventilator-associated pneumonia: preventing the inevitable. Clin Infect Dis 2011;52(1): 115-121.
7. Umscheid CA, Mitchell MD, Doshi JA, Agarwal R, Williams K, Brennan PJ. Estimating the proportion of healthcare-associated infections that are reasonably preventable and the related mortality and costs. Infect Control Hosp Epidemiol 2011;32(2):101-114.
8. Pronovost PJ, Goeschel CA, Colantuoni E, et al. Sustaining reductions in catheter related bloodstream infections in Michigan intensive care units: observational study. BMJ 2010;340:c309.
9. Sax H, Pittet D. Interhospital differences in nosocomial infection rates: importance of case-mix adjustment. Arch Intern Med 2002; 162(21):2437-2442.
10. Hugonnet S, Chevrolet JC, Pittet D. The effect of workload on infection risk in critically ill patients. Crit Care Med 2007;35(1): 76-81.
11. Pronovost PJ, Berenholtz SM, Goeschel C et al. Improving patient safety in intensive care units in Michigan. J Crit Care 2008; 23(2):207-221.
12. Hospital in Europe Link for Infection Control through Surveillance (HELICS). Surveillance of Nosocomial Infections in Intensive Care Units Protocol 6.1. European Centre for Disease Control, 2004D/2004/2505/48. http://www.ecdc.europa.eu/en /activities/surveillance/hai/documents/0409_ipse_icu_protocol.pdf. Accessed May 5, 2013.
13. Lambert ML, Suetens C, Savey A, et al. Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study. Lancet Infect Dis 2011;11(1):30-38.
14. Centers for Disease Control and Prevention (CDC). Central line associated bloodstream infection (CLABSI) event: guidelines and procedures for monitoring CLABSI. 2011. http://www.cdc.gov/nhsn/PDFs/pscManual/4PSC_CLABScurrent.pdf. Accessed June 15, 2011.
15. Taubman SL, Robins JM, Mittleman MA, Hernan MA. Intervening on risk factors for coronary heart disease: an application of the parametric g-formula. Int J Epidemiol 2009;38(6):1599-1611.
16. Vansteelandt S, Keiding N. Invited commentary: G-computation-lost in translation? Am J Epidemiol 2011;173(7):739-742.
17. Le Gall J, Neumann A, Hemery F, et al. Mortality prediction using SAPS II: an update for French intensive care units. Critical Care 2005;9(6):R645-R652.
18. Prowle JR, Echeverri JE, Ligabo EV, et al. Acquired bloodstream infection in the intensive care unit: incidence and attributable mortality. Crit Care 2011;15(2):R100.
19. A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing, 2011.
20. Ranji SR, Shetty K, Posley KA, Lewis R, Winston LG. Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies. Vol 6, Prevention of Healthcare-Associated Infections. Rockville, MD: Agency for Healthcare Research and Quality, 2007. http://www.ahrq.gov/downloads/pub/evidence/pdf/qualgap6/hainfgap.pdf. Accessed June 15, 2013
21. Klompas M. Is a ventilator-associated pneumonia rate of zero really possible? Curr Opin Infect Dis 2012;25(2):176-182.
22. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36(5):309-332.
23. Haley RW, Culver DH, White JW, et al. The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals. Am J Epidemiol 1985;121(2):182-205.
24. Gastmeier P, Geffers C, Brandt C, et al. Effectiveness of a nationwide nosocomial infection surveillance system for reducing nosocomial infections. J Hosp Infect 2006;64(1):16-22.
25. Piantadosi S, Byar DP, Green SB. The ecological fallacy. Am J Epidemiol 1988;127(5):893-904.
26. Wolkewitz M, Vonberg RP, Grundmann H, et al. Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks models. Crit Care 2008;12(2):R44.
27. Lipitz-Snyderman A, Needham DM, Colantuoni E, et al. The ability of intensive care units to maintain zero central line-associated bloodstream infections. Arch Intern Med 2011;171(9): 856-858.
28. Harbarth S, Sax H, Gastmeier P. The preventable proportion of nosocomial infections: an overview of published reports. J Hosp Infect 2003;54(4):258-266.
29. Gastmeier P, Geffers C. Prevention of ventilator-associated pneumonia: analysis of studies published since 2004. J Hosp Infect 2007;67(1):1-8.
30. Centers for Disease Control and Prevention. National and state healthcare-associated infections standardized infection ratio report, January 2010-December 2010. 2011. http://www.cdc.gov/hai/national-sir-jan-dec-2010/index.html. Accessed December 10, 2012