A clinical biomarker assay for the quantification of d3-creatinine and creatinine using LC-MS/MS

Bioanalysis

Volumn 6, Issue 6, 2014, Pages 745-749

  Leonard, Michael ^a   Dunn, John ^a   Smith, Glenn ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; BIOLOGICAL MARKER;

ARTICLE; CONTROLLED STUDY; CREATININE URINE LEVEL; DILUTION; HUMAN; LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; URINALYSIS; VALIDATION PROCESS; MASS SPECTROMETRY; METABOLISM; PROCEDURES; URINE;

BIOLOGICAL MARKERS; CHROMATOGRAPHY, LIQUID; CREATININE; HUMANS; MASS SPECTROMETRY;

EID: 84898760581     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.13.323     Document Type: Article

References (20)

1. Selberg O, Burchert W, Graubner G, Wenner C, Ehrenheim C, Muller MJ. Determination of anatomical skeletal muscle mass by whole body nuclear magnetic resonance. Basic Life Sci. 60, 95-97 (1993).
2. Sjostrom L. A computer-tomography based multicompartment body composition technique and anthropometric predictions of lean body mass, total and subcutaneous adipose tissue. Int.J. Obes. 15(Suppl. 2), 19-30 (1991).
3. Kim J, Shen W, Gallagher D et al. Total-body skeletal muscle mass: estimation by dual-energy x-ray absorptiometry in children and adolescents. Am. J. Clin. Nutr. 84(5), 1014-1020 (2006).
4. Heymsfield SB, Arteaga C, McManus C, Smith J, Moffitt S. Measurement of muscle mass in humans: validity of the 24-hour urinary creatinine method. Am. J. Clin. Nutr. 37(3), 478-494 (1983).
5. Wang ZM, Gallagher D, Nelson ME, Matthews DE, Heymsfield SB. Total-body skeletal muscle mass: evaluation of 24-h urinary creatinine excretion by computerized axial tomography. Am. J. Clin. Nutr. 63(6), 863-869 (1996).
6. Stimpson SA, Turner SM, Clifton LG et al. Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-d3) dilution in rats. J. Appl. Physiol. 112(11), 1940-1948 (2012).
7. Stimpson S, Leonard M, Clifton L et al. Longitudinal changes in total body creatine pool size and skeletal muscle mass using the d3-creatine dilution method. J. Cachexia Sarcopenia Muscle 4(3), 217-223 (2013).
8. Kreisberg RA, Bowdoin B, Meador CK. Measurement of muscle mass in humans by isotopic dilution of creatine-14C. J. Appl. Physiol. 28(3), 264-267 (1970).
9. Park EK, Watanabe T, Gee SJ, Schenker MB, Hammock BD. Creatinine measurements in 24 h urine by liquid chromatography-tandem mass spectrometry. J. Agric. Food Chem. 56(2), 333-336 (2008).
10. Macneil L, Hill L, MacDonald D et al. Analysis of creatine, creatinine, creatine-d3 and creatinine-d3 in urine, plasma, and red blood cells by HPLC and GC-MS to follow the fate of ingested creatine-d3. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 827(2), 210-215 (2005).
11. Tsikas D, Wolf A, Mitschke A, Gutzki FM, Will W, Bader M. GC-MS determination of creatinine in human biological fluids as pentafluorobenzyl derivative in clinical studies and biomonitoring: inter-laboratory comparison in urine with Jaffe, HPLC and enzymatic assays. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 878(27), 2582-2592 (2010).
12. Yasuda M, Sugahara K, Zhang J et al. Simultaneous determination of creatinine, creatine, and guanidinoacetic acid in human serum and urine using liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. Anal. Biochem. 253(2), 231-235 (1997).
13. Jemal M, Schuster A, Whigan DB. Liquid chromatography-tandem mass spectrometry methods for quantitation of mevalonic acid in human plasma and urine: method validation, demonstration of using a surrogate analyte, and demonstration of unacceptable matrix effect in spite of use of a stable isotope analog internal standard. Rapid Commun. Mass Spectrom. 17(15), 1723-1734 (2003).
14. Li W, Cohen LH. Quantitation of endogenous analytes in biofluid without a true blank matrix. Anal. Chem. 75(21), 5854-5859 (2003).
15. Penner N, Ramanathan R, Zgoda-Pols J, Chowdhury S. Quantitative determination of hippuric and benzoic acids in urine by LC-MS/MS using surrogate standards. J. Pharm. Biomed. Anal. 52(4), 534-543 (2010).
16. Jones BR, Schultz GA, Eckstein JA, Ackermann BL. Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules. Bioanalysis 4(19), 2343-2356 (2012).
17. Exact Masses &Isotope Abundance Ratios.www.cem.msu.edu/~reusch/ OrgPage/mass.htm
18. Isotope Distribution Calculator and Mass Spec Plotter.www.sisweb.com/ mstools/isotope.htm
19. Rorabacher DB. Statistical treatment for rejection of deviant values: critical values of Dixon's "Q" parameter and related subrange ratios at the 95% confidence level. Anal. Chem. 63(2), 139-146 (1991).
20. Mayo Clinic. Creatine Disorders Panel, Urine. www. mayomedicallaboratories.com/test-catalog/Overview/88697