The discovery of angiogenic growth factors: The contribution of Italian scientists

Vascular Cell

Volumn 6, Issue 1, 2014, Pages

  Ribatti, Domenico ^a,b  

^a UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^b NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

Author keywords

Angiogenesis; EPO; FGF 2; G CSF; GM CSF; PlGF; VEGF

Indexed keywords

BEVACIZUMAB; ERYTHROPOIETIN; FIBROBLAST GROWTH FACTOR 2; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PLACENTAL GROWTH FACTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1;

AMINO ACID SEQUENCE; ANGIOGENESIS; BIOLOGICAL ACTIVITY; CARTILAGE CELL; CELL PROLIFERATION; DRUG DEVELOPMENT; ENDOTHELIUM CELL; ERYTHROPOIESIS; FIBROBLAST; HUMAN; IN VITRO STUDY; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ISOLATION; REVIEW; SCIENTIST; TROPHOBLAST; TUMOR CELL LINE;

EID: 84898761509     PISSN: None     EISSN: 2045824X     Source Type: Journal    
DOI: 10.1186/2045-824X-6-8     Document Type: Review

References (50)

1. Vascular reactions of normal and malignant tissue in vivo. Algire GH, Chalkley HW, J Natl Cancer Inst 1945 6 73 85
2. Isolation of a tumor factor responsible for angiogenesis. Folkman J, Merler E, Abernathy C, Williams G, J Exp Med 1971 133 275 288 10.1084/jem.133.2.275 4332371
3. Pituitary extracts and steroid hormones in the control of 3T3 cell growth. Armelin HA, Proc Natl Acad Sci U S A 1973 70 2702 2706 10.1073/pnas.70.9.2702 4354860
4. Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth. Gospodarowicz D, Nature 1974 249 123 127 10.1038/249123a0 4364816
5. Purification of a fibroblast growth factor from bovine pituitary. Gospodarowicz D, J Biol Chem 1975 250 2515 2520 1168187
6. Purification of the fibroblast growth factor activity from bovine brain. Gospodarowicz D, Bialecki H, Greenburg G, J Biol Chem 1978 253 3736 3743 649600 (Pubitemid 8346572)
7. Heparin affinity: purification of a tumor-derived capillary endothelial cell growth factor. Shing Y, Folkman J, Sullivan R, Butterfield C, Murray J, Klagsbrun M, Science 1984 223 1296 1299 10.1126/science.6199844 6199844 (Pubitemid 14163183)
8. Angiogenesis is stimulated by a tumor-derived endothelial cell growth factor. Shing Y, Folkman J, Haudenschild C, Lund D, Crum R, Klagsbrun M, J Cell Biochem 1985 29 275 287 10.1002/jcb.240290402 2418039 (Pubitemid 16173421)
9. Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Esch F, Baird A, Ling N, Ueno N, Hill F, Denoroy L, Klepper R, Gospodarowicz D, Bohlen P, Guillemin R, Proc Natl Acad Sci U S A 1985 82 6507 6511 10.1073/pnas.82.19.6507 3863109 (Pubitemid 16230543)
10. Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor. Gospodarowicz D, Cheng J, Lui GM, Baird A, Bohlent P, Proc Natl Acad Sci U S A 1984 81 6963 6967 10.1073/pnas.81.22.6963 6594674 (Pubitemid 15216678)
11. Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis, and migration. Moscatelli D, Presta M, Rifkin DB, Proc Natl Acad Sci U S A 1986 83 2091 2095 10.1073/pnas.83.7.2091 3008151 (Pubitemid 16020840)
12. Purification from a human hepatoma cell line of a basic fibroblast growth factor-like molecule that stimulates capillary endothelial cell plasminogen activator production, DNA synthesis, and migration. Presta M, Moscatelli D, Joseph-Silverstein J, Rifkin DB, Mol Cell Biol 1986 6 4060 4066 3025628
13. Transport epithelial characteristics of cultured bovine pituitary follicular cells. Ferrara N, Fujii DK, Goldsmith PC, Widdicombe JH, Weiner RI, Am J Physiol 1987 252 304 E312 2881486
14. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Ferrara N, Henzel WJ, Biochem Biophys Res Commun 1989 161 851 858 10.1016/0006-291X(89)92678-8 2735925 (Pubitemid 19162712)
15. Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea-pigs. Miles AA, Miles EM, J Physiol 1952 118 228 257 13000707
16. Induction of a fibrin-gel investment: an early event in line 10 hepatocarcinoma growth mediated by tumor-secreted products. Dvorak HF, Orenstein NS, Carvalho AC, Churchill WH, Dvorak AM, Galli SJ, Feder J, Bitzer AM, Rypysc J, Giovinco P, J Immunol 1979 122 166 174 762415 (Pubitemid 9078536)
17. Vascular permeability factor, fibrin, and the pathogenesis of tumor stroma formation. Dvorak HF, Nagy JA, Berse B, Brown LF, Yeo KT, Yeo TK, Dvorak AM, van de Water L, Sioussat TM, Senger DR, Ann N Y Acad Sci 1992 667 101 111 10.1111/j.1749-6632.1992.tb51603.x 1309029 (Pubitemid 23061569)
18. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF, Science 1983 219 983 985 10.1126/science.6823562 6823562
19. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT, Science 1992 255 989 991 10.1126/science.1312256 1312256
20. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. Gerber HP, Condorelli F, Park J, Ferrara N, J Biol Chem 1997 272 23659 23667 10.1074/jbc.272.38.23659 9295307 (Pubitemid 27410939)
21. Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. Park JE, Chen HH, Winer J, Houck KA, Ferrara N, J Biol Chem 1994 269 25646 25654 7929268
22. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, O'Shea KS, Powell-Braxton L, Hillan KJ, Moore MW, Nature 1996 380 439 442 10.1038/380439a0 8602242 (Pubitemid 26102720)
23. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A, Nature 1996 380 435 439 10.1038/380435a0 8602241 (Pubitemid 26102719)
24. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS, Ferrara N, Nature 1993 362 841 844 10.1038/362841a0 7683111 (Pubitemid 23132159)
25. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Presta LG, Chen H, O'Connor SJ, Chisholm V, Meng YG, Krummen L, Winkler M, Ferrara N, Cancer Res 1997 57 4593 4599 9377574 (Pubitemid 27441066)
26. Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ferrrara N, Nature 2007 450 825 831 10.1038/nature06348 18064003 (Pubitemid 350231321)
27. The crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolution. Iyer S, Leonidas DD, Swaminathan GJ, Maglione D, Battisti M, Tucci M, Persico MG, Acharya KR, J Biol Chem 2001 276 12153 12161 10.1074/jbc.M008055200 11069911
28. Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. Maglione D, Guerriero V, Viglietto G, Delli-Bovi P, Persico MG, Proc Natl Acad Sci U S A 1991 88 9267 9271 10.1073/pnas.88.20. 9267 1924389 (Pubitemid 21915612)
29. Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14. Maglione D, Guerriero V, Viglietto G, Ferraro MG, Aprelikova O, Alitalo K, Del Vecchio S, Lei KJ, Chou JY, Persico MG, Oncogene 1993 8 925 931 7681160 (Pubitemid 23087424)
30. Localisation of placenta growth factor (PIGF) in human term placenta. Khaliq A, Li XF, Shams M, Sisi P, Acevedo CA, Whittle MJ, Weich H, Ahmed A, Growth Factors 1996 13 243 250 10.3109/08977199609003225 8919031 (Pubitemid 26378943)
31. Expression of vascular endothelial growth factor and placenta growth factor in human placenta. Vuorela P, Hatva E, Lymboussaki A, Kaipainen A, Joukov V, Persico MG, Alitalo K, Halmesmaki E, Biol Reprod 1997 56 489 494 10.1095/biolreprod56.2.489 9116151 (Pubitemid 27081593)
32. Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic. Ziche M, Maglione D, Ribatti D, Morbidelli L, Lago CT, Battisti M, Paoletti I, Barra A, Tucci M, Parise G, Vincenti V, Granger HJ, Viglietto G, Persico MG, Lab Invest 1997 76 517 531 9111514 (Pubitemid 27176106)
33. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Carmeliet P, Moons L, Luttun A, Vincenti V, Compernolle V, De Mol M, Wu Y, Bono F, Devy L, Beck H, Scholz D, Acker T, Di Palma T, Dewerchin M, Noel A, Stalmans I, Barra A, Blacher S, VandenDriessche T, Ponten A, Eriksson U, Plate KH, Foidart JM, Schaper W, Charnock-Jones DS, Hicklin DJ, Herbert JM, Collen D, Persico MG, Nat Med 2001 7 575 583 10.1038/87904 11329059 (Pubitemid 32448325)
34. PlGF blockade does not inhibit angiogenesis during primary tumor growth. Bais C, Wu X, Yao J, Yang S, Crawford Y, McCutcheon K, Tan C, Kolumam G, Vernes JM, Eastham-Anderson J, Haughney P, Kowanetz M, Hagenbeek T, Kasman I, Reslan HB, Ross J, Van Bruggen N, Carano RA, Meng YJ, Hongo JA, Stephan JP, Shibuya M, Ferrara N, Cell 2010 141 166 177 10.1016/j.cell.2010.01.033 20371352
35. Proliferative and migratory responses of murine microvascular endothelial cells to granulocyte-colony-stimulating factor. Bocchietto E, Guglielmetti A, Silvagno F, Taraboletti G, Pescarmona GP, Mantovani A, Bussolino F, J Cell Physiol 1993 155 89 95 10.1002/jcp.1041550112 7682223 (Pubitemid 23109060)
36. Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. Bussolino F, Wang JM, Defilippi P, Turrini F, Sanavio F, Edgell CJ, Aglietta M, Arese P, Mantovani A, Nature 1989 337 471 473 10.1038/337471a0 2464767 (Pubitemid 19047464)
37. Differential expression of the common beta and specific alpha chains of the receptors for GM-CSF, IL-3, and IL-5 in endothelial cells. Colotta F, Bussolino F, Polentarutti N, Guglielmetti A, Sironi M, Bocchietto E, De Rossi M, Mantovani A, Exp Cell Res 1993 206 311 317 10.1006/excr.1993.1151 7684696 (Pubitemid 23212949)
38. Enhancement of plasminogen activator activity in cultured endothelial cells by granulocyte colony-stimulating factor. Kojima S, Tadenuma H, Inada Y, Saito Y, J Cell Physiol 1989 138 192 196 10.1002/jcp.1041380125 2463258 (Pubitemid 19038687)
39. Activation of JAK2 in human vascular endothelial cells by granulocyte-macrophage colony-stimulating factor. Soldi R, Primo L, Brizzi MF, Sanavio F, Aglietta M, Polentarutti N, Pegoraro L, Mantovani A, Bussolino F, Blood 1997 89 863 872 9028317 (Pubitemid 27121279)
40. In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF. Valdembri D, Serini G, Vacca A, Ribatti D, Bussolino F, FASEB J 2002 16 225 227 11744626
41. In vitro and in vivo activation of endothelial cells by colony-stimulating factors. Bussolino F, Ziche M, Wang JM, Alessi D, Morbidelli L, Cremona O, Bosia A, Marchisio PC, Mantovani A, J Clin Invest 1991 87 986 995 10.1172/JCI115107 1705569
42. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. Bussolino F, Di Renzo MF, Ziche M, Bocchietto E, Olivero M, Naldini L, Gaudino G, Tamagnone L, Coffer A, Comoglio PM, J Cell Biol 1992 119 629 641 10.1083/jcb.119.3.629 1383237
43. Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer. Tamagnone L, Cancer Cell 2012 22 145 152 10.1016/j.ccr.2012.06.031 22897846
44. Semaphorin 6A regulates angiogenesis by modulating VEGF signaling. Segarra M, Ohnuki H, Maric D, Salvucci O, Hou X, Kumar A, Li X, Tosato G, Blood 2012 120 4104 4115 10.1182/blood-2012-02-410076 23007403
45. Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells. Anagnostou A, Lee ES, Kessimian N, Levinson R, Steiner M, Proc Natl Acad Sci U S A 1990 87 5978 5982 10.1073/pnas.87.15.5978 2165612 (Pubitemid 20240413)
46. Erythropoietin receptor mRNA expression in human endothelial cells. Anagnostou A, Liu Z, Steiner M, Chin K, Lee ES, Kessimian N, Noguchi CT, Proc Natl Acad Sci U S A 1994 91 3974 3978 10.1073/pnas.91.9.3974 8171022 (Pubitemid 24139555)
47. Recombinant human erythropoietin stimulates angiogenesis in vitro. Carlini RG, Reyes AA, Rothstein M, Kidney Int 1995 47 740 745 10.1038/ki.1995.113 7752572
48. Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Ribatti D, Presta M, Vacca A, Ria R, Giuliani R, Dell'Era P, Nico B, Roncali L, Dammacco F, Blood 1999 93 2627 2636 10194442 (Pubitemid 29181195)
49. The history of the angiogenic switch concept. Ribatti D, Nico B, Crivellato E, Roccaro AM, Vacca A, Leukemia 2007 21 44 52 10.1038/sj.leu.2404402 16990761 (Pubitemid 44921833)
50. Non-classic endogenous novel regulators of angiogenesis. Ribatti D, Conconi MT, Nussdorfer GG, Pharmacol Rev 2007 59 185 205 10.1124/pr.59.2.3 17540906 (Pubitemid 46855439)