The preventable proportion of nosocomial infections: An overview of published reports

Journal of Hospital Infection

Volumn 54, Issue 4, 2003, Pages 258-266

  Harbarth, Stephan ^a   Sax, H ^a   Gastmeier, P ^b  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Cross transmission; Hospital; Infection; Intervention; Preventability; Reduction

Indexed keywords

BACTEREMIA; CATHETER INFECTION; CLINICAL PRACTICE; COST EFFECTIVENESS ANALYSIS; CROSS INFECTION; DISEASE TRANSMISSION; HOSPITAL INFECTION; HUMAN; INFECTION RISK; INTENSIVE CARE UNIT; MEDICAL RESEARCH; PUBLISHING; RETROSPECTIVE STUDY; REVIEW; SURGICAL WARD; WORK ENVIRONMENT; ARTICLE; CLINICAL TRIAL; COST BENEFIT ANALYSIS; FEASIBILITY STUDY; HEALTH CARE QUALITY; INDWELLING CATHETER; INFECTION CONTROL; INTERVENTION STUDY; META ANALYSIS; METHODOLOGY; ORGANIZATION AND MANAGEMENT; RISK FACTOR;

BACTEREMIA; CATHETERS, INDWELLING; COST-BENEFIT ANALYSIS; CROSS INFECTION; DISEASE TRANSMISSION, HORIZONTAL; FEASIBILITY STUDIES; HUMANS; INFECTION CONTROL; INTERVENTION STUDIES; PROGRAM EVALUATION; RESEARCH DESIGN; RISK FACTORS;

EID: 0347906291     PISSN: 01956701     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0195-6701(03)00150-6     Document Type: Review

References (68)

1. Gerberding J.L. Hospital-onset infections: a patient safety issue Ann Intern Med 137 2002 665-670
2. Kurz A. Sessler D.I. Lenhardt R. Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization N Engl J Med 334 1996 1209-1215
3. Perl T.M. Cullen J.J. Wenzel R.P. et-al. Intranasal mupirocin to prevent postoperative Staphylococcus aureus infections N Engl J Med 346 2002 1871-1877
4. Krueger W.A. Unertl K.E. Selective decontamination of the digestive tract Curr Opin Crit Care 8 2002 139-144
5. Harbarth S. Pittet D. Grady L. et-al. Interventional study to evaluate the impact of an alcohol-based hand gel in improving hand hygiene compliance Pediatr Infect Dis J 21 2002 489-495
6. Haley R.W. Culver D.H. White J.W. The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals Am J Epidemiol 121 1985 182-205
7. Emmerson A.M. The impact of surveys on hospital infection J Hosp Infect 30 Suppl. 1995 421-440
8. Danchaivijitr S. Tangtrakool T. Waitayapiches S. Chokloikaew S. Efficacy of hospital infection control in Thailand 1988-1992 J Hosp Infect 32 1996 147-153
9. Vaque J. Rossello J. Arribas J.L. Prevalence of nosocomial infections in Spain: EPINE study 1990-1997. EPINE Working Group J Hosp Infect 43 Suppl. 1999 S105-S111
10. Gikas A. Pediaditis I. Roumbelaki M. Troulakis G. Romanos J. Tselentis Y. Repeated multi-centre prevalence surveys of hospital-acquired infection in Greek hospitals. Cretan Infection Control Network J Hosp Infect 41 1999 11-18
11. Andersen B.M. Ringertz S.H. Gullord T.P. et-al. A three-year survey of nosocomial and community-acquired infections, antibiotic treatment and re-hospitalization in a Norwegian health region J Hosp Infect 44 2000 214-223
12. Christensen M. Jepsen O.B. Reduced rates of hospital-acquired UTI in medical patients. Prevalence surveys indicate effect of active infection control programmes J Hosp Infect 47 2001 36-40
13. Sax H. Pittet D. Interhospital differences in nosocomial infection rates: importance of case-mix adjustment Arch Intern Med 162 2002 2437-2442
14. Pittet D. Hugonnet S. Harbarth S. et-al. Effectiveness of a hospital-wide programme to improve compliance with hand hygiene Lancet 356 2000 1307-1312
15. Eggimann P. Harbarth S. Constantin M.N. Touveneau S. Chevrolet J.C. Pittet D. Impact of a prevention strategy targeted at vascular-access care on incidence of infections acquired in intensive care Lancet 355 2000 1864-1868
16. Makris A.T. Morgan L. Gaber D.J. Richter A. Rubino J.R. Effect of a comprehensive infection control program on the incidence of infections in long-term care facilities Am J Infect Control 28 2000 3-7
17. Harbarth S. Sudre P. Dharan S. Cadenas M. Pittet D. Outbreak of Enterobacter cloacae related to understaffing, overcrowding, and poor hygiene practices Infect Control Hosp Epidemiol 20 1999 598-603
18. Bischoff W.E. Reynolds T.M. Sessler C.N. Edmond M.B. Wenzel R.P. Handwashing compliance by healthcare workers: the impact of introducing an accessible, alcohol-based hand antiseptic Arch Intern Med 160 2000 1017-1021
19. Sherertz R.J. Ely E.W. Westbrook D.M. et-al. Education of physicians-in-training can decrease the risk for vascular catheter infection Ann Intern Med 132 2000 641-648
20. Weinberg M. Fuentes J.M. Ruiz A.I. et-al. Reducing infections among women undergoing cesarean section in Colombia by means of continuous quality improvement methods Arch Intern Med 161 2001 2357-2365
21. Harbarth S. Dharan S. Liassine N. Herrault P. Auckenthaler R. Pittet D. Randomized, placebo-controlled, double-blind trial to evaluate the efficacy of mupirocin for eradicating carriage of methicillin-resistant Staphylococcus aureus Antimicrob Agents Chemother 43 1999 1412-1416
22. Darouiche R.O. Raad I.I. Heard S.O. et-al. A comparison of two antimicrobial-impregnated central venous catheters N Engl J Med 340 1999 1-8
23. Bonten M.J. Hayden M.K. Nathan C. et-al. Epidemiology of colonisation of patients and environment with vancomycin-resistant enterococci Lancet 348 1996 1615-1619
24. Bergmans D.C. Bonten M.J. van Tiel F.H. et-al. Cross-colonisation with Pseudomonas aeruginosa of patients in an intensive care unit Thorax 53 1998 1053-1058
25. Bonten M.J. Bergmans D.C. Speijer H. Stobberingh E.E. Characteristics of polyclonal endemicity of Pseudomonas aeruginosa colonization in intensive care units. Implications for infection control Am J Respir Crit Care Med 160 1999 1212-1219
26. Bertrand X. Thouverez M. Talon D. et-al. Endemicity, molecular diversity and colonisation routes of Pseudomonas aeruginosa in intensive care units Intensive Care Med 27 2001 1263-1268
27. Michaud S. Suzuki S. Harbarth S. Effect of design-related bias in studies of diagnostic tests for ventilator-associated pneumonia Am J Respir Crit Care Med 166 2002 1320-1325
28. Harbarth S. Cosgrove S. Carmeli Y. Effects of antibiotics on nosocomial epidemiology of vancomycin-resistant enterococci Antimicrob Agents Chemother 46 2002 1619-1628
29. Veenstra D.L. Saint S. Saha S. Lumley T. Sullivan S.D. Efficacy of antiseptic-impregnated central venous catheters in preventing catheter-related bloodstream infection: a meta-analysis JAMA 281 1999 261-267
30. Marin M.G. Lee J.C. Skurnick J.H. Prevention of nosocomial bloodstream infections: effectiveness of antimicrobial-impregnated and heparin-bonded central venous catheters Crit Care Med 28 2000 3332-3338
31. Walder B. Pittet D. Tramer M.R. Prevention of bloodstream infections with central venous catheters treated with anti-infective agents depends on catheter type and insertion time: evidence from a meta-analysis Infect Control Hosp Epidemiol 23 2002 748-756
32. Greco D. Moro M.L. Tozzi A.E. De Giacomi G.V. Effectiveness of an intervention program in reducing postoperative infections. Italian PRINOS Study Group Am J Med 91 1991 164S-169S
33. Raine S.J. Quality assurance and the role of infection control: a retrospective study of hospital-acquired infection in a District General Hospital based on three sites, 1978-1988 J Hosp Infect 19 1991 49-61
34. Evaldson G.R. Frederici H. Jullig C. Mannerquist K. Nystrom B. Hospital-associated infections in obstetrics and gynecology. Effects of surveillance Acta Obstet Gynecol Scand 71 1992 54-58
35. Malone N. Larson E. Factors associated with a significant reduction in hospital-wide infection rates Am J Infect Control 24 1996 180-185
36. Ng S.P. Gomez J.M. Lim S.H. Ho N.K. Reduction of nosocomial infection in a neonatal intensive care unit (NICU) Singapore Med J 39 1998 319-323
37. Hacek D.M. Suriano T. Noskin G.A. Kruszynski J. Reisberg B. Peterson L.R. Medical and economic benefit of a comprehensive infection control program that includes routine determination of microbial clonality Am J Clin Pathol 111 1999 647-654
38. Delgado-Rodriguez M. Gomez-Ortega A. Sillero-Arenas M. Martinez-Gallego G. Medina-Cuadros M. Llorca J. Efficacy of surveillance in nosocomial infection control in a surgical service Am J Infect Control 29 2001 289-294
39. Gastmeier P. Brauer H. Forster D. Dietz E. Daschner F. Ruden H. A quality management project in 8 selected hospitals to reduce nosocomial infections: a prospective, controlled study Infect Control Hosp Epidemiol 23 2002 91-97
40. Kelleghan S.I. Salemi C. Padilla S. et-al. An effective continuous quality improvement approach to the prevention of ventilator-associated pneumonia Am J Infect Control 21 1993 322-330
41. Berg D.E. Hershow R.C. Ramirez C.A. Weinstein R.A. Control of nosocomial infections in an intensive care unit in Guatemala City Clin Infect Dis 21 1995 588-593
42. Joiner G.A. Salisbury D. Bollin G.E. Utilizing quality assurance as a tool for reducing the risk of nosocomial ventilator-associated pneumonia Am J Med Qual 11 1996 100-103
43. Civetta J.M. Hudson-Civetta J. Ball S. Decreasing catheter-related infection and hospital costs by continuous quality improvement Crit Care Med 24 1996 1660-1665
44. Cohran J. Larson E. Roach H. Blane C. Pierce P. Effect of intravascular surveillance and education program on rates of nosocomial bloodstream infections Heart Lung 25 1996 161-164
45. Maas A. Flament P. Pardou A. Deplano A. Dramaix M. Struelens M.J. Central venous catheter-related bacteraemia in critically ill neonates: risk factors and impact of a prevention programme J Hosp Infect 40 1998 211-224
46. Bishop-Kurylo D. The clinical experience of continuous quality improvement in the neonatal intensive care unit J Perinat Neonatal Nurs 12 1998 51-57
47. Dumigan D.G. Kohan C.A. Reed C.R. Jekel J.F. Fikrig M.K. Utilizing national nosocomial infection surveillance system data to improve urinary tract infection rates in three intensive-care units Clin Perform Qual Health Care 6 1998 172-178
48. Goetz A.M. Kedzuf S. Wagener M. Muder R.R. Feedback to nursing staff as an intervention to reduce catheter-associated urinary tract infections Am J Infect Control 27 1999 402-424
49. Bijma R. Girbes A.R. Kleijer D.J. Zwaveling J.H. Preventing central venous catheter-related infection in a surgical intensive-care unit Infect Control Hosp Epidemiol 20 1999 618-620
50. McConkey S.J. L'Ecuyer P.B. Murphy D.M. Leet T.L. Sundt T.M. Fraser V.J. Results of a comprehensive infection control program for reducing surgical-site infections in coronary artery bypass surgery Infect Control Hosp Epidemiol 20 1999 533-538
51. Kaye J. Ashline V. Erickson D. et-al. Critical care bug team: a multidisciplinary team approach to reducing ventilator-associated pneumonia Am J Infect Control 28 2000 197-201
52. Yoo S. Ha M. Choi D. Pai H. Effectiveness of surveillance of central catheter-related bloodstream infection in an ICU in Korea Infect Control Hosp Epidemiol 22 2001 433-436
53. Coopersmith C.M. Rebmann T.L. Zack J.E. et-al. Effect of an education program on decreasing catheter-related bloodstream infections in the surgical intensive care unit Crit Care Med 30 2002 59-64
54. Chetchotisakd P. Phelps C.L. Hartstein A.I. Assessment of bacterial cross-transmission as a cause of infections in patients in intensive care units Clin Infect Dis 18 1994 929-937
55. Weist K. Pollege K. Schulz I. Ruden H. Gastmeier P. How many nosocomial infections are associated with cross-transmission? A prospective cohort study in a surgical intensive care unit Infect Control Hosp Epidemiol 23 2002 127-132
56. Grundmann H. Hahn A. Ehrenstein B. Geiger K. Just Daschner F.D. Detection of cross-transmission of multiresistant Gram-negative bacilli and Staphylococcus aureus in adult intensive care units by routine typing of clinical isolates Clin Microbiol Infect 5 1999 355-363
57. Webster C.A. Towner K.J. Use of RAPD-ALF analysis for investigating the frequency of bacterial cross-transmission in an adult intensive care unit J Hosp Infect 44 2000 254-260
58. Garner J.S. Jarvis W.R. Emori T.G. Toran T.C. Hughes J.M. CDC definitions for nosocomial infections Am J Infect Control 16 1988 128-140
59. Ayliffe G.A. Nosocomial infection-the irreducible minimum Infect Control 7 Suppl. 2 1986 92-95
60. Pittet D. Eggimann P. Rubinovitch B. Prevention of ventilator-associated pneumonia by oral decontamination: just another SDD study? Am J Respir Crit Care Med 164 2001 338-339
61. Grosser J. Meyer R. Wilbrandt B. Grosse K. Uhlmann F. Investigations on the relevance and avoidability of nosocomial infections as a cause of death in hospitals Hygiene und Medizin 19 1994 132-136
62. Maki D.G. Mermel L.A. Infections due to infusion therapy Bennett J.V. Brachman P.S. Hospital Infections 4th edn 1998 689-724 Lippincott-Raven Philadelphia, PA
63. Eggimann P. Pittet D. Overview of catheter-related infections with special emphasis on prevention based on educational programs Clin Microbiol Infect 8 2002 295-309
64. Murray C.J. Lopez A.D. On the comparable quantification of health risks: lessons from the Global Burden of Disease Study Epidemiology 10 1999 594-605
65. Aavitsland P. Stormark M. Lystad A. Hospital-acquired infections in Norway: a national prevalence survey in 1991 Scand J Infect Dis 24 1992 477-483
66. Wilson A.P. Bint A.J. Glenny A.M. Leibovici L. Peto T.E. Meta-analysis and systematic review of antibiotic trials J Hosp Infect 43 Suppl. 1999 S211-S214
67. Poulsen K.B. Jepsen O.B. Failure to detect a general reduction of surgical wound infections in Danish hospitals Dan Med Bull 42 1995 485-488
68. Sterne J.A. Egger M. Smith G.D. Systematic reviews in health care: investigating and dealing with publication and other biases in meta-analysis BMJ 323 2001 101-105